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The map label for this gene is cheW [H]

Identifier: 124265780

GI number: 124265780

Start: 616817

End: 617341

Strand: Direct

Name: cheW [H]

Synonym: Mpe_A0587

Alternate gene names: 124265780

Gene position: 616817-617341 (Clockwise)

Preceding gene: 124265779

Following gene: 124265781

Centisome position: 15.25

GC content: 67.62

Gene sequence:

>525_bases
ATGGACATGATCGACGCCACCCAAGTGGCCCGCCACGAAGCCCAGCGCCAGGGCAACCGCGCCGGCGCTGGCGCCCAGCC
GGGCCGTGAGTACCTCAGCTTCCGCCTCGGCACCGAGGAGTACGGCATCGACATCCTGAAGGTGCAGGAGATCCGCAGCT
ACGAGCCGCCGACCCGCATCGCCAACGCCCCGAGCTTCCTCAAGGGCGTGATCAACCTGCGCGGCGTGATCGTGCCGGTG
GTCGATCTGCGCGTGAAGTTCGGCTGCGATGCTCAGATCACGCCCATCACGGCGGTGATCGTGCTGGCTGTCAAGGGCCG
CGTCATCGGCGCCGTGGTCGACTCGGTGAGCGACGTGCTGGACCTGCCGCACGACGCCATCAAGCCGGCACCGTCGATGG
GCGCGGTCGTCGACACCAGCCACCTGATCGGCATCGCCACCGTGGCCGAACGCATGCTGATCCTGATGGACATCGAATCG
CTGATGACGAGCGCCGAGCTCGGCGTGATCGACGCGGTGGGCTGA

Upstream 100 bases:

>100_bases
CGCAGGCCTTCAGTCCGCGCCGCAACTGCCGTAAACCACTCTGACATCCCGCGCAGCGCCGCGTCCGCGGCGCTCCGACA
CCGCACCGAGAGGATCCACC

Downstream 100 bases:

>100_bases
GTCCGGCCACGCGCGGCGGCTCCGCCGCGCTCCCCGCCGACGGCGCCCCGAGGGGCGCCGTTGCTCATGGGGCCGACCGG
AGGCGCAGCGCGGACCCGCG

Product: CheW protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 174; Mature: 174

Protein sequence:

>174_residues
MDMIDATQVARHEAQRQGNRAGAGAQPGREYLSFRLGTEEYGIDILKVQEIRSYEPPTRIANAPSFLKGVINLRGVIVPV
VDLRVKFGCDAQITPITAVIVLAVKGRVIGAVVDSVSDVLDLPHDAIKPAPSMGAVVDTSHLIGIATVAERMLILMDIES
LMTSAELGVIDAVG

Sequences:

>Translated_174_residues
MDMIDATQVARHEAQRQGNRAGAGAQPGREYLSFRLGTEEYGIDILKVQEIRSYEPPTRIANAPSFLKGVINLRGVIVPV
VDLRVKFGCDAQITPITAVIVLAVKGRVIGAVVDSVSDVLDLPHDAIKPAPSMGAVVDTSHLIGIATVAERMLILMDIES
LMTSAELGVIDAVG
>Mature_174_residues
MDMIDATQVARHEAQRQGNRAGAGAQPGREYLSFRLGTEEYGIDILKVQEIRSYEPPTRIANAPSFLKGVINLRGVIVPV
VDLRVKFGCDAQITPITAVIVLAVKGRVIGAVVDSVSDVLDLPHDAIKPAPSMGAVVDTSHLIGIATVAERMLILMDIES
LMTSAELGVIDAVG

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. It physically bridges CheA to the MCPs (methyl-accepting chemotaxis proteins) to allow regulated phosphotransfer to CheY and CheB [H]

COG id: COG0835

COG function: function code NT; Chemotaxis signal transduction protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cheW-like domain [H]

Homologues:

Organism=Escherichia coli, GI1788196, Length=156, Percent_Identity=53.2051282051282, Blast_Score=163, Evalue=6e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002545 [H]

Pfam domain/function: PF01584 CheW [H]

EC number: NA

Molecular weight: Translated: 18527; Mature: 18527

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS50851 CHEW

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDMIDATQVARHEAQRQGNRAGAGAQPGREYLSFRLGTEEYGIDILKVQEIRSYEPPTRI
CCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHEEECCCHHHCEEEEEEHHHHCCCCCHHH
ANAPSFLKGVINLRGVIVPVVDLRVKFGCDAQITPITAVIVLAVKGRVIGAVVDSVSDVL
CCCHHHHHHHHHHHHHEEEHEEEEEEECCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHH
DLPHDAIKPAPSMGAVVDTSHLIGIATVAERMLILMDIESLMTSAELGVIDAVG
HCCHHHHCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCC
>Mature Secondary Structure
MDMIDATQVARHEAQRQGNRAGAGAQPGREYLSFRLGTEEYGIDILKVQEIRSYEPPTRI
CCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHEEECCCHHHCEEEEEEHHHHCCCCCHHH
ANAPSFLKGVINLRGVIVPVVDLRVKFGCDAQITPITAVIVLAVKGRVIGAVVDSVSDVL
CCCHHHHHHHHHHHHHEEEHEEEEEEECCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHH
DLPHDAIKPAPSMGAVVDTSHLIGIATVAERMLILMDIESLMTSAELGVIDAVG
HCCHHHHCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]