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The map label for this gene is ackA

Identifier: 13358047

GI number: 13358047

Start: 576679

End: 577842

Strand: Direct

Name: ackA

Synonym: UU484

Alternate gene names: 13358047

Gene position: 576679-577842 (Clockwise)

Preceding gene: 13358043

Following gene: 13358053

Centisome position: 76.71

GC content: 24.4

Gene sequence:

>1164_bases
ATGATGTTAATAATTAATATTGGTAGTAGTAGTTGAAAATTTTGCTTGTTTGATATGAATTTAAAACAAATATTTAGTGG
CAAAATTCGCTTAGACGTTAGCCCACACCAACTAAAATATATCTTTGATAAAAATGAATATGTTTATTTACTTGATGATG
ATCACAACAATCACGTTGATTTAATCATTAAATTTTTAATTAACAAAAAAATTATTAAAAAATTAGAAGATATCACTTAT
TTTGGAATTCGAGCTGTTTATGTTAAAAATTTTTATGGAGCAAGTGCTTTTTTAAATAATGAAATTTATAATGATCTTAA
CCAACACACAGATTTATGTCCTATTCACAACCAAAATACTATCATGTTAATTAATGACATTAAGCATTTAAACACCTCTG
CAAAAATTATTATTATTTTTGATAATTGGTTTCATCGTAGTATTAATAAAAATAAATACACTATTGCTATTGATCAAACA
ATAGCAATAAAACATAAAATTCGTAAATATGGTTTTCATGGAATTTCTTTTAGTTATAGTAATAAAATAATGCAAAATTA
TTTAGGAAAACAAGATGTTAATTTAATTATTTTACACTTAGGTTCTGGATCGTCAGTTTGTGCAATTAAAAATGGAAAAT
CATTTGATACCTCAATGTCTTACTCTCCTCTTTCAGGAATTATTATGAATACAAGAAGTGGTGATATAGACCCTAGTGTT
TTACTTACTTTAAAAAAAGTAAAAAACCAATCACTGAAGCAATTGATCTTATTTTTAAATCAGCAATCAGGTCTTTATGG
ATTAACAAAACATCATAGTATTAGTGAAGTTGCTAATAATTTGCACAATAAAAATAATGAACTTGCCCTTGAGATGTACA
CTGATAGCATTGTTGATTATTTTATTAAGTATTTAAACCATTTACAAAAGATTGATGCAATTGTATTTTCGGGAGGAATT
AGTGAATTTGAGCATCTTGTTTTAGAAAAAATTATTAGTAAAATTCATCTAATAAACCTTGAAATTAACGATCATTTAAT
ACTAACAAACACGTTAAATAAAATTTCAACATCTAAATCACAAATTCCTATATATTTATGTTTAGTGAATGAAGAGCACG
AAATTGCTTATGAAATGCTAAATTTAATTAATAAGACAAAATAA

Upstream 100 bases:

>100_bases
AGCATATGCACATATAGTAAAATAATAAATAAAGTGCTGATCAAAAGCCAGAATTGTTTATTTTTGGTTTTAAAGTTTAG
TTAATAAGTGGTGGTTAATT

Downstream 100 bases:

>100_bases
AAATTATTCATGATAGTCAGCACTATGAATAATAGAAAAATACTTATCTAATGATTTGTTAAATTCAATATTTTGATTAT
TTACTTTAACATCAACAAAA

Product: acetate kinase

Products: NA

Alternate protein names: Acetokinase [H]

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MMLIINIGSSSWKFCLFDMNLKQIFSGKIRLDVSPHQLKYIFDKNEYVYLLDDDHNNHVDLIIKFLINKKIIKKLEDITY
FGIRAVYVKNFYGASAFLNNEIYNDLNQHTDLCPIHNQNTIMLINDIKHLNTSAKIIIIFDNWFHRSINKNKYTIAIDQT
IAIKHKIRKYGFHGISFSYSNKIMQNYLGKQDVNLIILHLGSGSSVCAIKNGKSFDTSMSYSPLSGIIMNTRSGDIDPSV
LLTLKKVKNQSLKQLILFLNQQSGLYGLTKHHSISEVANNLHNKNNELALEMYTDSIVDYFIKYLNHLQKIDAIVFSGGI
SEFEHLVLEKIISKIHLINLEINDHLILTNTLNKISTSKSQIPIYLCLVNEEHEIAYEMLNLINKTK

Sequences:

>Translated_387_residues
MMLIINIGSSS*KFCLFDMNLKQIFSGKIRLDVSPHQLKYIFDKNEYVYLLDDDHNNHVDLIIKFLINKKIIKKLEDITY
FGIRAVYVKNFYGASAFLNNEIYNDLNQHTDLCPIHNQNTIMLINDIKHLNTSAKIIIIFDNWFHRSINKNKYTIAIDQT
IAIKHKIRKYGFHGISFSYSNKIMQNYLGKQDVNLIILHLGSGSSVCAIKNGKSFDTSMSYSPLSGIIMNTRSGDIDPSV
LLTLKKVKNQSLKQLILFLNQQSGLYGLTKHHSISEVANNLHNKNNELALEMYTDSIVDYFIKYLNHLQKIDAIVFSGGI
SEFEHLVLEKIISKIHLINLEINDHLILTNTLNKISTSKSQIPIYLCLVNEEHEIAYEMLNLINKTK
>Mature_387_residues
MMLIINIGSSS*KFCLFDMNLKQIFSGKIRLDVSPHQLKYIFDKNEYVYLLDDDHNNHVDLIIKFLINKKIIKKLEDITY
FGIRAVYVKNFYGASAFLNNEIYNDLNQHTDLCPIHNQNTIMLINDIKHLNTSAKIIIIFDNWFHRSINKNKYTIAIDQT
IAIKHKIRKYGFHGISFSYSNKIMQNYLGKQDVNLIILHLGSGSSVCAIKNGKSFDTSMSYSPLSGIIMNTRSGDIDPSV
LLTLKKVKNQSLKQLILFLNQQSGLYGLTKHHSISEVANNLHNKNNELALEMYTDSIVDYFIKYLNHLQKIDAIVFSGGI
SEFEHLVLEKIISKIHLINLEINDHLILTNTLNKISTSKSQIPIYLCLVNEEHEIAYEMLNLINKTK

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family [H]

Homologues:

Organism=Escherichia coli, GI145693184, Length=390, Percent_Identity=26.4102564102564, Blast_Score=165, Evalue=4e-42,
Organism=Escherichia coli, GI1788633, Length=396, Percent_Identity=29.5454545454545, Blast_Score=161, Evalue=9e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000890
- InterPro:   IPR004372 [H]

Pfam domain/function: PF00871 Acetate_kinase [H]

EC number: =2.7.2.1 [H]

Molecular weight: Translated: 44383; Mature: 44383

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMLIINIGSSSKFCLFDMNLKQIFSGKIRLDVSPHQLKYIFDKNEYVYLLDDDHNNHVDL
CEEEEEECCCCEEEEEECCHHHHHCCCEEEEECHHEEEEEEECCCEEEEEECCCCCHHHH
IIKFLINKKIIKKLEDITYFGIRAVYVKNFYGASAFLNNEIYNDLNQHTDLCPIHNQNTI
HHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCHHHHCHHHHHHHHCCCCCCEECCCCEE
MLINDIKHLNTSAKIIIIFDNWFHRSINKNKYTIAIDQTIAIKHKIRKYGFHGISFSYSN
EEEECCHHCCCCEEEEEEEECCHHCCCCCCEEEEEEECEEHHHHHHHHHCCCCEEEHHHH
KIMQNYLGKQDVNLIILHLGSGSSVCAIKNGKSFDTSMSYSPLSGIIMNTRSGDIDPSVL
HHHHHHCCCCCCEEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCEEEECCCCCCCHHHH
LTLKKVKNQSLKQLILFLNQQSGLYGLTKHHSISEVANNLHNKNNELALEMYTDSIVDYF
HHHHHHHCHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHCCCCCCEEEEEHHHHHHHHH
IKYLNHLQKIDAIVFSGGISEFEHLVLEKIISKIHLINLEINDHLILTNTLNKISTSKSQ
HHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHEEEEEEEECCEEEEEECHHHHCCCCCC
IPIYLCLVNEEHEIAYEMLNLINKTK
CEEEEEEECCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMLIINIGSSSKFCLFDMNLKQIFSGKIRLDVSPHQLKYIFDKNEYVYLLDDDHNNHVDL
CEEEEEECCCCEEEEEECCHHHHHCCCEEEEECHHEEEEEEECCCEEEEEECCCCCHHHH
IIKFLINKKIIKKLEDITYFGIRAVYVKNFYGASAFLNNEIYNDLNQHTDLCPIHNQNTI
HHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCHHHHCHHHHHHHHCCCCCCEECCCCEE
MLINDIKHLNTSAKIIIIFDNWFHRSINKNKYTIAIDQTIAIKHKIRKYGFHGISFSYSN
EEEECCHHCCCCEEEEEEEECCHHCCCCCCEEEEEEECEEHHHHHHHHHCCCCEEEHHHH
KIMQNYLGKQDVNLIILHLGSGSSVCAIKNGKSFDTSMSYSPLSGIIMNTRSGDIDPSVL
HHHHHHCCCCCCEEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCEEEECCCCCCCHHHH
LTLKKVKNQSLKQLILFLNQQSGLYGLTKHHSISEVANNLHNKNNELALEMYTDSIVDYF
HHHHHHHCHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHCCCCCCEEEEEHHHHHHHHH
IKYLNHLQKIDAIVFSGGISEFEHLVLEKIISKIHLINLEINDHLILTNTLNKISTSKSQ
HHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHEEEEEEEECCEEEEEECHHHHCCCCCC
IPIYLCLVNEEHEIAYEMLNLINKTK
CEEEEEEECCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12949158 [H]