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The map label for this gene is nqrE

Identifier: 126207642

GI number: 126207642

Start: 172073

End: 172669

Strand: Direct

Name: nqrE

Synonym: APL_0154

Alternate gene names: 126207642

Gene position: 172073-172669 (Clockwise)

Preceding gene: 126207641

Following gene: 126207643

Centisome position: 7.57

GC content: 40.03

Gene sequence:

>597_bases
ATGGAACATTATTTAAGTCTATTTGTTAAGTCCGTATTCATTGAGAATATGGCACTTTCTTTCTTCCTTGGTATGTGTAC
ATTCCTTGCGGTGTCTAAGAAAGTTTCAACTGCTTTTGGTTTAGGTATTGCGGTAATCGTCGTATTAGGTATTGCGGTAC
CGGCTAACCAATTAGTTTATACTCACGTATTAAAAGACGGCGCACTTGTTGAAGGTGTGGATTTAAGTTTCTTAAACTTC
ATCACGTTCATCGGTGTGATTGCGGCGCTTGTTCAAATCTTAGAAATGATTTTGGATAAGTTCTTTCCGGCATTATATAG
TGCATTAGGGATCTTCTTACCGTTGATTACCGTAAACTGTGCAATCTTCGGTGGCGTATCGTTTATGGTTCAACGTGAAT
ATAACTTCACGGAATCGGTGGTTTACGGTCTCGGTGCCGGTACGGGTTGGATGTTAGCAATCGTTGCGCTTGCAGGTTTA
ACGGAAAAAATGAAATATTCTGACGTTCCGGCTGGTTTACGTGGTTTAGGTATTACCTTTATCACTGTAGGTTTAATGGC
GTTAGGTTTCATGTCATTCTCGGGCATTCAATTATAA

Upstream 100 bases:

>100_bases
GCAAACGGCTTATTCTTATTGGCACCAAGTGCGTTCTTCATTATCGGTTTTGTGATTTGGGGAATCCGTACATGGAAACC
GGAGCAAGTGGAGAAATAAG

Downstream 100 bases:

>100_bases
GGAGCATATCGTGGATAGTAATTTTATTTTCGGTATTATCGCATTTACTGCTCTGGTATTAGTGCTTGCGGTGATCATTC
TTTTCGCTAAATCAAAATTA

Product: Na(+)-translocating NADH-quinone reductase subunit E

Products: NA

Alternate protein names: Na(+)-NQR subunit E; Na(+)-translocating NQR subunit E; NQR complex subunit E; NQR-1 subunit E

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MEHYLSLFVKSVFIENMALSFFLGMCTFLAVSKKVSTAFGLGIAVIVVLGIAVPANQLVYTHVLKDGALVEGVDLSFLNF
ITFIGVIAALVQILEMILDKFFPALYSALGIFLPLITVNCAIFGGVSFMVQREYNFTESVVYGLGAGTGWMLAIVALAGL
TEKMKYSDVPAGLRGLGITFITVGLMALGFMSFSGIQL

Sequences:

>Translated_198_residues
MEHYLSLFVKSVFIENMALSFFLGMCTFLAVSKKVSTAFGLGIAVIVVLGIAVPANQLVYTHVLKDGALVEGVDLSFLNF
ITFIGVIAALVQILEMILDKFFPALYSALGIFLPLITVNCAIFGGVSFMVQREYNFTESVVYGLGAGTGWMLAIVALAGL
TEKMKYSDVPAGLRGLGITFITVGLMALGFMSFSGIQL
>Mature_198_residues
MEHYLSLFVKSVFIENMALSFFLGMCTFLAVSKKVSTAFGLGIAVIVVLGIAVPANQLVYTHVLKDGALVEGVDLSFLNF
ITFIGVIAALVQILEMILDKFFPALYSALGIFLPLITVNCAIFGGVSFMVQREYNFTESVVYGLGAGTGWMLAIVALAGL
TEKMKYSDVPAGLRGLGITFITVGLMALGFMSFSGIQL

Specific function: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to nqrE are probably involved in the second step, the conversion of ubisemiqui

COG id: COG2209

COG function: function code C; Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrE

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nqrDE/rnfAE family

Homologues:

Organism=Escherichia coli, GI1787914, Length=196, Percent_Identity=43.3673469387755, Blast_Score=149, Evalue=1e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NQRE_ACTP2 (A3MYM6)

Other databases:

- EMBL:   CP000569
- RefSeq:   YP_001052867.1
- STRING:   A3MYM6
- GeneID:   4848756
- GenomeReviews:   CP000569_GR
- KEGG:   apl:APL_0154
- eggNOG:   COG2209
- HOGENOM:   HBG624915
- OMA:   FLGMCSF
- PhylomeDB:   A3MYM6
- ProtClustDB:   PRK02830
- BioCyc:   APLE416269:APL_0154-MONOMER
- HAMAP:   MF_00429
- InterPro:   IPR003667
- InterPro:   IPR010967
- PIRSF:   PIRSF006102
- TIGRFAMs:   TIGR01940

Pfam domain/function: PF02508 Rnf-Nqr

EC number: NA

Molecular weight: Translated: 21233; Mature: 21233

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1b1eb5e0)-; HASH(0x1afefddc)-; HASH(0x1a9b6f14)-; HASH(0x1b512394)-; HASH(0x1b50348c)-; HASH(0x1b9b1250)-;

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHYLSLFVKSVFIENMALSFFLGMCTFLAVSKKVSTAFGLGIAVIVVLGIAVPANQLVY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
THVLKDGALVEGVDLSFLNFITFIGVIAALVQILEMILDKFFPALYSALGIFLPLITVNC
HHHHHCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIFGGVSFMVQREYNFTESVVYGLGAGTGWMLAIVALAGLTEKMKYSDVPAGLRGLGITF
HHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
ITVGLMALGFMSFSGIQL
HHHHHHHHHHHHHCCCCH
>Mature Secondary Structure
MEHYLSLFVKSVFIENMALSFFLGMCTFLAVSKKVSTAFGLGIAVIVVLGIAVPANQLVY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
THVLKDGALVEGVDLSFLNFITFIGVIAALVQILEMILDKFFPALYSALGIFLPLITVNC
HHHHHCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIFGGVSFMVQREYNFTESVVYGLGAGTGWMLAIVALAGLTEKMKYSDVPAGLRGLGITF
HHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
ITVGLMALGFMSFSGIQL
HHHHHHHHHHHHHCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA