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The map label for this gene is yleA [C]

Identifier: 13473651

GI number: 13473651

Start: 3437210

End: 3438550

Strand: Direct

Name: yleA [C]

Synonym: mlr4319

Alternate gene names: 13473651

Gene position: 3437210-3438550 (Clockwise)

Preceding gene: 13473650

Following gene: 13473652

Centisome position: 48.85

GC content: 64.88

Gene sequence:

>1341_bases
ATGTCGGTTGCTCTGCCCAGGAGCCCGGACGTCGACGGCTCCCTTTCCGAGGCCCCCAACCGCATTGACGTGGTGACATT
CGGCTGCCGGCTGAACACCTATGAATCCGAAGTGATGCGACGCGAGGCCGAAAGCGCCGGTCTTGGCGCGCTGCAAGGCG
GCGCCGTGATCTTCAACACCTGCGCCGTCACCGGCGAGGCGGTGCGCCAGGCCAGGCAGGCGATCCGCAAGGCGCGCCGC
GACAACCCTGGGGCGCGCATCATCGTCACCGGCTGCGCCGCGCAGACCGAGCCGGAAAAATTCGCCGCCATGGACGAGGT
CGATCTCGTGCTTGGCAATGAAGAGAAGCTGAAGGCAAACTCGTACCGCGCGCTGCCGGATTTCGGCGTCAACGACACCG
AGAAGGCCCGCGTCAACGACATCTTCTCGGTGCGCGAGACCGCCGGCCACATGGTCGACGCCATAGAAGGCCGCGCCCGC
GCCTTCGTGCAGGTGCAGAATGGCTGCGACCACCGCTGCACCTTCTGCATCATTCCTTACGGTCGCGGCAATTCGCGCTC
GGTGCCGATGGGCGCCGTGGTCGAGCAGGTCAAGCGGCTCGCCGGCAACGGCTATGCCGAGATCGTGCTGACCGGCGTCG
ACATGACCAGCTTCGGCGCCGATCTGCCGGGAGCGCCAAAACTCGGCAGACTGGTGAAGACCATTCTGAAGCAGGTGCCT
GACGTGAAGCGCCTGCGGCTATCTTCGATCGATTCCATCGAGGCCGACGACGATTTGCTCGATGCCATCGCCACCGAACC
CAGGCTGATGCCGCATTTGCATCTGTCGTTACAGTCCGGCGACGACATGATCCTGAAGCGCATGAAGCGAAGGCATCTGC
GCGACCAGTCGATCCGTTTCTGCGAGGATGTGCGCAAATTGCGTCCTGAAATCGTCTTCGGCGCCGACATCATCGCCGGC
TTCCCGACCGAGACCGACGCCATGTTCGAGAACTCGATAAAAATCGTCGAGGAATGTGGCCTGACCCATCTCCATGTTTT
CCCGTTTTCACCGCGCGAGGGCACGCCCGCCGCGCGCATGCCACAGGTCCGCCGCGAGGTGGTCAAGCAGCGCGCCGCCC
GTTTGCGCGCCGCCGGCGAAGCCGCCTATCGGCGCCATCTGTCCTCGCTGCCTGGAACCCGTCAGTCGATCCTGATCGAG
CGCGATGGTCTCGGTCGCACCGAAGGATTTACCCTCGCCGCACTCGGCACCGGCGCGCCCGGCGAGATCGTCGAAGCGAC
AATTACTGGCCACGATGGCGCCCGGCTCAACGCAGTGCCGCTTGCCGCACGCGCCGCCTGA

Upstream 100 bases:

>100_bases
ACGACCACGTCATCCTGACCGGTGCCGCCGAGTGGGAATTTTCCGGCAGCTTCGATCCCTCGACCGGCACCTGGGCCCGC
GACACCGAAAGCGCGGCCTG

Downstream 100 bases:

>100_bases
GAAACGCAAAGCATGGCTGGTTTTTTCAAGAAGATATTTTCGTTCGGCAAGAAAGAGGTTGTCGAGGAGCGCGTCGACGA
GACCGCCCCGCTGCCCCCGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 445

Protein sequence:

>446_residues
MSVALPRSPDVDGSLSEAPNRIDVVTFGCRLNTYESEVMRREAESAGLGALQGGAVIFNTCAVTGEAVRQARQAIRKARR
DNPGARIIVTGCAAQTEPEKFAAMDEVDLVLGNEEKLKANSYRALPDFGVNDTEKARVNDIFSVRETAGHMVDAIEGRAR
AFVQVQNGCDHRCTFCIIPYGRGNSRSVPMGAVVEQVKRLAGNGYAEIVLTGVDMTSFGADLPGAPKLGRLVKTILKQVP
DVKRLRLSSIDSIEADDDLLDAIATEPRLMPHLHLSLQSGDDMILKRMKRRHLRDQSIRFCEDVRKLRPEIVFGADIIAG
FPTETDAMFENSIKIVEECGLTHLHVFPFSPREGTPAARMPQVRREVVKQRAARLRAAGEAAYRRHLSSLPGTRQSILIE
RDGLGRTEGFTLAALGTGAPGEIVEATITGHDGARLNAVPLAARAA

Sequences:

>Translated_446_residues
MSVALPRSPDVDGSLSEAPNRIDVVTFGCRLNTYESEVMRREAESAGLGALQGGAVIFNTCAVTGEAVRQARQAIRKARR
DNPGARIIVTGCAAQTEPEKFAAMDEVDLVLGNEEKLKANSYRALPDFGVNDTEKARVNDIFSVRETAGHMVDAIEGRAR
AFVQVQNGCDHRCTFCIIPYGRGNSRSVPMGAVVEQVKRLAGNGYAEIVLTGVDMTSFGADLPGAPKLGRLVKTILKQVP
DVKRLRLSSIDSIEADDDLLDAIATEPRLMPHLHLSLQSGDDMILKRMKRRHLRDQSIRFCEDVRKLRPEIVFGADIIAG
FPTETDAMFENSIKIVEECGLTHLHVFPFSPREGTPAARMPQVRREVVKQRAARLRAAGEAAYRRHLSSLPGTRQSILIE
RDGLGRTEGFTLAALGTGAPGEIVEATITGHDGARLNAVPLAARAA
>Mature_445_residues
SVALPRSPDVDGSLSEAPNRIDVVTFGCRLNTYESEVMRREAESAGLGALQGGAVIFNTCAVTGEAVRQARQAIRKARRD
NPGARIIVTGCAAQTEPEKFAAMDEVDLVLGNEEKLKANSYRALPDFGVNDTEKARVNDIFSVRETAGHMVDAIEGRARA
FVQVQNGCDHRCTFCIIPYGRGNSRSVPMGAVVEQVKRLAGNGYAEIVLTGVDMTSFGADLPGAPKLGRLVKTILKQVPD
VKRLRLSSIDSIEADDDLLDAIATEPRLMPHLHLSLQSGDDMILKRMKRRHLRDQSIRFCEDVRKLRPEIVFGADIIAGF
PTETDAMFENSIKIVEECGLTHLHVFPFSPREGTPAARMPQVRREVVKQRAARLRAAGEAAYRRHLSSLPGTRQSILIER
DGLGRTEGFTLAALGTGAPGEIVEATITGHDGARLNAVPLAARAA

Specific function: Unknown

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MTTase N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI93277076, Length=414, Percent_Identity=28.0193236714976, Blast_Score=155, Evalue=6e-38,
Organism=Homo sapiens, GI28872782, Length=375, Percent_Identity=24.8, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI28872784, Length=375, Percent_Identity=24.5333333333333, Blast_Score=122, Evalue=5e-28,
Organism=Escherichia coli, GI1786882, Length=437, Percent_Identity=28.604118993135, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1787057, Length=367, Percent_Identity=29.700272479564, Blast_Score=145, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI17553146, Length=463, Percent_Identity=28.5097192224622, Blast_Score=159, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI71996771, Length=367, Percent_Identity=26.158038147139, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI21356207, Length=426, Percent_Identity=26.7605633802817, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI19922432, Length=383, Percent_Identity=27.4151436031332, Blast_Score=141, Evalue=7e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR006467
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM; PF00919 UPF0004 [H]

EC number: NA

Molecular weight: Translated: 48482; Mature: 48351

Theoretical pI: Translated: 8.02; Mature: 8.02

Prosite motif: PS01278 UPF0004

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVALPRSPDVDGSLSEAPNRIDVVTFGCRLNTYESEVMRREAESAGLGALQGGAVIFNT
CCCCCCCCCCCCCCHHHCCCEEEEEEEEEEECCHHHHHHHHHHHHCCCCCCCCCEEEEEE
CAVTGEAVRQARQAIRKARRDNPGARIIVTGCAAQTEPEKFAAMDEVDLVLGNEEKLKAN
HHCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHCCEEEEECCCHHHCCC
SYRALPDFGVNDTEKARVNDIFSVRETAGHMVDAIEGRARAFVQVQNGCDHRCTFCIIPY
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHEEEEEECCCCCCCEEEEEEEC
GRGNSRSVPMGAVVEQVKRLAGNGYAEIVLTGVDMTSFGADLPGAPKLGRLVKTILKQVP
CCCCCCCCCHHHHHHHHHHHHCCCEEEEEEEECCHHHCCCCCCCCCHHHHHHHHHHHHCC
DVKRLRLSSIDSIEADDDLLDAIATEPRLMPHLHLSLQSGDDMILKRMKRRHLRDQSIRF
CHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHCCHHHHHH
CEDVRKLRPEIVFGADIIAGFPTETDAMFENSIKIVEECGLTHLHVFPFSPREGTPAARM
HHHHHHHCCCEEECCHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHCC
PQVRREVVKQRAARLRAAGEAAYRRHLSSLPGTRQSILIERDGLGRTEGFTLAALGTGAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEEEEECCCCC
GEIVEATITGHDGARLNAVPLAARAA
CCEEEEEEECCCCCEEEEECCHHCCC
>Mature Secondary Structure 
SVALPRSPDVDGSLSEAPNRIDVVTFGCRLNTYESEVMRREAESAGLGALQGGAVIFNT
CCCCCCCCCCCCCHHHCCCEEEEEEEEEEECCHHHHHHHHHHHHCCCCCCCCCEEEEEE
CAVTGEAVRQARQAIRKARRDNPGARIIVTGCAAQTEPEKFAAMDEVDLVLGNEEKLKAN
HHCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHCCEEEEECCCHHHCCC
SYRALPDFGVNDTEKARVNDIFSVRETAGHMVDAIEGRARAFVQVQNGCDHRCTFCIIPY
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHEEEEEECCCCCCCEEEEEEEC
GRGNSRSVPMGAVVEQVKRLAGNGYAEIVLTGVDMTSFGADLPGAPKLGRLVKTILKQVP
CCCCCCCCCHHHHHHHHHHHHCCCEEEEEEEECCHHHCCCCCCCCCHHHHHHHHHHHHCC
DVKRLRLSSIDSIEADDDLLDAIATEPRLMPHLHLSLQSGDDMILKRMKRRHLRDQSIRF
CHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHCCHHHHHH
CEDVRKLRPEIVFGADIIAGFPTETDAMFENSIKIVEECGLTHLHVFPFSPREGTPAARM
HHHHHHHCCCEEECCHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHCC
PQVRREVVKQRAARLRAAGEAAYRRHLSSLPGTRQSILIERDGLGRTEGFTLAALGTGAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEEEEECCCCC
GEIVEATITGHDGARLNAVPLAARAA
CCEEEEEEECCCCCEEEEECCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]