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The map label for this gene is yafC [C]

Identifier: 13472321

GI number: 13472321

Start: 2084486

End: 2085400

Strand: Direct

Name: yafC [C]

Synonym: mlr2579

Alternate gene names: 13472321

Gene position: 2084486-2085400 (Clockwise)

Preceding gene: 13472319

Following gene: 13472322

Centisome position: 29.63

GC content: 67.21

Gene sequence:

>915_bases
GTGGAACCGATTGACCTGCAAGGCATCGTCGCATTCGTCCAGGCCGTGGAGGCCGGCAGCTTCACCGGCGCCGGCGAGCG
GCTGCATGTGACGAAGTCGGCGATCGGCAAGTCGGTCGCCCAGTTGGAGCAGCGGCTCGGCGTTCGCCTGCTCAACCGCA
CCACCCGCAGCCTCAGGCCGACCAGCGAAGGCGTGAGCTACTATGAGGCCTGCGTCAGGGCGCTGGCCGAGATCGAGGCG
GCGCAGTCGCTGCTCGCCGCGCGCCGGCACGTCCCTTCCGGCCGGCTGCGTGTTGACGTTCCGCTCGCCTTTGGTCGGCG
CTGCGTCGCACCCGTCCTGTTCGAGATTTCCAGGAAATTCCCCGAACTCACGGTCGAAATCTCTTTCAACGACCGCCGCG
TCGACCTGATCGAGGAAGGCATCGATCTCGCCATCCGCATGGGAGAACTGGACGACAGCCTGTCGCTCGCGGCCAGACGC
ATCTACGCGCAACGCTCGGCCATCTGCGCCGCTCCCGCCTATCTCGAGGAGCACGGCAGGCCGCGATCGGTCGAGGATCT
CGCCCATCACAGCGTCATCGGCTACGGCCGCGAGGGCGTCGTCAGCCCCCGAGTGATCAGACATGGCGACGGCCGCCAGA
CGACCTTCGCCCCCAAGGCGAGGCTTGTCCTCGGCCATGGCGAACCGATGCTCGACGCCGCCCTTGCCGGCTGCGGCATT
GCCTTCCTGCCGACCTGGCTGGCAGCCGACAGCCTCAGGCATGGCGACCTCGAAATGGTCCTGTCGGACTGTGAGGTGGA
AAACATCGCCGTGCACGCCGTCTGGCCGGTGACGCGCGCGCTCACGCCAAAAGTGCGTGTTGTCGTCGACGCGCTCGTCG
AACACTTTTCGGCGCCGCCTTGGGACGAGGCCTGA

Upstream 100 bases:

>100_bases
GTCCGCGAGAGATTTATGCTTTTCGACTATGGAAAATAGAGCTCCCATGCGGCATATTCCACGACTGATTGAGGACAAAA
ATTCGCCAATTGGAATCTCC

Downstream 100 bases:

>100_bases
AGACACACGCCGTAGTCTAAGATGCCTAATATATGTCGCCCAAAAGTGGTCACGGTTTTGGTATGACGACATGCATCAAC
GCAATGCATGTCGCACAAAA

Product: transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MEPIDLQGIVAFVQAVEAGSFTGAGERLHVTKSAIGKSVAQLEQRLGVRLLNRTTRSLRPTSEGVSYYEACVRALAEIEA
AQSLLAARRHVPSGRLRVDVPLAFGRRCVAPVLFEISRKFPELTVEISFNDRRVDLIEEGIDLAIRMGELDDSLSLAARR
IYAQRSAICAAPAYLEEHGRPRSVEDLAHHSVIGYGREGVVSPRVIRHGDGRQTTFAPKARLVLGHGEPMLDAALAGCGI
AFLPTWLAADSLRHGDLEMVLSDCEVENIAVHAVWPVTRALTPKVRVVVDALVEHFSAPPWDEA

Sequences:

>Translated_304_residues
MEPIDLQGIVAFVQAVEAGSFTGAGERLHVTKSAIGKSVAQLEQRLGVRLLNRTTRSLRPTSEGVSYYEACVRALAEIEA
AQSLLAARRHVPSGRLRVDVPLAFGRRCVAPVLFEISRKFPELTVEISFNDRRVDLIEEGIDLAIRMGELDDSLSLAARR
IYAQRSAICAAPAYLEEHGRPRSVEDLAHHSVIGYGREGVVSPRVIRHGDGRQTTFAPKARLVLGHGEPMLDAALAGCGI
AFLPTWLAADSLRHGDLEMVLSDCEVENIAVHAVWPVTRALTPKVRVVVDALVEHFSAPPWDEA
>Mature_304_residues
MEPIDLQGIVAFVQAVEAGSFTGAGERLHVTKSAIGKSVAQLEQRLGVRLLNRTTRSLRPTSEGVSYYEACVRALAEIEA
AQSLLAARRHVPSGRLRVDVPLAFGRRCVAPVLFEISRKFPELTVEISFNDRRVDLIEEGIDLAIRMGELDDSLSLAARR
IYAQRSAICAAPAYLEEHGRPRSVEDLAHHSVIGYGREGVVSPRVIRHGDGRQTTFAPKARLVLGHGEPMLDAALAGCGI
AFLPTWLAADSLRHGDLEMVLSDCEVENIAVHAVWPVTRALTPKVRVVVDALVEHFSAPPWDEA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=290, Percent_Identity=33.1034482758621, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1789639, Length=296, Percent_Identity=32.0945945945946, Blast_Score=158, Evalue=5e-40,
Organism=Escherichia coli, GI145693193, Length=288, Percent_Identity=29.8611111111111, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI87081978, Length=298, Percent_Identity=32.5503355704698, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1789440, Length=296, Percent_Identity=30.7432432432432, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1787128, Length=289, Percent_Identity=27.3356401384083, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1787589, Length=295, Percent_Identity=27.7966101694915, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1789173, Length=278, Percent_Identity=26.2589928057554, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI157672245, Length=149, Percent_Identity=28.8590604026846, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788706, Length=190, Percent_Identity=26.8421052631579, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1787601, Length=152, Percent_Identity=26.9736842105263, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33188; Mature: 33188

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPIDLQGIVAFVQAVEAGSFTGAGERLHVTKSAIGKSVAQLEQRLGVRLLNRTTRSLRP
CCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TSEGVSYYEACVRALAEIEAAQSLLAARRHVPSGRLRVDVPLAFGRRCVAPVLFEISRKF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECHHHCHHHHHHHHHHHHHCC
PELTVEISFNDRRVDLIEEGIDLAIRMGELDDSLSLAARRIYAQRSAICAAPAYLEEHGR
CCEEEEEEECCCCHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCHHHHHHCCC
PRSVEDLAHHSVIGYGREGVVSPRVIRHGDGRQTTFAPKARLVLGHGEPMLDAALAGCGI
CCCHHHHHHHHHHCCCCCCCCCCHHEECCCCCCCEECCCEEEEEECCCHHHHHHHHHCCH
AFLPTWLAADSLRHGDLEMVLSDCEVENIAVHAVWPVTRALTPKVRVVVDALVEHFSAPP
HHHHHHHHHHCCCCCCHHHHHHHCCCCCEEEEEEHHHHHHCCCHHHHHHHHHHHHCCCCC
WDEA
CCCC
>Mature Secondary Structure
MEPIDLQGIVAFVQAVEAGSFTGAGERLHVTKSAIGKSVAQLEQRLGVRLLNRTTRSLRP
CCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TSEGVSYYEACVRALAEIEAAQSLLAARRHVPSGRLRVDVPLAFGRRCVAPVLFEISRKF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECHHHCHHHHHHHHHHHHHCC
PELTVEISFNDRRVDLIEEGIDLAIRMGELDDSLSLAARRIYAQRSAICAAPAYLEEHGR
CCEEEEEEECCCCHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCHHHHHHCCC
PRSVEDLAHHSVIGYGREGVVSPRVIRHGDGRQTTFAPKARLVLGHGEPMLDAALAGCGI
CCCHHHHHHHHHHCCCCCCCCCCHHEECCCCCCCEECCCEEEEEECCCHHHHHHHHHCCH
AFLPTWLAADSLRHGDLEMVLSDCEVENIAVHAVWPVTRALTPKVRVVVDALVEHFSAPP
HHHHHHHHHHCCCCCCHHHHHHHCCCCCEEEEEEHHHHHHCCCHHHHHHHHHHHHCCCCC
WDEA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]