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The map label for this gene is hofQ [H]

Identifier: 126207688

GI number: 126207688

Start: 219442

End: 220740

Strand: Direct

Name: hofQ [H]

Synonym: APL_0200

Alternate gene names: 126207688

Gene position: 219442-220740 (Clockwise)

Preceding gene: 126207687

Following gene: 126207689

Centisome position: 9.65

GC content: 38.26

Gene sequence:

>1299_bases
ATGCGAAAAATGATTTGGTTGCTCCTGTTTATATTAACGCCGGTTATGGCAAATACTTTTTCTCTCTCGCTGAAAAATGC
GCCGACTGCGGAAATTTTAAGTTATTTAGCCGAAGAATACGGTAAAAATATCGTGTTAAGCGACAATATTGAGACAAATA
CTACATTAAGAATTGAAAATAGTGATTTTGACAGCGTATTAAAAAGTATTACTCGGGCGAATAAACTCACGAGTGCATAC
GAAAAACAGATCTATTTTATCGGGCATAAAAAAGATGAGAAAGCGGCTACGGCAATAGGCGTAAATTCTGATTTATTGAA
ACCTAAATTGATCACTAAGACAATAAAATTAGATTATGCGAAGGCGGCGGAAGTGATTGAATCTTTAACTAAAGGAAGCG
GCCATTTTTTATCGGAAAACGGCTATTTGCATTTTGATGATCGTAGTAACAGTTTGATTATTAAAGACAGTCCGGAATCG
ATGAAAAATATCGTGCAATTAATCAGAAACTTAGATAAACCGACCGAACAGATTGCAATTGAAGCCAGAATTGTCACGAT
AAGCAGTGAGAATTTACAAGAATTAGGTGTGCGTTGGGGGATATTTGCTCCTACAAACGGACACCATAAAATTGCCGGTT
CGCTTGAAGCGAACGGATTACCGAATACTAATCGTTTAAACGTAAATTTTCCGGTAAATAATGCCGCTTCTATTGCACTA
CAAGTGGCGAAAATTAATGGGCGAGTGCTTGATTTGGAACTTACCGCTTTGGAACAAGAAAATAATGTTGAGATTATCGC
CAGCCCTCGTTTATTAACCACCAATAAGAAGCCGGCAAGCATTAAGCAAGGAACGGAAGTTCCTTATGTGCTGTATAACC
GTAAAGACGAAGTGAAAAATATCGAATTTAAAGAAGCGGTTTTAGGTTTACAAGTGACGCCGCATATTTCAAACGATAAG
CAAATTTTGCTCGATTTGGTAGTCACCCAAAACTCACCTAATTCGACCGGTTCAACCCTACAAGGCTTAGTGACGATTGA
TAAGCAGGAACTGAATACGCAAGTATTTGCTCAGCATGGCGAAACGATTGTGCTAGGCGGTATTTTTCAGCATTTAACCG
CAAAAGGTGAGGACAGAGTGCCGATTTTAGGTTCGATTCCGGTACTTAAAAAGTTATTTAGCCATTCTAGTGATAAAATT
AGTAAGCGTGAACTAGTGATTTTTGTGACGCCTTACATTGTTAAAAACGGACAACCGCAAATTTCCTCACATTCTTCACA
GAAATTAGCGCCAAAATAG

Upstream 100 bases:

>100_bases
TAGACATTGATTTAAAATCTATTCGTTATATTAATTGGCAAACAGAGAAAAATTGTGAGTCTCCGACCCCGGTTATCTTA
AAATTATAGGTGGAACAAGA

Downstream 100 bases:

>100_bases
AATAACTTGTGCTAAAATCTCTCCTTTAAATTGCAATAAGTTATTTAGTAATTGCATACGAATTTTTATGTGGCGGTTGA
TTAAAATACCGCCATTTTGC

Product: type II secretory pathway, component HofQ

Products: NA

Alternate protein names: DNA transformation protein ComE [H]

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MRKMIWLLLFILTPVMANTFSLSLKNAPTAEILSYLAEEYGKNIVLSDNIETNTTLRIENSDFDSVLKSITRANKLTSAY
EKQIYFIGHKKDEKAATAIGVNSDLLKPKLITKTIKLDYAKAAEVIESLTKGSGHFLSENGYLHFDDRSNSLIIKDSPES
MKNIVQLIRNLDKPTEQIAIEARIVTISSENLQELGVRWGIFAPTNGHHKIAGSLEANGLPNTNRLNVNFPVNNAASIAL
QVAKINGRVLDLELTALEQENNVEIIASPRLLTTNKKPASIKQGTEVPYVLYNRKDEVKNIEFKEAVLGLQVTPHISNDK
QILLDLVVTQNSPNSTGSTLQGLVTIDKQELNTQVFAQHGETIVLGGIFQHLTAKGEDRVPILGSIPVLKKLFSHSSDKI
SKRELVIFVTPYIVKNGQPQISSHSSQKLAPK

Sequences:

>Translated_432_residues
MRKMIWLLLFILTPVMANTFSLSLKNAPTAEILSYLAEEYGKNIVLSDNIETNTTLRIENSDFDSVLKSITRANKLTSAY
EKQIYFIGHKKDEKAATAIGVNSDLLKPKLITKTIKLDYAKAAEVIESLTKGSGHFLSENGYLHFDDRSNSLIIKDSPES
MKNIVQLIRNLDKPTEQIAIEARIVTISSENLQELGVRWGIFAPTNGHHKIAGSLEANGLPNTNRLNVNFPVNNAASIAL
QVAKINGRVLDLELTALEQENNVEIIASPRLLTTNKKPASIKQGTEVPYVLYNRKDEVKNIEFKEAVLGLQVTPHISNDK
QILLDLVVTQNSPNSTGSTLQGLVTIDKQELNTQVFAQHGETIVLGGIFQHLTAKGEDRVPILGSIPVLKKLFSHSSDKI
SKRELVIFVTPYIVKNGQPQISSHSSQKLAPK
>Mature_432_residues
MRKMIWLLLFILTPVMANTFSLSLKNAPTAEILSYLAEEYGKNIVLSDNIETNTTLRIENSDFDSVLKSITRANKLTSAY
EKQIYFIGHKKDEKAATAIGVNSDLLKPKLITKTIKLDYAKAAEVIESLTKGSGHFLSENGYLHFDDRSNSLIIKDSPES
MKNIVQLIRNLDKPTEQIAIEARIVTISSENLQELGVRWGIFAPTNGHHKIAGSLEANGLPNTNRLNVNFPVNNAASIAL
QVAKINGRVLDLELTALEQENNVEIIASPRLLTTNKKPASIKQGTEVPYVLYNRKDEVKNIEFKEAVLGLQVTPHISNDK
QILLDLVVTQNSPNSTGSTLQGLVTIDKQELNTQVFAQHGETIVLGGIFQHLTAKGEDRVPILGSIPVLKKLFSHSSDKI
SKRELVIFVTPYIVKNGQPQISSHSSQKLAPK

Specific function: Involved in transformation (competence for DNA uptake) [H]

COG id: COG4796

COG function: function code U; Type II secretory pathway, component HofQ

Gene ontology:

Cell location: Cell outer membrane (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP D family [H]

Homologues:

Organism=Escherichia coli, GI1789793, Length=432, Percent_Identity=34.2592592592593, Blast_Score=249, Evalue=3e-67,
Organism=Escherichia coli, GI87082242, Length=335, Percent_Identity=28.0597014925373, Blast_Score=106, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001775
- InterPro:   IPR005644
- InterPro:   IPR013355
- InterPro:   IPR004846
- InterPro:   IPR004845
- InterPro:   IPR001814 [H]

Pfam domain/function: PF00263 Secretin; PF03958 Secretin_N [H]

EC number: NA

Molecular weight: Translated: 47777; Mature: 47777

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: PS00875 T2SP_D

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKMIWLLLFILTPVMANTFSLSLKNAPTAEILSYLAEEYGKNIVLSDNIETNTTLRIEN
CHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHCCEEEEECCCCCCEEEEEEC
SDFDSVLKSITRANKLTSAYEKQIYFIGHKKDEKAATAIGVNSDLLKPKLITKTIKLDYA
CCHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCHHEEECCCCHHCCCHHHHHHHEECHH
KAAEVIESLTKGSGHFLSENGYLHFDDRSNSLIIKDSPESMKNIVQLIRNLDKPTEQIAI
HHHHHHHHHHCCCCCEEECCCEEEECCCCCEEEEECCHHHHHHHHHHHHHCCCCCHHEEE
EARIVTISSENLQELGVRWGIFAPTNGHHKIAGSLEANGLPNTNRLNVNFPVNNAASIAL
EEEEEEECCCCHHHCCCEEEEECCCCCCEEEEECEECCCCCCCCEEEEEECCCCCCEEEE
QVAKINGRVLDLELTALEQENNVEIIASPRLLTTNKKPASIKQGTEVPYVLYNRKDEVKN
EEEEECCEEEEEEEEEECCCCCEEEEECCEEEECCCCCCCCCCCCCCCEEEECCCCCCCC
IEFKEAVLGLQVTPHISNDKQILLDLVVTQNSPNSTGSTLQGLVTIDKQELNTQVFAQHG
CCHHHHHCCEEECCCCCCCCEEEEEEEEECCCCCCCCCCEEEEEEECHHHHCHHHHHHCC
ETIVLGGIFQHLTAKGEDRVPILGSIPVLKKLFSHSSDKISKRELVIFVTPYIVKNGQPQ
CEEEEEHHHHHHHCCCCCCCCEEECCHHHHHHHCCCCCCCCCCEEEEEEECEEEECCCCC
ISSHSSQKLAPK
CCCCCCCCCCCC
>Mature Secondary Structure
MRKMIWLLLFILTPVMANTFSLSLKNAPTAEILSYLAEEYGKNIVLSDNIETNTTLRIEN
CHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHCCEEEEECCCCCCEEEEEEC
SDFDSVLKSITRANKLTSAYEKQIYFIGHKKDEKAATAIGVNSDLLKPKLITKTIKLDYA
CCHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCHHEEECCCCHHCCCHHHHHHHEECHH
KAAEVIESLTKGSGHFLSENGYLHFDDRSNSLIIKDSPESMKNIVQLIRNLDKPTEQIAI
HHHHHHHHHHCCCCCEEECCCEEEECCCCCEEEEECCHHHHHHHHHHHHHCCCCCHHEEE
EARIVTISSENLQELGVRWGIFAPTNGHHKIAGSLEANGLPNTNRLNVNFPVNNAASIAL
EEEEEEECCCCHHHCCCEEEEECCCCCCEEEEECEECCCCCCCCEEEEEECCCCCCEEEE
QVAKINGRVLDLELTALEQENNVEIIASPRLLTTNKKPASIKQGTEVPYVLYNRKDEVKN
EEEEECCEEEEEEEEEECCCCCEEEEECCEEEECCCCCCCCCCCCCCCEEEECCCCCCCC
IEFKEAVLGLQVTPHISNDKQILLDLVVTQNSPNSTGSTLQGLVTIDKQELNTQVFAQHG
CCHHHHHCCEEECCCCCCCCEEEEEEEEECCCCCCCCCCEEEEEEECHHHHCHHHHHHCC
ETIVLGGIFQHLTAKGEDRVPILGSIPVLKKLFSHSSDKISKRELVIFVTPYIVKNGQPQ
CEEEEEHHHHHHHCCCCCCCCEEECCHHHHHHHCCCCCCCCCCEEEEEEECEEEECCCCC
ISSHSSQKLAPK
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1916268; 7542800; 1856167 [H]