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The map label for this gene is ytfL [C]

Identifier: 13472322

GI number: 13472322

Start: 2085628

End: 2086938

Strand: Direct

Name: ytfL [C]

Synonym: mlr2581

Alternate gene names: 13472322

Gene position: 2085628-2086938 (Clockwise)

Preceding gene: 13472321

Following gene: 13472327

Centisome position: 29.64

GC content: 66.59

Gene sequence:

>1311_bases
ATGCTATACGTCGAAATCGCTATCGTGGTCGTCCTCATCTGCGTGAACGGCCTTCTGGCAATGTCCGAACTCGCCATCGT
TTCATCGCGCCCGGCGCGGCTCAAGGCGATGATCGACCGTGGCGTCAACGGCGCCGGCCGGGCGCTGGATCTTGGCTCTA
ATCCCGGCAAGTTCCTGTCCTCGGTGCAGATCGGCATCACGCTGGTCGGCGTGCTTTCCGGCGCCTTCTCCGGCGCCACG
CTGGGTGACCGGCTGTCCGTGTTCCTGGCCACGACGGGCATGCGCGAAAGCGTCGCCGATCCGCTCGGCGTCGGCATCGT
CGTTGCCATCATCACCTATTTCTCGCTGATCGTCGGCGAACTCGTGCCCAAGCAGATCGCGCTGCGCGACCCCGAGCGCG
TCGCCGCCCGTGCGGCGCCGGCCATGACCATCCTCGCCACCATCTCGGCACCCCTGGTGTTCCTGCTCGACATTTCCGGC
CGCGCCATATTGTGGCTGCTTGGCCAGCGCGGCGAAAGCGAGGAGAAGGTCACAGACGAGGAGATCAAGATGCTGGTCGC
CGAGGCCGAGCATCACGGCACCATCGAATCCGACGAGCGGCGCATGATCGCCGGCGTCATGCGGCTTGGCGACCGCGCCG
TACGCGCGGTGATGACGCCGCGCACCGAGGTCGACTGGATCAACCTGCAGTCCGACGACACGACGATCCGCAAGCTCCTG
ATGGACACCCAGCATTCGCGCCTGCCGGCGGGCGACGGCGGCGTCGATGTCATGGTCGGCGTCGTCCAGACGCGCGACGT
GCTGGCCGCGATCCTTGCCGGCCGCACGCTGGACCCGCGCAAGCACGTGCGCGCCGCGCCCATCGTCTACGACCAGGCCG
ACGCGCTCGACGTGCTGCACAAACTCAAGGAATCCGACGTGCCGATGGCGCTGGTGCATGACGAATACGGCCATTTCGAA
GGCATCGTCACGCCGGCCGATATTCTCGAAGCCATCACCGGCGTGTTCCGCGCGGACCTCGATGCCGGCGACGAGGAAAA
CGCCGTCAAGCGCGAGGACGGCTCATGGCTGCTCGCCGGCTATATGCAGGCCGACGAGATGGCCGAGATTCTGGGCTTCG
ACCTGCCCGAAAACCGCGACTACGAAACCGTCGCCGGCTATGTCCTGTCGCATATGCACCATCTGCCGGCGACCGGCGAA
TGCGTCGACGCGCAGGGATGGCGCTTCGAGGTGGTCGACCTCGACGGCCGCCGCATCGACAAGCTGATCGCCACCCGCTT
GCCCGGCACCCACCGCGAGGCGGTGCGCTGA

Upstream 100 bases:

>100_bases
GCATCAACACAAAGACTGAAAACGCGACGCGTGTAATCCATTTACGCGCAACGCGCTTTCACTATTTTCGAGCGGCCCGC
CGCAATGCTATTGAGCCCTC

Downstream 100 bases:

>100_bases
TTGTTTGAATGTCAGCTTCAGGCCTTGGCGGTCATTGGCGGTTGGCCGGTGGATTGCGTGGCAGCTACCGCTCCGTGAAC
GCGCGCGCGAAGGAATCGAG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MLYVEIAIVVVLICVNGLLAMSELAIVSSRPARLKAMIDRGVNGAGRALDLGSNPGKFLSSVQIGITLVGVLSGAFSGAT
LGDRLSVFLATTGMRESVADPLGVGIVVAIITYFSLIVGELVPKQIALRDPERVAARAAPAMTILATISAPLVFLLDISG
RAILWLLGQRGESEEKVTDEEIKMLVAEAEHHGTIESDERRMIAGVMRLGDRAVRAVMTPRTEVDWINLQSDDTTIRKLL
MDTQHSRLPAGDGGVDVMVGVVQTRDVLAAILAGRTLDPRKHVRAAPIVYDQADALDVLHKLKESDVPMALVHDEYGHFE
GIVTPADILEAITGVFRADLDAGDEENAVKREDGSWLLAGYMQADEMAEILGFDLPENRDYETVAGYVLSHMHHLPATGE
CVDAQGWRFEVVDLDGRRIDKLIATRLPGTHREAVR

Sequences:

>Translated_436_residues
MLYVEIAIVVVLICVNGLLAMSELAIVSSRPARLKAMIDRGVNGAGRALDLGSNPGKFLSSVQIGITLVGVLSGAFSGAT
LGDRLSVFLATTGMRESVADPLGVGIVVAIITYFSLIVGELVPKQIALRDPERVAARAAPAMTILATISAPLVFLLDISG
RAILWLLGQRGESEEKVTDEEIKMLVAEAEHHGTIESDERRMIAGVMRLGDRAVRAVMTPRTEVDWINLQSDDTTIRKLL
MDTQHSRLPAGDGGVDVMVGVVQTRDVLAAILAGRTLDPRKHVRAAPIVYDQADALDVLHKLKESDVPMALVHDEYGHFE
GIVTPADILEAITGVFRADLDAGDEENAVKREDGSWLLAGYMQADEMAEILGFDLPENRDYETVAGYVLSHMHHLPATGE
CVDAQGWRFEVVDLDGRRIDKLIATRLPGTHREAVR
>Mature_436_residues
MLYVEIAIVVVLICVNGLLAMSELAIVSSRPARLKAMIDRGVNGAGRALDLGSNPGKFLSSVQIGITLVGVLSGAFSGAT
LGDRLSVFLATTGMRESVADPLGVGIVVAIITYFSLIVGELVPKQIALRDPERVAARAAPAMTILATISAPLVFLLDISG
RAILWLLGQRGESEEKVTDEEIKMLVAEAEHHGTIESDERRMIAGVMRLGDRAVRAVMTPRTEVDWINLQSDDTTIRKLL
MDTQHSRLPAGDGGVDVMVGVVQTRDVLAAILAGRTLDPRKHVRAAPIVYDQADALDVLHKLKESDVPMALVHDEYGHFE
GIVTPADILEAITGVFRADLDAGDEENAVKREDGSWLLAGYMQADEMAEILGFDLPENRDYETVAGYVLSHMHHLPATGE
CVDAQGWRFEVVDLDGRRIDKLIATRLPGTHREAVR

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=376, Percent_Identity=24.2021276595745, Blast_Score=153, Evalue=4e-37,
Organism=Escherichia coli, GI1790664, Length=426, Percent_Identity=28.6384976525822, Blast_Score=206, Evalue=3e-54,
Organism=Escherichia coli, GI87082033, Length=266, Percent_Identity=28.9473684210526, Blast_Score=131, Evalue=8e-32,
Organism=Escherichia coli, GI145693175, Length=406, Percent_Identity=25.8620689655172, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1788119, Length=274, Percent_Identity=29.9270072992701, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1786879, Length=257, Percent_Identity=29.1828793774319, Blast_Score=95, Evalue=8e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 47203; Mature: 47203

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYVEIAIVVVLICVNGLLAMSELAIVSSRPARLKAMIDRGVNGAGRALDLGSNPGKFLS
CEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCEEECCCCCHHHHH
SVQIGITLVGVLSGAFSGATLGDRLSVFLATTGMRESVADPLGVGIVVAIITYFSLIVGE
HHHHHHHHHHHHHCCCCCCCCHHHHEEEEEECCCHHHHCCHHHHHHHHHHHHHHHHHHHH
LVPKQIALRDPERVAARAAPAMTILATISAPLVFLLDISGRAILWLLGQRGESEEKVTDE
HHHHHHHCCCHHHHHHHHCHHHHHHHHHHCCEEEEEECCCCEEEEEECCCCCCCHHCCHH
EIKMLVAEAEHHGTIESDERRMIAGVMRLGDRAVRAVMTPRTEVDWINLQSDDTTIRKLL
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHH
MDTQHSRLPAGDGGVDVMVGVVQTRDVLAAILAGRTLDPRKHVRAAPIVYDQADALDVLH
HHCCCCCCCCCCCCHHHEEEHHHHHHHHHHHHHCCCCCHHHHCCCCCEEECCHHHHHHHH
KLKESDVPMALVHDEYGHFEGIVTPADILEAITGVFRADLDAGDEENAVKREDGSWLLAG
HHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEE
YMQADEMAEILGFDLPENRDYETVAGYVLSHMHHLPATGECVDAQGWRFEVVDLDGRRID
HHCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEECCCCCEEEEEECCCHHHH
KLIATRLPGTHREAVR
HHHHHCCCCCHHHHCC
>Mature Secondary Structure
MLYVEIAIVVVLICVNGLLAMSELAIVSSRPARLKAMIDRGVNGAGRALDLGSNPGKFLS
CEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCEEECCCCCHHHHH
SVQIGITLVGVLSGAFSGATLGDRLSVFLATTGMRESVADPLGVGIVVAIITYFSLIVGE
HHHHHHHHHHHHHCCCCCCCCHHHHEEEEEECCCHHHHCCHHHHHHHHHHHHHHHHHHHH
LVPKQIALRDPERVAARAAPAMTILATISAPLVFLLDISGRAILWLLGQRGESEEKVTDE
HHHHHHHCCCHHHHHHHHCHHHHHHHHHHCCEEEEEECCCCEEEEEECCCCCCCHHCCHH
EIKMLVAEAEHHGTIESDERRMIAGVMRLGDRAVRAVMTPRTEVDWINLQSDDTTIRKLL
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHH
MDTQHSRLPAGDGGVDVMVGVVQTRDVLAAILAGRTLDPRKHVRAAPIVYDQADALDVLH
HHCCCCCCCCCCCCHHHEEEHHHHHHHHHHHHHCCCCCHHHHCCCCCEEECCHHHHHHHH
KLKESDVPMALVHDEYGHFEGIVTPADILEAITGVFRADLDAGDEENAVKREDGSWLLAG
HHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEE
YMQADEMAEILGFDLPENRDYETVAGYVLSHMHHLPATGECVDAQGWRFEVVDLDGRRID
HHCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEECCCCCEEEEEECCCHHHH
KLIATRLPGTHREAVR
HHHHHCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]