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The map label for this gene is argC

Identifier: 124025698

GI number: 124025698

Start: 910235

End: 911314

Strand: Direct

Name: argC

Synonym: NATL1_09911

Alternate gene names: 124025698

Gene position: 910235-911314 (Clockwise)

Preceding gene: 124025696

Following gene: 124025700

Centisome position: 48.81

GC content: 35.0

Gene sequence:

>1080_bases
ATGGCAAAAAGTACATCGAAAACTGGGAGGATCGCAATTATTGGAGCATCTGGATACGGTGGACTTCAACTAGTCAAGTT
GATCAATGAGCATCCTAATTTCGAGATTTCAACCCTAAATGGTGAGCGATCAGTGGGTAAAAACTGGAATGAAATAAATC
CTTTTATGAAAATTTTGCAAGATAAAAAGATTACTAAAAGCAATATTGACGAAATCGCTCTTGATTCTGATTATGCAATA
TTAAGTCTTCCTAATGGCTTATCATCACAGTTAACACCTTTATTGTTAAAAAAAGGTGTTAAGGTCCTCGATTTGTCGGC
TGATTATAGATTTAAATCTCTTGATAAATGGAAAGAAGTCTATACAAAAGAGGCAGCGAAATATAAAAGATATGACTACG
AATTATGTGAAGAGGCTATTTATGGTTTTTCAGAAGAATTTAGTAGCGAAATCTCAAAGTCAAGATTAATTGCCTGTCCA
GGTTGCTATCCAACTGCCTCACTTAGTTTACTTATTCCATTTTTAAAACAAGGTTTAATAGAAAGTGAGGGGATTATTGT
TGATGCAAAATCTGGTACATCTGGTGGTGGGAGAAATCCAAATGAGCAACTATTATTGTCTGAATGCTCTGAATCAATTA
GCCCCTATGGAGTTATTGGACATAGGCACACGGCTGAAATAGAAAGGATTGCCAGTCATTTTGCTGGTCACGAAGTCAAT
TTACAATTCACTCCTCATTTAGTGCCAATGGTTAGAGGGATTTTGTCGACAGTTTACGCTCGTTTAAGAGATCCCGGATT
AACAGCTGAAGACTGCAAAATTGTAATTGAAGCTTTTTATAAAGATCAACCATTTATTGATATCCTGCCTGTAGGAATAT
ATCCAGCAACTAAATGGGTTAAAAATACTAATAAAGTTATGATTTCTGTTGAAGTAGATAAACGTAACGGAAGAATTGTT
CTAATGAGTGTTATAGATAATCTTCTAAAAGGTCAAGCAGGACAGGCAGTCCAAAATTTAAATATTATGCACGGACTTGA
ATCAGATATTGGTCTTCCTAAGATTACTTTTTATCCTTGA

Upstream 100 bases:

>100_bases
CTTCTGATTTCAACTTATTCCTCGTGTTTGTGGTGAAATGGTTCTTTGCTAATTATTCTCAAATGAATATCTCCTCATTC
TACGAAATAACATTGATGTT

Downstream 100 bases:

>100_bases
AACTAGTTCTAATTTCAATTGCTACTTTAGCAATCGCTAAAGGTAATATTATATGTTCCATATCTTGAATTCTTTTTTTT
AAGGTTTCTATACTATCTTT

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase

Number of amino acids: Translated: 359; Mature: 358

Protein sequence:

>359_residues
MAKSTSKTGRIAIIGASGYGGLQLVKLINEHPNFEISTLNGERSVGKNWNEINPFMKILQDKKITKSNIDEIALDSDYAI
LSLPNGLSSQLTPLLLKKGVKVLDLSADYRFKSLDKWKEVYTKEAAKYKRYDYELCEEAIYGFSEEFSSEISKSRLIACP
GCYPTASLSLLIPFLKQGLIESEGIIVDAKSGTSGGGRNPNEQLLLSECSESISPYGVIGHRHTAEIERIASHFAGHEVN
LQFTPHLVPMVRGILSTVYARLRDPGLTAEDCKIVIEAFYKDQPFIDILPVGIYPATKWVKNTNKVMISVEVDKRNGRIV
LMSVIDNLLKGQAGQAVQNLNIMHGLESDIGLPKITFYP

Sequences:

>Translated_359_residues
MAKSTSKTGRIAIIGASGYGGLQLVKLINEHPNFEISTLNGERSVGKNWNEINPFMKILQDKKITKSNIDEIALDSDYAI
LSLPNGLSSQLTPLLLKKGVKVLDLSADYRFKSLDKWKEVYTKEAAKYKRYDYELCEEAIYGFSEEFSSEISKSRLIACP
GCYPTASLSLLIPFLKQGLIESEGIIVDAKSGTSGGGRNPNEQLLLSECSESISPYGVIGHRHTAEIERIASHFAGHEVN
LQFTPHLVPMVRGILSTVYARLRDPGLTAEDCKIVIEAFYKDQPFIDILPVGIYPATKWVKNTNKVMISVEVDKRNGRIV
LMSVIDNLLKGQAGQAVQNLNIMHGLESDIGLPKITFYP
>Mature_358_residues
AKSTSKTGRIAIIGASGYGGLQLVKLINEHPNFEISTLNGERSVGKNWNEINPFMKILQDKKITKSNIDEIALDSDYAIL
SLPNGLSSQLTPLLLKKGVKVLDLSADYRFKSLDKWKEVYTKEAAKYKRYDYELCEEAIYGFSEEFSSEISKSRLIACPG
CYPTASLSLLIPFLKQGLIESEGIIVDAKSGTSGGGRNPNEQLLLSECSESISPYGVIGHRHTAEIERIASHFAGHEVNL
QFTPHLVPMVRGILSTVYARLRDPGLTAEDCKIVIEAFYKDQPFIDILPVGIYPATKWVKNTNKVMISVEVDKRNGRIVL
MSVIDNLLKGQAGQAVQNLNIMHGLESDIGLPKITFYP

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=338, Percent_Identity=33.7278106508876, Blast_Score=162, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6320913, Length=352, Percent_Identity=28.6931818181818, Blast_Score=118, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC_PROM1 (A2C239)

Other databases:

- EMBL:   CP000553
- RefSeq:   YP_001014814.1
- ProteinModelPortal:   A2C239
- SMR:   A2C239
- STRING:   A2C239
- GeneID:   4780017
- GenomeReviews:   CP000553_GR
- KEGG:   pme:NATL1_09911
- eggNOG:   COG0002
- HOGENOM:   HBG294213
- OMA:   VCRIAVH
- ProtClustDB:   PRK00436
- BioCyc:   PMAR167555:NATL1_09911-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00150
- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01850

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC

EC number: =1.2.1.38

Molecular weight: Translated: 39740; Mature: 39609

Theoretical pI: Translated: 7.53; Mature: 7.53

Prosite motif: PS01224 ARGC

Important sites: ACT_SITE 162-162

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKSTSKTGRIAIIGASGYGGLQLVKLINEHPNFEISTLNGERSVGKNWNEINPFMKILQ
CCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHH
DKKITKSNIDEIALDSDYAILSLPNGLSSQLTPLLLKKGVKVLDLSADYRFKSLDKWKEV
CCCCCCCCCCCEEECCCEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHH
YTKEAAKYKRYDYELCEEAIYGFSEEFSSEISKSRLIACPGCYPTASLSLLIPFLKQGLI
HHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHCCEEECCCCCCHHHHHHHHHHHHHCCC
ESEGIIVDAKSGTSGGGRNPNEQLLLSECSESISPYGVIGHRHTAEIERIASHFAGHEVN
CCCCEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHCCCEEE
LQFTPHLVPMVRGILSTVYARLRDPGLTAEDCKIVIEAFYKDQPFIDILPVGIYPATKWV
EEECCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHH
KNTNKVMISVEVDKRNGRIVLMSVIDNLLKGQAGQAVQNLNIMHGLESDIGLPKITFYP
CCCCEEEEEEEEECCCCCEEEHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCEEEECC
>Mature Secondary Structure 
AKSTSKTGRIAIIGASGYGGLQLVKLINEHPNFEISTLNGERSVGKNWNEINPFMKILQ
CCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHH
DKKITKSNIDEIALDSDYAILSLPNGLSSQLTPLLLKKGVKVLDLSADYRFKSLDKWKEV
CCCCCCCCCCCEEECCCEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHH
YTKEAAKYKRYDYELCEEAIYGFSEEFSSEISKSRLIACPGCYPTASLSLLIPFLKQGLI
HHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHCCEEECCCCCCHHHHHHHHHHHHHCCC
ESEGIIVDAKSGTSGGGRNPNEQLLLSECSESISPYGVIGHRHTAEIERIASHFAGHEVN
CCCCEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHCCCEEE
LQFTPHLVPMVRGILSTVYARLRDPGLTAEDCKIVIEAFYKDQPFIDILPVGIYPATKWV
EEECCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHH
KNTNKVMISVEVDKRNGRIVLMSVIDNLLKGQAGQAVQNLNIMHGLESDIGLPKITFYP
CCCCEEEEEEEEECCCCCEEEHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA