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The map label for this gene is glpT [H]

Identifier: 126207861

GI number: 126207861

Start: 428217

End: 429662

Strand: Reverse

Name: glpT [H]

Synonym: APL_0377

Alternate gene names: 126207861

Gene position: 429662-428217 (Counterclockwise)

Preceding gene: 126207862

Following gene: 126207860

Centisome position: 18.89

GC content: 43.91

Gene sequence:

>1446_bases
ATGTTTGGTCCATTCAAACCGGCTCCGCATATTGCGGAATTACCGGCAGATAAAATAGATGCCAGATACAAATTCTTACG
TTGGCAAGTTTTTGCAGGTATCTTTTTCGGCTATGCCGCCTATTACTTTGTGCGTGCGAACTTCGATCTTGCGCAAAAAG
GTTTAATCGAAGCGGGTTTATATAATAAAGCGGAACTCGGTATTATCGGTACCGGTGCGGGTTTGGCTTACGGTTTATCT
AAATTCGTAATGGCGGGTATGTCAGACCGCTCGAATCCGAAAGTATTTTTACCGTTCGGTTTATTACTTTCCGGTCTTTG
TATGACGATGATGGGCTTAATGCCGTGGGCGACTTCAGGTATTGCAGTGATGTTCATCATGATTTTCTTAAACGGTTGGT
TCCAAGGTATGGGTTGGCCACCGTGCGGTCGTACCATGGTTCACTGGTGGTCTAAATCCGAACGCGGTACTATCGTTTCT
ATTTGGAACTGTGCGCATAACGTGGGCGGTATGGTACCGGGTGCGATGGTATTATTAGCCAGTACGATTTACTTCAGCAA
CACCGGCGAACACGCTACAGCGAAAGACGTATGGCAACAAGCCCTTTACTATCCGGGTATTGCCGCAATGATCGCTGCGA
TTCCGGTTTATTTCGTGATGAAAGATACACCGCAATCTTGCGGTTTACCGCCGGTAGAAAAATGGCGTAACGACTATCCG
GATGATTATAATGAAGAAACGGCGGAAAAAGACTTAAGTACCAAAGAAATCTTTGTGACTTACGTACTTAAAAACAAATT
ATTATGGTACATCGCAATCGCTAACGTATTCGTGTATTTAATCCGTTACGGCGTATTAAAATGGTCTCCGGTTTATCTTG
GTGAAGTAAAACACTTTAACATTAAAGGAACTGCATGGGCTTATACCATTTATGAATTAGCTGCGATTCCGGGTACATTA
TTATGCGGTTGGGTATCGGATAAATTATTCAAAGGTAAACGCGGTTTAACCGGCTTTATCTTCATGATCTTAACGACTAT
CGCCGTGTTCGCATTATGGAAAAACCCGGCAACGCCTGAAGCGGAATTAGCGCAATATGCAGGTAAAGCGTGGTATGAAA
ACCCATATCAATTAATGGACTTCATCTTAATGACAACTATCGGTTTCTTAATCTATGGTCCGGTAATGTTAATCGGTTTA
CACGCACTTGAACTTGCACCGAAAAAAGCGGCGGGTACTTCAGCGGGCTTTACCGGTTTATTCGGTTACTTAGGCGGTAC
TGTTTCGGCATCGGCCGTTGTAGGTTGGGCGGCTGAATATTACGGCTGGGACGGCGGTTTCTACGTAATGATTGCCGGCG
GCGTATTAGCCGTACTCTTAATGTTTATCGTGATGATTGAAGAAGGTAAACATAAAGCGAAATTAGGTGATCACTACGGT
AAATAA

Upstream 100 bases:

>100_bases
TGAATAATTTTTATGGAGTATTACTCTTTTTTATATAGAATATACTCGATTGTTCGTAATCGAACTTTTTATCAATAAAT
ATAAAATTTGGAGTGTTTCT

Downstream 100 bases:

>100_bases
TCCTACCGTACATCGTTAAAACTTAAGAGAGGAAATACTATCCGGTATTTCCTCTCTTTTTAATTTTAATCAAATTTTCG
CTTGTTTTTCCAAAAATCAG

Product: glycerol-3-phosphate transporter

Products: Proton [Cytoplasm]; glycerol-3-phosphate [Cytoplasm] [C]

Alternate protein names: G-3-P transporter; G-3-P permease [H]

Number of amino acids: Translated: 481; Mature: 481

Protein sequence:

>481_residues
MFGPFKPAPHIAELPADKIDARYKFLRWQVFAGIFFGYAAYYFVRANFDLAQKGLIEAGLYNKAELGIIGTGAGLAYGLS
KFVMAGMSDRSNPKVFLPFGLLLSGLCMTMMGLMPWATSGIAVMFIMIFLNGWFQGMGWPPCGRTMVHWWSKSERGTIVS
IWNCAHNVGGMVPGAMVLLASTIYFSNTGEHATAKDVWQQALYYPGIAAMIAAIPVYFVMKDTPQSCGLPPVEKWRNDYP
DDYNEETAEKDLSTKEIFVTYVLKNKLLWYIAIANVFVYLIRYGVLKWSPVYLGEVKHFNIKGTAWAYTIYELAAIPGTL
LCGWVSDKLFKGKRGLTGFIFMILTTIAVFALWKNPATPEAELAQYAGKAWYENPYQLMDFILMTTIGFLIYGPVMLIGL
HALELAPKKAAGTSAGFTGLFGYLGGTVSASAVVGWAAEYYGWDGGFYVMIAGGVLAVLLMFIVMIEEGKHKAKLGDHYG
K

Sequences:

>Translated_481_residues
MFGPFKPAPHIAELPADKIDARYKFLRWQVFAGIFFGYAAYYFVRANFDLAQKGLIEAGLYNKAELGIIGTGAGLAYGLS
KFVMAGMSDRSNPKVFLPFGLLLSGLCMTMMGLMPWATSGIAVMFIMIFLNGWFQGMGWPPCGRTMVHWWSKSERGTIVS
IWNCAHNVGGMVPGAMVLLASTIYFSNTGEHATAKDVWQQALYYPGIAAMIAAIPVYFVMKDTPQSCGLPPVEKWRNDYP
DDYNEETAEKDLSTKEIFVTYVLKNKLLWYIAIANVFVYLIRYGVLKWSPVYLGEVKHFNIKGTAWAYTIYELAAIPGTL
LCGWVSDKLFKGKRGLTGFIFMILTTIAVFALWKNPATPEAELAQYAGKAWYENPYQLMDFILMTTIGFLIYGPVMLIGL
HALELAPKKAAGTSAGFTGLFGYLGGTVSASAVVGWAAEYYGWDGGFYVMIAGGVLAVLLMFIVMIEEGKHKAKLGDHYG
K
>Mature_481_residues
MFGPFKPAPHIAELPADKIDARYKFLRWQVFAGIFFGYAAYYFVRANFDLAQKGLIEAGLYNKAELGIIGTGAGLAYGLS
KFVMAGMSDRSNPKVFLPFGLLLSGLCMTMMGLMPWATSGIAVMFIMIFLNGWFQGMGWPPCGRTMVHWWSKSERGTIVS
IWNCAHNVGGMVPGAMVLLASTIYFSNTGEHATAKDVWQQALYYPGIAAMIAAIPVYFVMKDTPQSCGLPPVEKWRNDYP
DDYNEETAEKDLSTKEIFVTYVLKNKLLWYIAIANVFVYLIRYGVLKWSPVYLGEVKHFNIKGTAWAYTIYELAAIPGTL
LCGWVSDKLFKGKRGLTGFIFMILTTIAVFALWKNPATPEAELAQYAGKAWYENPYQLMDFILMTTIGFLIYGPVMLIGL
HALELAPKKAAGTSAGFTGLFGYLGGTVSASAVVGWAAEYYGWDGGFYVMIAGGVLAVLLMFIVMIEEGKHKAKLGDHYG
K

Specific function: Responsible for glycerol-3-phosphate uptake [H]

COG id: COG2271

COG function: function code G; Sugar phosphate permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family [H]

Homologues:

Organism=Homo sapiens, GI256219543, Length=480, Percent_Identity=25, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI256219598, Length=465, Percent_Identity=24.9462365591398, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI4503847, Length=465, Percent_Identity=24.9462365591398, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI256219483, Length=465, Percent_Identity=24.9462365591398, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI223717983, Length=433, Percent_Identity=23.094688221709, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI38093649, Length=433, Percent_Identity=23.094688221709, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI256219564, Length=388, Percent_Identity=23.1958762886598, Blast_Score=87, Evalue=3e-17,
Organism=Escherichia coli, GI1788573, Length=481, Percent_Identity=59.6673596673597, Blast_Score=580, Evalue=1e-166,
Organism=Escherichia coli, GI87082310, Length=466, Percent_Identity=33.9055793991416, Blast_Score=254, Evalue=1e-68,
Organism=Escherichia coli, GI2367259, Length=452, Percent_Identity=31.6371681415929, Blast_Score=207, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI133930953, Length=483, Percent_Identity=21.3250517598344, Blast_Score=79, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17542316, Length=474, Percent_Identity=21.7299578059072, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17564204, Length=427, Percent_Identity=25.0585480093677, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17564202, Length=416, Percent_Identity=25, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI133901856, Length=470, Percent_Identity=23.1914893617021, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI133901854, Length=470, Percent_Identity=23.1914893617021, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005267
- InterPro:   IPR000849
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR021159 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 53203; Mature: 53203

Theoretical pI: Translated: 8.72; Mature: 8.72

Prosite motif: PS50850 MFS ; PS00942 GLPT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGPFKPAPHIAELPADKIDARYKFLRWQVFAGIFFGYAAYYFVRANFDLAQKGLIEAGL
CCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCC
YNKAELGIIGTGAGLAYGLSKFVMAGMSDRSNPKVFLPFGLLLSGLCMTMMGLMPWATSG
CCCCCCCEEECCCHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCHH
IAVMFIMIFLNGWFQGMGWPPCGRTMVHWWSKSERGTIVSIWNCAHNVGGMVPGAMVLLA
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCEEEEEHHHHHCCCCCHHHHHHHH
STIYFSNTGEHATAKDVWQQALYYPGIAAMIAAIPVYFVMKDTPQSCGLPPVEKWRNDYP
HHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHEEECCCCCCCCCCCHHHHCCCCC
DDYNEETAEKDLSTKEIFVTYVLKNKLLWYIAIANVFVYLIRYGVLKWSPVYLGEVKHFN
CCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCEEEEE
IKGTAWAYTIYELAAIPGTLLCGWVSDKLFKGKRGLTGFIFMILTTIAVFALWKNPATPE
CCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCH
AELAQYAGKAWYENPYQLMDFILMTTIGFLIYGPVMLIGLHALELAPKKAAGTSAGFTGL
HHHHHHHCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
FGYLGGTVSASAVVGWAAEYYGWDGGFYVMIAGGVLAVLLMFIVMIEEGKHKAKLGDHYG
HHHHCCCHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCHHHCCCCCC
K
C
>Mature Secondary Structure
MFGPFKPAPHIAELPADKIDARYKFLRWQVFAGIFFGYAAYYFVRANFDLAQKGLIEAGL
CCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCC
YNKAELGIIGTGAGLAYGLSKFVMAGMSDRSNPKVFLPFGLLLSGLCMTMMGLMPWATSG
CCCCCCCEEECCCHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCHH
IAVMFIMIFLNGWFQGMGWPPCGRTMVHWWSKSERGTIVSIWNCAHNVGGMVPGAMVLLA
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCEEEEEHHHHHCCCCCHHHHHHHH
STIYFSNTGEHATAKDVWQQALYYPGIAAMIAAIPVYFVMKDTPQSCGLPPVEKWRNDYP
HHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHEEECCCCCCCCCCCHHHHCCCCC
DDYNEETAEKDLSTKEIFVTYVLKNKLLWYIAIANVFVYLIRYGVLKWSPVYLGEVKHFN
CCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCEEEEE
IKGTAWAYTIYELAAIPGTLLCGWVSDKLFKGKRGLTGFIFMILTTIAVFALWKNPATPE
CCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCH
AELAQYAGKAWYENPYQLMDFILMTTIGFLIYGPVMLIGLHALELAPKKAAGTSAGFTGL
HHHHHHHCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
FGYLGGTVSASAVVGWAAEYYGWDGGFYVMIAGGVLAVLLMFIVMIEEGKHKAKLGDHYG
HHHHCCCHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCHHHCCCCCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; glycerol-3-phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + glycerol-3-phosphate [Periplasm] = Proton [Cytoplasm] + glycerol-3-phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800; 9714837 [H]