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The map label for this gene is yfmO [H]

Identifier: 138894025

GI number: 138894025

Start: 401803

End: 402960

Strand: Reverse

Name: yfmO [H]

Synonym: GTNG_0351

Alternate gene names: 138894025

Gene position: 402960-401803 (Counterclockwise)

Preceding gene: 138894026

Following gene: 138894017

Centisome position: 11.35

GC content: 52.25

Gene sequence:

>1158_bases
GTGGAGGAAAGAAAACAAACACGGGCGCGCTGGATTACCGTTGCCGCCGCCTTTTTGGCGTTTATGGGTATCGGGGTCGT
CGATCCGATTTTGCCGGTCATCGCCGAAAGCATCGGCGCGACCCACTGGCAAGTGGAAATGTTGTTTACCGCCTATATTT
TTACGATGGCGGTCATGATGATTCCCGTTGGACTTGTCGTCAGCCGCGTTGGTGATAAACAAATGATGGTGATCGGACTT
GGCCTTGTCACGATTTTCTCATTATTGTGCGGTTTTGCCGCCGACATCCCACAACTGTCGATCTTCCGCGCCGGTTGGGG
GCTTGGCAATGCCACCTTTTTTGCAACGGCTATGACACTGTTAATCGCTTTGACGCCGCAGGCAAGCACCGCTGTCGGCT
TGTATGAGGCGGCGATCGGCCTCGGCATGGCCGGTGGTCCGCTCATCGGTGGACTGCTGGGCCAACATTCATGGCGCTAC
CCGTTTATCGGCACAAGCGTGCTCATTTTTATCGCCTTTTTGCTTGTCGCATTTTTTGTGTATGATCCAAACAAAGGAAA
ACCGAAAAAAGCAGTCGGATGGCAGGAAATGCGGCATCTGCTCGCCTTTCCGCCGTTTTTAAAAGGGGCGATCGGCGGGA
TGCTTTATTATTACGGCTTTTTCGTTGTTTTGGCCTATTCGCCTCTGGTCATTAAGTTATCGGCGATTCAAATCGGTCTT
GTCTTTTTCGGCTGGGGGCTTTGCCTCGCCTACGGATCGGCAGCGTTGGCCCACCGACTTGAAACAAAATACGAACCGAA
ACAAATATTGCCTTACAGCTTATTGCTGTTTGCCGTTTTATTGCTGCTTTTAGCGGTCGCTGAACAAACATGGTTCATGA
TCGTCCTTATCATTTTGTCGGGCCTTGTATCCGGCTTAAACAACGCCTTGTTTACAGGCTATGTGATGGAAACATCGCCG
TATGAACGCGGCGTCACTTCCGGCATGTACAACTTCGTTCGCTGGATGGGGGCGGCCATCGCTCCGGTGCTATCTGGCGT
CATCGGTCACGCCGTTTCCGCAAAGGCGCCGTTTATGATCGCCATGGCGCTGTCGCTTGTTGCATTCCTTTTCCTTGCCT
GGCGCAAACGGGAGCCATCGGCAACGAAAACTGTATAA

Upstream 100 bases:

>100_bases
TGCTTGATGACAAAATGAAGAAAATGGCGACACTGAAACAAGAACTGAAACAAATGGCAGAGCAAATAGACGCCATTCTA
GAAGAGAGGAGAGAAGAATA

Downstream 100 bases:

>100_bases
AAGCAACCGTTGCGGACAAAACGAAAACACGCCCGTTTCTCGGTGAGAAACAGGCGTGTTTTTATTCGGATCATTGTCAT
CATCTCTTATCATCACTCTA

Product: multidrug resistance protein

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MEERKQTRARWITVAAAFLAFMGIGVVDPILPVIAESIGATHWQVEMLFTAYIFTMAVMMIPVGLVVSRVGDKQMMVIGL
GLVTIFSLLCGFAADIPQLSIFRAGWGLGNATFFATAMTLLIALTPQASTAVGLYEAAIGLGMAGGPLIGGLLGQHSWRY
PFIGTSVLIFIAFLLVAFFVYDPNKGKPKKAVGWQEMRHLLAFPPFLKGAIGGMLYYYGFFVVLAYSPLVIKLSAIQIGL
VFFGWGLCLAYGSAALAHRLETKYEPKQILPYSLLLFAVLLLLLAVAEQTWFMIVLIILSGLVSGLNNALFTGYVMETSP
YERGVTSGMYNFVRWMGAAIAPVLSGVIGHAVSAKAPFMIAMALSLVAFLFLAWRKREPSATKTV

Sequences:

>Translated_385_residues
MEERKQTRARWITVAAAFLAFMGIGVVDPILPVIAESIGATHWQVEMLFTAYIFTMAVMMIPVGLVVSRVGDKQMMVIGL
GLVTIFSLLCGFAADIPQLSIFRAGWGLGNATFFATAMTLLIALTPQASTAVGLYEAAIGLGMAGGPLIGGLLGQHSWRY
PFIGTSVLIFIAFLLVAFFVYDPNKGKPKKAVGWQEMRHLLAFPPFLKGAIGGMLYYYGFFVVLAYSPLVIKLSAIQIGL
VFFGWGLCLAYGSAALAHRLETKYEPKQILPYSLLLFAVLLLLLAVAEQTWFMIVLIILSGLVSGLNNALFTGYVMETSP
YERGVTSGMYNFVRWMGAAIAPVLSGVIGHAVSAKAPFMIAMALSLVAFLFLAWRKREPSATKTV
>Mature_385_residues
MEERKQTRARWITVAAAFLAFMGIGVVDPILPVIAESIGATHWQVEMLFTAYIFTMAVMMIPVGLVVSRVGDKQMMVIGL
GLVTIFSLLCGFAADIPQLSIFRAGWGLGNATFFATAMTLLIALTPQASTAVGLYEAAIGLGMAGGPLIGGLLGQHSWRY
PFIGTSVLIFIAFLLVAFFVYDPNKGKPKKAVGWQEMRHLLAFPPFLKGAIGGMLYYYGFFVVLAYSPLVIKLSAIQIGL
VFFGWGLCLAYGSAALAHRLETKYEPKQILPYSLLLFAVLLLLLAVAEQTWFMIVLIILSGLVSGLNNALFTGYVMETSP
YERGVTSGMYNFVRWMGAAIAPVLSGVIGHAVSAKAPFMIAMALSLVAFLFLAWRKREPSATKTV

Specific function: Acts to efflux copper or a copper complex. It is possible that yfmO could contribute to copper resistance [H]

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001958 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 41765; Mature: 41765

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEERKQTRARWITVAAAFLAFMGIGVVDPILPVIAESIGATHWQVEMLFTAYIFTMAVMM
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
IPVGLVVSRVGDKQMMVIGLGLVTIFSLLCGFAADIPQLSIFRAGWGLGNATFFATAMTL
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCHHHHHHHHHHH
LIALTPQASTAVGLYEAAIGLGMAGGPLIGGLLGQHSWRYPFIGTSVLIFIAFLLVAFFV
HHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
YDPNKGKPKKAVGWQEMRHLLAFPPFLKGAIGGMLYYYGFFVVLAYSPLVIKLSAIQIGL
CCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHEEHHHHHHHH
VFFGWGLCLAYGSAALAHRLETKYEPKQILPYSLLLFAVLLLLLAVAEQTWFMIVLIILS
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLVSGLNNALFTGYVMETSPYERGVTSGMYNFVRWMGAAIAPVLSGVIGHAVSAKAPFMI
HHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
AMALSLVAFLFLAWRKREPSATKTV
HHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]