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The map label for this gene is kup

Identifier: 124265367

GI number: 124265367

Start: 188104

End: 189990

Strand: Direct

Name: kup

Synonym: Mpe_A0174

Alternate gene names: 124265367

Gene position: 188104-189990 (Clockwise)

Preceding gene: 124265366

Following gene: 124265369

Centisome position: 4.65

GC content: 65.77

Gene sequence:

>1887_bases
GTGCACTCTCGATCCTCCGATCCACCGACCGGCTCCAAGCTGGCGGCCCTGACCCTCGGCGCCGTCGGCGTCGTTTACGG
CGACATCGGGACCAGTCCGCTGTATGCGTTGAAGGAGGTCTTCGCGCACGGGCGCATCGACATCACGCCGGACAACATCT
ACGGCATCCTGTCGCTGGTGGTGTGGACGCTGACGGTCATCGTCTCGCTCAAGTACGTGCTGCTGATCCTGCGCGCCGAC
AACAACGGCGAAGGCGGCCTGATCGCGATGCTGGCGCTGGCCTCCACGGCCGTGAAGGAGCGGCCCGTGCTGCGCCGGAG
ATTGCTGATCCTCGGTGTGTTCGGCACGGCGATCTTCTTCGGCGATGGCGTGATCACGCCCGCCATCTCGGTGCTGTCGG
CGGTGGAAGGTCTGGAGGTCGCCGCGCCCGGGCTGCACCGCTACGTGGTGCCGGTGACGCTGGTGGTCCTGACGCTGCTG
TTCGCCGCGCAGCGCTTCGGCACCGGCGGCATCGGCAAGTTCTTCGGGCCTGTGACGGCCGTGTGGTTCATCGTGCTGGC
GCTGCTCGGCGTGGTGCACATCGTCGAGAACCCGGCGGTGCTGGCCGCGCTGAGCCCGCACTACGCTCTCGCCTTCATGT
GGCAGCACCCCGGCACGGCCTTCGTGTCGCTCGGCGCGGTGGTGCTGTGTGTGACCGGGGCCGAGGCCTTGTATGCAGAC
ATGGGTCACTTCGGCAAGCGGCCGATCCGCCTCGCGTGGTTCAGCCTCGTGATGCCGGCGCTGATGATCAACTACTTCGG
CCAGGGCGCGATGCTGCTGCAGCGGCCGGAGACGGTGAAGAATCCGTTCTACGAGATGGCCCCCGAGTGGGCGCTCTACC
CTCTGATCGTGCTGGCCACGCTGGCGACGGTGATCGCCTCGCAGGCGCTGATCACGGCCGCGTTCTCGGTCACCAAACAG
GCGATCCAGCTCGGCTACTTCCCGCGCCTGCGGGTCACCCACACCTCGGTCAAGGAGACCGGACAGATCTACGTGCCGTT
CGTGAACTGGGGGCTTTACGCCTGCATCGTGCTGGCGGTCGTGACTTTCGGCTCCAGCAGCAAGCTGGCCTCGGCCTACG
GCATCGCGGTGACCACCGACATGCTGATCACCACGACGATGACCTTCTTCGTGATCCGCTACAGCTGGAAATACCCATGG
GCGCTGTGCGTCGCTGCGACCGGCTTCTTCTTTCTGGTCGATGCGATGTTCTTCGCGGCCAACGCGATCAAGATCCTCGA
CGGGGGCTGGTTCCCGCTGGCCATCGGGGCGGCGATGTTCACGCTGATGATGACCTGGAAACAGGGGCGCCGGCTGATGA
GCGAGCGCCTGCGCGAGGAGGCGATCGACCTGAAGAGCTTCCTGGAGTCGGTGTTCATCAGCCCGCCGACGCGGGTTCAG
GGCACGGCGGTGTTCCTGGCGGCCGAGCAGGGCAGCACGCCGAACGCGCTGCTGCACAACCTCAAGCACAACAAGGTGCT
GCACGAGCAGAACCTGTTCGTCACCGTCAGGCACCACGAGGTGCCGTGGATCCCGTTCAGCAAGCGCTGCGAGATCGAGT
CGCTGGGCCACTGCTGCTGGCAGGTGACGCTGAATTTCGGCTTCAAGAACGAACCCGATGTGCCCGAGGCGCTGGCGCTG
CTGCGGGGCCGTGGCGTGCAGCTCGACGACATGGAGACCAGCTATTTCCTGTCGCGCGACATCGTCATTCCGACCATCGG
CAAGGGCATGGCCATCTGGCGCGAGAAGCTGTTCTGCAGCATGCACCGCAACGCGGCGGCGGCGGCTGACTTCCTGAACC
TGCCGACCAACCGCGTCGTGGAGCTGGGCTCGAAGGTCGAGATCTGA

Upstream 100 bases:

>100_bases
GCCGAGGCGGCATCGCGTTGCTGCGCTGCAACAACCCAAAGCGGATCCGCCCTGGGACGCAGCGCAGAATGGGGGCCCTC
GCCGACCCCGCGCCCATTTC

Downstream 100 bases:

>100_bases
GCGGGCCGCGTTACTGCAGCCGCGTCGGCGCGCCGACCAGCTGCACCACCACCAGCCGCACGTTCTTCTGCAGCGCCGAG
ATCGCCTGCCGGTCGCCCGA

Product: potassium uptake protein

Products: K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 628; Mature: 628

Protein sequence:

>628_residues
MHSRSSDPPTGSKLAALTLGAVGVVYGDIGTSPLYALKEVFAHGRIDITPDNIYGILSLVVWTLTVIVSLKYVLLILRAD
NNGEGGLIAMLALASTAVKERPVLRRRLLILGVFGTAIFFGDGVITPAISVLSAVEGLEVAAPGLHRYVVPVTLVVLTLL
FAAQRFGTGGIGKFFGPVTAVWFIVLALLGVVHIVENPAVLAALSPHYALAFMWQHPGTAFVSLGAVVLCVTGAEALYAD
MGHFGKRPIRLAWFSLVMPALMINYFGQGAMLLQRPETVKNPFYEMAPEWALYPLIVLATLATVIASQALITAAFSVTKQ
AIQLGYFPRLRVTHTSVKETGQIYVPFVNWGLYACIVLAVVTFGSSSKLASAYGIAVTTDMLITTTMTFFVIRYSWKYPW
ALCVAATGFFFLVDAMFFAANAIKILDGGWFPLAIGAAMFTLMMTWKQGRRLMSERLREEAIDLKSFLESVFISPPTRVQ
GTAVFLAAEQGSTPNALLHNLKHNKVLHEQNLFVTVRHHEVPWIPFSKRCEIESLGHCCWQVTLNFGFKNEPDVPEALAL
LRGRGVQLDDMETSYFLSRDIVIPTIGKGMAIWREKLFCSMHRNAAAAADFLNLPTNRVVELGSKVEI

Sequences:

>Translated_628_residues
MHSRSSDPPTGSKLAALTLGAVGVVYGDIGTSPLYALKEVFAHGRIDITPDNIYGILSLVVWTLTVIVSLKYVLLILRAD
NNGEGGLIAMLALASTAVKERPVLRRRLLILGVFGTAIFFGDGVITPAISVLSAVEGLEVAAPGLHRYVVPVTLVVLTLL
FAAQRFGTGGIGKFFGPVTAVWFIVLALLGVVHIVENPAVLAALSPHYALAFMWQHPGTAFVSLGAVVLCVTGAEALYAD
MGHFGKRPIRLAWFSLVMPALMINYFGQGAMLLQRPETVKNPFYEMAPEWALYPLIVLATLATVIASQALITAAFSVTKQ
AIQLGYFPRLRVTHTSVKETGQIYVPFVNWGLYACIVLAVVTFGSSSKLASAYGIAVTTDMLITTTMTFFVIRYSWKYPW
ALCVAATGFFFLVDAMFFAANAIKILDGGWFPLAIGAAMFTLMMTWKQGRRLMSERLREEAIDLKSFLESVFISPPTRVQ
GTAVFLAAEQGSTPNALLHNLKHNKVLHEQNLFVTVRHHEVPWIPFSKRCEIESLGHCCWQVTLNFGFKNEPDVPEALAL
LRGRGVQLDDMETSYFLSRDIVIPTIGKGMAIWREKLFCSMHRNAAAAADFLNLPTNRVVELGSKVEI
>Mature_628_residues
MHSRSSDPPTGSKLAALTLGAVGVVYGDIGTSPLYALKEVFAHGRIDITPDNIYGILSLVVWTLTVIVSLKYVLLILRAD
NNGEGGLIAMLALASTAVKERPVLRRRLLILGVFGTAIFFGDGVITPAISVLSAVEGLEVAAPGLHRYVVPVTLVVLTLL
FAAQRFGTGGIGKFFGPVTAVWFIVLALLGVVHIVENPAVLAALSPHYALAFMWQHPGTAFVSLGAVVLCVTGAEALYAD
MGHFGKRPIRLAWFSLVMPALMINYFGQGAMLLQRPETVKNPFYEMAPEWALYPLIVLATLATVIASQALITAAFSVTKQ
AIQLGYFPRLRVTHTSVKETGQIYVPFVNWGLYACIVLAVVTFGSSSKLASAYGIAVTTDMLITTTMTFFVIRYSWKYPW
ALCVAATGFFFLVDAMFFAANAIKILDGGWFPLAIGAAMFTLMMTWKQGRRLMSERLREEAIDLKSFLESVFISPPTRVQ
GTAVFLAAEQGSTPNALLHNLKHNKVLHEQNLFVTVRHHEVPWIPFSKRCEIESLGHCCWQVTLNFGFKNEPDVPEALAL
LRGRGVQLDDMETSYFLSRDIVIPTIGKGMAIWREKLFCSMHRNAAAAADFLNLPTNRVVELGSKVEI

Specific function: Transport of potassium into the cell

COG id: COG3158

COG function: function code P; K+ transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAK/KUP transporter (TC 2.A.72) family

Homologues:

Organism=Escherichia coli, GI48994960, Length=621, Percent_Identity=47.5040257648953, Blast_Score=588, Evalue=1e-169,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KUP_METPP (A2SC47)

Other databases:

- EMBL:   CP000555
- RefSeq:   YP_001019371.1
- STRING:   A2SC47
- GeneID:   4784137
- GenomeReviews:   CP000555_GR
- KEGG:   mpt:Mpe_A0174
- NMPDR:   fig|279263.3.peg.278
- eggNOG:   COG3158
- HOGENOM:   HBG351154
- OMA:   FVIRYSW
- PhylomeDB:   A2SC47
- ProtClustDB:   CLSK951078
- BioCyc:   MPET420662:MPE_A0174-MONOMER
- HAMAP:   MF_01522
- InterPro:   IPR003855
- InterPro:   IPR023051

Pfam domain/function: PF02705 K_trans

EC number: NA

Molecular weight: Translated: 68689; Mature: 68689

Theoretical pI: Translated: 8.92; Mature: 8.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x21535124)-; HASH(0x236de530)-; HASH(0x238a6a34)-; HASH(0x245c0048)-; HASH(0x2400af84)-; HASH(0x23ed47cc)-; HASH(0x24775e04)-; HASH(0x2342a350)-; HASH(0x234ac95c)-; HASH(0x236f3588)-; HASH(0x242c7af0)-;

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHSRSSDPPTGSKLAALTLGAVGVVYGDIGTSPLYALKEVFAHGRIDITPDNIYGILSLV
CCCCCCCCCCCCHHHHHHHHHHHHEECCCCCCHHHHHHHHHHCCCEEECCHHHHHHHHHH
VWTLTVIVSLKYVLLILRADNNGEGGLIAMLALASTAVKERPVLRRRLLILGVFGTAIFF
HHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GDGVITPAISVLSAVEGLEVAAPGLHRYVVPVTLVVLTLLFAAQRFGTGGIGKFFGPVTA
CCCHHHHHHHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
VWFIVLALLGVVHIVENPAVLAALSPHYALAFMWQHPGTAFVSLGAVVLCVTGAEALYAD
HHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEEEECCCHHHHHHHHHHHEECCHHHHHHH
MGHFGKRPIRLAWFSLVMPALMINYFGQGAMLLQRPETVKNPFYEMAPEWALYPLIVLAT
HHHCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHCCHHHHCCCHHHHHHHHHHH
LATVIASQALITAAFSVTKQAIQLGYFPRLRVTHTSVKETGQIYVPFVNWGLYACIVLAV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHCCCCEEEEEHHHHHHHHHHHHH
VTFGSSSKLASAYGIAVTTDMLITTTMTFFVIRYSWKYPWALCVAATGFFFLVDAMFFAA
HHCCCCCCHHHHHCHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHH
NAIKILDGGWFPLAIGAAMFTLMMTWKQGRRLMSERLREEAIDLKSFLESVFISPPTRVQ
CHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GTAVFLAAEQGSTPNALLHNLKHNKVLHEQNLFVTVRHHEVPWIPFSKRCEIESLGHCCW
CEEEEEEECCCCCHHHHHHHHHHCCEEECCCCEEEEEECCCCCCCCCCCCCHHHHCCEEE
QVTLNFGFKNEPDVPEALALLRGRGVQLDDMETSYFLSRDIVIPTIGKGMAIWREKLFCS
EEEEECCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHCCCEEEECCCCHHHHHHHHHHHH
MHRNAAAAADFLNLPTNRVVELGSKVEI
HHCCHHHHHHHHCCCHHHHHHCCCCCCH
>Mature Secondary Structure
MHSRSSDPPTGSKLAALTLGAVGVVYGDIGTSPLYALKEVFAHGRIDITPDNIYGILSLV
CCCCCCCCCCCCHHHHHHHHHHHHEECCCCCCHHHHHHHHHHCCCEEECCHHHHHHHHHH
VWTLTVIVSLKYVLLILRADNNGEGGLIAMLALASTAVKERPVLRRRLLILGVFGTAIFF
HHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GDGVITPAISVLSAVEGLEVAAPGLHRYVVPVTLVVLTLLFAAQRFGTGGIGKFFGPVTA
CCCHHHHHHHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
VWFIVLALLGVVHIVENPAVLAALSPHYALAFMWQHPGTAFVSLGAVVLCVTGAEALYAD
HHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEEEECCCHHHHHHHHHHHEECCHHHHHHH
MGHFGKRPIRLAWFSLVMPALMINYFGQGAMLLQRPETVKNPFYEMAPEWALYPLIVLAT
HHHCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHCCHHHHCCCHHHHHHHHHHH
LATVIASQALITAAFSVTKQAIQLGYFPRLRVTHTSVKETGQIYVPFVNWGLYACIVLAV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHCCCCEEEEEHHHHHHHHHHHHH
VTFGSSSKLASAYGIAVTTDMLITTTMTFFVIRYSWKYPWALCVAATGFFFLVDAMFFAA
HHCCCCCCHHHHHCHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHH
NAIKILDGGWFPLAIGAAMFTLMMTWKQGRRLMSERLREEAIDLKSFLESVFISPPTRVQ
CHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GTAVFLAAEQGSTPNALLHNLKHNKVLHEQNLFVTVRHHEVPWIPFSKRCEIESLGHCCW
CEEEEEEECCCCCHHHHHHHHHHCCEEECCCCEEEEEECCCCCCCCCCCCCHHHHCCEEE
QVTLNFGFKNEPDVPEALALLRGRGVQLDDMETSYFLSRDIVIPTIGKGMAIWREKLFCS
EEEEECCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHCCCEEEECCCCHHHHHHHHHHHH
MHRNAAAAADFLNLPTNRVVELGSKVEI
HHCCHHHHHHHHCCCHHHHHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: K (I) [Periplasm] [C]

Specific reaction: K (I) [Periplasm] = K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA