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The map label for this gene is divL [H]

Identifier: 13474243

GI number: 13474243

Start: 4030308

End: 4032863

Strand: Reverse

Name: divL [H]

Synonym: mll5087

Alternate gene names: 13474243

Gene position: 4032863-4030308 (Counterclockwise)

Preceding gene: 13474244

Following gene: 13474242

Centisome position: 57.32

GC content: 65.88

Gene sequence:

>2556_bases
ATGCCGGGGCAAAACCCGCACGGAGCGGGATCGGCCGTTTCCGGCGGCCATGACGATTCGGGGATCACAGGCTCGACCAT
TCAGGGCGTGCGCCTTTCATGGCGTGCCCGCGCCGGGCTGTTCCTGACCAGTTCCGTGCTGGCCGGCCCCCTGGCCAGCG
CCGTGGCGCATGCCGAGAACGCTGCCGTCGCCACCGCCGGCCTGTCGATCAACACGGTCGAAGTCATGCAGCTTGCCGTG
TTCGTCGGCGTGACGGGCGCGGCATTCCTGTCGGCCATCGTTCTCATCCGCGAACGGGCCCGCACCTCGGCGGAGAATGT
CGAACTGAGAAGCCGCGTCGCCGATATCAATGCGGCACTGCGCCGTTCGGAAGCGCTTCTCAATCTGCGCGACCAGCGCG
TGGTGGTCTGGGCCTCGGAAAACAAGAAGCCCGAACTCATCGGCACATTGCCGGTCGAGAGCGGCGCGCCAGAGGAACGG
TCGGCTTTCCTCGCCTTCGGCCGCTGGTTGATGCCGCGCTCGGCGGCGGCGCTCGAGCACGCCATTGCGGGCTTGCGCGA
AAAGGCCAGGCCCTTCGACCTCGTCATCGAATCGCAGGCCGGCGCGCCGCTCGAAGTGCATGGCCGCAAGAGCGCCGCGC
ACATACTGGTGCGGTTTGTGTCGCTTTCCGAGACCCAGCGCAGCCAGGCCCGGCTGAAGATCGACAACCAGCGGCTGGCC
GCCGACCATGACACGATGATCGGTCTGCTCGAAGCGCTGAAGATGCCGGCATGGCTGCGCGACGAGCATGGACGCCTGAA
ATGGGTCAACCGGGCCTATGCCGACGCGGTCGAAGCCGAAAGCGCGGAAGCCGCCGTCCGCGACGCCAGGGAATTCCTCG
GGGGCCAGGCACGCGAGGCGATAGACGCCCAGCACAAGACGCATCCGGTCTTCGAGCAGTCGCTATCCACGGTGATCGAA
GGCGACCGCCGCGTCTTCGCGGTGACCGACTTCGCCAGCCCGGACGGTTCGGCCGGTCTTGCCGCCGACACCAGCGCCAT
CGAGGCCATTCGAGGTGAATATGAGCGCACGGTGCGCAGCCATGCCGACACGCTCGACCAGCTCAACACCGCTGTCGCCA
TCTTCGACACCGACGAGAAGCTGCGCTTCTTCAACCAGGCCTTCCAGAAACTGTGGGGGCTGGACAGCGGCTTCCTGCAC
AGCGCGCCCGACAATGCGCTTCTGCTCGACCGGCTGCGCAGCGAAGGCAAGATCGCCGAGCAGCCCGAATGGCGCCGCTG
GAAGGAAGGCCTGCTCGGCGCCTACCGCGCGGTGGAATCGCAGGAACATTGGTGGCATCTGCCTGACGGCAAGACCATCC
GCGTCGTCGCCAATCCGCAGCCCAAGGGCGGCGTCACCTGGGTGTTCGAGAACCTGACCGAGAAGATGGACCTGGAAAGC
CGCTACCGCACCGCGGTGCGCGTCCAGGGCGAAACGCTCGACAATCTCGCCGAAGGCGTGGCGGTGTTCGGGCCTGATGG
TCGGCTGCGCCTGTCGAACCCGGCCTTTGCCACACTCTGGGGATTGAGCGGCGAAGCCGCCAAGCCCAATGTGCACGTCT
CCACGATACGCGACCTTTGCGACCGCCAGGCGGTCGACAGCCCCTGGCCCGGTTTCGTCGCCGCCATCACCGGTTTCGAC
GACGAGCGCCGCGACCGGCACGGCCAGAGCGAGCTCAACAACGGCACCGTGCTGCGCTATGCCGTGATCCCGCTGCCCAA
CGGGCAAGTGATGATGACCTTCGTCGATGTCACCGACAGCGTCCATGTCGAACGTGCGCTGAAGGACAAGAACGAGGCGC
TGGAGAAGTCGGACCAGCTCAAGAACGACTTCGTCCAGCACGTGTCCTACGAACTGCGTTCGCCGCTGACCAACATCATC
GGCTTCACCGAACTGCTTTCACTGCCCACGACCGGACCGCTGAATCAAAAGCAGCGCGAATATGTCGAGCATGTCAGTTC
GTCCTCCTCGGTGCTGCTGACCATCGTCAACGACATACTCGACCTCGCGACCGTCGACGCCGGCATCATGCAGCTCGACA
TTTCCGAGGTGCATGTCGACCGCACCATCGCGGCGGCCGCGGAACTGGTTGCCGACCGGCTGCAGGAGCATTCGATCCGG
CTCGAAGTCGATGCCCGTGCCGCGCCGAAGACGTTCCACGGCGACGAGATCCGCATCCGTCAGATCCTCTACAATCTGCT
CAGCAACGCCGCCAACTACGCGCCGGAAGCCAGCACCATCCGGCTCGCCTGCCGCCATCTGGCGGACGGGGTGGAATTTT
CCGTTCACGACGACGGCCCCGGCATGCCGCCGGACGTGCTGGATTCGGTGTTCCGCCGCTTCGAACCGCGCGCCAATGGC
GGCCGCCGGCGGGGCGCCGGCCTCGGCCTGTCGATCGTCAAGAGCTTTGTCGAACTGCATGGCGGCAATGTTCGCATCGA
AACCGGCAAGGACAAGGGCACGACCGTCATCTGCACCTTCCCCGACATGCCGGGCATCCGCGCCGCGGCCGAGTAG

