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The map label for this gene is abgR [H]

Identifier: 126443064

GI number: 126443064

Start: 431910

End: 432809

Strand: Reverse

Name: abgR [H]

Synonym: BURPS668_A0475

Alternate gene names: 126443064

Gene position: 432809-431910 (Counterclockwise)

Preceding gene: 126442714

Following gene: 126445539

Centisome position: 13.84

GC content: 71.44

Gene sequence:

>900_bases
ATGAAGCTCCAGCAACTGCAGGCGTTCGTCTGCGCCGCCCATCACAAGAGCCTGCGCGCCGCCGCGCGCGCGCTCGGCGT
CACGCAGCCCGCGATCACACATACCATCCGCGAGCTCGAGGCCGCGCTCAACGCGGAACTGCTCGTGCGCAGCGTGCGCG
GCGTCGAGCTGACCGCGTGCGGCCATGCGCTGCTGCCGCGCGCCGAGCAACTGCTCGGCGACATGCGCCGCACCGTCGAG
GCGGTCGAGCAGGTGCGCGGCGAGCTCTCCGGGCGCGTCGCGATCGGCACGATGCCGTCGATCGCGCTCACCGCGCTGCC
GCGCGCGGTGATGAAGTTCCGCGCGACGATGCCGCACGTGAGCCTGTCGCTCGAAGAGGTGACGGTGCCCAACGCGCTCG
CGCGGCTGCGCAACGGCGAGCTCGACATCGCGGCGATCCACCACATTCCCGCGCTCGAGCGCGACTTCGCGCAACTGCCG
CTGTGCTCGACGGAATTCGTCGTCGCGATGCGCGAAGGCCATCCGCTCGCGGGTGCGCGGCGGCTCGCCGAGCTGCTCGA
CGCCGAGTGGATCGTCACGGTCGGCGCCGATCACTTCCCGCACAGCGTGATGATGTCGATGTTCAACGCGCACGGGCTGC
CGCTGCCGCAGCGGCTGCTGCGCGCGCCGTCGTCGTTCGCGGTGACGCTCGGCCTCGTCGCGCGCTCGGACGTGATCGGC
TGCTTCACGAAGCCGCTCGCGGCGATGGTCGCGCCGCTCGGCATCCGCCCCGCGCGTCTCGACGACAGGCTGCCGAGCTA
CGACCTGTCGATCCTGTCGCGCCGCGACCTGCTGCCGACGCCCGCCGTCACGCAGTTCATCGCGTGCCTGCGGCAGGCAG
CCGACGAAACGTTGACGTAA

Upstream 100 bases:

>100_bases
GACGCGCAGGAGGGGGCACTATAGCGACGCCATAACGATTCAATAAGATGCCGTTTTTTTCACCGCGATAAACTGCGTTT
ATCATCCCGCCCTCGCCGCC

Downstream 100 bases:

>100_bases
ATCATTCCCGGACCGGCAACGGCTGGGCGCGCCGCGCAAACCGCCGCGGCGCTCGGCCGATCGCTATCGGGGCTTCTACT
AAGCAGCCTCGGCCTATTTT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MKLQQLQAFVCAAHHKSLRAAARALGVTQPAITHTIRELEAALNAELLVRSVRGVELTACGHALLPRAEQLLGDMRRTVE
AVEQVRGELSGRVAIGTMPSIALTALPRAVMKFRATMPHVSLSLEEVTVPNALARLRNGELDIAAIHHIPALERDFAQLP
LCSTEFVVAMREGHPLAGARRLAELLDAEWIVTVGADHFPHSVMMSMFNAHGLPLPQRLLRAPSSFAVTLGLVARSDVIG
CFTKPLAAMVAPLGIRPARLDDRLPSYDLSILSRRDLLPTPAVTQFIACLRQAADETLT

Sequences:

>Translated_299_residues
MKLQQLQAFVCAAHHKSLRAAARALGVTQPAITHTIRELEAALNAELLVRSVRGVELTACGHALLPRAEQLLGDMRRTVE
AVEQVRGELSGRVAIGTMPSIALTALPRAVMKFRATMPHVSLSLEEVTVPNALARLRNGELDIAAIHHIPALERDFAQLP
LCSTEFVVAMREGHPLAGARRLAELLDAEWIVTVGADHFPHSVMMSMFNAHGLPLPQRLLRAPSSFAVTLGLVARSDVIG
CFTKPLAAMVAPLGIRPARLDDRLPSYDLSILSRRDLLPTPAVTQFIACLRQAADETLT
>Mature_299_residues
MKLQQLQAFVCAAHHKSLRAAARALGVTQPAITHTIRELEAALNAELLVRSVRGVELTACGHALLPRAEQLLGDMRRTVE
AVEQVRGELSGRVAIGTMPSIALTALPRAVMKFRATMPHVSLSLEEVTVPNALARLRNGELDIAAIHHIPALERDFAQLP
LCSTEFVVAMREGHPLAGARRLAELLDAEWIVTVGADHFPHSVMMSMFNAHGLPLPQRLLRAPSSFAVTLGLVARSDVIG
CFTKPLAAMVAPLGIRPARLDDRLPSYDLSILSRRDLLPTPAVTQFIACLRQAADETLT

Specific function: Could be the regulator of the abg operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787601, Length=295, Percent_Identity=29.4915254237288, Blast_Score=131, Evalue=6e-32,
Organism=Escherichia coli, GI145693105, Length=304, Percent_Identity=27.6315789473684, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1789506, Length=258, Percent_Identity=27.1317829457364, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1790399, Length=178, Percent_Identity=30.3370786516854, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1788887, Length=186, Percent_Identity=30.6451612903226, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87081904, Length=144, Percent_Identity=30.5555555555556, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788297, Length=152, Percent_Identity=33.5526315789474, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI2367136, Length=294, Percent_Identity=28.2312925170068, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI157672245, Length=208, Percent_Identity=27.4038461538462, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787530, Length=220, Percent_Identity=27.7272727272727, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788706, Length=176, Percent_Identity=30.1136363636364, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1788748, Length=144, Percent_Identity=28.4722222222222, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1788296, Length=146, Percent_Identity=32.8767123287671, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32427; Mature: 32427

Theoretical pI: Translated: 8.53; Mature: 8.53

Prosite motif: PS50931 HTH_LYSR ; PS00290 IG_MHC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLQQLQAFVCAAHHKSLRAAARALGVTQPAITHTIRELEAALNAELLVRSVRGVELTAC
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECC
GHALLPRAEQLLGDMRRTVEAVEQVRGELSGRVAIGTMPSIALTALPRAVMKFRATMPHV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHCCCC
SLSLEEVTVPNALARLRNGELDIAAIHHIPALERDFAQLPLCSTEFVVAMREGHPLAGAR
EEEHHHHHHHHHHHHHCCCCCEEEHHHHCCHHHHHHHHCCCCCHHHHEEECCCCCCHHHH
RLAELLDAEWIVTVGADHFPHSVMMSMFNAHGLPLPQRLLRAPSSFAVTLGLVARSDVIG
HHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHH
CFTKPLAAMVAPLGIRPARLDDRLPSYDLSILSRRDLLPTPAVTQFIACLRQAADETLT
HHHHHHHHHHHCCCCCCCCHHCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKLQQLQAFVCAAHHKSLRAAARALGVTQPAITHTIRELEAALNAELLVRSVRGVELTAC
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECC
GHALLPRAEQLLGDMRRTVEAVEQVRGELSGRVAIGTMPSIALTALPRAVMKFRATMPHV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHCCCC
SLSLEEVTVPNALARLRNGELDIAAIHHIPALERDFAQLPLCSTEFVVAMREGHPLAGAR
EEEHHHHHHHHHHHHHCCCCCEEEHHHHCCHHHHHHHHCCCCCHHHHEEECCCCCCHHHH
RLAELLDAEWIVTVGADHFPHSVMMSMFNAHGLPLPQRLLRAPSSFAVTLGLVARSDVIG
HHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHH
CFTKPLAAMVAPLGIRPARLDDRLPSYDLSILSRRDLLPTPAVTQFIACLRQAADETLT
HHHHHHHHHHHCCCCCCCCHHCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 9829935 [H]