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The map label for this gene is recD [H]

Identifier: 126207741

GI number: 126207741

Start: 276157

End: 278094

Strand: Direct

Name: recD [H]

Synonym: APL_0253

Alternate gene names: 126207741

Gene position: 276157-278094 (Clockwise)

Preceding gene: 126207739

Following gene: 126207743

Centisome position: 12.14

GC content: 38.6

Gene sequence:

>1938_bases
ATGCTGACGCTTTTATATGAGTTAAAAGAAACGAATGTGATTTCCGAATTGGATTATCAATTCGCTAAAATGATTGATCG
TAAACAGCAAAGTTATCCCTATACCGAACAACAAAAAAACTTGGCGGTATTGCTTGCCGCATTAGTTTCTTTTCACGTAA
TGCAAGGTCATGCCGCTATTCGTTTGGATTCTCAAGCCTCACGGTTTTTTTTCGGTTTATCAAATCGAAATGAGGAAAAG
GCGCTTAATGATGAAATTTTGCAAAAAATCGGCGGAATCACGCCGCTTGAATGGCAGGGCGTATTACAAAATCATATTGC
GTTTAGTTCGGATCCTAAGCAAGTCGCACCGATGTTGTTTCAACACGGGTTACTTTATTTTTATCGTTATTGGCAGGCGG
AAAACAATATTGCGAATTACTTAGTGAAAGCGGTCGAATTTCCCGAACAAATTGCCAATACCGCATTGGATAAGCAAATT
CTAGAAAAACTATTTGAAAAGTCGGATGAAGTAAATTGGCAAAAAATAGCGGTCGCTACGGCTATCAAACAAAAGTTTAG
CATAATTTCAGGCGGGCCGGGAACCGGTAAAACTACAACGGTCGCCAAATTATTAGCTGCGTTGCAAGAAAAACAGCTAC
GTAGCGGTAAAGCAATGTTGAATGTTGCGCTTGTCGCACCGACAGGAAAAGCGGCGGCACGTTTAAAAGAGTCAATCACA
TTAAGTTTAAGCGTGCTTAATTTGAATTTTGAAATTCCAACGACCGCCTCGACAATTCATCGTTTGTTAGGAATACGTCC
GCAAAGTGATGAGCCTCGTTATCACTCAAAAAATCCGTTACATATTGATCTTTTAGTGGTGGATGAAGCGTCTATGATTG
ATCTTTTCTTAATGGAAAAATTAATGGCGGCATTAAAACCGAATACCCGATTAATTATTTTAGGCGATAAAGATCAGCTT
GCGTCGGTTGAAGCCGGAGCGATTATGGGAGAACTCGGAGCGTTTCTTCAACAGGGATATAGCCGGAAACATTGCGATTA
TTTGAATCAAGTTACCGAGTATCAATTAGTTCCGAAAGGAAAATCATTACCTATTTGTGATTCGTTATGTCATTTGAAAA
AAAGTTATCGTTTTGACGCTAATTCCGGAATCGGTCAGTTGGCGAAACTGGTTAATGAAAAGCAAGCGGTTGAATCTTGG
CAACTTTTTGCAAAAGGCTCAGCGGATTTATCTTTGATCGAATATGCACACACTTCGGATTTCCCGGAAAAACAGCAGTG
GATTCAAAATTGCGTGAAACAAATAACAGATAAAGCGGTCGAGCTTTATAAGGAATATCTAACGCTTGTTAAACAACGTT
ACAATAATCCGACGAAAGTGTCGGTAAATGAAATTTTCGAGGTTTTTCAAAAAGTAAGATTCTTATCCGCATTGCGTATA
AGTGAATTGGGCGTAGAGCAATTAAATAAAAGGATAGAAACGGCATTAGCGGCGGCAAAACTGATTTCTTTAGAACAAAG
TAAAAATTACTATATCGGTAAACCGTTACTCATTACACAGAACTCGCCGCAAAATCATATTTATAGCGGCGATATAGGGA
TTATCTTACCGGATGAGAACGGAATATCGAGAGTTTATTTTGATACGAAAATTGACGATGGATATTTAAGTCTTTCTCTG
AATAGACTTCCCGAATTTGAACCGGCTTATGTAATGACAGTTCATAAGTCGCAAGGTTCTGAATTCGAACATACCTTACT
GATAACGCCATTGCACTTTGCACCGGTTATGAGTAAAGAATTAATTTATACGGCGATTACCCGAGCTAAAAAGCATTTTA
CTTTATTCGGAGAAAAACAAGTTTGGTTACAGGCGGTGAATAATAATCTTCAGCGTCAAAGCGGATTAAAAGCACAATTA
ATGCACTTGTTCAGTTAA

Upstream 100 bases:

>100_bases
TTTGAAAGTAAAGATAATTATACGCTCGATGAGAATAAATGGACAACGAATAATGAACATCGGATAATTCTAAGCAGATT
AAGTTTAGAGGATTTTATTT

Downstream 100 bases:

>100_bases
AATAATATGCGAATTGTATTAAATCTGTTCTTTCAATCACTTTTTCAAGATTTTTTTGCAAAAAGAACTTGCAAGGAATT
TAGATTTCTCTATAATGCAT

Product: exodeoxyribonuclease V alpha chain

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 645; Mature: 645

Protein sequence:

>645_residues
MLTLLYELKETNVISELDYQFAKMIDRKQQSYPYTEQQKNLAVLLAALVSFHVMQGHAAIRLDSQASRFFFGLSNRNEEK
ALNDEILQKIGGITPLEWQGVLQNHIAFSSDPKQVAPMLFQHGLLYFYRYWQAENNIANYLVKAVEFPEQIANTALDKQI
LEKLFEKSDEVNWQKIAVATAIKQKFSIISGGPGTGKTTTVAKLLAALQEKQLRSGKAMLNVALVAPTGKAAARLKESIT
LSLSVLNLNFEIPTTASTIHRLLGIRPQSDEPRYHSKNPLHIDLLVVDEASMIDLFLMEKLMAALKPNTRLIILGDKDQL
ASVEAGAIMGELGAFLQQGYSRKHCDYLNQVTEYQLVPKGKSLPICDSLCHLKKSYRFDANSGIGQLAKLVNEKQAVESW
QLFAKGSADLSLIEYAHTSDFPEKQQWIQNCVKQITDKAVELYKEYLTLVKQRYNNPTKVSVNEIFEVFQKVRFLSALRI
SELGVEQLNKRIETALAAAKLISLEQSKNYYIGKPLLITQNSPQNHIYSGDIGIILPDENGISRVYFDTKIDDGYLSLSL
NRLPEFEPAYVMTVHKSQGSEFEHTLLITPLHFAPVMSKELIYTAITRAKKHFTLFGEKQVWLQAVNNNLQRQSGLKAQL
MHLFS

Sequences:

>Translated_645_residues
MLTLLYELKETNVISELDYQFAKMIDRKQQSYPYTEQQKNLAVLLAALVSFHVMQGHAAIRLDSQASRFFFGLSNRNEEK
ALNDEILQKIGGITPLEWQGVLQNHIAFSSDPKQVAPMLFQHGLLYFYRYWQAENNIANYLVKAVEFPEQIANTALDKQI
LEKLFEKSDEVNWQKIAVATAIKQKFSIISGGPGTGKTTTVAKLLAALQEKQLRSGKAMLNVALVAPTGKAAARLKESIT
LSLSVLNLNFEIPTTASTIHRLLGIRPQSDEPRYHSKNPLHIDLLVVDEASMIDLFLMEKLMAALKPNTRLIILGDKDQL
ASVEAGAIMGELGAFLQQGYSRKHCDYLNQVTEYQLVPKGKSLPICDSLCHLKKSYRFDANSGIGQLAKLVNEKQAVESW
QLFAKGSADLSLIEYAHTSDFPEKQQWIQNCVKQITDKAVELYKEYLTLVKQRYNNPTKVSVNEIFEVFQKVRFLSALRI
SELGVEQLNKRIETALAAAKLISLEQSKNYYIGKPLLITQNSPQNHIYSGDIGIILPDENGISRVYFDTKIDDGYLSLSL
NRLPEFEPAYVMTVHKSQGSEFEHTLLITPLHFAPVMSKELIYTAITRAKKHFTLFGEKQVWLQAVNNNLQRQSGLKAQL
MHLFS
>Mature_645_residues
MLTLLYELKETNVISELDYQFAKMIDRKQQSYPYTEQQKNLAVLLAALVSFHVMQGHAAIRLDSQASRFFFGLSNRNEEK
ALNDEILQKIGGITPLEWQGVLQNHIAFSSDPKQVAPMLFQHGLLYFYRYWQAENNIANYLVKAVEFPEQIANTALDKQI
LEKLFEKSDEVNWQKIAVATAIKQKFSIISGGPGTGKTTTVAKLLAALQEKQLRSGKAMLNVALVAPTGKAAARLKESIT
LSLSVLNLNFEIPTTASTIHRLLGIRPQSDEPRYHSKNPLHIDLLVVDEASMIDLFLMEKLMAALKPNTRLIILGDKDQL
ASVEAGAIMGELGAFLQQGYSRKHCDYLNQVTEYQLVPKGKSLPICDSLCHLKKSYRFDANSGIGQLAKLVNEKQAVESW
QLFAKGSADLSLIEYAHTSDFPEKQQWIQNCVKQITDKAVELYKEYLTLVKQRYNNPTKVSVNEIFEVFQKVRFLSALRI
SELGVEQLNKRIETALAAAKLISLEQSKNYYIGKPLLITQNSPQNHIYSGDIGIILPDENGISRVYFDTKIDDGYLSLSL
NRLPEFEPAYVMTVHKSQGSEFEHTLLITPLHFAPVMSKELIYTAITRAKKHFTLFGEKQVWLQAVNNNLQRQSGLKAQL
MHLFS

