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The map label for this gene is dppC [H]

Identifier: 126207554

GI number: 126207554

Start: 79581

End: 80471

Strand: Direct

Name: dppC [H]

Synonym: APL_0066

Alternate gene names: 126207554

Gene position: 79581-80471 (Clockwise)

Preceding gene: 126207553

Following gene: 126207555

Centisome position: 3.5

GC content: 45.45

Gene sequence:

>891_bases
ATGTCTTCAACAACCCTTTCGGCACCGGCTCCGAAGACACCTTTACAAGAGTTTTGGTATTACTTTTGCCAAAACCGTGG
TGCGGTTATCGGGCTTGCCTTTATTACTCTTGTCTTTTTTGCTGCGGTATTTGCAGGTTGGGTCGCACCTTTTGACCCGA
TTGAGCAAAACCGTAGTGCCTTATTACTGCCTCTGGCGTGGATGGAGGGTGGTAATTCCACTTATTTGTTAGGAACCGAT
GATATTGGGCGTGATATTCTTTCTCGCATTATCTACGGTGCGCGTTTATCGGTATTTATCGGTTTGGTAATTGTGATTTT
ATCTTGCGTATTCGGCGTGATTTTAGGCTTACTTGCCGGCTATTACGGTGGTGTGATTGATATCGTGATTATGCGTTTTG
TCGATATTATGTTAGCCATTCCGAGTTTACTTCTCACCATTGGCGTGGTCACCATTTTAGGCCCGTCTTTGATTAACGCA
GCGATTGCGATTGCGATTGTTTCGATTCCAAGCTATGTACGTTTAACCCGTGCTTCGGTGATGAGCGAAAAAAATCGTGA
TTATGTGGTGGCGAGTCGAGTTGCCGGTGCCGGTGTATTACGTTTAATGTTTATTGTGATTTTACCGAACTGTCTGGCAC
CGTTAATCGTACAAATGACGATGGGTATTTCCAATGCGATTTTAGAACTTGCCGCACTTGGCTTCTTAGGAATAGGTGCG
CAGCCGCCGACACCGGAATTAGGTACAATGTTGGCGGAATCTCGTGGCTTTATGCAATCGGCGAACTGGTTGGTAACCAT
TCCGGGGCTTGCGATTTTATCGCTTGTATTAGCGTTTAACTTAATGGGTGACGGCTTACGTGATGCGCTCGATCCGAAAC
TGAAACAATAA

Upstream 100 bases:

>100_bases
ACCCAAGAATTCGACATCACTAAGCCTATTTTTCAGCTTTTACAAGCGGTTAAATTTACGCAACATTTTGCAAAATGATT
TGAATGGAGTGAGATACATA

Downstream 100 bases:

>100_bases
GGAGAGCAAGATGGCTTTATTAACGGTAGATCAGCTTTCTGTCCATTTCGGTGATGAGAAAGCGCCCTTCAAAGCGGTAG
ATCGTATTAGTTATACGATA

Product: dipeptide transport system permease protein DppC

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MSSTTLSAPAPKTPLQEFWYYFCQNRGAVIGLAFITLVFFAAVFAGWVAPFDPIEQNRSALLLPLAWMEGGNSTYLLGTD
DIGRDILSRIIYGARLSVFIGLVIVILSCVFGVILGLLAGYYGGVIDIVIMRFVDIMLAIPSLLLTIGVVTILGPSLINA
AIAIAIVSIPSYVRLTRASVMSEKNRDYVVASRVAGAGVLRLMFIVILPNCLAPLIVQMTMGISNAILELAALGFLGIGA
QPPTPELGTMLAESRGFMQSANWLVTIPGLAILSLVLAFNLMGDGLRDALDPKLKQ

Sequences:

>Translated_296_residues
MSSTTLSAPAPKTPLQEFWYYFCQNRGAVIGLAFITLVFFAAVFAGWVAPFDPIEQNRSALLLPLAWMEGGNSTYLLGTD
DIGRDILSRIIYGARLSVFIGLVIVILSCVFGVILGLLAGYYGGVIDIVIMRFVDIMLAIPSLLLTIGVVTILGPSLINA
AIAIAIVSIPSYVRLTRASVMSEKNRDYVVASRVAGAGVLRLMFIVILPNCLAPLIVQMTMGISNAILELAALGFLGIGA
QPPTPELGTMLAESRGFMQSANWLVTIPGLAILSLVLAFNLMGDGLRDALDPKLKQ
>Mature_295_residues
SSTTLSAPAPKTPLQEFWYYFCQNRGAVIGLAFITLVFFAAVFAGWVAPFDPIEQNRSALLLPLAWMEGGNSTYLLGTDD
IGRDILSRIIYGARLSVFIGLVIVILSCVFGVILGLLAGYYGGVIDIVIMRFVDIMLAIPSLLLTIGVVTILGPSLINAA
IAIAIVSIPSYVRLTRASVMSEKNRDYVVASRVAGAGVLRLMFIVILPNCLAPLIVQMTMGISNAILELAALGFLGIGAQ
PPTPELGTMLAESRGFMQSANWLVTIPGLAILSLVLAFNLMGDGLRDALDPKLKQ

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789964, Length=295, Percent_Identity=66.1016949152542, Blast_Score=361, Evalue=1e-101,
Organism=Escherichia coli, GI1787054, Length=284, Percent_Identity=42.2535211267606, Blast_Score=223, Evalue=1e-59,
Organism=Escherichia coli, GI1787760, Length=259, Percent_Identity=44.7876447876448, Blast_Score=213, Evalue=2e-56,
Organism=Escherichia coli, GI1787549, Length=288, Percent_Identity=38.5416666666667, Blast_Score=197, Evalue=7e-52,
Organism=Escherichia coli, GI1789889, Length=250, Percent_Identity=37.2, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1787498, Length=282, Percent_Identity=31.2056737588652, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1788505, Length=217, Percent_Identity=32.258064516129, Blast_Score=118, Evalue=5e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 31635; Mature: 31504

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSTTLSAPAPKTPLQEFWYYFCQNRGAVIGLAFITLVFFAAVFAGWVAPFDPIEQNRSA
CCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCE
LLLPLAWMEGGNSTYLLGTDDIGRDILSRIIYGARLSVFIGLVIVILSCVFGVILGLLAG
EEEEEHEECCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YYGGVIDIVIMRFVDIMLAIPSLLLTIGVVTILGPSLINAAIAIAIVSIPSYVRLTRASV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MSEKNRDYVVASRVAGAGVLRLMFIVILPNCLAPLIVQMTMGISNAILELAALGFLGIGA
HHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
QPPTPELGTMLAESRGFMQSANWLVTIPGLAILSLVLAFNLMGDGLRDALDPKLKQ
CCCCCHHHHHHHHHCCHHHCCCEEEEECHHHHHHHHHHHHHHCCHHHHHCCCCCCC
>Mature Secondary Structure 
SSTTLSAPAPKTPLQEFWYYFCQNRGAVIGLAFITLVFFAAVFAGWVAPFDPIEQNRSA
CCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCE
LLLPLAWMEGGNSTYLLGTDDIGRDILSRIIYGARLSVFIGLVIVILSCVFGVILGLLAG
EEEEEHEECCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YYGGVIDIVIMRFVDIMLAIPSLLLTIGVVTILGPSLINAAIAIAIVSIPSYVRLTRASV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MSEKNRDYVVASRVAGAGVLRLMFIVILPNCLAPLIVQMTMGISNAILELAALGFLGIGA
HHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
QPPTPELGTMLAESRGFMQSANWLVTIPGLAILSLVLAFNLMGDGLRDALDPKLKQ
CCCCCHHHHHHHHHCCHHHCCCEEEEECHHHHHHHHHHHHHHCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800; 8550458 [H]