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The map label for this gene is clpP2 [H]

Identifier: 126207994

GI number: 126207994

Start: 579501

End: 581525

Strand: Direct

Name: clpP2 [H]

Synonym: APL_0510

Alternate gene names: 126207994

Gene position: 579501-581525 (Clockwise)

Preceding gene: 126207993

Following gene: 126207995

Centisome position: 25.48

GC content: 45.43

Gene sequence:

>2025_bases
ATGAGAAAAAAACAAATGGTTCTAGCCCCGATGGCGAAGGCAGTAGCAGTAACCAAGACGAATAATCAGTCTTGGTTTAC
GATTAAAGCTGCGGCCAACGACACCGCAGAGATTAGCATTTATGATGAAATCGGTTTTTGGGGTGTTACAGCCCAACAGT
TTGCCAACGATTTAAAAGCCCTTGGAAACAATCTCAAACAGATCAATCTGCATATCCACTCGCCCGGAGGCGATGTGTTT
GATGGTATTGCCATCTACAATTTGCTGAAAAATCACCCTGCTAACAAGACCGTCTATATCGACGGTCTTGCTGCATCTAT
GGCTTCAGTTATTGCAATGGCTGGTAACGAAATCATTATGCCCGAAAACGCAATGATGATGATCCACAAGCCGTGGGGAA
TCCAAGGCGGTGATGCTGATGATATGCGGAAATATGCGGATTTGCTTGATAAGGTCGAAAGTACCCTGATTATGGCCTAT
GTCGCTAAAACAGAAAAATCCGAAGAAGAATTAGCAGAAATGCTGAAAGAAGAAACTTGGCTCACAGGCAAAGAGTGCGT
GGAGCAAGGTTTCGCCGATAAGTTAGCCGAACCCCTTGTGGCGATGGCTTGTATCCAATCCAAAAAATTAGAGGACTACA
CAAAAATGCCTGACAAAATCAAAAATATGCTATTCGCACCACAAGGCAACGCAGGTGCAAATCCAAAACCTGAACAACCT
CAAACACCACCACAAGCGGGTGAAAATCCGCAAAATGTGGCAAAACCTGATGCAATGGTGGCATTAGCCCAACGCAATGC
AACGATTAAAGCGACCTTTGCCGCTTTCGGCACACAATTTGACGGCTTACTGGCAGAATGTTTAGCTGATGTGTCAATGA
CCGCTGAGCAAGCCAAAGACAAGCTCCTTGCCAAACTGGGCGAAAACACCACCCCAAGCGTACCGCAAAACCACATTCAC
GCAGGTAACGGTAACATCGTTGGCGACAGCGTGAAGCAGTCGTTAATGGCTCGTGCTGGTCAAGATACCGACAAAACCAA
CGCAAGAGATAATACCTACAATGCAATGACCTTGCGTGAGTTGGCTCGTGCCTCATTGGTTGATCGTGGCGTGGGTATTG
CGGGCTACACCCCAATGCAGATGGTCGGTCTTGCCTTTACGCACTCAAGTTCTGATTTCGGTCAAATCTTAATTGATGTA
GCACATAAATCCTTGCTAAAAGGCTGGGAAGTATCAAACGAAAATTACGAACAATTTACCTCACGCGGTATTTTAACCGA
CTTCCGTCCGGCTAAACGTGTTGGCTTAGGGGAATTTGGCTACTTACCAACCGTGGGTGAGGGTGAAGAATACACCTATG
GTACACTCGGTGATGAAGGCGCATCTATCGCACTCGCTACCTACGGGCAATTATTTAGCATTACCCGTCAGGCGATCATC
AATGATGATATGCACCTCTTGACCACCATTCCTCAAAAAATGGGGCAAGCGGCACGTGCAACCATCGCAAAATTGGTATT
TGCCTTGATTACAGGTAATGCAACTGCTCAAGATGGCAAAAAATTGTTTGACGCAAGTCATAAAAACAGCCTCACAGGGG
CAAAATTGGACGTTGAACATATCGATAAAGCGGTGCAATTGATGAATGGTTTTGTAAACAGCCGTGGTGAACCATTAGCG
ATTGAGCCAGAATTTATGTTGCTCCCAACCTCGCTACATACCAAAGCGAAGCAGATCTTAGGCTCATCAAGTGTCGAAGG
AGCAGACATCAACAGCGGTATCATTAACCCAATCCGTGATATTGTTAGCCCGATTAAATCGCCACGTTTACAGATTGCCG
ATGCGAAATCGTGGTATCTCATCAACAAAGAAGCTATTGAAGTTTCTTATCTTGATGGTGTAGATAGCCCGTATATCGAA
CAGCAACAAGGCTTCTCGGTAGATGGTGTTACCACAAAAGTTCGCATTGATGCCGGCGTAAATGTGATTGATTATCGTGG
TATTGTGAAAGTCACAAACCAGTAA

Upstream 100 bases:

>100_bases
CCAGCCGAAGTCAAACGGCAACGAATTGTCGAGATCAAAGAGAATGCTCGTGAGGGCTTGAAATTTGATACTGATTTAAC
CAACACGCAAGGAATTAGTA

Downstream 100 bases:

>100_bases
CTAGCAAATAACTTATAGACCGTACTTTAATCAATAAGGTACGGTTTTTTATTATCTGAAAAAGGAAAACCTTATGGCTA
AAAACTATATTCAGGATGGT

Product: putative Clp-like protease

Products: NA

Alternate protein names: Endopeptidase Clp 2 [H]

Number of amino acids: Translated: 674; Mature: 674

Protein sequence:

>674_residues
MRKKQMVLAPMAKAVAVTKTNNQSWFTIKAAANDTAEISIYDEIGFWGVTAQQFANDLKALGNNLKQINLHIHSPGGDVF
DGIAIYNLLKNHPANKTVYIDGLAASMASVIAMAGNEIIMPENAMMMIHKPWGIQGGDADDMRKYADLLDKVESTLIMAY
VAKTEKSEEELAEMLKEETWLTGKECVEQGFADKLAEPLVAMACIQSKKLEDYTKMPDKIKNMLFAPQGNAGANPKPEQP
QTPPQAGENPQNVAKPDAMVALAQRNATIKATFAAFGTQFDGLLAECLADVSMTAEQAKDKLLAKLGENTTPSVPQNHIH
AGNGNIVGDSVKQSLMARAGQDTDKTNARDNTYNAMTLRELARASLVDRGVGIAGYTPMQMVGLAFTHSSSDFGQILIDV
AHKSLLKGWEVSNENYEQFTSRGILTDFRPAKRVGLGEFGYLPTVGEGEEYTYGTLGDEGASIALATYGQLFSITRQAII
NDDMHLLTTIPQKMGQAARATIAKLVFALITGNATAQDGKKLFDASHKNSLTGAKLDVEHIDKAVQLMNGFVNSRGEPLA
IEPEFMLLPTSLHTKAKQILGSSSVEGADINSGIINPIRDIVSPIKSPRLQIADAKSWYLINKEAIEVSYLDGVDSPYIE
QQQGFSVDGVTTKVRIDAGVNVIDYRGIVKVTNQ

Sequences:

