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The map label for this gene is pbp [H]

Identifier: 13471886

GI number: 13471886

Start: 1643888

End: 1645444

Strand: Reverse

Name: pbp [H]

Synonym: mll2003

Alternate gene names: 13471886

Gene position: 1645444-1643888 (Counterclockwise)

Preceding gene: 13471888

Following gene: 13471884

Centisome position: 23.39

GC content: 66.35

Gene sequence:

>1557_bases
GTGCGGCTGGATCGGAACCCCTGGCATTGGCGAATCTGGGTCTGCATCGCCGTACTGGCGCTTTGGCCGCGTGCCGCGTC
GGCCGACACCATCACGCCGGAGCGCATCGCAGACGCCCTGTCGAAGCTCGACGCGCTCGCCCAAGGCGCGGTCGCGGACG
GAGGCGTGCCCGGTCTTGCCATCGCGGTGGTGCACGACGATGAGGTGATCTTCCTCAGAGGTTTCGGCCATCGCGAGGCG
GGCAAGCCTGAGGCGGTCGACGCCGACACGGTGTTCCAGATCGCCTCGCTTTCCAAGCCGGTCTCCGCCACCGTCGTGGC
GGCGCTGGTGAGCGACGGGATCGTGTCCTGGGATTCGAAGGTCGCCGACCTCGATCCCGCCTTCCGGCTGGCCGATCCCT
ATCCGACCAGCCAACTCACCGTCCGCGACCTGTTTTCGCACCGCAGCGGACTGCCCGGCACCGCCGGAGACGACCTCGAG
GACATAGGCTACGACCGCGCCGAGATCCTGCATCGCTTGCGGTTCGTGCCGCCATCGTCGAGCTTCCGTGCCGGCTACTC
CTACAGCAATTTCGGACTGACCGAGGGCGCCGTCGCGGCCGCAATGCCGACAGGCAAGTCCTGGGAGGAGGTCGCGCAGG
AGAAGCTCTACCGTCCGCTCGGCATGGCCTCGACTAGTTCCCGTCATTCGGATTTCGTCAAGCACGCCGATCGTGCCGCG
CTGCACATCAAGGTCGATGGCGCCTGGGCCGCCAAGATAGAGCGCGATCCGGATGCGCAGGCGCCCGCGGGCGGCGTCAG
TTCCACCGCGCGCGATCTCTCGCAATGGGTGCGCCTCATTCTTGGCAACGGGGTCTATGCCGGCAAGACGCTGATTGCCG
CCGATGCGCTGGATCAGACGCATGTGCCGCTGATGACGCGCGGCAAGAATCCTGTCTCCGGCGGCGAGTCCTTCTACGGC
CTCGGCTGGAATGTCGAATTCGGCCGGCATGGCCTGAGCTGGGGCCATGCCGGTGCCTTCAGCGTCGGCGCACGCACGCT
GGTGACGATCTTCCCGCAGGATAAGCTTGGCATCGTCATCATCGCCAACGCCTTCCCGACAGGCGTGCCGGAGGGATTGT
CCGACAGTTTCGCGGACCTCGTCTTCGACGGTTCGGTTCAGAAGGACTGGGTTAAGGCATGGGACGGAATCTATGCCGGA
ATGTTCGGCCCGGTAGTCGAGGCGGCCAAGGCCACCTATGCCGCGCCGCCATCTCCGGCACGGCCGGCCAGGCCGGCAAG
TGCCTATGCCGGCCGCTACGCCAACGACTTCTTCGGCGACGCGGTCGTGGCGAGTGCGGGAGACGGCCTCGTGCTCAAGG
TCGGCCCGCACGGCGCCCGGTCCTATTCCCTGGCGCATTTCGATGGCGATCTTTTCCTGACCTATCCCGACGCCGAGACG
CCGGACAGGCCAACCGGCGTGAGCTTCGTCGTCGGCCCGGACGGCAAGGCATCGGCCATGACCATTGGTTTCCTCGACGA
CAATCATCTCGGTACGTTGCGGCGTGTGGGCGATTAG

Upstream 100 bases:

>100_bases
CGATTGCGACGAAGGTGGACAGCGGGGCGGCAGGCATTGGCCTCGTTTGCGCCGGCCTGTATCATAGCCAGGTGAATAAT
GCAGGAGAGGAGGCTCGAGC

Downstream 100 bases:

