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The map label for this gene is yggV [C]

Identifier: 124485476

GI number: 124485476

Start: 624459

End: 625016

Strand: Reverse

Name: yggV [C]

Synonym: Mlab_0652

Alternate gene names: 124485476

Gene position: 625016-624459 (Counterclockwise)

Preceding gene: 124485477

Following gene: 124485475

Centisome position: 34.63

GC content: 54.66

Gene sequence:

>558_bases
ATGATCACCGTTGTTACCGGAAATAAAAACAAAGCCGCGGAGGTCGCCGCATTCTTTGACGGGATCGCGGAAGTGTCCCA
CATCGCCTTCGACTGCATCGAGCCTCAGTCGGACAGCATTGCCGAAATTGCCAAGGAAAAAGCGAAGCAGGCCTACGCAG
CCCTTAAAATCCCCCTGATCGTTGACGACACAGGACTTTTCATCGAAGCACTGACCGGATTTCCCGGGCCGTACGCCGCC
TATGTTCAGGATACGCTTGGAAACGCCGGGGTTCTGCGCCTGATGGAAGGGCTTTCCGACCGCCGTGCATACTTCGCCAC
CTCGATTGCCTACATCGATGATGCAGGCATCGAAATATTCGAAGGCAGAGTCGACGGCGAGATCACCGATATTCCAAGAG
GAACGGACGGATTCGGGTATGACCCCATCTTTTCCGTTCAGGGGCGGACCCTTGCCGAGATGAACATGCATGAGAAAAAT
ACCGTTTCCCACCGCGCCCGTGCCCTGTTAGCCTTCCGCGAATGGTATATTTCGGCACGGTCTGAACGTAATCGTTAA

Upstream 100 bases:

>100_bases
CGCTCAAATCCGCATTCATCAATGGATACTGCGCGGCGTTTTCCGAAGCCGAAAACGTGATCCGGCGCGAACACGAGATC
GAACTGCGCGGGAGATACTT

Downstream 100 bases:

>100_bases
TATCAACAAGAGCATACATATTAGAACTCAATATACGGGGTTATTCATAGATGAGATTCCCAGAAGCAGAAGCAAGACTT
CTTAATGTTAAAGTTTGCAT

Product: hypothetical protein

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MITVVTGNKNKAAEVAAFFDGIAEVSHIAFDCIEPQSDSIAEIAKEKAKQAYAALKIPLIVDDTGLFIEALTGFPGPYAA
YVQDTLGNAGVLRLMEGLSDRRAYFATSIAYIDDAGIEIFEGRVDGEITDIPRGTDGFGYDPIFSVQGRTLAEMNMHEKN
TVSHRARALLAFREWYISARSERNR

Sequences:

>Translated_185_residues
MITVVTGNKNKAAEVAAFFDGIAEVSHIAFDCIEPQSDSIAEIAKEKAKQAYAALKIPLIVDDTGLFIEALTGFPGPYAA
YVQDTLGNAGVLRLMEGLSDRRAYFATSIAYIDDAGIEIFEGRVDGEITDIPRGTDGFGYDPIFSVQGRTLAEMNMHEKN
TVSHRARALLAFREWYISARSERNR
>Mature_185_residues
MITVVTGNKNKAAEVAAFFDGIAEVSHIAFDCIEPQSDSIAEIAKEKAKQAYAALKIPLIVDDTGLFIEALTGFPGPYAA
YVQDTLGNAGVLRLMEGLSDRRAYFATSIAYIDDAGIEIFEGRVDGEITDIPRGTDGFGYDPIFSVQGRTLAEMNMHEKN
TVSHRARALLAFREWYISARSERNR

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Homo sapiens, GI15626999, Length=184, Percent_Identity=36.4130434782609, Blast_Score=105, Evalue=3e-23,
Organism=Homo sapiens, GI31657144, Length=142, Percent_Identity=38.7323943661972, Blast_Score=99, Evalue=2e-21,
Organism=Escherichia coli, GI1789324, Length=184, Percent_Identity=33.695652173913, Blast_Score=89, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17556833, Length=179, Percent_Identity=37.9888268156425, Blast_Score=112, Evalue=7e-26,
Organism=Saccharomyces cerevisiae, GI6322529, Length=188, Percent_Identity=34.5744680851064, Blast_Score=94, Evalue=1e-20,
Organism=Drosophila melanogaster, GI19920712, Length=181, Percent_Identity=38.6740331491713, Blast_Score=109, Evalue=8e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 20300; Mature: 20300

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITVVTGNKNKAAEVAAFFDGIAEVSHIAFDCIEPQSDSIAEIAKEKAKQAYAALKIPLI
CEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHEEEEEE
VDDTGLFIEALTGFPGPYAAYVQDTLGNAGVLRLMEGLSDRRAYFATSIAYIDDAGIEIF
ECCCCHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHEEECCCCCEEE
EGRVDGEITDIPRGTDGFGYDPIFSVQGRTLAEMNMHEKNTVSHRARALLAFREWYISAR
ECCCCCEEECCCCCCCCCCCCCEEECCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
SERNR
CCCCC
>Mature Secondary Structure
MITVVTGNKNKAAEVAAFFDGIAEVSHIAFDCIEPQSDSIAEIAKEKAKQAYAALKIPLI
CEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHEEEEEE
VDDTGLFIEALTGFPGPYAAYVQDTLGNAGVLRLMEGLSDRRAYFATSIAYIDDAGIEIF
ECCCCHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHEEECCCCCEEE
EGRVDGEITDIPRGTDGFGYDPIFSVQGRTLAEMNMHEKNTVSHRARALLAFREWYISAR
ECCCCCEEECCCCCCCCCCCCCEEECCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
SERNR
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA