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The map label for this gene is qseD [H]

Identifier: 124265635

GI number: 124265635

Start: 480929

End: 481900

Strand: Direct

Name: qseD [H]

Synonym: Mpe_A0442

Alternate gene names: 124265635

Gene position: 480929-481900 (Clockwise)

Preceding gene: 124265634

Following gene: 124265636

Centisome position: 11.89

GC content: 70.99

Gene sequence:

>972_bases
GTGGAGACCAAGTGGCTGGAAGACTTCGTGAGCCTGGCCGAGACGCGCAGCTTCTCGCGCTCGGCCCAACTGCGCCACGT
CACCCAGCCGGCGTTCTCGCGCCGGATCCAGGCGCTGGAGGCCTGGGCCGGCACCGATCTGGTCGACCGCTCGTCCTACC
CGACCCGCCTCACGCCGGCCGGCGAGAGCTTCCACGCCCAGGCCCTGGAGATCCTGGTGGCGCTGCAGGCCACCCGCAAC
CTGCTGCGCGGTCACCGGGCCGCGGGGCCGGACATGATCGAGTTCGCGGTGCCCCACACGCTGGCATTCGCCTTCTTTCC
GCACTGGATCATGGAGCTCAACCGCGACCTGAAGCGCGAATCCGGTGCGCTGAAGAGCCGCCTGATCGCACTCAATGTGC
ACGATGCGGTGCTGCGCCTGACCGAGGGCAGCTGCGACCTGCTGATCGCCTACCACCACCCGGCGCAGCCGCTGCAGCTC
AACACCGACCGCTACGAGATGCTGACGCTCGGCGAGGAGTCGCTGCGCGCCTACGCCAAGGCCGGGCCGGACGGCGAGCC
GCTGTTCCGCCTGCCCGGACGTGAGCGCGAGCGGGTGCCCTTCCTGGGCTATGCCAGCGGCGCCTACCTCGGGCAGCTGG
TGGACCTGATCATCAAGCAGACGCCGCTGCCGGTGCTGCTCGACCCGATCTACGAGACCGACATGGCCGAGGGCCTGAAG
GCGATGGCGCTCGAGGGGCATGGCCTGGCCTTCCTGCCGGCCAGTTCGGTGCGCAAGGAGCTGAAGACGCGCAAGCTGGT
GCCGGCCGCGCCGTCGGGCAGCTTCGAACTCAGCATGGAGGTGCGCATCTACCGCGAGCGCCCCGAGGTCGCGAAGCACG
TCAAGCCGGGCGTCCGGGCGCTGTGGGCACACCTGTTGCAGGCCGGCGCCGGGCCGCTGTCGGCCGGCGCGGCGCCGCGG
GCAGCGGCCTGA

Upstream 100 bases:

>100_bases
TGGCGACGCGACCGTGGAGGTGGAGTTGGTGGAGCTGAAGGAAGCCGTGCTCCGTTGAACCGGCGCCGCGAAGCGCCGGG
CGCTGGCTACACTGCGGCGC

Downstream 100 bases:

>100_bases
GCCGCGCGGGGTATGGCACGAACCCTGCTCGCGTTCCGGGGCGATGCACCTGTGGCGACCCCGTATGGCCTGCACGCCGA
GCCTCCTGTAGATTTTTGCT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Quorum-sensing regulator protein D [H]

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
METKWLEDFVSLAETRSFSRSAQLRHVTQPAFSRRIQALEAWAGTDLVDRSSYPTRLTPAGESFHAQALEILVALQATRN
LLRGHRAAGPDMIEFAVPHTLAFAFFPHWIMELNRDLKRESGALKSRLIALNVHDAVLRLTEGSCDLLIAYHHPAQPLQL
NTDRYEMLTLGEESLRAYAKAGPDGEPLFRLPGRERERVPFLGYASGAYLGQLVDLIIKQTPLPVLLDPIYETDMAEGLK
AMALEGHGLAFLPASSVRKELKTRKLVPAAPSGSFELSMEVRIYRERPEVAKHVKPGVRALWAHLLQAGAGPLSAGAAPR
AAA

Sequences:

>Translated_323_residues
METKWLEDFVSLAETRSFSRSAQLRHVTQPAFSRRIQALEAWAGTDLVDRSSYPTRLTPAGESFHAQALEILVALQATRN
LLRGHRAAGPDMIEFAVPHTLAFAFFPHWIMELNRDLKRESGALKSRLIALNVHDAVLRLTEGSCDLLIAYHHPAQPLQL
NTDRYEMLTLGEESLRAYAKAGPDGEPLFRLPGRERERVPFLGYASGAYLGQLVDLIIKQTPLPVLLDPIYETDMAEGLK
AMALEGHGLAFLPASSVRKELKTRKLVPAAPSGSFELSMEVRIYRERPEVAKHVKPGVRALWAHLLQAGAGPLSAGAAPR
AAA
>Mature_323_residues
METKWLEDFVSLAETRSFSRSAQLRHVTQPAFSRRIQALEAWAGTDLVDRSSYPTRLTPAGESFHAQALEILVALQATRN
LLRGHRAAGPDMIEFAVPHTLAFAFFPHWIMELNRDLKRESGALKSRLIALNVHDAVLRLTEGSCDLLIAYHHPAQPLQL
NTDRYEMLTLGEESLRAYAKAGPDGEPLFRLPGRERERVPFLGYASGAYLGQLVDLIIKQTPLPVLLDPIYETDMAEGLK
AMALEGHGLAFLPASSVRKELKTRKLVPAAPSGSFELSMEVRIYRERPEVAKHVKPGVRALWAHLLQAGAGPLSAGAAPR
AAA

Specific function: Down-regulates expression of the flagellar regulon, decreasing motility [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790783, Length=268, Percent_Identity=31.7164179104478, Blast_Score=134, Evalue=1e-32,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35665; Mature: 35665

Theoretical pI: Translated: 8.92; Mature: 8.92

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METKWLEDFVSLAETRSFSRSAQLRHVTQPAFSRRIQALEAWAGTDLVDRSSYPTRLTPA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
GESFHAQALEILVALQATRNLLRGHRAAGPDMIEFAVPHTLAFAFFPHWIMELNRDLKRE
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SGALKSRLIALNVHDAVLRLTEGSCDLLIAYHHPAQPLQLNTDRYEMLTLGEESLRAYAK
HHHHHHEEEEEEEHHHHHEEECCCCEEEEEECCCCCCEEECCCCEEEEECCHHHHHHHHH
AGPDGEPLFRLPGRERERVPFLGYASGAYLGQLVDLIIKQTPLPVLLDPIYETDMAEGLK
CCCCCCCEEECCCCCCCCCCEEECCCHHHHHHHHHHHHHCCCCCCEECHHHHHHHHHHHH
AMALEGHGLAFLPASSVRKELKTRKLVPAAPSGSFELSMEVRIYRERPEVAKHVKPGVRA
HEEECCCCEEEECHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEECCCHHHHHHCCHHHHH
LWAHLLQAGAGPLSAGAAPRAAA
HHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
METKWLEDFVSLAETRSFSRSAQLRHVTQPAFSRRIQALEAWAGTDLVDRSSYPTRLTPA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
GESFHAQALEILVALQATRNLLRGHRAAGPDMIEFAVPHTLAFAFFPHWIMELNRDLKRE
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SGALKSRLIALNVHDAVLRLTEGSCDLLIAYHHPAQPLQLNTDRYEMLTLGEESLRAYAK
HHHHHHEEEEEEEHHHHHEEECCCCEEEEEECCCCCCEEECCCCEEEEECCHHHHHHHHH
AGPDGEPLFRLPGRERERVPFLGYASGAYLGQLVDLIIKQTPLPVLLDPIYETDMAEGLK
CCCCCCCEEECCCCCCCCCCEEECCCHHHHHHHHHHHHHCCCCCCEECHHHHHHHHHHHH
AMALEGHGLAFLPASSVRKELKTRKLVPAAPSGSFELSMEVRIYRERPEVAKHVKPGVRA
HEEECCCCEEEECHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEECCCHHHHHHCCHHHHH
LWAHLLQAGAGPLSAGAAPRAAA
HHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 7876157 [H]