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The map label for this gene is zntR [H]

Identifier: 13472246

GI number: 13472246

Start: 2012745

End: 2013164

Strand: Direct

Name: zntR [H]

Synonym: mlr2476

Alternate gene names: 13472246

Gene position: 2012745-2013164 (Clockwise)

Preceding gene: 13472244

Following gene: 13472247

Centisome position: 28.61

GC content: 65.0

Gene sequence:

>420_bases
ATGTTTTCGATCGGTGATCTCTCCCGCCGCACCGGGGTCAAGGTGCCGACCATCCGCTATTACGAGCAGATGGGCCTGGT
CGCGGCGCCCGAGCGCTCGGAAGGCAACCAGCGCCGCTATTCCAGGCAAGAGCTGGAACGGCTGGCCTTCATCCGCCACG
CCCGCGACCTTGGCTTTGCCGTCGAGGACATCCGCGCCCTGATCGATCTCAGCGGCCATCCCGAGCAGCCCTGCAGCCAT
GCCGACCAGATCGCGCAGGAGCAACTGATTTCCGTGCGCGAAAAAATCGCCCAGCTGAAGCGGCTGGAAACCGAGCTGGA
ACGCATCGCTTCCTGCCGCGACGGCAAGACGGTCGGCGACTGCTATGTCATCCGCGCGCTGTCCGACCACGCGCTGTGTG
CGGACGAGCACGTCCGATAG

Upstream 100 bases:

>100_bases
CTGCTTCCTGACCCGCGCGGCGTGCCGCTGCACGGGTCTTGAACCCTGATGTCAGGCACTGTAATTGCTCTAGTCACTAG
AGCTTCAAGAGGCAAAATGC

Downstream 100 bases:

>100_bases
CGAAATCCGGTCCGGCGCGGATCTCGGCTTGGGCGCGTGCCGCTCGTAAGACCAGGAGCAGACATGGCGAGCACTGTCAG
CGATTTCGGCTTGAGCTGCG

Product: transcriptional regulator

Products: NA

Alternate protein names: Zn(II)-responsive regulator of zntA [H]

Number of amino acids: Translated: 139; Mature: 139

Protein sequence:

>139_residues
MFSIGDLSRRTGVKVPTIRYYEQMGLVAAPERSEGNQRRYSRQELERLAFIRHARDLGFAVEDIRALIDLSGHPEQPCSH
ADQIAQEQLISVREKIAQLKRLETELERIASCRDGKTVGDCYVIRALSDHALCADEHVR

Sequences:

>Translated_139_residues
MFSIGDLSRRTGVKVPTIRYYEQMGLVAAPERSEGNQRRYSRQELERLAFIRHARDLGFAVEDIRALIDLSGHPEQPCSH
ADQIAQEQLISVREKIAQLKRLETELERIASCRDGKTVGDCYVIRALSDHALCADEHVR
>Mature_139_residues
MFSIGDLSRRTGVKVPTIRYYEQMGLVAAPERSEGNQRRYSRQELERLAFIRHARDLGFAVEDIRALIDLSGHPEQPCSH
ADQIAQEQLISVREKIAQLKRLETELERIASCRDGKTVGDCYVIRALSDHALCADEHVR

Specific function: Zinc-responsive transcriptional regulator of zntA [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789687, Length=134, Percent_Identity=38.0597014925373, Blast_Score=90, Evalue=6e-20,
Organism=Escherichia coli, GI1786695, Length=127, Percent_Identity=31.496062992126, Blast_Score=78, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358
- InterPro:   IPR011788 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 15847; Mature: 15847

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSIGDLSRRTGVKVPTIRYYEQMGLVAAPERSEGNQRRYSRQELERLAFIRHARDLGFA
CCCCCCCHHHCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VEDIRALIDLSGHPEQPCSHADQIAQEQLISVREKIAQLKRLETELERIASCRDGKTVGD
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
CYVIRALSDHALCADEHVR
HHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MFSIGDLSRRTGVKVPTIRYYEQMGLVAAPERSEGNQRRYSRQELERLAFIRHARDLGFA
CCCCCCCHHHCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VEDIRALIDLSGHPEQPCSHADQIAQEQLISVREKIAQLKRLETELERIASCRDGKTVGD
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
CYVIRALSDHALCADEHVR
HHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]