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The map label for this gene is dsbB

Identifier: 126207805

GI number: 126207805

Start: 358114

End: 358653

Strand: Reverse

Name: dsbB

Synonym: APL_0321

Alternate gene names: 126207805

Gene position: 358653-358114 (Counterclockwise)

Preceding gene: 126207806

Following gene: 126207804

Centisome position: 15.77

GC content: 42.59

Gene sequence:

>540_bases
ATGCTCAGTTACTTTAAAGAACTCTCATTAAATCGAACCGCATGGCTACTGCTTGCTTTTGTTGCTTTCGCACTTGAAGC
AAGTGCCATTTATTTTCAATACGGAATGGGATTAGTGCCTTGCGTAATGTGCGTTTATGAACGTTTGGCAATTTTCGGAT
TACTTATCGCTGGGTTAGTCGGTGCCATTTCACCTCGTTTTTTCCTAACACGCTGGTTAGCATTATTACTTTGGGGATTT
AGTGCCTTCAAAGGACTTGCTCTTGCAATCAAACATCATGATTACCAAGCGAATCCTTCCCCTTGGAACCAATGCGAGTT
TAAACCCGAATTCCCGCAAACGATGCCGTTTGATCAGTGGTTCCCAAGTATCTTTGCCCCGGGTCCGGTCAATTGCAGCG
AAAAACAATGGGAAATGTTCGGACTTGGTATGCCGGAATGGCTTATCCTCGCATTTTCTATTTTTGCTCTTATGTTCGTT
ATCGTATTGCTTAGTCAATTTAAACGAGCAAAACCTCAGTACCGTAGCGTATTCAGATAA

Upstream 100 bases:

>100_bases
ATAATTCAAAGAATCTCCCCTAAAAGTGGGGAGATTTTTTTACGAAAACCGAACAAAATCAGGTACAATGTAAAAATTAT
TCAGACCAGAGGTGCCTATT

Downstream 100 bases:

>100_bases
TCTTACAAGCGGTCGAATTTTTGCAAAATTTTGCTGAAATCCGACCGCTTTTTTATAACTATAATAAGGAAATACAATGT
CAAACTTATCTCAATTAGAA

Product: disulfide bond formation protein B

Products: NA

Alternate protein names: Disulfide oxidoreductase

Number of amino acids: Translated: 179; Mature: 179

Protein sequence:

>179_residues
MLSYFKELSLNRTAWLLLAFVAFALEASAIYFQYGMGLVPCVMCVYERLAIFGLLIAGLVGAISPRFFLTRWLALLLWGF
SAFKGLALAIKHHDYQANPSPWNQCEFKPEFPQTMPFDQWFPSIFAPGPVNCSEKQWEMFGLGMPEWLILAFSIFALMFV
IVLLSQFKRAKPQYRSVFR

Sequences:

>Translated_179_residues
MLSYFKELSLNRTAWLLLAFVAFALEASAIYFQYGMGLVPCVMCVYERLAIFGLLIAGLVGAISPRFFLTRWLALLLWGF
SAFKGLALAIKHHDYQANPSPWNQCEFKPEFPQTMPFDQWFPSIFAPGPVNCSEKQWEMFGLGMPEWLILAFSIFALMFV
IVLLSQFKRAKPQYRSVFR
>Mature_179_residues
MLSYFKELSLNRTAWLLLAFVAFALEASAIYFQYGMGLVPCVMCVYERLAIFGLLIAGLVGAISPRFFLTRWLALLLWGF
SAFKGLALAIKHHDYQANPSPWNQCEFKPEFPQTMPFDQWFPSIFAPGPVNCSEKQWEMFGLGMPEWLILAFSIFALMFV
IVLLSQFKRAKPQYRSVFR

Specific function: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein

COG id: COG1495

COG function: function code O; Disulfide bond formation protein DsbB

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DsbB family

Homologues:

Organism=Escherichia coli, GI1787433, Length=173, Percent_Identity=43.9306358381503, Blast_Score=155, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DSBB_ACTP2 (A3MZ39)

Other databases:

- EMBL:   CP000569
- RefSeq:   YP_001053030.1
- ProteinModelPortal:   A3MZ39
- SMR:   A3MZ39
- STRING:   A3MZ39
- GeneID:   4849109
- GenomeReviews:   CP000569_GR
- KEGG:   apl:APL_0321
- eggNOG:   COG1495
- HOGENOM:   HBG637909
- OMA:   ALYFQHV
- PhylomeDB:   A3MZ39
- ProtClustDB:   PRK01749
- BioCyc:   APLE416269:APL_0321-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_00286
- InterPro:   IPR003752
- InterPro:   IPR022920

Pfam domain/function: PF02600 DsbB

EC number: NA

Molecular weight: Translated: 20601; Mature: 20601

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1bea7af8)-; HASH(0x1bed88dc)-; HASH(0x1b3d403c)-; HASH(0x1bf697a8)-;

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSYFKELSLNRTAWLLLAFVAFALEASAIYFQYGMGLVPCVMCVYERLAIFGLLIAGLV
CCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
GAISPRFFLTRWLALLLWGFSAFKGLALAIKHHDYQANPSPWNQCEFKPEFPQTMPFDQW
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHH
FPSIFAPGPVNCSEKQWEMFGLGMPEWLILAFSIFALMFVIVLLSQFKRAKPQYRSVFR
HHHHCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCH
>Mature Secondary Structure
MLSYFKELSLNRTAWLLLAFVAFALEASAIYFQYGMGLVPCVMCVYERLAIFGLLIAGLV
CCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
GAISPRFFLTRWLALLLWGFSAFKGLALAIKHHDYQANPSPWNQCEFKPEFPQTMPFDQW
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHH
FPSIFAPGPVNCSEKQWEMFGLGMPEWLILAFSIFALMFVIVLLSQFKRAKPQYRSVFR
HHHHCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA