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The map label for this gene is 124025527

Identifier: 124025527

GI number: 124025527

Start: 754079

End: 755146

Strand: Reverse

Name: 124025527

Synonym: NATL1_08201

Alternate gene names: NA

Gene position: 755146-754079 (Counterclockwise)

Preceding gene: 124025528

Following gene: 124025521

Centisome position: 40.5

GC content: 41.57

Gene sequence:

>1068_bases
ATGGCACTCTCGTACTACGCAGAAGAACTAAAGAAGACCGCAAGTGCCATAGCCCAGCCAGGCAAAGGGATTCTTGCTGT
TGACGAGTCAACGAAAACAGTAGGTAAAAGGCTTGCTTCAATAGGTGTTGAGAACACTGAGGACAACAGAAAAGCATATA
GAGGTATGCTTTTCACCACAGAAGGTCTTGGAAACTTCATAAGCGGAGCGATTCTTTTTGAAGAAACTCTTTTCCAGAAC
CATCCAGATGGTGAGCCAATGGTTAAAAAGCTTGAGAAGCTAGGCATAATTCCAGGAATCAAAGTTGACAAAGGTCTAAG
ACCATTAGCCGGTGGACATGATGTAGAAACTTTTTGTTCAGGTTTAGACGGTCTTGTTGAAAGAGCTGCTGATTATTACG
AGCAAGGTGCAAGATTTGCCAAGTGGAGAGCAGTACTTCAAATAACAGACGATGGTTGTCCTTCTAAACTTTCTATTAGA
GAAAATGCTTGGGGTTTAGCAAGATACGCTAGATCAGTTCAAGAATCTGGCTTGGTTCCAATTATTGAACCAGAAATCTT
AATGGATGGTTCACATTCAATTGAAAAGACAGCAGCAGTTCAAGAAGAAGTAATTAAAGAAGTTTACTTAGCTTGCCAGG
TAAATGGAGTACTTCTAGAGGGAACTCTTCTGAAGCCATCAATGACTGTTCAAGGTGCTGACAGCTCAACAAAAGCTGAT
CCTCAGCAAGTAGCTGAAATGACAATCCGTACAATGGAACGCTGTGTACCTGCAAGTGTCCCTGGTATTACTTTCCTTTC
AGGTGGATTGAGCGAGGAAGCTGCATCAGTTTATCTAAATCTGATGAATAAGATCGACAGAAAGGCTAAGTGGAATGTTT
CATTCTCATATGGTCGTGCTTTACAACATTCATGTCTAAAAGCATGGAAAGGCTCGAACACTTCTGATGGACAAAAAGCA
CTCATAGCTAGAGCTCAGGCAAACTCTGAGGCATCAAAAGGATTGTATGTTGCTGGTTCTCAGCCTTCTTCTGATGAGCA
ATTATTTGTAGCTGGATACAAGTACTAA

Upstream 100 bases:

>100_bases
TTAATTATTGGATTAAAAAAATAAAAAACTTTTTAGGTGTAATAAGCAACAAAAGGGGCCTTTGATATGGAATAATCTTA
ATGAAATTTTTGTTGCATAA

Downstream 100 bases:

>100_bases
TCTAAAAAAGCTAACAAAAAGCTGCTATCTCTCATTTTGATAGCAGCTTTTTTAATGCCTTGATTTATAAATTCAAGAAA
GAAGTGTACTAAGAATTGAC

Product: fructose-1,6-bisphosphate aldolase

Products: NA

Alternate protein names: Fructose-biphosphate aldolase class I; FBP aldolase [H]

Number of amino acids: Translated: 355; Mature: 354

Protein sequence:

>355_residues
MALSYYAEELKKTASAIAQPGKGILAVDESTKTVGKRLASIGVENTEDNRKAYRGMLFTTEGLGNFISGAILFEETLFQN
HPDGEPMVKKLEKLGIIPGIKVDKGLRPLAGGHDVETFCSGLDGLVERAADYYEQGARFAKWRAVLQITDDGCPSKLSIR
ENAWGLARYARSVQESGLVPIIEPEILMDGSHSIEKTAAVQEEVIKEVYLACQVNGVLLEGTLLKPSMTVQGADSSTKAD
PQQVAEMTIRTMERCVPASVPGITFLSGGLSEEAASVYLNLMNKIDRKAKWNVSFSYGRALQHSCLKAWKGSNTSDGQKA
LIARAQANSEASKGLYVAGSQPSSDEQLFVAGYKY

Sequences:

>Translated_355_residues
MALSYYAEELKKTASAIAQPGKGILAVDESTKTVGKRLASIGVENTEDNRKAYRGMLFTTEGLGNFISGAILFEETLFQN
HPDGEPMVKKLEKLGIIPGIKVDKGLRPLAGGHDVETFCSGLDGLVERAADYYEQGARFAKWRAVLQITDDGCPSKLSIR
ENAWGLARYARSVQESGLVPIIEPEILMDGSHSIEKTAAVQEEVIKEVYLACQVNGVLLEGTLLKPSMTVQGADSSTKAD
PQQVAEMTIRTMERCVPASVPGITFLSGGLSEEAASVYLNLMNKIDRKAKWNVSFSYGRALQHSCLKAWKGSNTSDGQKA
LIARAQANSEASKGLYVAGSQPSSDEQLFVAGYKY
>Mature_354_residues
ALSYYAEELKKTASAIAQPGKGILAVDESTKTVGKRLASIGVENTEDNRKAYRGMLFTTEGLGNFISGAILFEETLFQNH
PDGEPMVKKLEKLGIIPGIKVDKGLRPLAGGHDVETFCSGLDGLVERAADYYEQGARFAKWRAVLQITDDGCPSKLSIRE
NAWGLARYARSVQESGLVPIIEPEILMDGSHSIEKTAAVQEEVIKEVYLACQVNGVLLEGTLLKPSMTVQGADSSTKADP
QQVAEMTIRTMERCVPASVPGITFLSGGLSEEAASVYLNLMNKIDRKAKWNVSFSYGRALQHSCLKAWKGSNTSDGQKAL
IARAQANSEASKGLYVAGSQPSSDEQLFVAGYKY

Specific function: Unknown

COG id: COG3588

COG function: function code G; Fructose-1,6-bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class I fructose-bisphosphate aldolase family [H]

Homologues:

Organism=Homo sapiens, GI40354205, Length=353, Percent_Identity=49.2917847025496, Blast_Score=317, Evalue=1e-86,
Organism=Homo sapiens, GI34577112, Length=353, Percent_Identity=49.0084985835694, Blast_Score=307, Evalue=8e-84,
Organism=Homo sapiens, GI34577110, Length=353, Percent_Identity=49.0084985835694, Blast_Score=307, Evalue=8e-84,
Organism=Homo sapiens, GI4557305, Length=353, Percent_Identity=49.0084985835694, Blast_Score=307, Evalue=8e-84,
Organism=Homo sapiens, GI193794814, Length=353, Percent_Identity=49.0084985835694, Blast_Score=307, Evalue=8e-84,
Organism=Homo sapiens, GI4885063, Length=353, Percent_Identity=47.3087818696884, Blast_Score=306, Evalue=1e-83,
Organism=Caenorhabditis elegans, GI25150450, Length=354, Percent_Identity=47.4576271186441, Blast_Score=307, Evalue=5e-84,
Organism=Caenorhabditis elegans, GI71983985, Length=351, Percent_Identity=49.2877492877493, Blast_Score=304, Evalue=4e-83,
Organism=Caenorhabditis elegans, GI71983990, Length=232, Percent_Identity=51.7241379310345, Blast_Score=214, Evalue=4e-56,
Organism=Drosophila melanogaster, GI45553577, Length=353, Percent_Identity=51.8413597733711, Blast_Score=331, Evalue=5e-91,
Organism=Drosophila melanogaster, GI24650282, Length=351, Percent_Identity=51.2820512820513, Blast_Score=321, Evalue=4e-88,
Organism=Drosophila melanogaster, GI24650280, Length=351, Percent_Identity=51.2820512820513, Blast_Score=321, Evalue=4e-88,
Organism=Drosophila melanogaster, GI24650278, Length=351, Percent_Identity=51.2820512820513, Blast_Score=321, Evalue=4e-88,
Organism=Drosophila melanogaster, GI221459619, Length=353, Percent_Identity=50.4249291784703, Blast_Score=316, Evalue=1e-86,
Organism=Drosophila melanogaster, GI24650288, Length=353, Percent_Identity=50.4249291784703, Blast_Score=316, Evalue=1e-86,
Organism=Drosophila melanogaster, GI24650304, Length=340, Percent_Identity=46.1764705882353, Blast_Score=280, Evalue=1e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000741
- InterPro:   IPR013785 [H]

Pfam domain/function: PF00274 Glycolytic [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 38409; Mature: 38278

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS00158 ALDOLASE_CLASS_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALSYYAEELKKTASAIAQPGKGILAVDESTKTVGKRLASIGVENTEDNRKAYRGMLFTT
CCHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHCCCCCCCHHHHHHHCEEEEE
EGLGNFISGAILFEETLFQNHPDGEPMVKKLEKLGIIPGIKVDKGLRPLAGGHDVETFCS
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHH
GLDGLVERAADYYEQGARFAKWRAVLQITDDGCPSKLSIRENAWGLARYARSVQESGLVP
HHHHHHHHHHHHHHHCCHHHHHEEEEEEECCCCCCCCEEHHHHHHHHHHHHHHHHCCCCE
IIEPEILMDGSHSIEKTAAVQEEVIKEVYLACQVNGVLLEGTLLKPSMTVQGADSSTKAD
EECCCEEECCCCCHHHHHHHHHHHHHHHHHHHEECCEEEECEEECCCCEEECCCCCCCCC
PQQVAEMTIRTMERCVPASVPGITFLSGGLSEEAASVYLNLMNKIDRKAKWNVSFSYGRA
HHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHCCCCEECEEHHHHHH
LQHSCLKAWKGSNTSDGQKALIARAQANSEASKGLYVAGSQPSSDEQLFVAGYKY
HHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCEEEECCCCCCCCEEEEEECCC
>Mature Secondary Structure 
ALSYYAEELKKTASAIAQPGKGILAVDESTKTVGKRLASIGVENTEDNRKAYRGMLFTT
CHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHCCCCCCCHHHHHHHCEEEEE
EGLGNFISGAILFEETLFQNHPDGEPMVKKLEKLGIIPGIKVDKGLRPLAGGHDVETFCS
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHH
GLDGLVERAADYYEQGARFAKWRAVLQITDDGCPSKLSIRENAWGLARYARSVQESGLVP
HHHHHHHHHHHHHHHCCHHHHHEEEEEEECCCCCCCCEEHHHHHHHHHHHHHHHHCCCCE
IIEPEILMDGSHSIEKTAAVQEEVIKEVYLACQVNGVLLEGTLLKPSMTVQGADSSTKAD
EECCCEEECCCCCHHHHHHHHHHHHHHHHHHHEECCEEEECEEECCCCEEECCCCCCCCC
PQQVAEMTIRTMERCVPASVPGITFLSGGLSEEAASVYLNLMNKIDRKAKWNVSFSYGRA
HHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHCCCCEECEEHHHHHH
LQHSCLKAWKGSNTSDGQKALIARAQANSEASKGLYVAGSQPSSDEQLFVAGYKY
HHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCEEEECCCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]