Specific function: Exhibits several catalytic activities, including ATP- dependent exonuclease, ATP-stimulated endonuclease, ATP-dependent unwinding and DNA-dependent ATPase activities. Strand cleavage occurs 5' to 3' during the unwinding of duplex DNA at CHI sequences, whi

COG id: COG0507

COG function: function code L; ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recD family [H]

Homologues:

Organism=Escherichia coli, GI1789182, Length=655, Percent_Identity=38.9312977099237, Blast_Score=357, Evalue=1e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007807
- InterPro:   IPR006344
- InterPro:   IPR000606 [H]

Pfam domain/function: PF05127 DUF699; PF01443 Viral_helicase1 [H]

EC number: =3.1.11.5 [H]

Molecular weight: Translated: 72845; Mature: 72845

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTLLYELKETNVISELDYQFAKMIDRKQQSYPYTEQQKNLAVLLAALVSFHVMQGHAAI
CEEEEEEHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEEE
RLDSQASRFFFGLSNRNEEKALNDEILQKIGGITPLEWQGVLQNHIAFSSDPKQVAPMLF
EECCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHHHHHHHH
QHGLLYFYRYWQAENNIANYLVKAVEFPEQIANTALDKQILEKLFEKSDEVNWQKIAVAT
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
AIKQKFSIISGGPGTGKTTTVAKLLAALQEKQLRSGKAMLNVALVAPTGKAAARLKESIT
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHE
LSLSVLNLNFEIPTTASTIHRLLGIRPQSDEPRYHSKNPLHIDLLVVDEASMIDLFLMEK
EEEEEEEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHH
LMAALKPNTRLIILGDKDQLASVEAGAIMGELGAFLQQGYSRKHCDYLNQVTEYQLVPKG
HHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHEEECCCC
KSLPICDSLCHLKKSYRFDANSGIGQLAKLVNEKQAVESWQLFAKGSADLSLIEYAHTSD
CCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEHEEECCCCC
FPEKQQWIQNCVKQITDKAVELYKEYLTLVKQRYNNPTKVSVNEIFEVFQKVRFLSALRI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHH
SELGVEQLNKRIETALAAAKLISLEQSKNYYIGKPLLITQNSPQNHIYSGDIGIILPDEN
HHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEECCCCCCCEEECCEEEEEECCC
GISRVYFDTKIDDGYLSLSLNRLPEFEPAYVMTVHKSQGSEFEHTLLITPLHFAPVMSKE
CCEEEEEECCCCCCEEEEEECCCCCCCCCEEEEEECCCCCCCCEEEEEECHHHHHHHHHH
LIYTAITRAKKHFTLFGEKQVWLQAVNNNLQRQSGLKAQLMHLFS
HHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHCC
>Mature Secondary Structure
MLTLLYELKETNVISELDYQFAKMIDRKQQSYPYTEQQKNLAVLLAALVSFHVMQGHAAI
CEEEEEEHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEEE
RLDSQASRFFFGLSNRNEEKALNDEILQKIGGITPLEWQGVLQNHIAFSSDPKQVAPMLF
EECCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHHHHHHHH
QHGLLYFYRYWQAENNIANYLVKAVEFPEQIANTALDKQILEKLFEKSDEVNWQKIAVAT
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
AIKQKFSIISGGPGTGKTTTVAKLLAALQEKQLRSGKAMLNVALVAPTGKAAARLKESIT
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHE
LSLSVLNLNFEIPTTASTIHRLLGIRPQSDEPRYHSKNPLHIDLLVVDEASMIDLFLMEK
EEEEEEEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHH
LMAALKPNTRLIILGDKDQLASVEAGAIMGELGAFLQQGYSRKHCDYLNQVTEYQLVPKG
HHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHEEECCCC
KSLPICDSLCHLKKSYRFDANSGIGQLAKLVNEKQAVESWQLFAKGSADLSLIEYAHTSD
CCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEHEEECCCCC
FPEKQQWIQNCVKQITDKAVELYKEYLTLVKQRYNNPTKVSVNEIFEVFQKVRFLSALRI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHH
SELGVEQLNKRIETALAAAKLISLEQSKNYYIGKPLLITQNSPQNHIYSGDIGIILPDEN
HHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEECCCCCCCEEECCEEEEEECCC
GISRVYFDTKIDDGYLSLSLNRLPEFEPAYVMTVHKSQGSEFEHTLLITPLHFAPVMSKE
CCEEEEEECCCCCCEEEEEECCCCCCCCCEEEEEECCCCCCCCEEEEEECHHHHHHHHHH
LIYTAITRAKKHFTLFGEKQVWLQAVNNNLQRQSGLKAQLMHLFS
HHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]