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The map label for this gene is ykoU [H]

Identifier: 13471944

GI number: 13471944

Start: 1697517

End: 1700018

Strand: Reverse

Name: ykoU [H]

Synonym: mll2077

Alternate gene names: 13471944

Gene position: 1700018-1697517 (Counterclockwise)

Preceding gene: 13471945

Following gene: 13471943

Centisome position: 24.16

GC content: 65.71

Gene sequence:

>2502_bases
ATGCCTGCTCCCGCCAAACTCAAGACCTATCGCGCCAAGCGCGAATTCTCCAAAACGCCGGAACCGGCCGGCGGGCTGAT
CAGCGGCGACGGCAACCGCTTTGTCGTCCACAAGCACCACGCGACGGCGGACCACTACGATCTGCGCCTGCAGGTCGGCG
ACGTGTTGAAGAGCTGGGCAGTGCCGCGCGGGCCCTCGCTCAATCCAGCCGACAAGAGGCTGGCGGTCGAGACCGAGGAC
CATCCGCTCGAATATATCGATTTCGAGGGCGTCATTCCCGAGGGTGAATATGGCGGCGGGCCGATGATCGTCTGGGACAC
CGGCACCTGGGCGCCGATGGACGATGTCGAGAAGAGCCTGCGCACCGGCGCTTTCAAGTTTCGCCTCGCCGGAGAAAAGC
TCAATGGCGGCTGGATGCTGACCCGCCTGAAGCCCAAGCCTGGCGAGGACGAGAACAAGAAGAACTGGCTGCTGTTCAAG
GAGCGCGACCTCGCCGCCGACACGGCGCTGGACATCCTCGAAGCGCGGCCGGAAAGCGTGAAGTCCGGATTGCTTATCGA
GGAACTGGCGGCCGCCGCGAAACCGGCGGCCAGGTCCGCGCCAAAGCCGGGTTCCCTAAAGCCCGGCGAACTGCCGGGCG
CGGTGAAGGCGCCGGCGCTCAGCCGCATCGAGCCGCAGCTGGCAACGCAGGCGCTGAGGCCGCCGGGCGGCGAAGGCCCC
GCCGAGAACACCAACGAACTCTGGCTGCACGAGATCAAATTCGATGGCTACCGCACCATGGCGCATCTGTCCGACGGGCA
GGTGCGGCTGATCACCCGCGGCGGCATCGACTGGACGAAGCGCTATGGCGACCTGCCGCATGCCTTCGCCAAACTGCCCT
GCCGCGAGGCGATCATCGACGGCGAGATCGTCGTGCTCGACGCCAAGGGCATCAGCCGCTTCGCGCTGCTGCAGGATGCG
CTGGCCGAGGGCGCCGGCAGCAAGCTGCATTTCTATGCCTTCGACCTCCTGCATCTCGACGGCTGGGATTTGCTGAAGGC
ACCGCTGATCCGGCGCAAGGCGCTGTTGGCCGAGCTGCTTGGCGGGCTCGGGGCGAATTCCGCCATCCAGTTCTCCGACC
ATGTCGAGGGCTCAGGGCAGGGGCTGTACGACCAGGCGACGGAGCTCGGGCTCGAAGGCGTCATCTCCAAGCGCGCCAGC
GCGATCTACCAGAGCGGCCGCACCAAGAGCTGGACCAAGTGCAAGGCGCTGCAGAAGGACGATTTCGTCATCGCGGGTTA
CACGATTTCGGACGCGGCGGAAGGGCTGGCGGCACTCGGCATGGCCGAGTGGGAGGAAGGCGAGCTGCACTATCGCGGCA
AGGTCGGCACCGGCTTCGATGCCGCGACGGCAGCCGACCTGCTCGCCCGGCTGGAGCCGCTGACATCGGGCGCCACGGCG
CCGGAAGGCGTGCCGCGCGAGATCATGCGCGAGATGCACTGGGTCAAGCCGCTGTTTTCGGCGCGCATCCATTACGCCAA
CCGCACGGCGGACAATGCGTTGCGCCATGGCGTGTTTCGCGGTCTCAGGGATGTCGGCCTGTCGACGCCGGTCTCGGCCA
AGCGCAAGCGGCTGATCTCGGAGGCGGATCTCGCCACCATCTGGGTGACCAATCCGGAGCGGCGGCTGTTCGGCAAGACG
GGTCCGACCAAACTCGACATCGCCGTCTATTACGCGCTGGTCGGCGACTTCATGCTGCCGCACATCCTTGGCCGCCCGGT
GTCGCTGGTGCGCTGCCCGACCGGCCTGCCGAAAGATTGCTTCTTCCAGCGCCACGCCTTCACCGGCATGCCGCCTTCGG
TGGTAACGTTCCAGGCGACCAATTCCGAGGGCGAGACCAAATCCTATCTCTCGGTCGAGGGCGCAAAAGGCTATCTGGCT
CTGGCGCAGTTCGGCGTCGTCGAGTTCCACACCTGGGGCACGCACCGCACCAGCCTCGACAAGCCCGATCAGATCGTCTT
CGACCTCGATCCGGGCGCGGGGATTTCCTGGCGCGAAGTGGTGGAAGCCGCCGTCCACATCAAGGGCGAGCTCGAGGGGC
TGGGGCTGGTGCCGTTCGCCAAGACGTCAGGAGGCAGCGGCATCCACATCACCGTGCCGGTGACGTCAAAGCAGAACTGG
AAGAAGCTGCACCAGGCGACCAGCGCCATCTCCACGCATCTGGCGGCGACCGCGCCCGACACATTCACCACCACCATGGG
CAAGGAAAACCGCAAGAAGCGTATCTTCATCGACTATCACCGCAACGCCCGCGGCCACACCTCCGCGGCGCCCTATTCGC
TGCGCGCCCGCACCAATTTGCCGGCTTCGACCCCGGTGAGCTGGAGCGATCTGGAGGCGATCGATGCGCCGCAGGACCTG
AACTATTCGTCGCTGCCGGGGCTGCTGGAGACGTCGGGTGATCCCTGGGCAGATATCGAGGACTTTGCCCGGGATTTGCC
TACCTATCTTTCGTCATCCTAG

Upstream 100 bases:

>100_bases
CTCGAGCTGACGCCGGCTGCCGACGATTGACAGCGTGACTGCCATCCGTTCCGGAACGCGGCGGTTGCTCCTGCTTGCCA
AGCGCTTCGGGCGCTGACCC

Downstream 100 bases:

>100_bases
GCGAAGCAAGGAGCGAAGCGACGCGTAGACCCTAGGATCCATGCCGTGACGTTGGCCTTAGAATGCAGCGGGTTCAGAAT
GGTCGCCAACTGTAGCGCCG

Product: ATP-dependent DNA ligase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 833; Mature: 832

Protein sequence:

>833_residues
MPAPAKLKTYRAKREFSKTPEPAGGLISGDGNRFVVHKHHATADHYDLRLQVGDVLKSWAVPRGPSLNPADKRLAVETED
HPLEYIDFEGVIPEGEYGGGPMIVWDTGTWAPMDDVEKSLRTGAFKFRLAGEKLNGGWMLTRLKPKPGEDENKKNWLLFK
ERDLAADTALDILEARPESVKSGLLIEELAAAAKPAARSAPKPGSLKPGELPGAVKAPALSRIEPQLATQALRPPGGEGP
AENTNELWLHEIKFDGYRTMAHLSDGQVRLITRGGIDWTKRYGDLPHAFAKLPCREAIIDGEIVVLDAKGISRFALLQDA
LAEGAGSKLHFYAFDLLHLDGWDLLKAPLIRRKALLAELLGGLGANSAIQFSDHVEGSGQGLYDQATELGLEGVISKRAS
AIYQSGRTKSWTKCKALQKDDFVIAGYTISDAAEGLAALGMAEWEEGELHYRGKVGTGFDAATAADLLARLEPLTSGATA
PEGVPREIMREMHWVKPLFSARIHYANRTADNALRHGVFRGLRDVGLSTPVSAKRKRLISEADLATIWVTNPERRLFGKT
GPTKLDIAVYYALVGDFMLPHILGRPVSLVRCPTGLPKDCFFQRHAFTGMPPSVVTFQATNSEGETKSYLSVEGAKGYLA
LAQFGVVEFHTWGTHRTSLDKPDQIVFDLDPGAGISWREVVEAAVHIKGELEGLGLVPFAKTSGGSGIHITVPVTSKQNW
KKLHQATSAISTHLAATAPDTFTTTMGKENRKKRIFIDYHRNARGHTSAAPYSLRARTNLPASTPVSWSDLEAIDAPQDL
NYSSLPGLLETSGDPWADIEDFARDLPTYLSSS

Sequences:

>Translated_833_residues
MPAPAKLKTYRAKREFSKTPEPAGGLISGDGNRFVVHKHHATADHYDLRLQVGDVLKSWAVPRGPSLNPADKRLAVETED
HPLEYIDFEGVIPEGEYGGGPMIVWDTGTWAPMDDVEKSLRTGAFKFRLAGEKLNGGWMLTRLKPKPGEDENKKNWLLFK
ERDLAADTALDILEARPESVKSGLLIEELAAAAKPAARSAPKPGSLKPGELPGAVKAPALSRIEPQLATQALRPPGGEGP
AENTNELWLHEIKFDGYRTMAHLSDGQVRLITRGGIDWTKRYGDLPHAFAKLPCREAIIDGEIVVLDAKGISRFALLQDA
LAEGAGSKLHFYAFDLLHLDGWDLLKAPLIRRKALLAELLGGLGANSAIQFSDHVEGSGQGLYDQATELGLEGVISKRAS
AIYQSGRTKSWTKCKALQKDDFVIAGYTISDAAEGLAALGMAEWEEGELHYRGKVGTGFDAATAADLLARLEPLTSGATA
PEGVPREIMREMHWVKPLFSARIHYANRTADNALRHGVFRGLRDVGLSTPVSAKRKRLISEADLATIWVTNPERRLFGKT
GPTKLDIAVYYALVGDFMLPHILGRPVSLVRCPTGLPKDCFFQRHAFTGMPPSVVTFQATNSEGETKSYLSVEGAKGYLA
LAQFGVVEFHTWGTHRTSLDKPDQIVFDLDPGAGISWREVVEAAVHIKGELEGLGLVPFAKTSGGSGIHITVPVTSKQNW
KKLHQATSAISTHLAATAPDTFTTTMGKENRKKRIFIDYHRNARGHTSAAPYSLRARTNLPASTPVSWSDLEAIDAPQDL
NYSSLPGLLETSGDPWADIEDFARDLPTYLSSS
>Mature_832_residues
PAPAKLKTYRAKREFSKTPEPAGGLISGDGNRFVVHKHHATADHYDLRLQVGDVLKSWAVPRGPSLNPADKRLAVETEDH
PLEYIDFEGVIPEGEYGGGPMIVWDTGTWAPMDDVEKSLRTGAFKFRLAGEKLNGGWMLTRLKPKPGEDENKKNWLLFKE
RDLAADTALDILEARPESVKSGLLIEELAAAAKPAARSAPKPGSLKPGELPGAVKAPALSRIEPQLATQALRPPGGEGPA
ENTNELWLHEIKFDGYRTMAHLSDGQVRLITRGGIDWTKRYGDLPHAFAKLPCREAIIDGEIVVLDAKGISRFALLQDAL
AEGAGSKLHFYAFDLLHLDGWDLLKAPLIRRKALLAELLGGLGANSAIQFSDHVEGSGQGLYDQATELGLEGVISKRASA
IYQSGRTKSWTKCKALQKDDFVIAGYTISDAAEGLAALGMAEWEEGELHYRGKVGTGFDAATAADLLARLEPLTSGATAP
EGVPREIMREMHWVKPLFSARIHYANRTADNALRHGVFRGLRDVGLSTPVSAKRKRLISEADLATIWVTNPERRLFGKTG
PTKLDIAVYYALVGDFMLPHILGRPVSLVRCPTGLPKDCFFQRHAFTGMPPSVVTFQATNSEGETKSYLSVEGAKGYLAL
AQFGVVEFHTWGTHRTSLDKPDQIVFDLDPGAGISWREVVEAAVHIKGELEGLGLVPFAKTSGGSGIHITVPVTSKQNWK
KLHQATSAISTHLAATAPDTFTTTMGKENRKKRIFIDYHRNARGHTSAAPYSLRARTNLPASTPVSWSDLEAIDAPQDLN
YSSLPGLLETSGDPWADIEDFARDLPTYLSSS

Specific function: Probably involved in the repair of DNA double-strand breaks by non-homologous-end joining (NHEJ) during spore germination [H]

COG id: COG1793

COG function: function code L; ATP-dependent DNA ligase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent DNA ligase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012310
- InterPro:   IPR014146
- InterPro:   IPR014145
- InterPro:   IPR014143 [H]

Pfam domain/function: PF01068 DNA_ligase_A_M [H]

EC number: =6.5.1.1 [H]

Molecular weight: Translated: 90747; Mature: 90616

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: PS50160 DNA_LIGASE_A3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAPAKLKTYRAKREFSKTPEPAGGLISGDGNRFVVHKHHATADHYDLRLQVGDVLKSWA
CCCCCCHHHHHHHHHHCCCCCCCCCEEECCCCEEEEEECCCCCCCEEEEEEHHHHHHHCC
VPRGPSLNPADKRLAVETEDHPLEYIDFEGVIPEGEYGGGPMIVWDTGTWAPMDDVEKSL
CCCCCCCCCHHCEEEEECCCCCCEEEECCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHH
RTGAFKFRLAGEKLNGGWMLTRLKPKPGEDENKKNWLLFKERDLAADTALDILEARPESV
HCCCEEEEEECCCCCCCEEEEEECCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCHHHH
KSGLLIEELAAAAKPAARSAPKPGSLKPGELPGAVKAPALSRIEPQLATQALRPPGGEGP
HCCHHHHHHHHHCCCHHCCCCCCCCCCCCCCCCCCCCCCHHHCCHHHHHHHCCCCCCCCC
AENTNELWLHEIKFDGYRTMAHLSDGQVRLITRGGIDWTKRYGDLPHAFAKLPCREAIID
CCCCCCEEEEEEEECCEEEEEECCCCCEEEEEECCCCHHHHCCCCCHHHHHCCHHHHEEC
GEIVVLDAKGISRFALLQDALAEGAGSKLHFYAFDLLHLDGWDLLKAPLIRRKALLAELL
CCEEEEECCCCHHHHHHHHHHHHCCCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHH
GGLGANSAIQFSDHVEGSGQGLYDQATELGLEGVISKRASAIYQSGRTKSWTKCKALQKD
HCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCC
DFVIAGYTISDAAEGLAALGMAEWEEGELHYRGKVGTGFDAATAADLLARLEPLTSGATA
CEEEEEEEHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCC
PEGVPREIMREMHWVKPLFSARIHYANRTADNALRHGVFRGLRDVGLSTPVSAKRKRLIS
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
EADLATIWVTNPERRLFGKTGPTKLDIAVYYALVGDFMLPHILGRPVSLVRCPTGLPKDC
HCCEEEEEEECCHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHH
FFQRHAFTGMPPSVVTFQATNSEGETKSYLSVEGAKGYLALAQFGVVEFHTWGTHRTSLD
HHHHHCCCCCCCCEEEEEECCCCCCCCCEEEECCCCCEEEHHHCCEEEEEECCCCCCCCC
KPDQIVFDLDPGAGISWREVVEAAVHIKGELEGLGLVPFAKTSGGSGIHITVPVTSKQNW
CCCCEEEECCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCCEEEEEEEECCCHHH
KKLHQATSAISTHLAATAPDTFTTTMGKENRKKRIFIDYHRNARGHTSAAPYSLRARTNL
HHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCEEEEEECCCCCCCCCCCCEEEEECCCC
PASTPVSWSDLEAIDAPQDLNYSSLPGLLETSGDPWADIEDFARDLPTYLSSS
CCCCCCCCCHHHHCCCCCCCCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PAPAKLKTYRAKREFSKTPEPAGGLISGDGNRFVVHKHHATADHYDLRLQVGDVLKSWA
CCCCCHHHHHHHHHHCCCCCCCCCEEECCCCEEEEEECCCCCCCEEEEEEHHHHHHHCC
VPRGPSLNPADKRLAVETEDHPLEYIDFEGVIPEGEYGGGPMIVWDTGTWAPMDDVEKSL
CCCCCCCCCHHCEEEEECCCCCCEEEECCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHH
RTGAFKFRLAGEKLNGGWMLTRLKPKPGEDENKKNWLLFKERDLAADTALDILEARPESV
HCCCEEEEEECCCCCCCEEEEEECCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCHHHH
KSGLLIEELAAAAKPAARSAPKPGSLKPGELPGAVKAPALSRIEPQLATQALRPPGGEGP
HCCHHHHHHHHHCCCHHCCCCCCCCCCCCCCCCCCCCCCHHHCCHHHHHHHCCCCCCCCC
AENTNELWLHEIKFDGYRTMAHLSDGQVRLITRGGIDWTKRYGDLPHAFAKLPCREAIID
CCCCCCEEEEEEEECCEEEEEECCCCCEEEEEECCCCHHHHCCCCCHHHHHCCHHHHEEC
GEIVVLDAKGISRFALLQDALAEGAGSKLHFYAFDLLHLDGWDLLKAPLIRRKALLAELL
CCEEEEECCCCHHHHHHHHHHHHCCCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHH
GGLGANSAIQFSDHVEGSGQGLYDQATELGLEGVISKRASAIYQSGRTKSWTKCKALQKD
HCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCC
DFVIAGYTISDAAEGLAALGMAEWEEGELHYRGKVGTGFDAATAADLLARLEPLTSGATA
CEEEEEEEHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCC
PEGVPREIMREMHWVKPLFSARIHYANRTADNALRHGVFRGLRDVGLSTPVSAKRKRLIS
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
EADLATIWVTNPERRLFGKTGPTKLDIAVYYALVGDFMLPHILGRPVSLVRCPTGLPKDC
HCCEEEEEEECCHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHH
FFQRHAFTGMPPSVVTFQATNSEGETKSYLSVEGAKGYLALAQFGVVEFHTWGTHRTSLD
HHHHHCCCCCCCCEEEEEECCCCCCCCCEEEECCCCCEEEHHHCCEEEEEECCCCCCCCC
KPDQIVFDLDPGAGISWREVVEAAVHIKGELEGLGLVPFAKTSGGSGIHITVPVTSKQNW
CCCCEEEECCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCCEEEEEEEECCCHHH
KKLHQATSAISTHLAATAPDTFTTTMGKENRKKRIFIDYHRNARGHTSAAPYSLRARTNL
HHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCEEEEEECCCCCCCCCCCCEEEEECCCC
PASTPVSWSDLEAIDAPQDLNYSSLPGLLETSGDPWADIEDFARDLPTYLSSS
CCCCCCCCCHHHHCCCCCCCCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]