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The map label for this gene is ycgM [C]

Identifier: 124265527

GI number: 124265527

Start: 364293

End: 365138

Strand: Direct

Name: ycgM [C]

Synonym: Mpe_A0334

Alternate gene names: 124265527

Gene position: 364293-365138 (Clockwise)

Preceding gene: 124265521

Following gene: 124265532

Centisome position: 9.01

GC content: 69.15

Gene sequence:

>846_bases
ATGAAACTGATTCGTTACGGTATGCCGGGGCGCGAGAAGCCGGGCCTGGTGGATGCCCACGGCGTGCTGCGCGACCTGTC
CGGCGTGACGCCGCACCTCGACCTGCCGAGCCTCGGACTGGCGGGCCTGCAGCGCTTGCGCCGGATCAAACCCGAGAGCC
TGCCGCGCGTGCGCGGCACGCCGCGCCTGGGTGTGCCGTTCACCGGCATCAGCAAGCTGGTCGCGATCGGCCTGAACTAC
AGCGACCATGCTGCCGAGTCCGGCATGCGGGTGCCGACCGAGCCGATCGTCTTCATGAAGGCGACCACCTGCATCACCGG
CCCCAACGACCCCATCGAGCTGCCGCCGGGATCCCTGAAGACTGACTGGGAGGTTGAGCTGGGCGTCGTGATCGGAAAGA
CCGCCAAGCGCGTGTCCGAGGCCCAGGCGCTGGACCACGTGGCCGGCTACTGCGTGGTGAACGACGTGAGCGAGCGCCAT
TGGCAGGCCGAGCGCGGTGGCACCTGGGACAAAGGCAAGGGCTTCGACAGTTTCGGTCCGATCGGCCCCTGGCTCGTGAC
GCGCGACGAGGTCCCCGACCCGCAGGTGCTGTCGATGTGGCTGGACGTCAACGGCGCGTCGCGCCAGCGCGGCAACACCG
CGACGATGGTGTTCAGCGTGGCGCGGATCATCAGCTATGTCAGCGAATGCATGACGCTGCTGCCCGGCGACGTGATCGCC
ACCGGCACGCCGCCCGGGGTGGGCCTGGGCATGAAGCCGGTGCCGCAGTTCCTGAAGGTCGGCGACGTGGTGAGCCTGGG
CATCGAGGGCCTGGGCGCACAGCGCCAGGTGGTCGTCCCCGGGTGA

Upstream 100 bases:

>100_bases
CGTGGTCATCGGCTTCAGCGTGCTCATTGGTGATGAACTCCTGACGCTATGCTCGACGCAAATTTACCCAGAATGCGGCG
GTGCCGCATCACCCTTGCCA

Downstream 100 bases:

>100_bases
GCAGGGCGATCCGGGCGACGCCGCACCCGACGTGAAAAAGGGCGCCCGCAGGCGCCCTCGTTCGAGAAGTGGAAGCCGGA
CTCAGGCCGCCAGCTTGAAC

Product: 5-carboxymethyl-2-hydroxymuconate delta-isomerase

Products: NA

Alternate protein names: UGL; Ureidoglycolase; Ureidoglycolatase; Ureidoglycolate hydrolase [H]

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MKLIRYGMPGREKPGLVDAHGVLRDLSGVTPHLDLPSLGLAGLQRLRRIKPESLPRVRGTPRLGVPFTGISKLVAIGLNY
SDHAAESGMRVPTEPIVFMKATTCITGPNDPIELPPGSLKTDWEVELGVVIGKTAKRVSEAQALDHVAGYCVVNDVSERH
WQAERGGTWDKGKGFDSFGPIGPWLVTRDEVPDPQVLSMWLDVNGASRQRGNTATMVFSVARIISYVSECMTLLPGDVIA
TGTPPGVGLGMKPVPQFLKVGDVVSLGIEGLGAQRQVVVPG

Sequences:

>Translated_281_residues
MKLIRYGMPGREKPGLVDAHGVLRDLSGVTPHLDLPSLGLAGLQRLRRIKPESLPRVRGTPRLGVPFTGISKLVAIGLNY
SDHAAESGMRVPTEPIVFMKATTCITGPNDPIELPPGSLKTDWEVELGVVIGKTAKRVSEAQALDHVAGYCVVNDVSERH
WQAERGGTWDKGKGFDSFGPIGPWLVTRDEVPDPQVLSMWLDVNGASRQRGNTATMVFSVARIISYVSECMTLLPGDVIA
TGTPPGVGLGMKPVPQFLKVGDVVSLGIEGLGAQRQVVVPG
>Mature_281_residues
MKLIRYGMPGREKPGLVDAHGVLRDLSGVTPHLDLPSLGLAGLQRLRRIKPESLPRVRGTPRLGVPFTGISKLVAIGLNY
SDHAAESGMRVPTEPIVFMKATTCITGPNDPIELPPGSLKTDWEVELGVVIGKTAKRVSEAQALDHVAGYCVVNDVSERH
WQAERGGTWDKGKGFDSFGPIGPWLVTRDEVPDPQVLSMWLDVNGASRQRGNTATMVFSVARIISYVSECMTLLPGDVIA
TGTPPGVGLGMKPVPQFLKVGDVVSLGIEGLGAQRQVVVPG

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=236, Percent_Identity=49.1525423728814, Blast_Score=209, Evalue=2e-54,
Organism=Homo sapiens, GI40786394, Length=236, Percent_Identity=47.8813559322034, Blast_Score=201, Evalue=5e-52,
Organism=Homo sapiens, GI66348062, Length=203, Percent_Identity=41.3793103448276, Blast_Score=149, Evalue=3e-36,
Organism=Homo sapiens, GI215422413, Length=212, Percent_Identity=40.0943396226415, Blast_Score=149, Evalue=3e-36,
Organism=Homo sapiens, GI13654274, Length=203, Percent_Identity=41.3793103448276, Blast_Score=148, Evalue=5e-36,
Organism=Escherichia coli, GI1787428, Length=182, Percent_Identity=37.9120879120879, Blast_Score=130, Evalue=9e-32,
Organism=Caenorhabditis elegans, GI17557057, Length=201, Percent_Identity=37.3134328358209, Blast_Score=142, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6324161, Length=218, Percent_Identity=30.2752293577982, Blast_Score=96, Evalue=8e-21,
Organism=Drosophila melanogaster, GI28572127, Length=271, Percent_Identity=41.3284132841328, Blast_Score=193, Evalue=1e-49,
Organism=Drosophila melanogaster, GI24663695, Length=218, Percent_Identity=38.0733944954128, Blast_Score=145, Evalue=3e-35,
Organism=Drosophila melanogaster, GI28571789, Length=204, Percent_Identity=41.6666666666667, Blast_Score=144, Evalue=4e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: =4.3.2.3 [H]

Molecular weight: Translated: 30054; Mature: 30054

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLIRYGMPGREKPGLVDAHGVLRDLSGVTPHLDLPSLGLAGLQRLRRIKPESLPRVRGT
CCEEECCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCC
PRLGVPFTGISKLVAIGLNYSDHAAESGMRVPTEPIVFMKATTCITGPNDPIELPPGSLK
CCCCCCHHHHHHHHHHCCCCCHHHHHCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCCC
TDWEVELGVVIGKTAKRVSEAQALDHVAGYCVVNDVSERHWQAERGGTWDKGKGFDSFGP
CCCEEEEEEEECHHHHHHHHHHHHHHHHCEEEEECHHHHHHHHHCCCCCCCCCCCCCCCC
IGPWLVTRDEVPDPQVLSMWLDVNGASRQRGNTATMVFSVARIISYVSECMTLLPGDVIA
CCCEEEECCCCCCHHHEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEE
TGTPPGVGLGMKPVPQFLKVGDVVSLGIEGLGAQRQVVVPG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEECCC
>Mature Secondary Structure
MKLIRYGMPGREKPGLVDAHGVLRDLSGVTPHLDLPSLGLAGLQRLRRIKPESLPRVRGT
CCEEECCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCC
PRLGVPFTGISKLVAIGLNYSDHAAESGMRVPTEPIVFMKATTCITGPNDPIELPPGSLK
CCCCCCHHHHHHHHHHCCCCCHHHHHCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCCC
TDWEVELGVVIGKTAKRVSEAQALDHVAGYCVVNDVSERHWQAERGGTWDKGKGFDSFGP
CCCEEEEEEEECHHHHHHHHHHHHHHHHCEEEEECHHHHHHHHHCCCCCCCCCCCCCCCC
IGPWLVTRDEVPDPQVLSMWLDVNGASRQRGNTATMVFSVARIISYVSECMTLLPGDVIA
CCCEEEECCCCCCHHHEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEE
TGTPPGVGLGMKPVPQFLKVGDVVSLGIEGLGAQRQVVVPG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA