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The map label for this gene is aroA

Identifier: 126695977

GI number: 126695977

Start: 568062

End: 569372

Strand: Reverse

Name: aroA

Synonym: P9301_06391

Alternate gene names: 126695977

Gene position: 569372-568062 (Counterclockwise)

Preceding gene: 126695984

Following gene: 126695976

Centisome position: 34.68

GC content: 36.61

Gene sequence:

>1311_bases
ATGAATAATATCCGCACAATTAAAGGTGGAGTTAATTTAAAAGGAAAAATAAAAGTACCAGGAGATAAATCCATCTCTCA
TAGAGCTTTAATAATTGGGAGTATTGCTGAGGGTGAAACGACTATTGAGGGGTTTTTATATTCTGAAGATCCCCTTTCAA
CTGCTGATTGTCTTAGAAAATTAGGTGTAAATATACCAGAAATAAAAAAAGATAAGCCTTTTACGATTTCAGGATTGGGT
ATTAATGGATTAAAAGAGCCCAAAGAGATTCTCAATTGCGGGAATTCGGGAACCACCATGAGATTATTAATGGGGTTACT
TGCCGGTCAAGAAGGCAAGAATTTTATCTTAACTGGTGATATTTCTCTTAATGAAAGGCCAATGGGGAGAGTGGGTAAAC
CATTATCATTGATGGGTGGCAAAATTTTTGGTAGAGAAAAAGGGAACAAAGCACCAATCTCAATTAATGGGAATAAACTA
AAAGGATGTGTTATGGGAACTCCAGTAGCGAGTGCTCAAGTAAAATCCGCAATCTTATTGGCAGGCCTCAAAGCTTCTGG
AACCACTTCTGTTATTGAACCAGCCTCTTCAAGAGATCATACTGAAAGAATGTTGAAAGCATTTGGAGCAGACATCACTA
TCAGAGGGGAATTTGGAAGAAATGTAGTTATCAAGTCAGGGGGAAGTTTAATTGGCCAGAAAATATTGATTCCTGGAGAC
ATAAGCTCTGCTTCTTTTTGGATGATTGCTGCATCTATTGTTCCAAATTCAGAGGTTTTAATTCAGAATGTCGGATTAAA
TCCCACTAGAACAGGGATTTTAAATATTATGAATTCAATGGGTTGCAATTATGAGATTTTAGATAAATCGACTATTGCTG
GTGAACCTATTGGATCTATAAAAGTAAAGACTTCAAATAATTTAAAATCATTCATTATTGAAGGAGATATTCTCCCAAAA
CTCATAGATGAAATTCCTATCCTTACTGTGGCTGCTTGTTTTTGTAATGGAGTTTCTGAAATTAAGGATGCACAAGAATT
AAGGGTTAAAGAGACAGATAGATTAAAAGTCATGGCACGACAGTTACAAAAATTCGGTGCTGAAATAACAGAAAAAGAGG
ATGGGTTAATTATTAATGGGCAATCAAAATTTCATTCTGCGGAGGTAGATAGTGAGACAGATCATCGAGTAGCAATGAGT
CTTGCTATTGCTTCACTGCTTGCCAAAGGTACCTCAAAAATCATGAGAGCAGATGCAGCTAGCGTCTCGTATCCCACTTT
TTGGGAAGAGCTTGCCAAACTAACTAACTAG

Upstream 100 bases:

>100_bases
ACAGTTACTTAATTTGATTATTTTTTTTTAAAAACAAACTTATTGATAAGATAGAACTAATTTGTTTTTACAGAAATCTT
ATCAAGTATTTAAATTGAAA

Downstream 100 bases:

>100_bases
CCTAAAAAGTTTTTGTCTGAATTAATAGAAATTTTAACTAAAGATGGTAGTTACTCATTAAGAAGTTTGTTTTTTCAAGA
GAACTTCCATAGTTTATTGG

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MNNIRTIKGGVNLKGKIKVPGDKSISHRALIIGSIAEGETTIEGFLYSEDPLSTADCLRKLGVNIPEIKKDKPFTISGLG
INGLKEPKEILNCGNSGTTMRLLMGLLAGQEGKNFILTGDISLNERPMGRVGKPLSLMGGKIFGREKGNKAPISINGNKL
KGCVMGTPVASAQVKSAILLAGLKASGTTSVIEPASSRDHTERMLKAFGADITIRGEFGRNVVIKSGGSLIGQKILIPGD
ISSASFWMIAASIVPNSEVLIQNVGLNPTRTGILNIMNSMGCNYEILDKSTIAGEPIGSIKVKTSNNLKSFIIEGDILPK
LIDEIPILTVAACFCNGVSEIKDAQELRVKETDRLKVMARQLQKFGAEITEKEDGLIINGQSKFHSAEVDSETDHRVAMS
LAIASLLAKGTSKIMRADAASVSYPTFWEELAKLTN

Sequences:

>Translated_436_residues
MNNIRTIKGGVNLKGKIKVPGDKSISHRALIIGSIAEGETTIEGFLYSEDPLSTADCLRKLGVNIPEIKKDKPFTISGLG
INGLKEPKEILNCGNSGTTMRLLMGLLAGQEGKNFILTGDISLNERPMGRVGKPLSLMGGKIFGREKGNKAPISINGNKL
KGCVMGTPVASAQVKSAILLAGLKASGTTSVIEPASSRDHTERMLKAFGADITIRGEFGRNVVIKSGGSLIGQKILIPGD
ISSASFWMIAASIVPNSEVLIQNVGLNPTRTGILNIMNSMGCNYEILDKSTIAGEPIGSIKVKTSNNLKSFIIEGDILPK
LIDEIPILTVAACFCNGVSEIKDAQELRVKETDRLKVMARQLQKFGAEITEKEDGLIINGQSKFHSAEVDSETDHRVAMS
LAIASLLAKGTSKIMRADAASVSYPTFWEELAKLTN
>Mature_436_residues
MNNIRTIKGGVNLKGKIKVPGDKSISHRALIIGSIAEGETTIEGFLYSEDPLSTADCLRKLGVNIPEIKKDKPFTISGLG
INGLKEPKEILNCGNSGTTMRLLMGLLAGQEGKNFILTGDISLNERPMGRVGKPLSLMGGKIFGREKGNKAPISINGNKL
KGCVMGTPVASAQVKSAILLAGLKASGTTSVIEPASSRDHTERMLKAFGADITIRGEFGRNVVIKSGGSLIGQKILIPGD
ISSASFWMIAASIVPNSEVLIQNVGLNPTRTGILNIMNSMGCNYEILDKSTIAGEPIGSIKVKTSNNLKSFIIEGDILPK
LIDEIPILTVAACFCNGVSEIKDAQELRVKETDRLKVMARQLQKFGAEITEKEDGLIINGQSKFHSAEVDSETDHRVAMS
LAIASLLAKGTSKIMRADAASVSYPTFWEELAKLTN

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family

Homologues:

Organism=Escherichia coli, GI1787137, Length=439, Percent_Identity=28.7015945330296, Blast_Score=136, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6320332, Length=459, Percent_Identity=24.6187363834423, Blast_Score=112, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROA_PROM0 (A3PBY7)

Other databases:

- EMBL:   CP000576
- RefSeq:   YP_001090863.1
- ProteinModelPortal:   A3PBY7
- SMR:   A3PBY7
- STRING:   A3PBY7
- GeneID:   4911126
- GenomeReviews:   CP000576_GR
- KEGG:   pmg:P9301_06391
- eggNOG:   COG0128
- HOGENOM:   HBG646626
- OMA:   LSRNHTE
- ProtClustDB:   PRK02427
- BioCyc:   PMAR167546:P9301ORF_0654-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00210
- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792
- Gene3D:   G3DSA:3.65.10.10
- PIRSF:   PIRSF000505
- TIGRFAMs:   TIGR01356

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.19

Molecular weight: Translated: 46533; Mature: 46533

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: PS00104 EPSP_SYNTHASE_1; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNIRTIKGGVNLKGKIKVPGDKSISHRALIIGSIAEGETTIEGFLYSEDPLSTADCLRK
CCCCEEEECCCCEEEEEECCCCCCCCCEEEEEEECCCCCEEEEEEEECCCCCCHHHHHHH
LGVNIPEIKKDKPFTISGLGINGLKEPKEILNCGNSGTTMRLLMGLLAGQEGKNFILTGD
HCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEEEEC
ISLNERPMGRVGKPLSLMGGKIFGREKGNKAPISINGNKLKGCVMGTPVASAQVKSAILL
CCCCCCCCCCCCCCHHHHCCEEECCCCCCCCCEEECCCEEEEEEECCCCCHHHHHHHHHE
AGLKASGTTSVIEPASSRDHTERMLKAFGADITIRGEFGRNVVIKSGGSLIGQKILIPGD
EECCCCCCCHHCCCCCCCHHHHHHHHHHCCCEEEEECCCCEEEEECCCCCCCCEEEECCC
ISSASFWMIAASIVPNSEVLIQNVGLNPTRTGILNIMNSMGCNYEILDKSTIAGEPIGSI
CCCCEEEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCEE
KVKTSNNLKSFIIEGDILPKLIDEIPILTVAACFCNGVSEIKDAQELRVKETDRLKVMAR
EEEECCCCEEEEEECCHHHHHHHHCHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHH
QLQKFGAEITEKEDGLIINGQSKFHSAEVDSETDHRVAMSLAIASLLAKGTSKIMRADAA
HHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
SVSYPTFWEELAKLTN
CCCCCHHHHHHHHHCC
>Mature Secondary Structure
MNNIRTIKGGVNLKGKIKVPGDKSISHRALIIGSIAEGETTIEGFLYSEDPLSTADCLRK
CCCCEEEECCCCEEEEEECCCCCCCCCEEEEEEECCCCCEEEEEEEECCCCCCHHHHHHH
LGVNIPEIKKDKPFTISGLGINGLKEPKEILNCGNSGTTMRLLMGLLAGQEGKNFILTGD
HCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEEEEC
ISLNERPMGRVGKPLSLMGGKIFGREKGNKAPISINGNKLKGCVMGTPVASAQVKSAILL
CCCCCCCCCCCCCCHHHHCCEEECCCCCCCCCEEECCCEEEEEEECCCCCHHHHHHHHHE
AGLKASGTTSVIEPASSRDHTERMLKAFGADITIRGEFGRNVVIKSGGSLIGQKILIPGD
EECCCCCCCHHCCCCCCCHHHHHHHHHHCCCEEEEECCCCEEEEECCCCCCCCEEEECCC
ISSASFWMIAASIVPNSEVLIQNVGLNPTRTGILNIMNSMGCNYEILDKSTIAGEPIGSI
CCCCEEEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCEE
KVKTSNNLKSFIIEGDILPKLIDEIPILTVAACFCNGVSEIKDAQELRVKETDRLKVMAR
EEEECCCCEEEEEECCHHHHHHHHCHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHH
QLQKFGAEITEKEDGLIINGQSKFHSAEVDSETDHRVAMSLAIASLLAKGTSKIMRADAA
HHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
SVSYPTFWEELAKLTN
CCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA