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The map label for this gene is exaA [H]

Identifier: 124265534

GI number: 124265534

Start: 374684

End: 376372

Strand: Direct

Name: exaA [H]

Synonym: Mpe_A0341

Alternate gene names: 124265534

Gene position: 374684-376372 (Clockwise)

Preceding gene: 124265532

Following gene: 124265535

Centisome position: 9.26

GC content: 67.97

Gene sequence:

>1689_bases
ATGAAGCGGGATTTCGCGAGGGCCGTGCTCGGCGTGGCCCTGGCATGTCTGGCGCCCCTGGCGCTGGCGCAGACGATCGA
CGACCTCAAGCGCGACGCGACGACGCCCGGCGACGTGACGACCTACGGCATGGGCTGGGGGCAGCAGCGCTACTCGGCGC
TGGCCAAGATCAACAAGACCACCGTCAAGCGCCTGGTGCCGGCCTGGAACCTTAGCCTCGACAACTCCGCGAACGCCTCG
ACGCAGCCGCTGCTGATCGGCGGCGTGATGTACGTGTCGACGCACAACGCCACGGTGGCGATCGACGCCGAGAGCGGTCG
CCAGAAGTGGAAGGTCGCCATCGACCTGCCGGCCGACGTGAACGGCTACCTCTGCTGCGGCATCCAGAGCCGCGGCATGG
CCGCGCTCGATGGCGTGCTCTACCGCACCACCATCGATGCCCACGTGCTGGCCATCGACATGGCCAGCGGGAAGACGCTG
TGGAAGCAGAAGGCGGCCGACTACAAGCAGGGCTACAGCATGACCCACGCGCCGCTGGTCGCCGGCGGCGTGCTGATCAC
CGGCATCTCCGGCGGCGAGTACGGCACGCGTGGCTTCCTCGATGGCTGGGACCTGAAGACCGGCGAGAAGAAGTGGCGCA
CCTGGACCGTGCCCGCTCCCGGCGAGCCCGGCTCGGAGACCTGGAACGCCGACCGCCACGACAAGGGCGGTGCGCCCACC
TGGCTGACCGGCACCTACGACCCGGAGCTCAACCTCGTCTACTGGGGCACCGGCAACGGCGGGCCGTGGAACCCGGCGTG
GCGCGGCAAGGATTCGCTCTACATCTGCTCCATCCTCGCGCTCGACCCGGCCACCGGCAAGATCGTCTGGCACTATCAGA
CCTCGCCCGGCGACCCCTACGACTACGACGCCACCAACGAGCTGGTGCTGGGCGAACTGCCGGTGAACGGCGCCGCCCGC
AAGGTGCTGATGCAGGCCAACCGCAACGGCTACTTCTACGTGCTCGACCGCAGCAACGGCAAGCTGCTATCGGCCACGCA
GTTCGCGCAGAAGGTCAACTGGGCGAGCGGCATCGACATGAAGACCGGCCGCCCCATCGACACCGAGATGACGAAGGCAG
TGCGGTCCAATGTCGAGAGCAAGGACTTCATCGAGGCCTGGCCCAGTGCCTTCGGTGCGAAGAACTGGATGCCGATGAGC
TTCGACCCGCTGAAGAAGCGCGTCTACCTGAACACGCTCAACTTCGGCATGAAGGTCAAGTACGGCACCCCGGCCTACCG
CCAGGGGGCCTGGTACCTGGGGCTCGAACTCGGGGGGTGGGTCGATCCGGACGGAGGCATGCGTGGCGCGCTGGTCGCCT
GGGATCCCACCACCGGCAGGAAGCTGTGGGAGAGCCCGACCGCCGCGCCGTACTGGAGCGGCGTGCTCTCCACCGCTGGC
GGGCTGGTGTTCACCGGCGCGCAGACCGGCGAGTTCATGGCCTTCGACGCCGACACCGGCACGAAGCTGTGGCAGTTCCA
GACCGGCTCGGGCATCTCCGGCCTGCCGATCACCTGGGAACTCAAGGGCCAGCAGTACGTCACCGTGACCAGCGGCGCCG
CCACCGTGTACGGCTTCCTCGGCGGTGATGCCAAGCTGGCGCAGGTGCCGGCGGGCTCGTCGGTGTGGACCTTCAGGCTG
ATCGACTGA

Upstream 100 bases:

>100_bases
GAAACTACTTGATTGGGCTGCCTGGGAGGCAAAACCTATCGTTCGCCCTGCATTCTGAGGCTGCGGCATGTCGTCGGGCC
GTCGCAATGGGAGACGAAGG

Downstream 100 bases:

>100_bases
TGCCGGCCGCGATGACCCGCGCCCGTGCGGCCGTGTTCGCCGCGCTGCTGGCGGCCGTTCTGCTGCCGGGGCCGGTGGCC
CGAGCGCAGGCGCCCGAAGG

Product: putative quinoprotein ethanol dehydrogenase

Products: NA

Alternate protein names: QEDH [H]

Number of amino acids: Translated: 562; Mature: 562

Protein sequence:

>562_residues
MKRDFARAVLGVALACLAPLALAQTIDDLKRDATTPGDVTTYGMGWGQQRYSALAKINKTTVKRLVPAWNLSLDNSANAS
TQPLLIGGVMYVSTHNATVAIDAESGRQKWKVAIDLPADVNGYLCCGIQSRGMAALDGVLYRTTIDAHVLAIDMASGKTL
WKQKAADYKQGYSMTHAPLVAGGVLITGISGGEYGTRGFLDGWDLKTGEKKWRTWTVPAPGEPGSETWNADRHDKGGAPT
WLTGTYDPELNLVYWGTGNGGPWNPAWRGKDSLYICSILALDPATGKIVWHYQTSPGDPYDYDATNELVLGELPVNGAAR
KVLMQANRNGYFYVLDRSNGKLLSATQFAQKVNWASGIDMKTGRPIDTEMTKAVRSNVESKDFIEAWPSAFGAKNWMPMS
FDPLKKRVYLNTLNFGMKVKYGTPAYRQGAWYLGLELGGWVDPDGGMRGALVAWDPTTGRKLWESPTAAPYWSGVLSTAG
GLVFTGAQTGEFMAFDADTGTKLWQFQTGSGISGLPITWELKGQQYVTVTSGAATVYGFLGGDAKLAQVPAGSSVWTFRL
ID

Sequences:

>Translated_562_residues
MKRDFARAVLGVALACLAPLALAQTIDDLKRDATTPGDVTTYGMGWGQQRYSALAKINKTTVKRLVPAWNLSLDNSANAS
TQPLLIGGVMYVSTHNATVAIDAESGRQKWKVAIDLPADVNGYLCCGIQSRGMAALDGVLYRTTIDAHVLAIDMASGKTL
WKQKAADYKQGYSMTHAPLVAGGVLITGISGGEYGTRGFLDGWDLKTGEKKWRTWTVPAPGEPGSETWNADRHDKGGAPT
WLTGTYDPELNLVYWGTGNGGPWNPAWRGKDSLYICSILALDPATGKIVWHYQTSPGDPYDYDATNELVLGELPVNGAAR
KVLMQANRNGYFYVLDRSNGKLLSATQFAQKVNWASGIDMKTGRPIDTEMTKAVRSNVESKDFIEAWPSAFGAKNWMPMS
FDPLKKRVYLNTLNFGMKVKYGTPAYRQGAWYLGLELGGWVDPDGGMRGALVAWDPTTGRKLWESPTAAPYWSGVLSTAG
GLVFTGAQTGEFMAFDADTGTKLWQFQTGSGISGLPITWELKGQQYVTVTSGAATVYGFLGGDAKLAQVPAGSSVWTFRL
ID
>Mature_562_residues
MKRDFARAVLGVALACLAPLALAQTIDDLKRDATTPGDVTTYGMGWGQQRYSALAKINKTTVKRLVPAWNLSLDNSANAS
TQPLLIGGVMYVSTHNATVAIDAESGRQKWKVAIDLPADVNGYLCCGIQSRGMAALDGVLYRTTIDAHVLAIDMASGKTL
WKQKAADYKQGYSMTHAPLVAGGVLITGISGGEYGTRGFLDGWDLKTGEKKWRTWTVPAPGEPGSETWNADRHDKGGAPT
WLTGTYDPELNLVYWGTGNGGPWNPAWRGKDSLYICSILALDPATGKIVWHYQTSPGDPYDYDATNELVLGELPVNGAAR
KVLMQANRNGYFYVLDRSNGKLLSATQFAQKVNWASGIDMKTGRPIDTEMTKAVRSNVESKDFIEAWPSAFGAKNWMPMS
FDPLKKRVYLNTLNFGMKVKYGTPAYRQGAWYLGLELGGWVDPDGGMRGALVAWDPTTGRKLWESPTAAPYWSGVLSTAG
GLVFTGAQTGEFMAFDADTGTKLWQFQTGSGISGLPITWELKGQQYVTVTSGAATVYGFLGGDAKLAQVPAGSSVWTFRL
ID

Specific function: Catalyzes the oxidation of primary alcohols except for methanol that is a very poor substrate [H]

COG id: COG4993

COG function: function code G; Glucose dehydrogenase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial PQQ dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1786316, Length=637, Percent_Identity=24.0188383045526, Blast_Score=129, Evalue=5e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019556
- InterPro:   IPR019551
- InterPro:   IPR018391
- InterPro:   IPR017512
- InterPro:   IPR002372
- InterPro:   IPR011047
- InterPro:   IPR001479 [H]

Pfam domain/function: PF01011 PQQ; PF10535 PQQ_C; PF10527 PQQ_N [H]

EC number: =1.1.2.8 [H]

Molecular weight: Translated: 60859; Mature: 60859

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRDFARAVLGVALACLAPLALAQTIDDLKRDATTPGDVTTYGMGWGQQRYSALAKINKT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHH
TVKRLVPAWNLSLDNSANASTQPLLIGGVMYVSTHNATVAIDAESGRQKWKVAIDLPADV
HHHHHCCEECEECCCCCCCCCCCEEEEEEEEEEECCEEEEEECCCCCCEEEEEEECCCCC
NGYLCCGIQSRGMAALDGVLYRTTIDAHVLAIDMASGKTLWKQKAADYKQGYSMTHAPLV
CCEEEECCCCCCCHHHCCEEEEEEECEEEEEEEECCCCHHHHHHHHHHHHCCCCCCCCEE
AGGVLITGISGGEYGTRGFLDGWDLKTGEKKWRTWTVPAPGEPGSETWNADRHDKGGAPT
ECCEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCE
WLTGTYDPELNLVYWGTGNGGPWNPAWRGKDSLYICSILALDPATGKIVWHYQTSPGDPY
EEEECCCCCEEEEEEECCCCCCCCCCCCCCCCEEEEEEEEECCCCCEEEEEEECCCCCCC
DYDATNELVLGELPVNGAARKVLMQANRNGYFYVLDRSNGKLLSATQFAQKVNWASGIDM
CCCCCCCEEEEECCCCHHHHHHHEEECCCCEEEEEECCCCCEEHHHHHHHHCCCCCCCCC
KTGRPIDTEMTKAVRSNVESKDFIEAWPSAFGAKNWMPMSFDPLKKRVYLNTLNFGMKVK
CCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHEEEEEEECCCEEEE
YGTPAYRQGAWYLGLELGGWVDPDGGMRGALVAWDPTTGRKLWESPTAAPYWSGVLSTAG
ECCCCHHCCCEEEEEEECCEECCCCCCCEEEEEECCCCCCHHHCCCCCCHHHHHHHHHCC
GLVFTGAQTGEFMAFDADTGTKLWQFQTGSGISGLPITWELKGQQYVTVTSGAATVYGFL
CEEEECCCCCCEEEEECCCCCEEEEEECCCCCCCCEEEEEECCCEEEEEECCCEEEEEEE
GGDAKLAQVPAGSSVWTFRLID
CCCCEEEECCCCCCEEEEEEEC
>Mature Secondary Structure
MKRDFARAVLGVALACLAPLALAQTIDDLKRDATTPGDVTTYGMGWGQQRYSALAKINKT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHH
TVKRLVPAWNLSLDNSANASTQPLLIGGVMYVSTHNATVAIDAESGRQKWKVAIDLPADV
HHHHHCCEECEECCCCCCCCCCCEEEEEEEEEEECCEEEEEECCCCCCEEEEEEECCCCC
NGYLCCGIQSRGMAALDGVLYRTTIDAHVLAIDMASGKTLWKQKAADYKQGYSMTHAPLV
CCEEEECCCCCCCHHHCCEEEEEEECEEEEEEEECCCCHHHHHHHHHHHHCCCCCCCCEE
AGGVLITGISGGEYGTRGFLDGWDLKTGEKKWRTWTVPAPGEPGSETWNADRHDKGGAPT
ECCEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCE
WLTGTYDPELNLVYWGTGNGGPWNPAWRGKDSLYICSILALDPATGKIVWHYQTSPGDPY
EEEECCCCCEEEEEEECCCCCCCCCCCCCCCCEEEEEEEEECCCCCEEEEEEECCCCCCC
DYDATNELVLGELPVNGAARKVLMQANRNGYFYVLDRSNGKLLSATQFAQKVNWASGIDM
CCCCCCCEEEEECCCCHHHHHHHEEECCCCEEEEEECCCCCEEHHHHHHHHCCCCCCCCC
KTGRPIDTEMTKAVRSNVESKDFIEAWPSAFGAKNWMPMSFDPLKKRVYLNTLNFGMKVK
CCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHEEEEEEECCCEEEE
YGTPAYRQGAWYLGLELGGWVDPDGGMRGALVAWDPTTGRKLWESPTAAPYWSGVLSTAG
ECCCCHHCCCEEEEEEECCEECCCCCCCEEEEEECCCCCCHHHCCCCCCHHHHHHHHHCC
GLVFTGAQTGEFMAFDADTGTKLWQFQTGSGISGLPITWELKGQQYVTVTSGAATVYGFL
CEEEECCCCCCEEEEECCCCCEEEEEECCCCCCCCEEEEEECCCEEEEEECCCEEEEEEE
GGDAKLAQVPAGSSVWTFRLID
CCCCEEEECCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9826187; 10984043; 10075429; 10736230 [H]