Upstream 100 bases:

>100_bases
GTTTATTGTCAGGTGATTCGCGACGCTTCCGGCCCGAGAGGGGATCAGAGAGGCGCGTATCAGGGCGGTCTTGCATTCAG
GCGGCGGAGAGGACCAAGAC

Downstream 100 bases:

>100_bases
CGCGCTCTATGACGGGACCTGTACTGGAGCATTTGCTCGCGGATGAGACACAGACAGCGCGACTGGGCGAAGATCTGGCG
TTGTCCCTGCGCGCCGGCGA

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 851; Mature: 850

Protein sequence:

>851_residues
MPGQNPHGAGSAVSGGHDDSGITGSTIQGVRLSWRARAGLFLTSSVLAGPLASAVAHAENAAVATAGLSINTVEVMQLAV
FVGVTGAAFLSAIVLIRERARTSAENVELRSRVADINAALRRSEALLNLRDQRVVVWASENKKPELIGTLPVESGAPEER
SAFLAFGRWLMPRSAAALEHAIAGLREKARPFDLVIESQAGAPLEVHGRKSAAHILVRFVSLSETQRSQARLKIDNQRLA
ADHDTMIGLLEALKMPAWLRDEHGRLKWVNRAYADAVEAESAEAAVRDAREFLGGQAREAIDAQHKTHPVFEQSLSTVIE
GDRRVFAVTDFASPDGSAGLAADTSAIEAIRGEYERTVRSHADTLDQLNTAVAIFDTDEKLRFFNQAFQKLWGLDSGFLH
SAPDNALLLDRLRSEGKIAEQPEWRRWKEGLLGAYRAVESQEHWWHLPDGKTIRVVANPQPKGGVTWVFENLTEKMDLES
RYRTAVRVQGETLDNLAEGVAVFGPDGRLRLSNPAFATLWGLSGEAAKPNVHVSTIRDLCDRQAVDSPWPGFVAAITGFD
DERRDRHGQSELNNGTVLRYAVIPLPNGQVMMTFVDVTDSVHVERALKDKNEALEKSDQLKNDFVQHVSYELRSPLTNII
GFTELLSLPTTGPLNQKQREYVEHVSSSSSVLLTIVNDILDLATVDAGIMQLDISEVHVDRTIAAAAELVADRLQEHSIR
LEVDARAAPKTFHGDEIRIRQILYNLLSNAANYAPEASTIRLACRHLADGVEFSVHDDGPGMPPDVLDSVFRRFEPRANG
GRRRGAGLGLSIVKSFVELHGGNVRIETGKDKGTTVICTFPDMPGIRAAAE

Sequences:

>Translated_851_residues
MPGQNPHGAGSAVSGGHDDSGITGSTIQGVRLSWRARAGLFLTSSVLAGPLASAVAHAENAAVATAGLSINTVEVMQLAV
FVGVTGAAFLSAIVLIRERARTSAENVELRSRVADINAALRRSEALLNLRDQRVVVWASENKKPELIGTLPVESGAPEER
SAFLAFGRWLMPRSAAALEHAIAGLREKARPFDLVIESQAGAPLEVHGRKSAAHILVRFVSLSETQRSQARLKIDNQRLA
ADHDTMIGLLEALKMPAWLRDEHGRLKWVNRAYADAVEAESAEAAVRDAREFLGGQAREAIDAQHKTHPVFEQSLSTVIE
GDRRVFAVTDFASPDGSAGLAADTSAIEAIRGEYERTVRSHADTLDQLNTAVAIFDTDEKLRFFNQAFQKLWGLDSGFLH
SAPDNALLLDRLRSEGKIAEQPEWRRWKEGLLGAYRAVESQEHWWHLPDGKTIRVVANPQPKGGVTWVFENLTEKMDLES
RYRTAVRVQGETLDNLAEGVAVFGPDGRLRLSNPAFATLWGLSGEAAKPNVHVSTIRDLCDRQAVDSPWPGFVAAITGFD
DERRDRHGQSELNNGTVLRYAVIPLPNGQVMMTFVDVTDSVHVERALKDKNEALEKSDQLKNDFVQHVSYELRSPLTNII
GFTELLSLPTTGPLNQKQREYVEHVSSSSSVLLTIVNDILDLATVDAGIMQLDISEVHVDRTIAAAAELVADRLQEHSIR
LEVDARAAPKTFHGDEIRIRQILYNLLSNAANYAPEASTIRLACRHLADGVEFSVHDDGPGMPPDVLDSVFRRFEPRANG
GRRRGAGLGLSIVKSFVELHGGNVRIETGKDKGTTVICTFPDMPGIRAAAE
>Mature_850_residues
PGQNPHGAGSAVSGGHDDSGITGSTIQGVRLSWRARAGLFLTSSVLAGPLASAVAHAENAAVATAGLSINTVEVMQLAVF
VGVTGAAFLSAIVLIRERARTSAENVELRSRVADINAALRRSEALLNLRDQRVVVWASENKKPELIGTLPVESGAPEERS
AFLAFGRWLMPRSAAALEHAIAGLREKARPFDLVIESQAGAPLEVHGRKSAAHILVRFVSLSETQRSQARLKIDNQRLAA
DHDTMIGLLEALKMPAWLRDEHGRLKWVNRAYADAVEAESAEAAVRDAREFLGGQAREAIDAQHKTHPVFEQSLSTVIEG
DRRVFAVTDFASPDGSAGLAADTSAIEAIRGEYERTVRSHADTLDQLNTAVAIFDTDEKLRFFNQAFQKLWGLDSGFLHS
APDNALLLDRLRSEGKIAEQPEWRRWKEGLLGAYRAVESQEHWWHLPDGKTIRVVANPQPKGGVTWVFENLTEKMDLESR
YRTAVRVQGETLDNLAEGVAVFGPDGRLRLSNPAFATLWGLSGEAAKPNVHVSTIRDLCDRQAVDSPWPGFVAAITGFDD
ERRDRHGQSELNNGTVLRYAVIPLPNGQVMMTFVDVTDSVHVERALKDKNEALEKSDQLKNDFVQHVSYELRSPLTNIIG
FTELLSLPTTGPLNQKQREYVEHVSSSSSVLLTIVNDILDLATVDAGIMQLDISEVHVDRTIAAAAELVADRLQEHSIRL
EVDARAAPKTFHGDEIRIRQILYNLLSNAANYAPEASTIRLACRHLADGVEFSVHDDGPGMPPDVLDSVFRRFEPRANGG
RRRGAGLGLSIVKSFVELHGGNVRIETGKDKGTTVICTFPDMPGIRAAAE

