Click here to switch to the map view.

The map label for this gene is melB [C]

Identifier: 126696847

GI number: 126696847

Start: 1277456

End: 1278802

Strand: Direct

Name: melB [C]

Synonym: P9301_15091

Alternate gene names: 126696847

Gene position: 1277456-1278802 (Clockwise)

Preceding gene: 126696846

Following gene: 126696848

Centisome position: 77.8

GC content: 35.19

Gene sequence:

>1347_bases
ATGTTCTCTTATGGACTAGGAGATGCAGGTACAGGTTTAGTCGCCACGCAATTTGGTTTTTTTCTATTCAAATTCTTTAT
TTCTGCTGGTTTACCAGTAATAATTGCAGGTTCATTATTAATGTTAATAAAGATATGGGATGCAGTAAATGATCCGTTAA
TTGGATGGTTAAGTGATCGTACTAAATCAAGATGGGGACCTAGAATCCCATGGATGGTAGTAGCATCTGTGCCCCTTGGT
TTCTCTTTAGCTGCGATATGGTGGACACCCGCTGGCTCCGTACTAACCAAGACTATTTACTATGCAATAATTTCTATAAT
CGTAATGACTGCTTATACGAGTATTAATCTCCCTTTTGCAGCTCTATCTACTGAAATTTCTGAAAAAACAGCAATAAGAA
CAAGACTAAACGCATCTAGATTTACTGGCTCAATAATTGCAGGACTAACTGGTTTAATAATTGCTGGAGTTGTATTAGGT
TCTGAAGGATCAGCAAATAATGAATATTTTTTAATGGGTAAAATAAGCGGATGTATTGCAGTTGCTGCAACATTGATTTC
TTGTTGGGGATTAGCTCCATTTGCCAAAAAAGCAAGAATGCCTTCAGGAAAAGTTGAAGCTATTTCACTTCAATTCAAAA
GGATCTTCAGAAATAAAAAATTTCTAAAAGTTATTACACTTTATATTCTCCTCTGGTGCGCCTTACAGTTGATGCAAACA
GTATCGTTAATCTATGTAGAGGATGTACTGAATGTTCCAACATATATTGCGAAGTGGATCCCGATACCTTTCCAAATTAG
CGCTTTAGTGGGTTTACAAATATGGACCAGAGTATCGAATAAATTGAACAGGATTTCAGCTTTAAACTATGGAGCGATTA
TGTGGATTGTTTCATGTACGGCAGCTTTATTTTTACCTTCACTATCAAAAATTTCAGGAGTTGGAGATAGTTTATTCCTA
AATGCCGGCAACATATTTCTCTTCATTCTTTTAATTTTCATAATCTGTCTTATTGGAGTAGGAGCTTCAACCGCTTTTCT
TATCCCTTGGTCACTACTTCCTGATGCAATAGACGAAGACCCAGAGAAACCTGCAGGATTATATACTGCTTGGATGGTAC
TTATTCAGAAGATTGGTATCGCGTTTAGTGTTCAATTATTAGGATTTTTATTGTATTTATCAGGCTATCAATCATGCATT
GTTGATAAAGGTGGTCAAAATATTGTTGAACAATGCTACTCAGCACAATTAACTATTAGATTATGTATTGGTTTTATACC
CTCAATATTGGTAATAATTGGTCTTTTAATCATGAGAAAATGGGATCGAAAATTAATTACAAACTAA

Upstream 100 bases:

>100_bases
AATTACCATTGCAATAATACATTATCAAACAATCAACAAAGCAAAAAGATTGGAAAATTCACACTCGAAAAAAAATATTA
CTAGATCAACAACAAGATTA

Downstream 100 bases:

>100_bases
TATAAAGATATGTATTCCCATAATTTTTTCAAAAGACTTCTAAGCAGCTTAATCATTGGCGGGCAAGCAATTAATTTTAT
CTTTAAGGGTAAAATTTCCA

Product: GPH family sugar transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MFSYGLGDAGTGLVATQFGFFLFKFFISAGLPVIIAGSLLMLIKIWDAVNDPLIGWLSDRTKSRWGPRIPWMVVASVPLG
FSLAAIWWTPAGSVLTKTIYYAIISIIVMTAYTSINLPFAALSTEISEKTAIRTRLNASRFTGSIIAGLTGLIIAGVVLG
SEGSANNEYFLMGKISGCIAVAATLISCWGLAPFAKKARMPSGKVEAISLQFKRIFRNKKFLKVITLYILLWCALQLMQT
VSLIYVEDVLNVPTYIAKWIPIPFQISALVGLQIWTRVSNKLNRISALNYGAIMWIVSCTAALFLPSLSKISGVGDSLFL
NAGNIFLFILLIFIICLIGVGASTAFLIPWSLLPDAIDEDPEKPAGLYTAWMVLIQKIGIAFSVQLLGFLLYLSGYQSCI
VDKGGQNIVEQCYSAQLTIRLCIGFIPSILVIIGLLIMRKWDRKLITN

Sequences:

>Translated_448_residues
MFSYGLGDAGTGLVATQFGFFLFKFFISAGLPVIIAGSLLMLIKIWDAVNDPLIGWLSDRTKSRWGPRIPWMVVASVPLG
FSLAAIWWTPAGSVLTKTIYYAIISIIVMTAYTSINLPFAALSTEISEKTAIRTRLNASRFTGSIIAGLTGLIIAGVVLG
SEGSANNEYFLMGKISGCIAVAATLISCWGLAPFAKKARMPSGKVEAISLQFKRIFRNKKFLKVITLYILLWCALQLMQT
VSLIYVEDVLNVPTYIAKWIPIPFQISALVGLQIWTRVSNKLNRISALNYGAIMWIVSCTAALFLPSLSKISGVGDSLFL
NAGNIFLFILLIFIICLIGVGASTAFLIPWSLLPDAIDEDPEKPAGLYTAWMVLIQKIGIAFSVQLLGFLLYLSGYQSCI
VDKGGQNIVEQCYSAQLTIRLCIGFIPSILVIIGLLIMRKWDRKLITN
>Mature_448_residues
MFSYGLGDAGTGLVATQFGFFLFKFFISAGLPVIIAGSLLMLIKIWDAVNDPLIGWLSDRTKSRWGPRIPWMVVASVPLG
FSLAAIWWTPAGSVLTKTIYYAIISIIVMTAYTSINLPFAALSTEISEKTAIRTRLNASRFTGSIIAGLTGLIIAGVVLG
SEGSANNEYFLMGKISGCIAVAATLISCWGLAPFAKKARMPSGKVEAISLQFKRIFRNKKFLKVITLYILLWCALQLMQT
VSLIYVEDVLNVPTYIAKWIPIPFQISALVGLQIWTRVSNKLNRISALNYGAIMWIVSCTAALFLPSLSKISGVGDSLFL
NAGNIFLFILLIFIICLIGVGASTAFLIPWSLLPDAIDEDPEKPAGLYTAWMVLIQKIGIAFSVQLLGFLLYLSGYQSCI
VDKGGQNIVEQCYSAQLTIRLCIGFIPSILVIIGLLIMRKWDRKLITN

Specific function: Unknown

COG id: COG2211

COG function: function code G; Na+/melibiose symporter and related transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:galactoside symporter (TC 2.A.2) family [H]

Homologues:

Organism=Homo sapiens, GI42713696, Length=437, Percent_Identity=21.9679633867277, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI211063479, Length=450, Percent_Identity=22, Blast_Score=66, Evalue=7e-11,
Organism=Escherichia coli, GI87082306, Length=446, Percent_Identity=22.8699551569507, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1786466, Length=409, Percent_Identity=23.960880195599, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1790561, Length=456, Percent_Identity=20.3947368421053, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI48994989, Length=404, Percent_Identity=22.2772277227723, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI1787902, Length=154, Percent_Identity=26.6233766233766, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016196
- InterPro:   IPR001927
- InterPro:   IPR018043 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 49026; Mature: 49026

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSYGLGDAGTGLVATQFGFFLFKFFISAGLPVIIAGSLLMLIKIWDAVNDPLIGWLSDR
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEHHHHH
TKSRWGPRIPWMVVASVPLGFSLAAIWWTPAGSVLTKTIYYAIISIIVMTAYTSINLPFA
HHCCCCCCCCEEEEEECCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
ALSTEISEKTAIRTRLNASRFTGSIIAGLTGLIIAGVVLGSEGSANNEYFLMGKISGCIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECHHHHHH
VAATLISCWGLAPFAKKARMPSGKVEAISLQFKRIFRNKKFLKVITLYILLWCALQLMQT
HHHHHHHHHCCCHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
VSLIYVEDVLNVPTYIAKWIPIPFQISALVGLQIWTRVSNKLNRISALNYGAIMWIVSCT
HHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
AALFLPSLSKISGVGDSLFLNAGNIFLFILLIFIICLIGVGASTAFLIPWSLLPDAIDED
HHHHHCCHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHCCCCCHHEEEEHHHCCHHHCCC
PEKPAGLYTAWMVLIQKIGIAFSVQLLGFLLYLSGYQSCIVDKGGQNIVEQCYSAQLTIR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LCIGFIPSILVIIGLLIMRKWDRKLITN
HHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFSYGLGDAGTGLVATQFGFFLFKFFISAGLPVIIAGSLLMLIKIWDAVNDPLIGWLSDR
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEHHHHH
TKSRWGPRIPWMVVASVPLGFSLAAIWWTPAGSVLTKTIYYAIISIIVMTAYTSINLPFA
HHCCCCCCCCEEEEEECCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
ALSTEISEKTAIRTRLNASRFTGSIIAGLTGLIIAGVVLGSEGSANNEYFLMGKISGCIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECHHHHHH
VAATLISCWGLAPFAKKARMPSGKVEAISLQFKRIFRNKKFLKVITLYILLWCALQLMQT
HHHHHHHHHCCCHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
VSLIYVEDVLNVPTYIAKWIPIPFQISALVGLQIWTRVSNKLNRISALNYGAIMWIVSCT
HHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
AALFLPSLSKISGVGDSLFLNAGNIFLFILLIFIICLIGVGASTAFLIPWSLLPDAIDED
HHHHHCCHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHCCCCCHHEEEEHHHCCHHHCCC
PEKPAGLYTAWMVLIQKIGIAFSVQLLGFLLYLSGYQSCIVDKGGQNIVEQCYSAQLTIR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LCIGFIPSILVIIGLLIMRKWDRKLITN
HHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]