>Translated_674_residues
MRKKQMVLAPMAKAVAVTKTNNQSWFTIKAAANDTAEISIYDEIGFWGVTAQQFANDLKALGNNLKQINLHIHSPGGDVF
DGIAIYNLLKNHPANKTVYIDGLAASMASVIAMAGNEIIMPENAMMMIHKPWGIQGGDADDMRKYADLLDKVESTLIMAY
VAKTEKSEEELAEMLKEETWLTGKECVEQGFADKLAEPLVAMACIQSKKLEDYTKMPDKIKNMLFAPQGNAGANPKPEQP
QTPPQAGENPQNVAKPDAMVALAQRNATIKATFAAFGTQFDGLLAECLADVSMTAEQAKDKLLAKLGENTTPSVPQNHIH
AGNGNIVGDSVKQSLMARAGQDTDKTNARDNTYNAMTLRELARASLVDRGVGIAGYTPMQMVGLAFTHSSSDFGQILIDV
AHKSLLKGWEVSNENYEQFTSRGILTDFRPAKRVGLGEFGYLPTVGEGEEYTYGTLGDEGASIALATYGQLFSITRQAII
NDDMHLLTTIPQKMGQAARATIAKLVFALITGNATAQDGKKLFDASHKNSLTGAKLDVEHIDKAVQLMNGFVNSRGEPLA
IEPEFMLLPTSLHTKAKQILGSSSVEGADINSGIINPIRDIVSPIKSPRLQIADAKSWYLINKEAIEVSYLDGVDSPYIE
QQQGFSVDGVTTKVRIDAGVNVIDYRGIVKVTNQ
>Mature_674_residues
MRKKQMVLAPMAKAVAVTKTNNQSWFTIKAAANDTAEISIYDEIGFWGVTAQQFANDLKALGNNLKQINLHIHSPGGDVF
DGIAIYNLLKNHPANKTVYIDGLAASMASVIAMAGNEIIMPENAMMMIHKPWGIQGGDADDMRKYADLLDKVESTLIMAY
VAKTEKSEEELAEMLKEETWLTGKECVEQGFADKLAEPLVAMACIQSKKLEDYTKMPDKIKNMLFAPQGNAGANPKPEQP
QTPPQAGENPQNVAKPDAMVALAQRNATIKATFAAFGTQFDGLLAECLADVSMTAEQAKDKLLAKLGENTTPSVPQNHIH
AGNGNIVGDSVKQSLMARAGQDTDKTNARDNTYNAMTLRELARASLVDRGVGIAGYTPMQMVGLAFTHSSSDFGQILIDV
AHKSLLKGWEVSNENYEQFTSRGILTDFRPAKRVGLGEFGYLPTVGEGEEYTYGTLGDEGASIALATYGQLFSITRQAII
NDDMHLLTTIPQKMGQAARATIAKLVFALITGNATAQDGKKLFDASHKNSLTGAKLDVEHIDKAVQLMNGFVNSRGEPLA
IEPEFMLLPTSLHTKAKQILGSSSVEGADINSGIINPIRDIVSPIKSPRLQIADAKSWYLINKEAIEVSYLDGVDSPYIE
QQQGFSVDGVTTKVRIDAGVNVIDYRGIVKVTNQ

Specific function: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S14 family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17538017, Length=133, Percent_Identity=29.3233082706767, Blast_Score=67, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001907
- InterPro:   IPR018215 [H]

Pfam domain/function: PF00574 CLP_protease [H]

EC number: =3.4.21.92 [H]

Molecular weight: Translated: 73046; Mature: 73046

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKKQMVLAPMAKAVAVTKTNNQSWFTIKAAANDTAEISIYDEIGFWGVTAQQFANDLKA
CCCCHHHHHHHHHEEEEEECCCCEEEEEEECCCCCEEEEEEECCCCCCCCHHHHHHHHHH
LGNNLKQINLHIHSPGGDVFDGIAIYNLLKNHPANKTVYIDGLAASMASVIAMAGNEIIM
HCCCEEEEEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHCCCEEEC
PENAMMMIHKPWGIQGGDADDMRKYADLLDKVESTLIMAYVAKTEKSEEELAEMLKEETW
CCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC
LTGKECVEQGFADKLAEPLVAMACIQSKKLEDYTKMPDKIKNMLFAPQGNAGANPKPEQP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHEECCCCCCCCCCCCCCC
QTPPQAGENPQNVAKPDAMVALAQRNATIKATFAAFGTQFDGLLAECLADVSMTAEQAKD
CCCCCCCCCCHHCCCCHHHHHHHHCCCEEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
KLLAKLGENTTPSVPQNHIHAGNGNIVGDSVKQSLMARAGQDTDKTNARDNTYNAMTLRE
HHHHHHCCCCCCCCCCCCEECCCCCEECHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHH
LARASLVDRGVGIAGYTPMQMVGLAFTHSSSDFGQILIDVAHKSLLKGWEVSNENYEQFT
HHHHHHHHCCCCCCCCCHHHHHHEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
SRGILTDFRPAKRVGLGEFGYLPTVGEGEEYTYGTLGDEGASIALATYGQLFSITRQAII
HCCCCCCCCHHHHCCCCCCCCCCCCCCCCCEEECCCCCCCCEEEEHHHHHHHHHHHHHHH
NDDMHLLTTIPQKMGQAARATIAKLVFALITGNATAQDGKKLFDASHKNSLTGAKLDVEH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCEECHHH
IDKAVQLMNGFVNSRGEPLAIEPEFMLLPTSLHTKAKQILGSSSVEGADINSGIINPIRD
HHHHHHHHHHHHHCCCCCEEECCCEEEECCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHH
IVSPIKSPRLQIADAKSWYLINKEAIEVSYLDGVDSPYIEQQQGFSVDGVTTKVRIDAGV
HHHHHCCCCEEEECCCEEEEEECCEEEEEEECCCCCCCCHHHCCCCCCCCEEEEEECCCC
NVIDYRGIVKVTNQ
CEEECCCEEEECCC
>Mature Secondary Structure
MRKKQMVLAPMAKAVAVTKTNNQSWFTIKAAANDTAEISIYDEIGFWGVTAQQFANDLKA
CCCCHHHHHHHHHEEEEEECCCCEEEEEEECCCCCEEEEEEECCCCCCCCHHHHHHHHHH
LGNNLKQINLHIHSPGGDVFDGIAIYNLLKNHPANKTVYIDGLAASMASVIAMAGNEIIM
HCCCEEEEEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHCCCEEEC
PENAMMMIHKPWGIQGGDADDMRKYADLLDKVESTLIMAYVAKTEKSEEELAEMLKEETW
CCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC
LTGKECVEQGFADKLAEPLVAMACIQSKKLEDYTKMPDKIKNMLFAPQGNAGANPKPEQP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHEECCCCCCCCCCCCCCC
QTPPQAGENPQNVAKPDAMVALAQRNATIKATFAAFGTQFDGLLAECLADVSMTAEQAKD
CCCCCCCCCCHHCCCCHHHHHHHHCCCEEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
KLLAKLGENTTPSVPQNHIHAGNGNIVGDSVKQSLMARAGQDTDKTNARDNTYNAMTLRE
HHHHHHCCCCCCCCCCCCEECCCCCEECHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHH
LARASLVDRGVGIAGYTPMQMVGLAFTHSSSDFGQILIDVAHKSLLKGWEVSNENYEQFT
HHHHHHHHCCCCCCCCCHHHHHHEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
SRGILTDFRPAKRVGLGEFGYLPTVGEGEEYTYGTLGDEGASIALATYGQLFSITRQAII
HCCCCCCCCHHHHCCCCCCCCCCCCCCCCCEEECCCCCCCCEEEEHHHHHHHHHHHHHHH
NDDMHLLTTIPQKMGQAARATIAKLVFALITGNATAQDGKKLFDASHKNSLTGAKLDVEH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCEECHHH
IDKAVQLMNGFVNSRGEPLAIEPEFMLLPTSLHTKAKQILGSSSVEGADINSGIINPIRD
HHHHHHHHHHHHHCCCCCEEECCCEEEECCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHH
IVSPIKSPRLQIADAKSWYLINKEAIEVSYLDGVDSPYIEQQQGFSVDGVTTKVRIDAGV
HHHHHCCCCEEEECCCEEEEEECCEEEEEEECCCCCCCCHHHCCCCCCCCEEEEEECCCC
NVIDYRGIVKVTNQ
CEEECCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]