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The map label for this gene is lytC [H]

Identifier: 126698620

GI number: 126698620

Start: 1217070

End: 1219103

Strand: Direct

Name: lytC [H]

Synonym: CD1036

Alternate gene names: 126698620

Gene position: 1217070-1219103 (Clockwise)

Preceding gene: 126698619

Following gene: 126698621

Centisome position: 28.37

GC content: 30.53

Gene sequence:

>2034_bases
ATGTTAAGTAAGGAGATTAATATGAGAAGAAATACAAAATTATTAACAACAGGGATTCTTTCAATGGCAATCGTCGCACC
TACAATGGCATTTGCTACTGAATCTAATGCTATGGAAAATAACGCTGATTTAAATATAAACTTAGAGAAAAAAAGTATCG
TTTTAGGTAGCAAATCAAAAGTTAGTGTCAAATTTAAAGAAAAACCAGATGCAGATAGCATTAAATTAAAGTATAAATGC
TATGACATGCCATTGAATACAACTCTAAATTACAATCAATCAACTGGGGCATATGAAGGAATTATCAATTATAATAAAGA
CCCAGAATATCTAAATGTTTGGGAACTACAAGGGATAACAATAAACAGCAAAACTAATCCTAAAACTTTAAACAGACAAG
ACCTAGAAAAGATGGGATTAAATTTAAAAGACTATAATGTAACACAGGAATGTATAATTGAAGACATAACTTCTAGAAAA
GATGTAAATAAATATTTGAGAAAAACTTCTTCACCTATTACAGAACTTACAGGAAGTGATAGATATGAAACAGCAGTTAA
AATAAGTAAAGAGGGCTGGAAAAATGGTTCAGATAAAGTAGTTATAATAAATGGAGATGTAAGTATAGATGGCATTATAT
CAACTCCACTGGCAACCACATATAATGCACCAATACTTTTGGTTGAAAAAAACAATGTGCCTAATAGTGTAAAATCAGAA
TTAAAGCGCCTAAACCCTAAAGATATAATTATAATTGGAGATGAGAATGCTATTTCTAAAACTACTGCTAATCAAATTAA
ATCAACTGTAAATGCTAGTCAAACACGTTTAAATGGTTCTAATAGATATGAGACATCTTTATTGATAGCAAAGGAAATAG
ATAAAAATCATGATGTGGAAAAAGTATACATAACAAATGCTAATGGCGGAGAAGTGGATGCACTTACTATAGCAGCAAAA
GCAGGTCAAGACAAGCAACCAATTATATTAACTGATAAAGATAGTATTACAGACAATACATATAAATGGTTAAAGAGTGA
GGATTTACAAAATGCTTATTTTATAGGTGGTCCTCAAATGATATCAACAAATGTTATAAATAAGGTAAATGGAATAACTA
AAGATAGTGTTACTAATAATAGAGTATACGGAGCAGATAGACACGAAACAAATGCAAACGTAATAAAAAAATTCTATACA
GATGATGAGTTAGAGGCTGTTTTAGTAGCTAAATCAGATGTACTTGTTGATGCTTTAGCAGCAGGTCCATTGGCTGCGAA
CTTAAAATCTCCAATACTTATAACACCAAAGACATATGTATCTGCATACCATAAAGATAATTTAGAAGCTAAATCAGCTA
ATAAAGTATACAAAATAGGAGGAGGATTGACTTCTAAGGTAATGAGCTCTATAGCATCATCATTATCTAAACACAATACG
ACTCCAACAGAACCAGGAAATAGTGGGGGCAAGACAGTTATGATTGACCCAGGGCATGGTGGTTCAGCACCTGGAAATTC
ATCTGGAGGAATGATTGAAAAAGATTACAATTTAAATACTTCACTTGCAACAACTGAATATTTACGTTCAAAGGGATTCA
ATGTAATAATGACAAGAGACACAGATAAGACTTTATCTCTTGGAAATAGAACTGCTCTATCTAATTCATTGAAACCAGAT
TTATTTACAAGTATACATTATAATGGCTCAACTAATAAACAAGGTCATGGTGTAGAAGTATTTTATAAGCTTAAAGATAA
AAATGGAGGGACTACTAAAACTGTAGCTACCAATATATTAAATAGAATTTTAGAGAAATTTAAACTTACAAATAGAGGTA
TAAAAACAAGAGTACTTCCTAGTGATTCTACAAAAGATTATTTATACGTTTTAAGAAGTAATGATATGCCAGCTGTACTT
GTAGAATGTGCATTTTTGGATAATGAAAATGATATGAGTTTAATAAACTCATCTGCAAAAGTAAAAGAAATGGGTACACA
AATAGGTAAAGGAATAGAAGATTCATTAAAATAA

Upstream 100 bases:

>100_bases
GTTTATTTTTATATATTACTTATATATTATTTATATTTTGGGTTAGATACACTTTGACATATTTTCAAAAGTTAAAAGAT
TAAAAATAAAGTAGAAATTT

Downstream 100 bases:

>100_bases
ATGGAAATAAAAATATTTAAAAACTTAATGTAAATTTATAGTTGTAAATTTATACTAAAGTCAAAAAATGAAATATAAGT
GTATCAATAGTAAGACTGTA

Product: N-acetylmuramoyl-L-alanine amidase

Products: NA

Alternate protein names: Cell wall hydrolase; Cell wall-associated polypeptide CWBP49; CWBP49; Major autolysin [H]

Number of amino acids: Translated: 677; Mature: 677

Protein sequence:

>677_residues
MLSKEINMRRNTKLLTTGILSMAIVAPTMAFATESNAMENNADLNINLEKKSIVLGSKSKVSVKFKEKPDADSIKLKYKC
YDMPLNTTLNYNQSTGAYEGIINYNKDPEYLNVWELQGITINSKTNPKTLNRQDLEKMGLNLKDYNVTQECIIEDITSRK
DVNKYLRKTSSPITELTGSDRYETAVKISKEGWKNGSDKVVIINGDVSIDGIISTPLATTYNAPILLVEKNNVPNSVKSE
LKRLNPKDIIIIGDENAISKTTANQIKSTVNASQTRLNGSNRYETSLLIAKEIDKNHDVEKVYITNANGGEVDALTIAAK
AGQDKQPIILTDKDSITDNTYKWLKSEDLQNAYFIGGPQMISTNVINKVNGITKDSVTNNRVYGADRHETNANVIKKFYT
DDELEAVLVAKSDVLVDALAAGPLAANLKSPILITPKTYVSAYHKDNLEAKSANKVYKIGGGLTSKVMSSIASSLSKHNT
TPTEPGNSGGKTVMIDPGHGGSAPGNSSGGMIEKDYNLNTSLATTEYLRSKGFNVIMTRDTDKTLSLGNRTALSNSLKPD
LFTSIHYNGSTNKQGHGVEVFYKLKDKNGGTTKTVATNILNRILEKFKLTNRGIKTRVLPSDSTKDYLYVLRSNDMPAVL
VECAFLDNENDMSLINSSAKVKEMGTQIGKGIEDSLK

Sequences:

>Translated_677_residues
MLSKEINMRRNTKLLTTGILSMAIVAPTMAFATESNAMENNADLNINLEKKSIVLGSKSKVSVKFKEKPDADSIKLKYKC
YDMPLNTTLNYNQSTGAYEGIINYNKDPEYLNVWELQGITINSKTNPKTLNRQDLEKMGLNLKDYNVTQECIIEDITSRK
DVNKYLRKTSSPITELTGSDRYETAVKISKEGWKNGSDKVVIINGDVSIDGIISTPLATTYNAPILLVEKNNVPNSVKSE
LKRLNPKDIIIIGDENAISKTTANQIKSTVNASQTRLNGSNRYETSLLIAKEIDKNHDVEKVYITNANGGEVDALTIAAK
AGQDKQPIILTDKDSITDNTYKWLKSEDLQNAYFIGGPQMISTNVINKVNGITKDSVTNNRVYGADRHETNANVIKKFYT
DDELEAVLVAKSDVLVDALAAGPLAANLKSPILITPKTYVSAYHKDNLEAKSANKVYKIGGGLTSKVMSSIASSLSKHNT
TPTEPGNSGGKTVMIDPGHGGSAPGNSSGGMIEKDYNLNTSLATTEYLRSKGFNVIMTRDTDKTLSLGNRTALSNSLKPD
LFTSIHYNGSTNKQGHGVEVFYKLKDKNGGTTKTVATNILNRILEKFKLTNRGIKTRVLPSDSTKDYLYVLRSNDMPAVL
VECAFLDNENDMSLINSSAKVKEMGTQIGKGIEDSLK
>Mature_677_residues
MLSKEINMRRNTKLLTTGILSMAIVAPTMAFATESNAMENNADLNINLEKKSIVLGSKSKVSVKFKEKPDADSIKLKYKC
YDMPLNTTLNYNQSTGAYEGIINYNKDPEYLNVWELQGITINSKTNPKTLNRQDLEKMGLNLKDYNVTQECIIEDITSRK
DVNKYLRKTSSPITELTGSDRYETAVKISKEGWKNGSDKVVIINGDVSIDGIISTPLATTYNAPILLVEKNNVPNSVKSE
LKRLNPKDIIIIGDENAISKTTANQIKSTVNASQTRLNGSNRYETSLLIAKEIDKNHDVEKVYITNANGGEVDALTIAAK
AGQDKQPIILTDKDSITDNTYKWLKSEDLQNAYFIGGPQMISTNVINKVNGITKDSVTNNRVYGADRHETNANVIKKFYT
DDELEAVLVAKSDVLVDALAAGPLAANLKSPILITPKTYVSAYHKDNLEAKSANKVYKIGGGLTSKVMSSIASSLSKHNT
TPTEPGNSGGKTVMIDPGHGGSAPGNSSGGMIEKDYNLNTSLATTEYLRSKGFNVIMTRDTDKTLSLGNRTALSNSLKPD
LFTSIHYNGSTNKQGHGVEVFYKLKDKNGGTTKTVATNILNRILEKFKLTNRGIKTRVLPSDSTKDYLYVLRSNDMPAVL
VECAFLDNENDMSLINSSAKVKEMGTQIGKGIEDSLK

Specific function: Autolysins are involved in some important biological processes such as cell separation, cell-wall turnover, competence for genetic transformation, formation of the flagella - in particular of its basal body - and sporulation. Has a high affinity for teich

COG id: COG2247

COG function: function code M; Putative cell wall-binding domain

Gene ontology:

Cell location: Secreted, cell wall [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007253
- InterPro:   IPR002508 [H]

Pfam domain/function: PF01520 Amidase_3; PF04122 CW_binding_2 [H]

EC number: =3.5.1.28 [H]

Molecular weight: Translated: 74196; Mature: 74196

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSKEINMRRNTKLLTTGILSMAIVAPTMAFATESNAMENNADLNINLEKKSIVLGSKSK
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCEEEECCCCE
VSVKFKEKPDADSIKLKYKCYDMPLNTTLNYNQSTGAYEGIINYNKDPEYLNVWELQGIT
EEEEECCCCCCCCEEEEEEEEECCCCCEECCCCCCCCEECEEECCCCCCEEEEEEEEEEE
INSKTNPKTLNRQDLEKMGLNLKDYNVTQECIIEDITSRKDVNKYLRKTSSPITELTGSD
ECCCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCC
RYETAVKISKEGWKNGSDKVVIINGDVSIDGIISTPLATTYNAPILLVEKNNVPNSVKSE
CEEEEEEEEHHCCCCCCCEEEEEECCEEECCEECCCCCCCCCCCEEEEECCCCCHHHHHH
LKRLNPKDIIIIGDENAISKTTANQIKSTVNASQTRLNGSNRYETSLLIAKEIDKNHDVE
HHHCCCCEEEEECCCCCCHHHHHHHHHHHHCHHHHCCCCCCCEEEEEEEEECCCCCCCCE
KVYITNANGGEVDALTIAAKAGQDKQPIILTDKDSITDNTYKWLKSEDLQNAYFIGGPQM
EEEEECCCCCCEEEEEEEECCCCCCCCEEEECCCCCCCHHHHHHHCCCCCCEEEECCCCE
ISTNVINKVNGITKDSVTNNRVYGADRHETNANVIKKFYTDDELEAVLVAKSDVLVDALA
EHHHHHHHHCCCCCCCCCCCEEECCCCCCCCHHHHHHHCCCCCCEEEEEECCCHHHHHHH
AGPLAANLKSPILITPKTYVSAYHKDNLEAKSANKVYKIGGGLTSKVMSSIASSLSKHNT
CCCCHHCCCCCEEECCHHHHHHHHCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHCCC
TPTEPGNSGGKTVMIDPGHGGSAPGNSSGGMIEKDYNLNTSLATTEYLRSKGFNVIMTRD
CCCCCCCCCCCEEEEECCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHCCCEEEEECC
TDKTLSLGNRTALSNSLKPDLFTSIHYNGSTNKQGHGVEVFYKLKDKNGGTTKTVATNIL
CCCHHCCCCCHHHCCCCCCCCEEEEEECCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHH
NRILEKFKLTNRGIKTRVLPSDSTKDYLYVLRSNDMPAVLVECAFLDNENDMSLINSSAK
HHHHHHHHHHCCCCEEEECCCCCCCCEEEEEECCCCCEEEEEEEEECCCCCHHHHCCCHH
VKEMGTQIGKGIEDSLK
HHHHHHHHCCCHHHHCC
>Mature Secondary Structure
MLSKEINMRRNTKLLTTGILSMAIVAPTMAFATESNAMENNADLNINLEKKSIVLGSKSK
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCEEEECCCCE
VSVKFKEKPDADSIKLKYKCYDMPLNTTLNYNQSTGAYEGIINYNKDPEYLNVWELQGIT
EEEEECCCCCCCCEEEEEEEEECCCCCEECCCCCCCCEECEEECCCCCCEEEEEEEEEEE
INSKTNPKTLNRQDLEKMGLNLKDYNVTQECIIEDITSRKDVNKYLRKTSSPITELTGSD
ECCCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCC
RYETAVKISKEGWKNGSDKVVIINGDVSIDGIISTPLATTYNAPILLVEKNNVPNSVKSE
CEEEEEEEEHHCCCCCCCEEEEEECCEEECCEECCCCCCCCCCCEEEEECCCCCHHHHHH
LKRLNPKDIIIIGDENAISKTTANQIKSTVNASQTRLNGSNRYETSLLIAKEIDKNHDVE
HHHCCCCEEEEECCCCCCHHHHHHHHHHHHCHHHHCCCCCCCEEEEEEEEECCCCCCCCE
KVYITNANGGEVDALTIAAKAGQDKQPIILTDKDSITDNTYKWLKSEDLQNAYFIGGPQM
EEEEECCCCCCEEEEEEEECCCCCCCCEEEECCCCCCCHHHHHHHCCCCCCEEEECCCCE
ISTNVINKVNGITKDSVTNNRVYGADRHETNANVIKKFYTDDELEAVLVAKSDVLVDALA
EHHHHHHHHCCCCCCCCCCCEEECCCCCCCCHHHHHHHCCCCCCEEEEEECCCHHHHHHH
AGPLAANLKSPILITPKTYVSAYHKDNLEAKSANKVYKIGGGLTSKVMSSIASSLSKHNT
CCCCHHCCCCCEEECCHHHHHHHHCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHCCC
TPTEPGNSGGKTVMIDPGHGGSAPGNSSGGMIEKDYNLNTSLATTEYLRSKGFNVIMTRD
CCCCCCCCCCCEEEEECCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHCCCEEEEECC
TDKTLSLGNRTALSNSLKPDLFTSIHYNGSTNKQGHGVEVFYKLKDKNGGTTKTVATNIL
CCCHHCCCCCHHHCCCCCCCCEEEEEECCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHH
NRILEKFKLTNRGIKTRVLPSDSTKDYLYVLRSNDMPAVLVECAFLDNENDMSLINSSAK
HHHHHHHHHHCCCCEEEECCCCCCCCEEEEEECCCCCEEEEEEEEECCCCCHHHHCCCHH
VKEMGTQIGKGIEDSLK
HHHHHHHHCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1357079; 1682302; 9384377 [H]