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The map label for this gene is perR [H]

Identifier: 138894164

GI number: 138894164

Start: 544941

End: 545393

Strand: Direct

Name: perR [H]

Synonym: GTNG_0490

Alternate gene names: 138894164

Gene position: 544941-545393 (Clockwise)

Preceding gene: 138894163

Following gene: 138894166

Centisome position: 15.35

GC content: 46.14

Gene sequence:

>453_bases
ATGACGGTGTCTGTCAACGAGCAACTGAAGGAAGCGCTGGACATGCTGAAAAAGACGGGCATACGCATCACGCCACAGCG
TCATGCGATATTGGAGTATTTGATCAGCTCGATGTCCCATCCGACGGCTGATGAAATATATAAAGCGCTCGAAGGGAAAT
TTCCTAATATGAGCGTAGCTACCGTCTACAATAACTTGCGCGTCTTTAAAGAGGTCGGGCTTGTCAAAGAGTTGACATAC
GGTGATTCGTCAAGCCGGTTCGATTTTGTCACATCCAATCATTATCACGTCATTTGTGAACAGTGTGGCAAAATCGTGGA
TTTTCATTATCCAGCGCTCGATGAAGTTGAGCAGCTAGCTGCTCATGTTACTGGATTTAAAGTCGATCATCATCGCATGG
AAGTGTATGGAGTATGCCCTGACTGTCAAAACGAGAAGGGGCGGACACATTAA

Upstream 100 bases:

>100_bases
TAATGGTATCTATATTGACAAAAGGCATACATTCCTTGTAGACTAATTATAAATATTATAAAATGATAATTTTTTTTATC
TTTTGCAGAGAGTGAGGTGC

Downstream 100 bases:

>100_bases
AAAAGCTGATAGCGCGACAGCGGCTATCAGTTTTTTCTTTTTTTATTGTATTTCTCATCGAATTCTTTTCCTTCAAGTTC
GCGATCCAACGTCAGGGGCT

Product: FUR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 150; Mature: 149

Protein sequence:

>150_residues
MTVSVNEQLKEALDMLKKTGIRITPQRHAILEYLISSMSHPTADEIYKALEGKFPNMSVATVYNNLRVFKEVGLVKELTY
GDSSSRFDFVTSNHYHVICEQCGKIVDFHYPALDEVEQLAAHVTGFKVDHHRMEVYGVCPDCQNEKGRTH

Sequences:

>Translated_150_residues
MTVSVNEQLKEALDMLKKTGIRITPQRHAILEYLISSMSHPTADEIYKALEGKFPNMSVATVYNNLRVFKEVGLVKELTY
GDSSSRFDFVTSNHYHVICEQCGKIVDFHYPALDEVEQLAAHVTGFKVDHHRMEVYGVCPDCQNEKGRTH
>Mature_149_residues
TVSVNEQLKEALDMLKKTGIRITPQRHAILEYLISSMSHPTADEIYKALEGKFPNMSVATVYNNLRVFKEVGLVKELTYG
DSSSRFDFVTSNHYHVICEQCGKIVDFHYPALDEVEQLAAHVTGFKVDHHRMEVYGVCPDCQNEKGRTH

Specific function: Hydrogen and organic peroxide sensor. Represses the expression of a regulon of peroxide-inducible genes such as katA, ahpC, ahpF, the heme biosynthesis operon (hemAXCDBL), fur, perR, zosA and mrgA [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=135, Percent_Identity=30.3703703703704, Blast_Score=70, Evalue=7e-14,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 17089; Mature: 16957

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVSVNEQLKEALDMLKKTGIRITPQRHAILEYLISSMSHPTADEIYKALEGKFPNMSVA
CCCCHHHHHHHHHHHHHHCCCEECCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHH
TVYNNLRVFKEVGLVKELTYGDSSSRFDFVTSNHYHVICEQCGKIVDFHYPALDEVEQLA
HHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHCCHHCCCCCCHHHHHHHH
AHVTGFKVDHHRMEVYGVCPDCQNEKGRTH
HHHHCCCCCCCEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure 
TVSVNEQLKEALDMLKKTGIRITPQRHAILEYLISSMSHPTADEIYKALEGKFPNMSVA
CCCHHHHHHHHHHHHHHCCCEECCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHH
TVYNNLRVFKEVGLVKELTYGDSSSRFDFVTSNHYHVICEQCGKIVDFHYPALDEVEQLA
HHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHCCHHCCCCCCHHHHHHHH
AHVTGFKVDHHRMEVYGVCPDCQNEKGRTH
HHHHCCCCCCCEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9202460; 9384377; 9701813; 12100544 [H]