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The map label for this gene is mdtD [H]

Identifier: 124485435

GI number: 124485435

Start: 581592

End: 582986

Strand: Reverse

Name: mdtD [H]

Synonym: Mlab_0610

Alternate gene names: 124485435

Gene position: 582986-581592 (Counterclockwise)

Preceding gene: 124485436

Following gene: 124485428

Centisome position: 32.3

GC content: 51.4

Gene sequence:

>1395_bases
ATGCTGCTTTTGATTGCCGCATTTGCCGTTTTTATGGACGGACTTGACGGATCGATTGTCAACGTTGTTCTTCCGGTTAT
GGCCGCCGAGTTCGGTATCGACATCTCGGGAAGCTCGTGGATTGTAATCGCGTACCTTCTTTTCATGGCAGGATTCATTC
TTGCATTCGGGAAAGTTGCCGACAACGGAAAAATTCGTGGAGTGTTCTCAATCGGTTTTGGGATTTTCGCCCTTGGTTCT
CTGATGTGTGCTCTATCCCCGTCGCTTGAATGCATCGTCGCCGCACGTGCTCTGCAGGGGCTGGGTGCTTCGATGATCGC
AGCGGCGGCGCCTCTGCTTGTTACAAGGTTCCTGCCGAAGGAAAGACGGGGATTTGGGATGGGCGTAATTGCGACGACCG
GCGGTATCGCTCTAACCTTCGGCCCCCCTCTTGGGGGATTTATTTCGGCATACCTTTCATGGCACTGGATTTTTTTAATT
AATGTCCCAATCGGAATCGCTGCCATCCTTCTTGCAAAGCTGGCTATCCCTTCGCCGAACGGCAAGCCAGTGAACGATCA
TTTCGATAAAACAGGTACGGCGCTGATGTTTGCAGCGATTGCATCGATGATTATTTTCTTCGAACGCGGCCCAGTCCTTG
GATGGACGAATGCCACGATTCTCATCTGCGGAGCGGTATTTGCCTTCTCCTTTGCAGGGTTTTGTATCCATTCACTGCGA
AGCCCGTACCCTCTTTTGAATATCAGAATATTCCGGCACTGGAAATTTACCTCAGTCACTATTTCCTATCTTCTGACATG
TGCCGTTTTCTCAGGCGTGATGTATATGGTCCCGTATTATATGCAGACGGCGGTAGGTTTGTCGACGGTGACGTCGGGGA
TGCTTCTGATGATCGCATCGATTCTGACAGCGCTTGTTGGAATCCCTATCGGCGCATGGAGCGACAAAATCGGCTGCCGT
ACGCCCTGCATTATGGCCGCGTTGTTTCGAATATCCTTCTGTCTGATCTTCCTGCTGATAATTCCAGAGTGGGGGGCGGC
AGCAATTATTCCCGGTTTGATTTGCATGGGCCTTTCGTTTGGGATCTCGGGAGGTCCGGCGACAACCCGTATTGTCCAGT
TCTCTCCAAAAGGTGAAGACGGGATGGGGACGTCAGTCATGATCACCTCGGATTTTCTTGGAGGTGTTATAGGGGTTGCG
GCGTATGCCGTCGTTTTTTCCCTGGCAGTCCCCGGATCGGTAGGAGTCTCGGTGAGTGATCTATCATCCGCTGCATTGAC
GAGCGGATTCCATGCTACAGCCGCTTTCGGCTTGATCCTTGGAATTATAACGCTTATTCTCTCAAGCGTCGTGCCGAATC
TGATCGTGAAAAAAAGTGGGTTGGCAGACCCGTAA

Upstream 100 bases:

>100_bases
ACATCATCCCATTTCCTTTTTACTTCGCAGATTTCAAGTATTCATACTGTCAACGTGTTTAAGCGTGTATTCCGTCATCA
CAAGTCCACACCATCAGAAA

Downstream 100 bases:

>100_bases
AAAAGTTGGAGGATTTTATCCTCTCAGAATATCTTTTGCGATCCAGTCGCCGATATCCGACGTGTGCATTGAACCGCCCA
TATCTTTTGTGACCGCCTTA

Product: glyoxalase/bleomycin resistance protein/dioxygenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 464; Mature: 464

Protein sequence:

>464_residues
MLLLIAAFAVFMDGLDGSIVNVVLPVMAAEFGIDISGSSWIVIAYLLFMAGFILAFGKVADNGKIRGVFSIGFGIFALGS
LMCALSPSLECIVAARALQGLGASMIAAAAPLLVTRFLPKERRGFGMGVIATTGGIALTFGPPLGGFISAYLSWHWIFLI
NVPIGIAAILLAKLAIPSPNGKPVNDHFDKTGTALMFAAIASMIIFFERGPVLGWTNATILICGAVFAFSFAGFCIHSLR
SPYPLLNIRIFRHWKFTSVTISYLLTCAVFSGVMYMVPYYMQTAVGLSTVTSGMLLMIASILTALVGIPIGAWSDKIGCR
TPCIMAALFRISFCLIFLLIIPEWGAAAIIPGLICMGLSFGISGGPATTRIVQFSPKGEDGMGTSVMITSDFLGGVIGVA
AYAVVFSLAVPGSVGVSVSDLSSAALTSGFHATAAFGLILGIITLILSSVVPNLIVKKSGLADP

Sequences:

>Translated_464_residues
MLLLIAAFAVFMDGLDGSIVNVVLPVMAAEFGIDISGSSWIVIAYLLFMAGFILAFGKVADNGKIRGVFSIGFGIFALGS
LMCALSPSLECIVAARALQGLGASMIAAAAPLLVTRFLPKERRGFGMGVIATTGGIALTFGPPLGGFISAYLSWHWIFLI
NVPIGIAAILLAKLAIPSPNGKPVNDHFDKTGTALMFAAIASMIIFFERGPVLGWTNATILICGAVFAFSFAGFCIHSLR
SPYPLLNIRIFRHWKFTSVTISYLLTCAVFSGVMYMVPYYMQTAVGLSTVTSGMLLMIASILTALVGIPIGAWSDKIGCR
TPCIMAALFRISFCLIFLLIIPEWGAAAIIPGLICMGLSFGISGGPATTRIVQFSPKGEDGMGTSVMITSDFLGGVIGVA
AYAVVFSLAVPGSVGVSVSDLSSAALTSGFHATAAFGLILGIITLILSSVVPNLIVKKSGLADP
>Mature_464_residues
MLLLIAAFAVFMDGLDGSIVNVVLPVMAAEFGIDISGSSWIVIAYLLFMAGFILAFGKVADNGKIRGVFSIGFGIFALGS
LMCALSPSLECIVAARALQGLGASMIAAAAPLLVTRFLPKERRGFGMGVIATTGGIALTFGPPLGGFISAYLSWHWIFLI
NVPIGIAAILLAKLAIPSPNGKPVNDHFDKTGTALMFAAIASMIIFFERGPVLGWTNATILICGAVFAFSFAGFCIHSLR
SPYPLLNIRIFRHWKFTSVTISYLLTCAVFSGVMYMVPYYMQTAVGLSTVTSGMLLMIASILTALVGIPIGAWSDKIGCR
TPCIMAALFRISFCLIFLLIIPEWGAAAIIPGLICMGLSFGISGGPATTRIVQFSPKGEDGMGTSVMITSDFLGGVIGVA
AYAVVFSLAVPGSVGVSVSDLSSAALTSGFHATAAFGLILGIITLILSSVVPNLIVKKSGLADP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. TCR/tet family [H]

Homologues:

Organism=Escherichia coli, GI87081983, Length=405, Percent_Identity=30.3703703703704, Blast_Score=139, Evalue=5e-34,
Organism=Escherichia coli, GI1790195, Length=295, Percent_Identity=31.1864406779661, Blast_Score=132, Evalue=5e-32,
Organism=Escherichia coli, GI1788392, Length=301, Percent_Identity=32.5581395348837, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1788710, Length=320, Percent_Identity=30, Blast_Score=119, Evalue=6e-28,
Organism=Escherichia coli, GI1789042, Length=364, Percent_Identity=26.3736263736264, Blast_Score=114, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6325455, Length=150, Percent_Identity=33.3333333333333, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6322958, Length=229, Percent_Identity=27.9475982532751, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6319770, Length=409, Percent_Identity=24.9388753056235, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6321663, Length=150, Percent_Identity=28.6666666666667, Blast_Score=68, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6323735, Length=317, Percent_Identity=25.5520504731861, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48412; Mature: 48412

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLLIAAFAVFMDGLDGSIVNVVLPVMAAEFGIDISGSSWIVIAYLLFMAGFILAFGKVA
CHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
DNGKIRGVFSIGFGIFALGSLMCALSPSLECIVAARALQGLGASMIAAAAPLLVTRFLPK
CCCCEEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCH
ERRGFGMGVIATTGGIALTFGPPLGGFISAYLSWHWIFLINVPIGIAAILLAKLAIPSPN
HHCCCCCEEEEECCCEEEEECCCHHHHHHHHHHHHEEEEEECHHHHHHHHHHHHCCCCCC
GKPVNDHFDKTGTALMFAAIASMIIFFERGPVLGWTNATILICGAVFAFSFAGFCIHSLR
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
SPYPLLNIRIFRHWKFTSVTISYLLTCAVFSGVMYMVPYYMQTAVGLSTVTSGMLLMIAS
CCCCEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILTALVGIPIGAWSDKIGCRTPCIMAALFRISFCLIFLLIIPEWGAAAIIPGLICMGLSF
HHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHC
GISGGPATTRIVQFSPKGEDGMGTSVMITSDFLGGVIGVAAYAVVFSLAVPGSVGVSVSD
CCCCCCCCEEEEEECCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
LSSAALTSGFHATAAFGLILGIITLILSSVVPNLIVKKSGLADP
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLLLIAAFAVFMDGLDGSIVNVVLPVMAAEFGIDISGSSWIVIAYLLFMAGFILAFGKVA
CHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
DNGKIRGVFSIGFGIFALGSLMCALSPSLECIVAARALQGLGASMIAAAAPLLVTRFLPK
CCCCEEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCH
ERRGFGMGVIATTGGIALTFGPPLGGFISAYLSWHWIFLINVPIGIAAILLAKLAIPSPN
HHCCCCCEEEEECCCEEEEECCCHHHHHHHHHHHHEEEEEECHHHHHHHHHHHHCCCCCC
GKPVNDHFDKTGTALMFAAIASMIIFFERGPVLGWTNATILICGAVFAFSFAGFCIHSLR
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
SPYPLLNIRIFRHWKFTSVTISYLLTCAVFSGVMYMVPYYMQTAVGLSTVTSGMLLMIAS
CCCCEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILTALVGIPIGAWSDKIGCRTPCIMAALFRISFCLIFLLIIPEWGAAAIIPGLICMGLSF
HHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHC
GISGGPATTRIVQFSPKGEDGMGTSVMITSDFLGGVIGVAAYAVVFSLAVPGSVGVSVSD
CCCCCCCCEEEEEECCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
LSSAALTSGFHATAAFGLILGIITLILSSVVPNLIVKKSGLADP
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA