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The map label for this gene is moaC

Identifier: 13470816

GI number: 13470816

Start: 481297

End: 481779

Strand: Direct

Name: moaC

Synonym: mlr0616

Alternate gene names: 13470816

Gene position: 481297-481779 (Clockwise)

Preceding gene: 13470815

Following gene: 13470817

Centisome position: 6.84

GC content: 62.94

Gene sequence:

>483_bases
ATGACATCAGCCCTCACCCATCTCGGCGCGCAGGGCGAGGCCAATATGGTCGATGTCGGCGACAAGGAAGAGACGACGCG
CACGGCGATCGCAGAAGGGTTCGTCTCGATGCAGCCCGAGACGCTGAAGACCATCCTCGCCGGCAACGCCAAGAAGGGCG
ATGTGCTGGGCACTGCCCGCATCGCCGGCATCATGGCGGCGAAGAAGACGCATGAATTGATCCCGCTCTGCCATCCGCTG
CTCTTGACCAAGATTTCAGTAGACATCGAGCCCGACCATGCGCTGCCCGGCCTGAAAGTCACCGCGTTGGCGCGTGTCAC
CGGCAAGACGGGCGTTGAGATGGAGGCGCTGACCGCAGCATCGGTCGCCTGCCTGACCATTTACGACATGGCCAAGGCGG
TCGACCGCGCCATGCTCATCTCCGGCATCCGCCTGGTCGAAAAGACCGGCGGCAAATCCGGCGACTATAAGGTTGGCGCC
TGA

Upstream 100 bases:

>100_bases
GCACCTTCCTTGTCGGCGAGAGCCTGATGCGGCAGGAGGATGTCACCGCGGCGACCCGCATTCTGCTGACGGGCAAGGCG
CTGGCCGAGGTCGTCTGACG

Downstream 100 bases:

>100_bases
TGGCGCTGGTTCCGGTGGCGGAGGCGCTTGAGCGCCTGCTGGATGGTGCAGCCCCCCTGGCCGGCGAAAGCGTCCCTCTG
TTCGAGGCCGTCGATCGTGT

Product: molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 160; Mature: 159

Protein sequence:

>160_residues
MTSALTHLGAQGEANMVDVGDKEETTRTAIAEGFVSMQPETLKTILAGNAKKGDVLGTARIAGIMAAKKTHELIPLCHPL
LLTKISVDIEPDHALPGLKVTALARVTGKTGVEMEALTAASVACLTIYDMAKAVDRAMLISGIRLVEKTGGKSGDYKVGA

Sequences:

>Translated_160_residues
MTSALTHLGAQGEANMVDVGDKEETTRTAIAEGFVSMQPETLKTILAGNAKKGDVLGTARIAGIMAAKKTHELIPLCHPL
LLTKISVDIEPDHALPGLKVTALARVTGKTGVEMEALTAASVACLTIYDMAKAVDRAMLISGIRLVEKTGGKSGDYKVGA
>Mature_159_residues
TSALTHLGAQGEANMVDVGDKEETTRTAIAEGFVSMQPETLKTILAGNAKKGDVLGTARIAGIMAAKKTHELIPLCHPLL
LTKISVDIEPDHALPGLKVTALARVTGKTGVEMEALTAASVACLTIYDMAKAVDRAMLISGIRLVEKTGGKSGDYKVGA

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family

Homologues:

Organism=Escherichia coli, GI1787001, Length=160, Percent_Identity=61.25, Blast_Score=190, Evalue=4e-50,
Organism=Caenorhabditis elegans, GI32566331, Length=153, Percent_Identity=45.0980392156863, Blast_Score=135, Evalue=1e-32,
Organism=Drosophila melanogaster, GI28574490, Length=155, Percent_Identity=49.0322580645161, Blast_Score=135, Evalue=8e-33,
Organism=Drosophila melanogaster, GI28574492, Length=142, Percent_Identity=48.5915492957746, Blast_Score=124, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MOAC_RHILO (Q98ME2)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_102385.1
- ProteinModelPortal:   Q98ME2
- SMR:   Q98ME2
- GeneID:   1225048
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mlr0616
- NMPDR:   fig|266835.1.peg.490
- HOGENOM:   HBG605231
- OMA:   PMCHPLM
- ProtClustDB:   PRK09364
- HAMAP:   MF_01224_B
- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820
- Gene3D:   G3DSA:3.30.70.640
- TIGRFAMs:   TIGR00581

Pfam domain/function: PF01967 MoaC; SSF55040 MoaC

EC number: NA

Molecular weight: Translated: 16656; Mature: 16524

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: NA

Important sites: ACT_SITE 129-129

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSALTHLGAQGEANMVDVGDKEETTRTAIAEGFVSMQPETLKTILAGNAKKGDVLGTAR
CCCCHHHCCCCCCCCEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCHHHHH
IAGIMAAKKTHELIPLCHPLLLTKISVDIEPDHALPGLKVTALARVTGKTGVEMEALTAA
HHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCEEEEEEEECCCCCCCHHHHHHH
SVACLTIYDMAKAVDRAMLISGIRLVEKTGGKSGDYKVGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCC
>Mature Secondary Structure 
TSALTHLGAQGEANMVDVGDKEETTRTAIAEGFVSMQPETLKTILAGNAKKGDVLGTAR
CCCHHHCCCCCCCCEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCHHHHH
IAGIMAAKKTHELIPLCHPLLLTKISVDIEPDHALPGLKVTALARVTGKTGVEMEALTAA
HHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCEEEEEEEECCCCCCCHHHHHHH
SVACLTIYDMAKAVDRAMLISGIRLVEKTGGKSGDYKVGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968