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The map label for this gene is glmS

Identifier: 13470983

GI number: 13470983

Start: 663270

End: 665093

Strand: Reverse

Name: glmS

Synonym: mll0833

Alternate gene names: 13470983

Gene position: 665093-663270 (Counterclockwise)

Preceding gene: 13470986

Following gene: 13470982

Centisome position: 9.45

GC content: 63.6

Gene sequence:

>1824_bases
ATGTGCGGTATCGTTGGAATCGTCGGCCACTCGCAGGTTGCGCCGCTCATCGTCGATGCGCTGAAGCGGCTTGAGTATCG
CGGTTATGACTCGGCCGGCGTCGCCACCATCGAGCATGGCGAGCTCGCCCGCCGTCGCGCCGAAGGCAAATTGATCAACC
TCGAGCGCCGGCTCAAGGAGGAGCCGCTCGACGGCACGATCGGCATCGGCCACACACGCTGGGCCACCCATGGCGTGCCC
AACGAGACCAATGCGCATCCGCATTTTTCCGACGGCGTCGCCATCGTCCACAACGGCATCATCGAGAACTTTGCCGAGCT
GCGCGACGAGCTGGTCCGCGACGGCTATGCCTTCTCCTCGCAGACCGATACAGAGGTCGTGGCGCATCTGGTGGCGCGCG
AGTTGGCCAAGGGGCTGAAGCCGGTCGAGGCCGCGCATCAGGCGCTGAAGCGGCTGGAAGGCGCCTTTGCGCTGGCCATC
ATGTTCAAGGGCGACGAGGACCTGATCGTCGGCGCCCGCAACGGCCCGCCACTGGCCGTCGGCCATGGCGATGGCGAGAT
GTTCTTGGGCTCGGACGCCATCGCGCTGGCGCCATTCACCAATTCGATCACCTATCTCGAGGACGGCGACTGGGCGGTGG
TGCGCCGCGACAGCGTCGCCATCTTCGACATCGACGGCAAAAAGGTCGAGCGCAAGCGCCAGCAATCGCTGTCGACCTCC
TTCATGGTCGACAAGGGCAACCGCCGGCATTTCATGGAGAAGGAAATCCATGAACAGCCCGAGGTGATCTCGCACACGCT
GGCGCATTATGTCGATTTCGTCTCCGGCGTTTCGAAGCCGCTCGACCTGCCGTTCGACTTCGCCAAGATCGGCCGGCTGG
CGATTTCGGCTTGCGGCACCGCCTATCTCGCCGGCCTGATCGGCAAATACTGGTTCGAGCGCTATGCGCGGCTGCCGGTC
GACATCGATGTCGCCTCGGAGTTCCGCTACCGCGAAATGCCGCTGTCGGCCAACGATGCCGCCTTCTTCATCTCGCAGTC
GGGCGAGACCGCCGACACGCTGGCCTCGCTGCGTTATTGCCGCAAGGCCGGCATGAAGATCGGCGCCGTCGTCAATGTGC
GCGAATCGACCATGGCGCGCGAATCCGACGTCGTGCTGCCGACACTCGCCGGCCCCGAGATCGGCGTCGCCTCGACCAAG
GCTTTCACTTGCCAGCTGTCGGTGCTGGCCTCGCTTGCGGTGCGCGCCGGCGTGGCGCGCGGGGTGATTTCGCAGGAGCA
GGAAAAGACCCTGGTGCGCGCGCTTTCGGAAGCGCCGCGCTATGCCAACCAGGTGCTCAAGCTCGAAGAGCAGATCGAGC
GGATCGCGCGCGAACTGTCGCGCTACAAGGACGTGCTCTATCTCGGCCGCGACACCAATTTCCCGCTGGCCATGGAAGGC
GCGCTGAAACTCAAGGAAATCTCCTATATCCACGCCGAGGGCTATGCGGCGGGCGAATTGAAGCATGGGCCGATCGCGCT
GATCGACGAGAACATGCCGGTCATTGTCATTGCGCCGCATGACCGCATTTTCGAGAAGACCGTGTCGAACATGCAGGAAG
TGGCGGCGCGTGGCGGCAAGATCATCCTGATCACCGACAGCAAAGGGGCGGCGCAGGTGAGCGTCAAGACGATGGAGACG
ATCATCCTGCCGGACGTGCCGGAAATCATCTCGCCGATCATCTATGCGCTGCCGATCCAGATGCTGGCCTATTTCGCCGC
CGTGTTCATGGGCACCGATGTCGACCAGCCGCGCAATCTGGCGAAATCCGTGACGGTGGAATAG

Upstream 100 bases:

>100_bases
AAGCGTCCGTTACACCGGACGAAATGCAATGTGACTTTCACGGCAGGCCGGCCATCCCTAAATAGCGCTGGTTTTCCATG
GGGAATCGGGGACTGTCTGC

Downstream 100 bases:

>100_bases
GGGGCCCTAACAGGCGCTCTTTAAAAACTTCGCAGTTCCAAACGGCGTCCCGGTTCACTAATGTTGCGCTGCAACCCGCG
CCCGGTGAACCATGTCCGAT

Product: glucosamine--fructose-6-phosphate aminotransferase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase

Number of amino acids: Translated: 607; Mature: 607

Protein sequence:

>607_residues
MCGIVGIVGHSQVAPLIVDALKRLEYRGYDSAGVATIEHGELARRRAEGKLINLERRLKEEPLDGTIGIGHTRWATHGVP
NETNAHPHFSDGVAIVHNGIIENFAELRDELVRDGYAFSSQTDTEVVAHLVARELAKGLKPVEAAHQALKRLEGAFALAI
MFKGDEDLIVGARNGPPLAVGHGDGEMFLGSDAIALAPFTNSITYLEDGDWAVVRRDSVAIFDIDGKKVERKRQQSLSTS
FMVDKGNRRHFMEKEIHEQPEVISHTLAHYVDFVSGVSKPLDLPFDFAKIGRLAISACGTAYLAGLIGKYWFERYARLPV
DIDVASEFRYREMPLSANDAAFFISQSGETADTLASLRYCRKAGMKIGAVVNVRESTMARESDVVLPTLAGPEIGVASTK
AFTCQLSVLASLAVRAGVARGVISQEQEKTLVRALSEAPRYANQVLKLEEQIERIARELSRYKDVLYLGRDTNFPLAMEG
ALKLKEISYIHAEGYAAGELKHGPIALIDENMPVIVIAPHDRIFEKTVSNMQEVAARGGKIILITDSKGAAQVSVKTMET
IILPDVPEIISPIIYALPIQMLAYFAAVFMGTDVDQPRNLAKSVTVE

Sequences:

>Translated_607_residues
MCGIVGIVGHSQVAPLIVDALKRLEYRGYDSAGVATIEHGELARRRAEGKLINLERRLKEEPLDGTIGIGHTRWATHGVP
NETNAHPHFSDGVAIVHNGIIENFAELRDELVRDGYAFSSQTDTEVVAHLVARELAKGLKPVEAAHQALKRLEGAFALAI
MFKGDEDLIVGARNGPPLAVGHGDGEMFLGSDAIALAPFTNSITYLEDGDWAVVRRDSVAIFDIDGKKVERKRQQSLSTS
FMVDKGNRRHFMEKEIHEQPEVISHTLAHYVDFVSGVSKPLDLPFDFAKIGRLAISACGTAYLAGLIGKYWFERYARLPV
DIDVASEFRYREMPLSANDAAFFISQSGETADTLASLRYCRKAGMKIGAVVNVRESTMARESDVVLPTLAGPEIGVASTK
AFTCQLSVLASLAVRAGVARGVISQEQEKTLVRALSEAPRYANQVLKLEEQIERIARELSRYKDVLYLGRDTNFPLAMEG
ALKLKEISYIHAEGYAAGELKHGPIALIDENMPVIVIAPHDRIFEKTVSNMQEVAARGGKIILITDSKGAAQVSVKTMET
IILPDVPEIISPIIYALPIQMLAYFAAVFMGTDVDQPRNLAKSVTVE
>Mature_607_residues
MCGIVGIVGHSQVAPLIVDALKRLEYRGYDSAGVATIEHGELARRRAEGKLINLERRLKEEPLDGTIGIGHTRWATHGVP
NETNAHPHFSDGVAIVHNGIIENFAELRDELVRDGYAFSSQTDTEVVAHLVARELAKGLKPVEAAHQALKRLEGAFALAI
MFKGDEDLIVGARNGPPLAVGHGDGEMFLGSDAIALAPFTNSITYLEDGDWAVVRRDSVAIFDIDGKKVERKRQQSLSTS
FMVDKGNRRHFMEKEIHEQPEVISHTLAHYVDFVSGVSKPLDLPFDFAKIGRLAISACGTAYLAGLIGKYWFERYARLPV
DIDVASEFRYREMPLSANDAAFFISQSGETADTLASLRYCRKAGMKIGAVVNVRESTMARESDVVLPTLAGPEIGVASTK
AFTCQLSVLASLAVRAGVARGVISQEQEKTLVRALSEAPRYANQVLKLEEQIERIARELSRYKDVLYLGRDTNFPLAMEG
ALKLKEISYIHAEGYAAGELKHGPIALIDENMPVIVIAPHDRIFEKTVSNMQEVAARGGKIILITDSKGAAQVSVKTMET
IILPDVPEIISPIIYALPIQMLAYFAAVFMGTDVDQPRNLAKSVTVE

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains

Homologues:

Organism=Homo sapiens, GI4826742, Length=695, Percent_Identity=36.4028776978417, Blast_Score=392, Evalue=1e-109,
Organism=Homo sapiens, GI205277386, Length=687, Percent_Identity=35.8078602620087, Blast_Score=385, Evalue=1e-107,
Organism=Homo sapiens, GI29570798, Length=201, Percent_Identity=27.363184079602, Blast_Score=69, Evalue=2e-11,
Organism=Escherichia coli, GI1790167, Length=611, Percent_Identity=48.772504091653, Blast_Score=558, Evalue=1e-160,
Organism=Escherichia coli, GI1788651, Length=214, Percent_Identity=33.6448598130841, Blast_Score=90, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17539970, Length=713, Percent_Identity=34.7826086956522, Blast_Score=368, Evalue=1e-102,
Organism=Caenorhabditis elegans, GI17532899, Length=716, Percent_Identity=34.2178770949721, Blast_Score=364, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI17532897, Length=431, Percent_Identity=38.5150812064965, Blast_Score=284, Evalue=8e-77,
Organism=Saccharomyces cerevisiae, GI6322745, Length=450, Percent_Identity=38, Blast_Score=273, Evalue=5e-74,
Organism=Saccharomyces cerevisiae, GI6323731, Length=433, Percent_Identity=30.4849884526559, Blast_Score=190, Evalue=4e-49,
Organism=Saccharomyces cerevisiae, GI6323730, Length=207, Percent_Identity=34.2995169082126, Blast_Score=110, Evalue=8e-25,
Organism=Saccharomyces cerevisiae, GI6323958, Length=167, Percent_Identity=30.5389221556886, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21357745, Length=690, Percent_Identity=37.536231884058, Blast_Score=412, Evalue=1e-115,
Organism=Drosophila melanogaster, GI28573187, Length=214, Percent_Identity=28.9719626168224, Blast_Score=67, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLMS_RHILO (Q98LX5)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_102552.1
- ProteinModelPortal:   Q98LX5
- SMR:   Q98LX5
- GeneID:   1225215
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mll0833
- NMPDR:   fig|266835.1.peg.657
- HOGENOM:   HBG645312
- OMA:   FGKNAKS
- ProtClustDB:   PRK00331
- BRENDA:   2.6.1.16
- GO:   GO:0005737
- HAMAP:   MF_00164
- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347
- TIGRFAMs:   TIGR01135

Pfam domain/function: PF00310 GATase_2; PF01380 SIS

EC number: =2.6.1.16

Molecular weight: Translated: 66440; Mature: 66440

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS51278 GATASE_TYPE_2; PS51464 SIS; PS00443 GATASE_TYPE_II

Important sites: ACT_SITE 2-2 ACT_SITE 602-602

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGIVGIVGHSQVAPLIVDALKRLEYRGYDSAGVATIEHGELARRRAEGKLINLERRLKE
CCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECHHHHHHHHCCCEEEHHHHHHC
EPLDGTIGIGHTRWATHGVPNETNAHPHFSDGVAIVHNGIIENFAELRDELVRDGYAFSS
CCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
QTDTEVVAHLVARELAKGLKPVEAAHQALKRLEGAFALAIMFKGDEDLIVGARNGPPLAV
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEEEECCCCEEEECCCCCCEEE
GHGDGEMFLGSDAIALAPFTNSITYLEDGDWAVVRRDSVAIFDIDGKKVERKRQQSLSTS
ECCCCCEEECCCCEEEECCCCCEEEEECCCEEEEEECCEEEEECCCHHHHHHHHHHCCCE
FMVDKGNRRHFMEKEIHEQPEVISHTLAHYVDFVSGVSKPLDLPFDFAKIGRLAISACGT
EEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
AYLAGLIGKYWFERYARLPVDIDVASEFRYREMPLSANDAAFFISQSGETADTLASLRYC
HHHHHHHHHHHHHHHHCCCCEEEHHCCCHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHH
RKAGMKIGAVVNVRESTMARESDVVLPTLAGPEIGVASTKAFTCQLSVLASLAVRAGVAR
HHCCCEEEEEEEEHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
GVISQEQEKTLVRALSEAPRYANQVLKLEEQIERIARELSRYKDVLYLGRDTNFPLAMEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCEEECC
ALKLKEISYIHAEGYAAGELKHGPIALIDENMPVIVIAPHDRIFEKTVSNMQEVAARGGK
CEEEHHEEEEEECCCCCCCCCCCCEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHCCCE
IILITDSKGAAQVSVKTMETIILPDVPEIISPIIYALPIQMLAYFAAVFMGTDVDQPRNL
EEEEECCCCCCEEEHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
AKSVTVE
HHHCCCC
>Mature Secondary Structure
MCGIVGIVGHSQVAPLIVDALKRLEYRGYDSAGVATIEHGELARRRAEGKLINLERRLKE
CCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECHHHHHHHHCCCEEEHHHHHHC
EPLDGTIGIGHTRWATHGVPNETNAHPHFSDGVAIVHNGIIENFAELRDELVRDGYAFSS
CCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
QTDTEVVAHLVARELAKGLKPVEAAHQALKRLEGAFALAIMFKGDEDLIVGARNGPPLAV
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEEEECCCCEEEECCCCCCEEE
GHGDGEMFLGSDAIALAPFTNSITYLEDGDWAVVRRDSVAIFDIDGKKVERKRQQSLSTS
ECCCCCEEECCCCEEEECCCCCEEEEECCCEEEEEECCEEEEECCCHHHHHHHHHHCCCE
FMVDKGNRRHFMEKEIHEQPEVISHTLAHYVDFVSGVSKPLDLPFDFAKIGRLAISACGT
EEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
AYLAGLIGKYWFERYARLPVDIDVASEFRYREMPLSANDAAFFISQSGETADTLASLRYC
HHHHHHHHHHHHHHHHCCCCEEEHHCCCHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHH
RKAGMKIGAVVNVRESTMARESDVVLPTLAGPEIGVASTKAFTCQLSVLASLAVRAGVAR
HHCCCEEEEEEEEHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
GVISQEQEKTLVRALSEAPRYANQVLKLEEQIERIARELSRYKDVLYLGRDTNFPLAMEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCEEECC
ALKLKEISYIHAEGYAAGELKHGPIALIDENMPVIVIAPHDRIFEKTVSNMQEVAARGGK
CEEEHHEEEEEECCCCCCCCCCCCEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHCCCE
IILITDSKGAAQVSVKTMETIILPDVPEIISPIIYALPIQMLAYFAAVFMGTDVDQPRNL
EEEEECCCCCCEEEHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
AKSVTVE
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11214968