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The map label for this gene is upp [H]

Identifier: 124025521

GI number: 124025521

Start: 750390

End: 751007

Strand: Reverse

Name: upp [H]

Synonym: NATL1_08141

Alternate gene names: 124025521

Gene position: 751007-750390 (Counterclockwise)

Preceding gene: 124025527

Following gene: 124025520

Centisome position: 40.27

GC content: 35.44

Gene sequence:

>618_bases
ATGTCAATGAGCTTAAGAGTAATAGTTCCTCCACACCCACTCATATCACATTGGTTAACTATTTTAAGGAACCCTACTAC
CCCAGAAATCCTTTATGCAACGGGCCTAGAGCAACTTGGCACCTGGCTCACTTATGAAGCGCTTAGAGATTGGATCCCAA
GTAAAAAAGAGCAGATTACAACTTCAACTGGAACAACTGAATGCTCAGTCATTGATCCCAATATACCTATTTTAGCAATT
CCTTATTTACCCGCTGGGCTTGAGCTCTATAGAGGTGCGAGAAATTTAATTCCAAATTCAAATTTGTGTATCGGAGGTCT
ACCTAAAGAAATTGAAGAAAATGCTGGAATTATTTTTTACATCGACCAAATAACAACAGGTAAAAATCTTTTAAAAGATT
TAAATTATTTAAAAGATAAAGAAATTGATTCAAGAAGGATAAGGGTAATCACAGCATTAGCCTCTAATCAAGGACTTAAA
GAAATAGGAGAATATATTCAAGATTTGAATATTTATTGTGCTTGTATAGATCCTGAATTAATATCAGAAAGTGAATTATC
GCCTGGAATTGGTGATCCATCATTACGTATCAAAACCAGAGTCACCTCATCGCACTAG

Upstream 100 bases:

>100_bases
TCCGAGATGAAAGAAGTTTTTTTGTTCATAGGAGCTTAAAAGGACTTTTAACAGGTAATTTACTTATTCACGTTATGGCA
CATAAGGCCAAGAATGAATC

Downstream 100 bases:

>100_bases
CATTTAACGAAGTTATTAAAAGTTATGAGCCAATACAGAGATTCAAATTCAGGAAGTTTGGCATCATTAATTAGTGGTGC
CGTACTTGGAGCTGCAGGTT

Product: putative uracil phosphoribosyltransferase

Products: NA

Alternate protein names: UMP pyrophosphorylase; UPRTase [H]

Number of amino acids: Translated: 205; Mature: 204

Protein sequence:

>205_residues
MSMSLRVIVPPHPLISHWLTILRNPTTPEILYATGLEQLGTWLTYEALRDWIPSKKEQITTSTGTTECSVIDPNIPILAI
PYLPAGLELYRGARNLIPNSNLCIGGLPKEIEENAGIIFYIDQITTGKNLLKDLNYLKDKEIDSRRIRVITALASNQGLK
EIGEYIQDLNIYCACIDPELISESELSPGIGDPSLRIKTRVTSSH

Sequences:

>Translated_205_residues
MSMSLRVIVPPHPLISHWLTILRNPTTPEILYATGLEQLGTWLTYEALRDWIPSKKEQITTSTGTTECSVIDPNIPILAI
PYLPAGLELYRGARNLIPNSNLCIGGLPKEIEENAGIIFYIDQITTGKNLLKDLNYLKDKEIDSRRIRVITALASNQGLK
EIGEYIQDLNIYCACIDPELISESELSPGIGDPSLRIKTRVTSSH
>Mature_204_residues
SMSLRVIVPPHPLISHWLTILRNPTTPEILYATGLEQLGTWLTYEALRDWIPSKKEQITTSTGTTECSVIDPNIPILAIP
YLPAGLELYRGARNLIPNSNLCIGGLPKEIEENAGIIFYIDQITTGKNLLKDLNYLKDKEIDSRRIRVITALASNQGLKE
IGEYIQDLNIYCACIDPELISESELSPGIGDPSLRIKTRVTSSH

Specific function: Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate [H]

COG id: COG0035

COG function: function code F; Uracil phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPRTase family [H]

Homologues:

None

Paralogues:

None

Copy number: 2580 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836
- InterPro:   IPR005765 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.9 [H]

Molecular weight: Translated: 22841; Mature: 22709

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMSLRVIVPPHPLISHWLTILRNPTTPEILYATGLEQLGTWLTYEALRDWIPSKKEQIT
CCCEEEEEECCCHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHCCCCHHEEE
TSTGTTECSVIDPNIPILAIPYLPAGLELYRGARNLIPNSNLCIGGLPKEIEENAGIIFY
ECCCCCEEEEECCCCCEEEECCCCCCHHHHHHHHHCCCCCCEEECCCCHHHHCCCCEEEE
IDQITTGKNLLKDLNYLKDKEIDSRRIRVITALASNQGLKEIGEYIQDLNIYCACIDPEL
EECCCCHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCHHHHHHHHHCCCEEEEEECHHH
ISESELSPGIGDPSLRIKTRVTSSH
HCCCCCCCCCCCCCEEEEEEECCCC
>Mature Secondary Structure 
SMSLRVIVPPHPLISHWLTILRNPTTPEILYATGLEQLGTWLTYEALRDWIPSKKEQIT
CCEEEEEECCCHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHCCCCHHEEE
TSTGTTECSVIDPNIPILAIPYLPAGLELYRGARNLIPNSNLCIGGLPKEIEENAGIIFY
ECCCCCEEEEECCCCCEEEECCCCCCHHHHHHHHHCCCCCCEEECCCCHHHHCCCCEEEE
IDQITTGKNLLKDLNYLKDKEIDSRRIRVITALASNQGLKEIGEYIQDLNIYCACIDPEL
EECCCCHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCHHHHHHHHHCCCEEEEEECHHH
ISESELSPGIGDPSLRIKTRVTSSH
HCCCCCCCCCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]