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The map label for this gene is rhtB [H]

Identifier: 126447122

GI number: 126447122

Start: 900413

End: 901024

Strand: Reverse

Name: rhtB [H]

Synonym: BMA10247_A0949

Alternate gene names: 126447122

Gene position: 901024-900413 (Counterclockwise)

Preceding gene: 126446179

Following gene: 126447888

Centisome position: 38.3

GC content: 68.63

Gene sequence:

>612_bases
ATGTCACTATCCAGCCTCGCCCTCTTCGCCGCCGCCCTGCTGGTCGCCGCCGGCTCGCCCGGCCCGAGCATCGCCGCGCT
GGTCGCGCGCGTGCTGACCAACGGAGTGCGCGACGTGTTGCCGTTCCTCGCGGCGATGTGGCTCGGCGAAGTGATCTGGC
TGACCTGCGCGGTAGCCGGGCTCACGGCGCTCGCGCACACGTTCGCATTCGGCTTTCTCGTGCTGAAGTTCGCGGGCATC
GCCTACCTCGTGTTTCTCGCGTGGAAGATGTGGTTCGCGCCCGCCGATGAGCCGTCCGGCCAGCTCCCGCGCGGACAGTC
GCCGTTGCGCATGTTTCTGACGGGCATCGCGGTCACGCTCGGCAACCCGAAAATCATGATCTTCTATGTCGCGCTGCTGC
CGACGATGGTGGATCTGTCTCGCGCAGGGGCCGTCGCATGGCTCGAATTGACGTTGACGCTGCTCGTCGTGTTGATCACG
GTCGACTGCGCATGGGCATGGCTCGCGGCGCGCGCCCGCAAGCTGCTGACGAGCCGCCGCGCGATGAAGGCGGCGAATCG
CGCGAGCGCGGCCGCGATGGCGGGCGCCGCCGTCGCGATCGCGATGCGCTGA

Upstream 100 bases:

>100_bases
TCACTGGTGAATGGCGCATGGTCGATCGGGTGCGAGCAGCCGTCACTATAATCGATCGTTGACGAACCGATCGTCATCGC
ATCGCCTCGGGAGTTTGAGC

Downstream 100 bases:

>100_bases
CCGGCCGCGCGCCAACACGGCGCGACCACGCGTGGCCAGCCGCACCGGCCGACGCACGTCAAAATGCGCGTGGCGACGCG
TACCCAGCGCCTGCATGGGC

Product: LysE family protein

Products: homoserine lactone [Periplasm]; Proton [Cytoplasm]; homoserine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 203; Mature: 202

Protein sequence:

>203_residues
MSLSSLALFAAALLVAAGSPGPSIAALVARVLTNGVRDVLPFLAAMWLGEVIWLTCAVAGLTALAHTFAFGFLVLKFAGI
AYLVFLAWKMWFAPADEPSGQLPRGQSPLRMFLTGIAVTLGNPKIMIFYVALLPTMVDLSRAGAVAWLELTLTLLVVLIT
VDCAWAWLAARARKLLTSRRAMKAANRASAAAMAGAAVAIAMR

Sequences:

>Translated_203_residues
MSLSSLALFAAALLVAAGSPGPSIAALVARVLTNGVRDVLPFLAAMWLGEVIWLTCAVAGLTALAHTFAFGFLVLKFAGI
AYLVFLAWKMWFAPADEPSGQLPRGQSPLRMFLTGIAVTLGNPKIMIFYVALLPTMVDLSRAGAVAWLELTLTLLVVLIT
VDCAWAWLAARARKLLTSRRAMKAANRASAAAMAGAAVAIAMR
>Mature_202_residues
SLSSLALFAAALLVAAGSPGPSIAALVARVLTNGVRDVLPFLAAMWLGEVIWLTCAVAGLTALAHTFAFGFLVLKFAGIA
YLVFLAWKMWFAPADEPSGQLPRGQSPLRMFLTGIAVTLGNPKIMIFYVALLPTMVDLSRAGAVAWLELTLTLLVVLITV
DCAWAWLAARARKLLTSRRAMKAANRASAAAMAGAAVAIAMR

Specific function: Conducts the efflux of homoserine and homoserine lactone [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994979, Length=169, Percent_Identity=30.1775147928994, Blast_Score=66, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 21429; Mature: 21298

Theoretical pI: Translated: 11.21; Mature: 11.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSSLALFAAALLVAAGSPGPSIAALVARVLTNGVRDVLPFLAAMWLGEVIWLTCAVAG
CCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTALAHTFAFGFLVLKFAGIAYLVFLAWKMWFAPADEPSGQLPRGQSPLRMFLTGIAVTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHC
GNPKIMIFYVALLPTMVDLSRAGAVAWLELTLTLLVVLITVDCAWAWLAARARKLLTSRR
CCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMKAANRASAAAMAGAAVAIAMR
HHHHHHHHHHHHHHHHHHHEECC
>Mature Secondary Structure 
SLSSLALFAAALLVAAGSPGPSIAALVARVLTNGVRDVLPFLAAMWLGEVIWLTCAVAG
CHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTALAHTFAFGFLVLKFAGIAYLVFLAWKMWFAPADEPSGQLPRGQSPLRMFLTGIAVTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHC
GNPKIMIFYVALLPTMVDLSRAGAVAWLELTLTLLVVLITVDCAWAWLAARARKLLTSRR
CCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMKAANRASAAAMAGAAVAIAMR
HHHHHHHHHHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; homoserine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + homoserine lactone [Cytoplasm] = Proton [Cytoplasm] + homoserine lactone [Periplasm] Proton [Periplasm] + homoserine [Cytoplasm] = Proton [Cytoplasm] + homoserine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]