Specific function: Required for cell division and growth. It catalyzes the phosphorylation of CtrA and activates transcription in vitro of the cell cycle-regulated fliF promoter [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=238, Percent_Identity=30.672268907563, Blast_Score=108, Evalue=2e-24,
Organism=Escherichia coli, GI1786600, Length=278, Percent_Identity=29.136690647482, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI145693157, Length=257, Percent_Identity=29.1828793774319, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI87081816, Length=232, Percent_Identity=31.8965517241379, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1789149, Length=228, Percent_Identity=29.3859649122807, Blast_Score=99, Evalue=8e-22,
Organism=Escherichia coli, GI1788713, Length=316, Percent_Identity=27.2151898734177, Blast_Score=96, Evalue=9e-21,
Organism=Escherichia coli, GI1786912, Length=228, Percent_Identity=27.1929824561404, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1788393, Length=232, Percent_Identity=26.2931034482759, Blast_Score=87, Evalue=6e-18,
Organism=Escherichia coli, GI1790436, Length=215, Percent_Identity=26.5116279069767, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1786783, Length=251, Percent_Identity=26.6932270916335, Blast_Score=80, Evalue=7e-16,
Organism=Escherichia coli, GI1790861, Length=258, Percent_Identity=25.1937984496124, Blast_Score=76, Evalue=1e-14,
Organism=Escherichia coli, GI87082128, Length=234, Percent_Identity=27.3504273504274, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1789403, Length=212, Percent_Identity=29.7169811320755, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1788279, Length=224, Percent_Identity=25.8928571428571, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1790346, Length=232, Percent_Identity=25, Blast_Score=70, Evalue=8e-13,
Organism=Escherichia coli, GI1790551, Length=219, Percent_Identity=27.3972602739726, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 92983; Mature: 92852

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGQNPHGAGSAVSGGHDDSGITGSTIQGVRLSWRARAGLFLTSSVLAGPLASAVAHAEN
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEHHCCCHHHHHHHHHHHHHHHHHHHCC
AAVATAGLSINTVEVMQLAVFVGVTGAAFLSAIVLIRERARTSAENVELRSRVADINAAL
CEEEECCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
RRSEALLNLRDQRVVVWASENKKPELIGTLPVESGAPEERSAFLAFGRWLMPRSAAALEH
HHHHHHHCCCCCEEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCHHHHHHH
AIAGLREKARPFDLVIESQAGAPLEVHGRKSAAHILVRFVSLSETQRSQARLKIDNQRLA
HHHHHHHHCCCEEEEEECCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCC
ADHDTMIGLLEALKMPAWLRDEHGRLKWVNRAYADAVEAESAEAAVRDAREFLGGQAREA
CCHHHHHHHHHHHCCCCHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
IDAQHKTHPVFEQSLSTVIEGDRRVFAVTDFASPDGSAGLAADTSAIEAIRGEYERTVRS
HHHHHCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
HADTLDQLNTAVAIFDTDEKLRFFNQAFQKLWGLDSGFLHSAPDNALLLDRLRSEGKIAE
HHHHHHHHCCEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCC
QPEWRRWKEGLLGAYRAVESQEHWWHLPDGKTIRVVANPQPKGGVTWVFENLTEKMDLES
CCCHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEEEECCCCCCCEEHHHHHHHHHHCHHH
RYRTAVRVQGETLDNLAEGVAVFGPDGRLRLSNPAFATLWGLSGEAAKPNVHVSTIRDLC
HHCEEEEECCCHHHHHHCCEEEECCCCCEEECCCCEEEEECCCCCCCCCCCHHHHHHHHH
DRQAVDSPWPGFVAAITGFDDERRDRHGQSELNNGTVLRYAVIPLPNGQVMMTFVDVTDS
HHHCCCCCCCCCEEEEECCCHHHHHCCCHHHCCCCEEEEEEEEECCCCCEEEEEEECCCC
VHVERALKDKNEALEKSDQLKNDFVQHVSYELRSPLTNIIGFTELLSLPTTGPLNQKQRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
YVEHVSSSSSVLLTIVNDILDLATVDAGIMQLDISEVHVDRTIAAAAELVADRLQEHSIR
HHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCEE
LEVDARAAPKTFHGDEIRIRQILYNLLSNAANYAPEASTIRLACRHLADGVEFSVHDDGP
EEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCC
GMPPDVLDSVFRRFEPRANGGRRRGAGLGLSIVKSFVELHGGNVRIETGKDKGTTVICTF
CCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCEEEEEC
PDMPGIRAAAE
CCCCCCCCCCC
>Mature Secondary Structure 
PGQNPHGAGSAVSGGHDDSGITGSTIQGVRLSWRARAGLFLTSSVLAGPLASAVAHAEN
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEHHCCCHHHHHHHHHHHHHHHHHHHCC
AAVATAGLSINTVEVMQLAVFVGVTGAAFLSAIVLIRERARTSAENVELRSRVADINAAL
CEEEECCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
RRSEALLNLRDQRVVVWASENKKPELIGTLPVESGAPEERSAFLAFGRWLMPRSAAALEH
HHHHHHHCCCCCEEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCHHHHHHH
AIAGLREKARPFDLVIESQAGAPLEVHGRKSAAHILVRFVSLSETQRSQARLKIDNQRLA
HHHHHHHHCCCEEEEEECCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCC
ADHDTMIGLLEALKMPAWLRDEHGRLKWVNRAYADAVEAESAEAAVRDAREFLGGQAREA
CCHHHHHHHHHHHCCCCHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
IDAQHKTHPVFEQSLSTVIEGDRRVFAVTDFASPDGSAGLAADTSAIEAIRGEYERTVRS
HHHHHCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
HADTLDQLNTAVAIFDTDEKLRFFNQAFQKLWGLDSGFLHSAPDNALLLDRLRSEGKIAE
HHHHHHHHCCEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCC
QPEWRRWKEGLLGAYRAVESQEHWWHLPDGKTIRVVANPQPKGGVTWVFENLTEKMDLES
CCCHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEEEECCCCCCCEEHHHHHHHHHHCHHH
RYRTAVRVQGETLDNLAEGVAVFGPDGRLRLSNPAFATLWGLSGEAAKPNVHVSTIRDLC
HHCEEEEECCCHHHHHHCCEEEECCCCCEEECCCCEEEEECCCCCCCCCCCHHHHHHHHH
DRQAVDSPWPGFVAAITGFDDERRDRHGQSELNNGTVLRYAVIPLPNGQVMMTFVDVTDS
HHHCCCCCCCCCEEEEECCCHHHHHCCCHHHCCCCEEEEEEEEECCCCCEEEEEEECCCC
VHVERALKDKNEALEKSDQLKNDFVQHVSYELRSPLTNIIGFTELLSLPTTGPLNQKQRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
YVEHVSSSSSVLLTIVNDILDLATVDAGIMQLDISEVHVDRTIAAAAELVADRLQEHSIR
HHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCEE
LEVDARAAPKTFHGDEIRIRQILYNLLSNAANYAPEASTIRLACRHLADGVEFSVHDDGP
EEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCC
GMPPDVLDSVFRRFEPRANGGRRRGAGLGLSIVKSFVELHGGNVRIETGKDKGTTVICTF
CCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCEEEEEC
PDMPGIRAAAE
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10557274; 11259647 [H]