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The map label for this gene is mcp [H]

Identifier: 124265779

GI number: 124265779

Start: 614944

End: 616698

Strand: Direct

Name: mcp [H]

Synonym: Mpe_A0586

Alternate gene names: 124265779

Gene position: 614944-616698 (Clockwise)

Preceding gene: 124265778

Following gene: 124265780

Centisome position: 15.21

GC content: 70.2

Gene sequence:

>1755_bases
ATGAAACTCGACCAACTGAAGATCGGCGCCCGACTCGGGGCAGGCTTCGGCACCGTGCTGTTGTTGCTGGTGCTGATCGT
CATGCTCTCGTTCTCGCGACTCGTGATGACCGAGCGGGGCTTCGACAGCGCGCTCGACGTGGAGCATCGCGTGGCGCGGG
CCGACGAATGGAAGAACCTGACCACGCTCAACGTCAGCCGCACCATCGCGATCGTGAAGTCGGGCGGCCTGCCGCAGATG
AGCGCGTTCCTCACGCCGCAGATGAAGGACACCAGCGAGCAGATCACGCGCGTGCAGAAGGAACTGGAGGCCGAGCTGAG
CCATGAGCGCAGCAAGGCACTGTTCGCCGACATCTCCGGCAAGCGCAAGGCCTACATCGACCAGCGCGAAGCGGCGCTGG
CACTGCTGAAGGCCGGCGACGTCACGGCGGTCGAGCTGCTCCTGGAGAAGAGCCTGCTGCCGGCCTCCAAGGTCTACCTG
GCGGCCATCGAGGACTTCAGCAACTTTGAGCGCGAGCTGGCCGTGCAGAGCGCCGCTGCGGTGAAGGCCGACGTGCAGCG
CAGCAAGCTGATGCTGCTGGTGCTGGCCGGTGTGTCCATCGTCCTCGGCAGCCTGAGCGCCTGGGTCCTGACCCGGTCGG
TGACGGCGCCGCTGCGCCGCGCTGCGGCCAGCACGCAGGCGATCGCCGCCGGCGACCTGTCGCAGCCCATCGAGGCCACG
GGCCGCGACGAGGTGGCCGACCTGCAGCGCAGCCTGGGCAAGATGCAGACCTCGCTGCGCGACATGGTGAGTGCGGTGCG
CCTGAGCACCGACAGCATCACCACCGCCAGCAGCGAGATCGCGACCGGCAACCAGGACCTCAGCGCCCGCACCGAACAGA
CCGCGAGCAACCTGCAGGAAACCGCGAGCTCGATGGAGCAGCTCACCGGCACGGTCAAGCAGACCGCCGAGTCCGCCCGC
ACCGCCAACCAGCTCGCGTCGTCGGCCCAGGCCACGGCGGCCAAGGGCGGCCAGGTGGTGTCGCAGGTCGTGTCGACGAT
GGACGACATCAACGCGAGCAGCAAGAAGATCGCCGACATCATCGGCGTGATCGACGGCATCGCCTTCCAGACCAACATCC
TGGCGCTCAACGCGGCGGTGGAAGCCGCCCGTGCCGGCGAGCAGGGCCGCGGCTTCGCGGTGGTGGCCGGCGAGGTGCGC
AACCTGGCGCAGCGAAGCGCCCAGGCCGCCAAGGAGATCAAGGACCTGATCGGCGCGAGCGTCGAGCGGGTCGAGTCGGG
CAGCAAGCTGGTGGCCGATGCCGGCCGCACGATGAGCGAGATCGTGGGTTCGGTGCAGCGTGTGTCCGACATCATCTGCG
AGATCACGGCCGCCGCCGCCGAGCAGTCGGACGGCATCGGCCAGGTCAACACCGCGGTGACCAACCTCGACCAGATGACG
CAGCAGAACGCCGCGCTGGTGGAGGAGAGCGCCGCCGCCGCCGAGAGCCTGAAGGACCAGGCGATCCGTCTGGCCGCTTC
GGTCTCGGTGTTCCGCGTCGATGCGCATGCCACGGTGTCGCGGCCGGCCGCTGCCACGCCGAGCCTGCCCGCGCCCAGCG
CGCCGCGCGCACCGGTGCAGGCCGCGCCGGCACCCCAGCGCGCCGCCAAGGCGCCGCCGGTGCTGCGCGATGCCGTGGCC
GCCGCCGGGCCGGCCCCGGTCGTGGCGGCTGCCGCGGCGACCGCCACGCCGGGCGACGACTGGGAAACCTTCTGA

Upstream 100 bases:

>100_bases
TCGCCCTCATCCTCGACGTGGGATCGCTGGTGCGGCGCTCGCGCCACTGAGGGGCCGTCTCCGCCCGAACCGATTCCCGC
TCTCCCGGAAAGACTCCAAG

Downstream 100 bases:

>100_bases
TCCGGGTCCGGATGCGCACGCAGGCCTTCAGTCCGCGCCGCAACTGCCGTAAACCACTCTGACATCCCGCGCAGCGCCGC
GTCCGCGGCGCTCCGACACC

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 584; Mature: 584

Protein sequence:

>584_residues
MKLDQLKIGARLGAGFGTVLLLLVLIVMLSFSRLVMTERGFDSALDVEHRVARADEWKNLTTLNVSRTIAIVKSGGLPQM
SAFLTPQMKDTSEQITRVQKELEAELSHERSKALFADISGKRKAYIDQREAALALLKAGDVTAVELLLEKSLLPASKVYL
AAIEDFSNFERELAVQSAAAVKADVQRSKLMLLVLAGVSIVLGSLSAWVLTRSVTAPLRRAAASTQAIAAGDLSQPIEAT
GRDEVADLQRSLGKMQTSLRDMVSAVRLSTDSITTASSEIATGNQDLSARTEQTASNLQETASSMEQLTGTVKQTAESAR
TANQLASSAQATAAKGGQVVSQVVSTMDDINASSKKIADIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVR
NLAQRSAQAAKEIKDLIGASVERVESGSKLVADAGRTMSEIVGSVQRVSDIICEITAAAAEQSDGIGQVNTAVTNLDQMT
QQNAALVEESAAAAESLKDQAIRLAASVSVFRVDAHATVSRPAAATPSLPAPSAPRAPVQAAPAPQRAAKAPPVLRDAVA
AAGPAPVVAAAAATATPGDDWETF

Sequences:

>Translated_584_residues
MKLDQLKIGARLGAGFGTVLLLLVLIVMLSFSRLVMTERGFDSALDVEHRVARADEWKNLTTLNVSRTIAIVKSGGLPQM
SAFLTPQMKDTSEQITRVQKELEAELSHERSKALFADISGKRKAYIDQREAALALLKAGDVTAVELLLEKSLLPASKVYL
AAIEDFSNFERELAVQSAAAVKADVQRSKLMLLVLAGVSIVLGSLSAWVLTRSVTAPLRRAAASTQAIAAGDLSQPIEAT
GRDEVADLQRSLGKMQTSLRDMVSAVRLSTDSITTASSEIATGNQDLSARTEQTASNLQETASSMEQLTGTVKQTAESAR
TANQLASSAQATAAKGGQVVSQVVSTMDDINASSKKIADIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVR
NLAQRSAQAAKEIKDLIGASVERVESGSKLVADAGRTMSEIVGSVQRVSDIICEITAAAAEQSDGIGQVNTAVTNLDQMT
QQNAALVEESAAAAESLKDQAIRLAASVSVFRVDAHATVSRPAAATPSLPAPSAPRAPVQAAPAPQRAAKAPPVLRDAVA
AAGPAPVVAAAAATATPGDDWETF
>Mature_584_residues
MKLDQLKIGARLGAGFGTVLLLLVLIVMLSFSRLVMTERGFDSALDVEHRVARADEWKNLTTLNVSRTIAIVKSGGLPQM
SAFLTPQMKDTSEQITRVQKELEAELSHERSKALFADISGKRKAYIDQREAALALLKAGDVTAVELLLEKSLLPASKVYL
AAIEDFSNFERELAVQSAAAVKADVQRSKLMLLVLAGVSIVLGSLSAWVLTRSVTAPLRRAAASTQAIAAGDLSQPIEAT
GRDEVADLQRSLGKMQTSLRDMVSAVRLSTDSITTASSEIATGNQDLSARTEQTASNLQETASSMEQLTGTVKQTAESAR
TANQLASSAQATAAKGGQVVSQVVSTMDDINASSKKIADIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVR
NLAQRSAQAAKEIKDLIGASVERVESGSKLVADAGRTMSEIVGSVQRVSDIICEITAAAAEQSDGIGQVNTAVTNLDQMT
QQNAALVEESAAAAESLKDQAIRLAASVSVFRVDAHATVSRPAAATPSLPAPSAPRAPVQAAPAPQRAAKAPPVLRDAVA
AAGPAPVVAAAAATATPGDDWETF

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=334, Percent_Identity=59.5808383233533, Blast_Score=330, Evalue=2e-91,
Organism=Escherichia coli, GI2367378, Length=348, Percent_Identity=58.6206896551724, Blast_Score=329, Evalue=3e-91,
Organism=Escherichia coli, GI1788194, Length=333, Percent_Identity=54.3543543543543, Blast_Score=319, Evalue=3e-88,
Organism=Escherichia coli, GI1787690, Length=417, Percent_Identity=47.0023980815348, Blast_Score=316, Evalue=2e-87,
Organism=Escherichia coli, GI1789453, Length=321, Percent_Identity=41.1214953271028, Blast_Score=233, Evalue=3e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 60894; Mature: 60894

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLDQLKIGARLGAGFGTVLLLLVLIVMLSFSRLVMTERGFDSALDVEHRVARADEWKNL
CCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCC
TTLNVSRTIAIVKSGGLPQMSAFLTPQMKDTSEQITRVQKELEAELSHERSKALFADISG
EEEEHHHEEEEEECCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
KRKAYIDQREAALALLKAGDVTAVELLLEKSLLPASKVYLAAIEDFSNFERELAVQSAAA
CHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VKADVQRSKLMLLVLAGVSIVLGSLSAWVLTRSVTAPLRRAAASTQAIAAGDLSQPIEAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHC
GRDEVADLQRSLGKMQTSLRDMVSAVRLSTDSITTASSEIATGNQDLSARTEQTASNLQE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCCHHHHHHHHHHHHHH
TASSMEQLTGTVKQTAESARTANQLASSAQATAAKGGQVVSQVVSTMDDINASSKKIADI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHH
IGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNLAQRSAQAAKEIKDLIGAS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
VERVESGSKLVADAGRTMSEIVGSVQRVSDIICEITAAAAEQSDGIGQVNTAVTNLDQMT
HHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
QQNAALVEESAAAAESLKDQAIRLAASVSVFRVDAHATVSRPAAATPSLPAPSAPRAPVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCHHCCCCCCCCCCCCCCCCCCCCCC
AAPAPQRAAKAPPVLRDAVAAAGPAPVVAAAAATATPGDDWETF
CCCCCHHHCCCCCHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MKLDQLKIGARLGAGFGTVLLLLVLIVMLSFSRLVMTERGFDSALDVEHRVARADEWKNL
CCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCC
TTLNVSRTIAIVKSGGLPQMSAFLTPQMKDTSEQITRVQKELEAELSHERSKALFADISG
EEEEHHHEEEEEECCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
KRKAYIDQREAALALLKAGDVTAVELLLEKSLLPASKVYLAAIEDFSNFERELAVQSAAA
CHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VKADVQRSKLMLLVLAGVSIVLGSLSAWVLTRSVTAPLRRAAASTQAIAAGDLSQPIEAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHC
GRDEVADLQRSLGKMQTSLRDMVSAVRLSTDSITTASSEIATGNQDLSARTEQTASNLQE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCCHHHHHHHHHHHHHH
TASSMEQLTGTVKQTAESARTANQLASSAQATAAKGGQVVSQVVSTMDDINASSKKIADI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHH
IGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNLAQRSAQAAKEIKDLIGAS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
VERVESGSKLVADAGRTMSEIVGSVQRVSDIICEITAAAAEQSDGIGQVNTAVTNLDQMT
HHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
QQNAALVEESAAAAESLKDQAIRLAASVSVFRVDAHATVSRPAAATPSLPAPSAPRAPVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCHHCCCCCCCCCCCCCCCCCCCCCC
AAPAPQRAAKAPPVLRDAVAAAGPAPVVAAAAATATPGDDWETF
CCCCCHHHCCCCCHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2496104 [H]