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The map label for this gene is yfmP [H]

Identifier: 138894026

GI number: 138894026

Start: 402960

End: 403388

Strand: Reverse

Name: yfmP [H]

Synonym: GTNG_0352

Alternate gene names: 138894026

Gene position: 403388-402960 (Counterclockwise)

Preceding gene: 138894027

Following gene: 138894025

Centisome position: 11.36

GC content: 48.72

Gene sequence:

>429_bases
ATGGAACGATTGAAAATTGATGACGTCGCCAAAGCGACCGGCTTAACAAAGCGGGCGATCCGCTATTATGAAGAAATCGG
CTTGATCAAGCCGCCGGCACGGAGTGAGGGCGGCACACGCCTTTATACGCAGGAAGATATCGAGCAGCTGAAAAACATCG
TCGCCGCCCGCGAAGTGCTCGGTTTTTCGCTGCAGGAGTTACAGCACTTTTTAACATTGAAAGAAAAAATTGAGACGCAT
CGAGCAGAATACCGCCAAGCCATCGTTAGCAGCGAACAGCAGCGTGAACTCGAACAAATGGCCGCCGGGTTGCACCAACA
AATTGCCATGCTTGATGACAAAATGAAGAAAATGGCGACACTGAAACAAGAACTGAAACAAATGGCAGAGCAAATAGACG
CCATTCTAGAAGAGAGGAGAGAAGAATAG

Upstream 100 bases:

>100_bases
CCCATTCCAAATACCTATTGACAAAAATATAACGTTCACGTTAACGTTATATCTGTAGAAAACACCGTGTATCGCGATCA
CGCGAAAGTGAGGGCCCAGG

Downstream 100 bases:

>100_bases
TGGAGGAAAGAAAACAAACACGGGCGCGCTGGATTACCGTTGCCGCCGCCTTTTTGGCGTTTATGGGTATCGGGGTCGTC
GATCCGATTTTGCCGGTCAT

Product: MerR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 142; Mature: 142

Protein sequence:

>142_residues
MERLKIDDVAKATGLTKRAIRYYEEIGLIKPPARSEGGTRLYTQEDIEQLKNIVAAREVLGFSLQELQHFLTLKEKIETH
RAEYRQAIVSSEQQRELEQMAAGLHQQIAMLDDKMKKMATLKQELKQMAEQIDAILEERREE

Sequences:

>Translated_142_residues
MERLKIDDVAKATGLTKRAIRYYEEIGLIKPPARSEGGTRLYTQEDIEQLKNIVAAREVLGFSLQELQHFLTLKEKIETH
RAEYRQAIVSSEQQRELEQMAAGLHQQIAMLDDKMKKMATLKQELKQMAEQIDAILEERREE
>Mature_142_residues
MERLKIDDVAKATGLTKRAIRYYEEIGLIKPPARSEGGTRLYTQEDIEQLKNIVAAREVLGFSLQELQHFLTLKEKIETH
RAEYRQAIVSSEQQRELEQMAAGLHQQIAMLDDKMKKMATLKQELKQMAEQIDAILEERREE

Specific function: Repressor of the yfmOP operon. A mutation in yfmP leads to overexpression of yfmO, probably causing a decrease in cellular copper that is eventually responsible for a reduced copper induction of copZA [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786695, Length=111, Percent_Identity=38.7387387387387, Blast_Score=77, Evalue=4e-16,
Organism=Escherichia coli, GI1789687, Length=85, Percent_Identity=38.8235294117647, Blast_Score=61, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551 [H]

Pfam domain/function: PF00376 MerR [H]

EC number: NA

Molecular weight: Translated: 16512; Mature: 16512

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERLKIDDVAKATGLTKRAIRYYEEIGLIKPPARSEGGTRLYTQEDIEQLKNIVAAREVL
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
GFSLQELQHFLTLKEKIETHRAEYRQAIVSSEQQRELEQMAAGLHQQIAMLDDKMKKMAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKQELKQMAEQIDAILEERREE
HHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MERLKIDDVAKATGLTKRAIRYYEEIGLIKPPARSEGGTRLYTQEDIEQLKNIVAAREVL
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
GFSLQELQHFLTLKEKIETHRAEYRQAIVSSEQQRELEQMAAGLHQQIAMLDDKMKKMAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKQELKQMAEQIDAILEERREE
HHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]