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The map label for this gene is mhpD2 [H]

Identifier: 124265601

GI number: 124265601

Start: 442622

End: 443452

Strand: Direct

Name: mhpD2 [H]

Synonym: Mpe_A0408

Alternate gene names: 124265601

Gene position: 442622-443452 (Clockwise)

Preceding gene: 124265598

Following gene: 124265603

Centisome position: 10.94

GC content: 71.96

Gene sequence:

>831_bases
ATGTCGATGACCATCGCACCGCCTTCTCTCGATGCCCTGGCTCGGCAGATCCAGACCGCACAGGACGCGACCCGGCAGAT
CGAGCCCTTCACGTCGCAGCTCGACGGCTTCGACGTGCCGGCCGCGTACGCGGTGGCGCAGCTCGTGCACGAGGCACGGC
TGCGGGAAGGCGCGCGCGCGATCGGTCGCAAGATCGGCTTCACCAACCCGGACATGTGGTCGCTGTACGGCGTGCGCGAC
CCGGTATGGGCCCACGTCTACGACCGGACCGTGGTGCGCGTGGCGGGCGGACGGCACGTGTGCCGGCTGGCGCCGTTCAC
CGAGCCGAAGATCGAGCCCGAGATCGTGCTGCACTTCCATCGCGCGCCGCCGGCGGGTGCCGACGCGGCCGCACTGCTGG
ACTGCATCGACTGGGTGGCGCATGCGTTCGAGATCGTGCAGTCGCATTTCCCGGGCTGGAAATTCCGCGCTGCCGATACG
GTGGCCGACGCCGCGCTGCACGGCGCGCTGCTGGTCGGCGAGCCGCAGCCGGTGGCTCGCCTGCAGCCAGGCCTGCGCTC
GGCGTTGGCGGCCTTTTCCTTGGAGCTGGTGTGCGACGGCGCGGTGCGCGAGGTGGGCGTGGGCGCCAACGTGCTGGGCA
GCCCGCTGGCCGCGCTGGCGCACCTGGCCGGCGTGCTGTCGCGTCAGCCGCAGGCGCTGCCGCTGCAGGCCGGCGAACTG
GTGACCACCGGCACGCTCACCACCGCGCAGCCGGTGCGTGCGGGGCAGACCTGGCACACGGTGCTGCGTGGCATCGATCT
GCCGGGGCTGGCGGTCGAGTTCGTCGACTGA

Upstream 100 bases:

>100_bases
ATCAAGACTGCGGTTCGAACAGGAAAAGGGATTGACTTCGTTCGACCGCCGCCGCTAGCGTGCCGCTGTCGATTTCGAGC
GACGCCTCGGGGATGCACGC

Downstream 100 bases:

>100_bases
CGTGCCCGCGGCGCGGTGCGGCGCCGCGGGGTTCTCGGCGGCTCCTCAGCCCAGCGGCGGATTGGCCGGCATGCGGGCCC
GGCTCGGATCCTGCGCCACC

Product: putative decarboxylase

Products: NA

Alternate protein names: 2-hydroxypentadienoic acid hydratase 2 [H]

Number of amino acids: Translated: 276; Mature: 275

Protein sequence:

>276_residues
MSMTIAPPSLDALARQIQTAQDATRQIEPFTSQLDGFDVPAAYAVAQLVHEARLREGARAIGRKIGFTNPDMWSLYGVRD
PVWAHVYDRTVVRVAGGRHVCRLAPFTEPKIEPEIVLHFHRAPPAGADAAALLDCIDWVAHAFEIVQSHFPGWKFRAADT
VADAALHGALLVGEPQPVARLQPGLRSALAAFSLELVCDGAVREVGVGANVLGSPLAALAHLAGVLSRQPQALPLQAGEL
VTTGTLTTAQPVRAGQTWHTVLRGIDLPGLAVEFVD

Sequences:

>Translated_276_residues
MSMTIAPPSLDALARQIQTAQDATRQIEPFTSQLDGFDVPAAYAVAQLVHEARLREGARAIGRKIGFTNPDMWSLYGVRD
PVWAHVYDRTVVRVAGGRHVCRLAPFTEPKIEPEIVLHFHRAPPAGADAAALLDCIDWVAHAFEIVQSHFPGWKFRAADT
VADAALHGALLVGEPQPVARLQPGLRSALAAFSLELVCDGAVREVGVGANVLGSPLAALAHLAGVLSRQPQALPLQAGEL
VTTGTLTTAQPVRAGQTWHTVLRGIDLPGLAVEFVD
>Mature_275_residues
SMTIAPPSLDALARQIQTAQDATRQIEPFTSQLDGFDVPAAYAVAQLVHEARLREGARAIGRKIGFTNPDMWSLYGVRDP
VWAHVYDRTVVRVAGGRHVCRLAPFTEPKIEPEIVLHFHRAPPAGADAAALLDCIDWVAHAFEIVQSHFPGWKFRAADTV
ADAALHGALLVGEPQPVARLQPGLRSALAAFSLELVCDGAVREVGVGANVLGSPLAALAHLAGVLSRQPQALPLQAGELV
TTGTLTTAQPVRAGQTWHTVLRGIDLPGLAVEFVD

Specific function: Catalyzes the conversion of 2-hydroxypentadienoic acid (enolic form of 2-oxopent-4-enoate) to 4-hydroxy-2-ketopentanoic acid [H]

COG id: COG3971

COG function: function code Q; 2-keto-4-pentenoate hydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hydratase/decarboxylase family. MhpD subfamily [H]

Homologues:

Organism=Escherichia coli, GI87081722, Length=258, Percent_Identity=28.2945736434109, Blast_Score=93, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: =4.2.1.80 [H]

Molecular weight: Translated: 29463; Mature: 29332

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMTIAPPSLDALARQIQTAQDATRQIEPFTSQLDGFDVPAAYAVAQLVHEARLREGARA
CCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
IGRKIGFTNPDMWSLYGVRDPVWAHVYDRTVVRVAGGRHVCRLAPFTEPKIEPEIVLHFH
HHHHCCCCCCCCEEECCCCCCHHHHHHHCEEEEECCCCEEEEECCCCCCCCCCEEEEEEE
RAPPAGADAAALLDCIDWVAHAFEIVQSHFPGWKFRAADTVADAALHGALLVGEPQPVAR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHCEEEECCCCCHHH
LQPGLRSALAAFSLELVCDGAVREVGVGANVLGSPLAALAHLAGVLSRQPQALPLQAGEL
HCHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCE
VTTGTLTTAQPVRAGQTWHTVLRGIDLPGLAVEFVD
EECCCCCCCCCHHCCHHHHHHHHCCCCCCCEEEECC
>Mature Secondary Structure 
SMTIAPPSLDALARQIQTAQDATRQIEPFTSQLDGFDVPAAYAVAQLVHEARLREGARA
CCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
IGRKIGFTNPDMWSLYGVRDPVWAHVYDRTVVRVAGGRHVCRLAPFTEPKIEPEIVLHFH
HHHHCCCCCCCCEEECCCCCCHHHHHHHCEEEEECCCCEEEEECCCCCCCCCCEEEEEEE
RAPPAGADAAALLDCIDWVAHAFEIVQSHFPGWKFRAADTVADAALHGALLVGEPQPVAR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHCEEEECCCCCHHH
LQPGLRSALAAFSLELVCDGAVREVGVGANVLGSPLAALAHLAGVLSRQPQALPLQAGEL
HCHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCE
VTTGTLTTAQPVRAGQTWHTVLRGIDLPGLAVEFVD
EECCCCCCCCCHHCCHHHHHHHHCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA