BacMap

Definition	Burkholderia mallei NCTC 10247 chromosome II, complete genome.
Accession	NC_009079
Length	2,352,693

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The map label for this gene is paaG [H]

Identifier: 126446349

GI number: 126446349

Start: 1835329

End: 1836120

Strand: Direct

Name: paaG [H]

Synonym: BMA10247_A1903

Alternate gene names: 126446349

Gene position: 1835329-1836120 (Clockwise)

Preceding gene: 126445826

Following gene: 126446935

Centisome position: 78.01

GC content: 66.29

Gene sequence:

>792_bases
ATGTCCTACCAGACGATTCGCATCGAAATCGATCAGGCGGCACAGATCGCGACGATCACGCTCGATCGCCCCGACAAGCT
CAACAGCTTCACGCGCGACATGCATCGCGAACTGCAGTCGGCGCTCGACGACGTGCAGGCCGCGAACGCACGCGCCCTGG
TTCTCACCGGCGCAGGACGCGGCTTCTGCGCAGGCCAGGATCTCGCCGATCTCGACTTCACGCCGGGGGCGATGACCGAT
CTCGGCGAGGTGATCGAAGCGCATTTCAATCCGCTCGTTCGCCGCCTGCAAGCGCTGCCGCTGCCCGTCATCGCCGCCGT
GAACGGCACCGCGGCGGGCGCCGGCGCCAACCTCGCGTTCGCCTGCGATCTCGTCATCGCGGCGAAATCGAGCAGCTTCA
TTCAGTCGTTCGTGAAAATCGGCCTCGTTCCGGATTCCGGCGGCACGTGGTTCCTGCCGCAGCGCGTCGGCTTCGCCCGT
GCGCTCGGGCTCGCACTGACCGGCGACAAACTGAGTGCCGAACAAGCCGAGCGTTGGGGACTCGTGTGGCGGGTCGTCGA
CGATGCCGAACTCGCGGGCGCCGCCGCACAACTCGCCCGAGAACTTGCGCAACAGCCGACGCGGGCGATCGCGGCGATCA
AGCAGGCGATGCGTGCGAGCCTCACCCATACGCTCGACCAGCAGCTCGATCTCGAACGCGATCTTCAGCGCGAGCTCGGG
CAATCGTACGACTACGCGGAAGGGGTGCGCGCGTTCATCGAAAAGCGCGCCCCTCGCTTCGAAGGACGCTGA

Upstream 100 bases:

>100_bases
GGCGTCGGCCAGGGCATCGCGATCGCGATCGAGCGCGTATAAGCCGGCCCGCGGACGAAGGACGCATCCCGTTCATTTCG
AAGAGGCAAGGAGACAGCCG

Downstream 100 bases:

>100_bases
GATGGCCGCACGCTCTCCCGAACGCTCGCCAACGGCGACCGCAGAACGCTCCGCCGAAGCGCTCGCCCGCGCAACCGCCG
AAGCAATGTACGCCGCGGAC

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 262

Protein sequence:

>263_residues
MSYQTIRIEIDQAAQIATITLDRPDKLNSFTRDMHRELQSALDDVQAANARALVLTGAGRGFCAGQDLADLDFTPGAMTD
LGEVIEAHFNPLVRRLQALPLPVIAAVNGTAAGAGANLAFACDLVIAAKSSSFIQSFVKIGLVPDSGGTWFLPQRVGFAR
ALGLALTGDKLSAEQAERWGLVWRVVDDAELAGAAAQLARELAQQPTRAIAAIKQAMRASLTHTLDQQLDLERDLQRELG
QSYDYAEGVRAFIEKRAPRFEGR

Sequences:

>Translated_263_residues
MSYQTIRIEIDQAAQIATITLDRPDKLNSFTRDMHRELQSALDDVQAANARALVLTGAGRGFCAGQDLADLDFTPGAMTD
LGEVIEAHFNPLVRRLQALPLPVIAAVNGTAAGAGANLAFACDLVIAAKSSSFIQSFVKIGLVPDSGGTWFLPQRVGFAR
ALGLALTGDKLSAEQAERWGLVWRVVDDAELAGAAAQLARELAQQPTRAIAAIKQAMRASLTHTLDQQLDLERDLQRELG
QSYDYAEGVRAFIEKRAPRFEGR
>Mature_262_residues
SYQTIRIEIDQAAQIATITLDRPDKLNSFTRDMHRELQSALDDVQAANARALVLTGAGRGFCAGQDLADLDFTPGAMTDL
GEVIEAHFNPLVRRLQALPLPVIAAVNGTAAGAGANLAFACDLVIAAKSSSFIQSFVKIGLVPDSGGTWFLPQRVGFARA
LGLALTGDKLSAEQAERWGLVWRVVDDAELAGAAAQLARELAQQPTRAIAAIKQAMRASLTHTLDQQLDLERDLQRELGQ
SYDYAEGVRAFIEKRAPRFEGR

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=247, Percent_Identity=33.1983805668016, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI70995211, Length=266, Percent_Identity=29.6992481203008, Blast_Score=101, Evalue=8e-22,
Organism=Homo sapiens, GI31542718, Length=261, Percent_Identity=28.735632183908, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI45643119, Length=204, Percent_Identity=27.9411764705882, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI260275230, Length=204, Percent_Identity=27.9411764705882, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI260274832, Length=204, Percent_Identity=27.9411764705882, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI4502327, Length=260, Percent_Identity=28.8461538461538, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI221136756, Length=238, Percent_Identity=26.4705882352941, Blast_Score=84, Evalue=9e-17,
Organism=Homo sapiens, GI221136753, Length=238, Percent_Identity=26.4705882352941, Blast_Score=84, Evalue=9e-17,
Organism=Homo sapiens, GI221307494, Length=238, Percent_Identity=26.4705882352941, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI20127408, Length=179, Percent_Identity=30.7262569832402, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI25453481, Length=243, Percent_Identity=23.8683127572016, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI51538573, Length=243, Percent_Identity=23.8683127572016, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI4757968, Length=243, Percent_Identity=23.8683127572016, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI49355787, Length=243, Percent_Identity=23.8683127572016, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI157694516, Length=224, Percent_Identity=27.2321428571429, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI213417737, Length=224, Percent_Identity=27.2321428571429, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI37594469, Length=190, Percent_Identity=31.0526315789474, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI37594471, Length=190, Percent_Identity=31.0526315789474, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI4757966, Length=237, Percent_Identity=24.0506329113924, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI51538581, Length=237, Percent_Identity=24.0506329113924, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI116235487, Length=231, Percent_Identity=23.8095238095238, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI68989263, Length=179, Percent_Identity=29.608938547486, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI157694520, Length=205, Percent_Identity=26.8292682926829, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1787660, Length=250, Percent_Identity=58, Blast_Score=263, Evalue=8e-72,
Organism=Escherichia coli, GI1787659, Length=258, Percent_Identity=35.2713178294574, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI221142681, Length=274, Percent_Identity=37.2262773722628, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI87082183, Length=271, Percent_Identity=29.520295202952, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI1788597, Length=262, Percent_Identity=31.2977099236641, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1788682, Length=202, Percent_Identity=31.6831683168317, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI1790281, Length=189, Percent_Identity=29.6296296296296, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI25145438, Length=249, Percent_Identity=34.5381526104418, Blast_Score=143, Evalue=7e-35,
Organism=Caenorhabditis elegans, GI17554946, Length=262, Percent_Identity=31.2977099236641, Blast_Score=128, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17549921, Length=233, Percent_Identity=28.3261802575107, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17535521, Length=257, Percent_Identity=27.2373540856031, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17536985, Length=266, Percent_Identity=27.0676691729323, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17560910, Length=253, Percent_Identity=26.4822134387352, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17540306, Length=260, Percent_Identity=30.7692307692308, Blast_Score=94, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17534483, Length=225, Percent_Identity=26.2222222222222, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17540714, Length=175, Percent_Identity=30.8571428571429, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI25144276, Length=184, Percent_Identity=29.8913043478261, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17508951, Length=184, Percent_Identity=29.8913043478261, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17508953, Length=184, Percent_Identity=29.8913043478261, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17558304, Length=227, Percent_Identity=27.3127753303965, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI25141363, Length=204, Percent_Identity=30.3921568627451, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI20129971, Length=261, Percent_Identity=30.6513409961686, Blast_Score=135, Evalue=4e-32,
Organism=Drosophila melanogaster, GI24653477, Length=261, Percent_Identity=30.6513409961686, Blast_Score=135, Evalue=4e-32,
Organism=Drosophila melanogaster, GI24653139, Length=261, Percent_Identity=32.9501915708812, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI19922422, Length=250, Percent_Identity=28, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24654903, Length=256, Percent_Identity=25.78125, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI19920382, Length=252, Percent_Identity=30.5555555555556, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI21357171, Length=257, Percent_Identity=28.0155642023346, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24650670, Length=217, Percent_Identity=29.0322580645161, Blast_Score=76, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR011968 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 28401; Mature: 28269

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYQTIRIEIDQAAQIATITLDRPDKLNSFTRDMHRELQSALDDVQAANARALVLTGAGR
CCCEEEEEEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
GFCAGQDLADLDFTPGAMTDLGEVIEAHFNPLVRRLQALPLPVIAAVNGTAAGAGANLAF
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHH
ACDLVIAAKSSSFIQSFVKIGLVPDSGGTWFLPQRVGFARALGLALTGDKLSAEQAERWG
EEHHHEECCCHHHHHHHHHHCCEECCCCCEECHHHHHHHHHHHHHCCCCCCCHHHHHHCC
LVWRVVDDAELAGAAAQLARELAQQPTRAIAAIKQAMRASLTHTLDQQLDLERDLQRELG
EEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHC
QSYDYAEGVRAFIEKRAPRFEGR
CCCCHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SYQTIRIEIDQAAQIATITLDRPDKLNSFTRDMHRELQSALDDVQAANARALVLTGAGR
CCEEEEEEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
GFCAGQDLADLDFTPGAMTDLGEVIEAHFNPLVRRLQALPLPVIAAVNGTAAGAGANLAF
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHH
ACDLVIAAKSSSFIQSFVKIGLVPDSGGTWFLPQRVGFARALGLALTGDKLSAEQAERWG
EEHHHEECCCHHHHHHHHHHCCEECCCCCEECHHHHHHHHHHHHHCCCCCCCHHHHHHCC
LVWRVVDDAELAGAAAQLARELAQQPTRAIAAIKQAMRASLTHTLDQQLDLERDLQRELG
EEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHC
QSYDYAEGVRAFIEKRAPRFEGR
CCCCHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9748275; 9097039; 9278503; 10766858 [H]