>100_bases
CGGCTGACAGGGGTAACGAGCGGCGTCGGGGCACGCGTCTTGTGCCGCAGCTCATCGTTCCAGACATACTTGCCCCATGT
CGGATCGTCGCAAAGATCGA

Product: hypothetical protein

Products: NA

Alternate protein names: PBP-4 [H]

Number of amino acids: Translated: 518; Mature: 518

Protein sequence:

>518_residues
MRLDRNPWHWRIWVCIAVLALWPRAASADTITPERIADALSKLDALAQGAVADGGVPGLAIAVVHDDEVIFLRGFGHREA
GKPEAVDADTVFQIASLSKPVSATVVAALVSDGIVSWDSKVADLDPAFRLADPYPTSQLTVRDLFSHRSGLPGTAGDDLE
DIGYDRAEILHRLRFVPPSSSFRAGYSYSNFGLTEGAVAAAMPTGKSWEEVAQEKLYRPLGMASTSSRHSDFVKHADRAA
LHIKVDGAWAAKIERDPDAQAPAGGVSSTARDLSQWVRLILGNGVYAGKTLIAADALDQTHVPLMTRGKNPVSGGESFYG
LGWNVEFGRHGLSWGHAGAFSVGARTLVTIFPQDKLGIVIIANAFPTGVPEGLSDSFADLVFDGSVQKDWVKAWDGIYAG
MFGPVVEAAKATYAAPPSPARPARPASAYAGRYANDFFGDAVVASAGDGLVLKVGPHGARSYSLAHFDGDLFLTYPDAET
PDRPTGVSFVVGPDGKASAMTIGFLDDNHLGTLRRVGD

Sequences:

>Translated_518_residues
MRLDRNPWHWRIWVCIAVLALWPRAASADTITPERIADALSKLDALAQGAVADGGVPGLAIAVVHDDEVIFLRGFGHREA
GKPEAVDADTVFQIASLSKPVSATVVAALVSDGIVSWDSKVADLDPAFRLADPYPTSQLTVRDLFSHRSGLPGTAGDDLE
DIGYDRAEILHRLRFVPPSSSFRAGYSYSNFGLTEGAVAAAMPTGKSWEEVAQEKLYRPLGMASTSSRHSDFVKHADRAA
LHIKVDGAWAAKIERDPDAQAPAGGVSSTARDLSQWVRLILGNGVYAGKTLIAADALDQTHVPLMTRGKNPVSGGESFYG
LGWNVEFGRHGLSWGHAGAFSVGARTLVTIFPQDKLGIVIIANAFPTGVPEGLSDSFADLVFDGSVQKDWVKAWDGIYAG
MFGPVVEAAKATYAAPPSPARPARPASAYAGRYANDFFGDAVVASAGDGLVLKVGPHGARSYSLAHFDGDLFLTYPDAET
PDRPTGVSFVVGPDGKASAMTIGFLDDNHLGTLRRVGD
>Mature_518_residues
MRLDRNPWHWRIWVCIAVLALWPRAASADTITPERIADALSKLDALAQGAVADGGVPGLAIAVVHDDEVIFLRGFGHREA
GKPEAVDADTVFQIASLSKPVSATVVAALVSDGIVSWDSKVADLDPAFRLADPYPTSQLTVRDLFSHRSGLPGTAGDDLE
DIGYDRAEILHRLRFVPPSSSFRAGYSYSNFGLTEGAVAAAMPTGKSWEEVAQEKLYRPLGMASTSSRHSDFVKHADRAA
LHIKVDGAWAAKIERDPDAQAPAGGVSSTARDLSQWVRLILGNGVYAGKTLIAADALDQTHVPLMTRGKNPVSGGESFYG
LGWNVEFGRHGLSWGHAGAFSVGARTLVTIFPQDKLGIVIIANAFPTGVPEGLSDSFADLVFDGSVQKDWVKAWDGIYAG
MFGPVVEAAKATYAAPPSPARPARPASAYAGRYANDFFGDAVVASAGDGLVLKVGPHGARSYSLAHFDGDLFLTYPDAET
PDRPTGVSFVVGPDGKASAMTIGFLDDNHLGTLRRVGD

Specific function: Involved in cell wall biosynthesis and may also act as a sensor of external penicillins [H]

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-lactamase family [H]

Homologues:

Organism=Escherichia coli, GI1786574, Length=363, Percent_Identity=25.068870523416, Blast_Score=79, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI115533026, Length=363, Percent_Identity=24.7933884297521, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17550934, Length=316, Percent_Identity=25, Blast_Score=77, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: NA

Molecular weight: Translated: 54962; Mature: 54962

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLDRNPWHWRIWVCIAVLALWPRAASADTITPERIADALSKLDALAQGAVADGGVPGLA
CCCCCCCCEEHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEE
IAVVHDDEVIFLRGFGHREAGKPEAVDADTVFQIASLSKPVSATVVAALVSDGIVSWDSK
EEEEECCCEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCC
VADLDPAFRLADPYPTSQLTVRDLFSHRSGLPGTAGDDLEDIGYDRAEILHRLRFVPPSS
CCCCCCCCEECCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHCCCCHHHHHHHHHCCCCCC
SFRAGYSYSNFGLTEGAVAAAMPTGKSWEEVAQEKLYRPLGMASTSSRHSDFVKHADRAA
CCCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCEE
LHIKVDGAWAAKIERDPDAQAPAGGVSSTARDLSQWVRLILGNGVYAGKTLIAADALDQT
EEEEECCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCC
HVPLMTRGKNPVSGGESFYGLGWNVEFGRHGLSWGHAGAFSVGARTLVTIFPQDKLGIVI
CCCCEECCCCCCCCCCCEEEECEEEECCCCCCCCCCCCCHHCCCEEEEEEECCCCCCEEE
IANAFPTGVPEGLSDSFADLVFDGSVQKDWVKAWDGIYAGMFGPVVEAAKATYAAPPSPA
EECCCCCCCCCCCCHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
RPARPASAYAGRYANDFFGDAVVASAGDGLVLKVGPHGARSYSLAHFDGDLFLTYPDAET
CCCCCCHHHHCCCCHHHHCCCCEECCCCCEEEEECCCCCCCEEEEEECCCEEEECCCCCC
PDRPTGVSFVVGPDGKASAMTIGFLDDNHLGTLRRVGD
CCCCCCEEEEECCCCCCCEEEEEEECCCCCCHHHHCCC
>Mature Secondary Structure
MRLDRNPWHWRIWVCIAVLALWPRAASADTITPERIADALSKLDALAQGAVADGGVPGLA
CCCCCCCCEEHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEE
IAVVHDDEVIFLRGFGHREAGKPEAVDADTVFQIASLSKPVSATVVAALVSDGIVSWDSK
EEEEECCCEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCC
VADLDPAFRLADPYPTSQLTVRDLFSHRSGLPGTAGDDLEDIGYDRAEILHRLRFVPPSS
CCCCCCCCEECCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHCCCCHHHHHHHHHCCCCCC
SFRAGYSYSNFGLTEGAVAAAMPTGKSWEEVAQEKLYRPLGMASTSSRHSDFVKHADRAA
CCCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCEE
LHIKVDGAWAAKIERDPDAQAPAGGVSSTARDLSQWVRLILGNGVYAGKTLIAADALDQT
EEEEECCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCC
HVPLMTRGKNPVSGGESFYGLGWNVEFGRHGLSWGHAGAFSVGARTLVTIFPQDKLGIVI
CCCCEECCCCCCCCCCCEEEECEEEECCCCCCCCCCCCCHHCCCEEEEEEECCCCCCEEE
IANAFPTGVPEGLSDSFADLVFDGSVQKDWVKAWDGIYAGMFGPVVEAAKATYAAPPSPA
EECCCCCCCCCCCCHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
RPARPASAYAGRYANDFFGDAVVASAGDGLVLKVGPHGARSYSLAHFDGDLFLTYPDAET
CCCCCCHHHHCCCCHHHHCCCCEECCCCCEEEEECCCCCCCEEEEEECCCEEEECCCCCC
PDRPTGVSFVVGPDGKASAMTIGFLDDNHLGTLRRVGD
CCCCCCEEEEECCCCCCCEEEEEEECCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8440253 [H]