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The map label for this gene is cumB [H]

Identifier: 124025482

GI number: 124025482

Start: 707933

End: 708400

Strand: Reverse

Name: cumB [H]

Synonym: NATL1_07751

Alternate gene names: 124025482

Gene position: 708400-707933 (Counterclockwise)

Preceding gene: 124025484

Following gene: 124025480

Centisome position: 37.99

GC content: 39.1

Gene sequence:

>468_bases
ATGACGAGATTGCTAACGAAAGCAAGACTTGTAGGCGAAAGAGGGGAGGTTCCTATTGCTGCAGTTATTCTCGACAAAAA
AGGTAGGTGTATTGGCTATGGGGGGAACAGGAGAGAATCAATGAAAGATCCTTTAGGTCATGCTGAGTTAGTAGCGCTTC
GCCAAGCTTCTTGGATTAAAAATGATTGGAGATTTAATGACTGTACATTGATAGTAAATCTAGAGCCATGTCCCATGTGC
GCAGGGGCATTAATACAAGCAAGAATGGGTAAGATTATCTATGGATCTGAAGATCCAAAGAGAGGCGCGCTAGGTGGAAC
TATTAATCTAGCGGAACATAAAAGTGCACATCACAGACTGTTGATTGAAAAAGGAATCATGGAAGAAGAATCTAAGAAGA
TTATAGTGGATTGGTTTAAAGATAAAAGATTAATAGCCAGAGAAAATTTGTTATCTAAACTTAGGTAA

Upstream 100 bases:

>100_bases
ATGATTAATCTCTAGATAAACATTTTATTTGATAGTTCACCAAACATCTAAAAAATTGTCAAAACCAATCGATCTGAATC
AGAAAGAAAAAATAAAGTGG

Downstream 100 bases:

>100_bases
TTCAGTTTCAAAAATATTTATTATCTTATCTACATTTTCAGAGGTGGAGTTATATCCCATTAAACCAATTCTCCATACTT
TTCCAGCCAGATCACCTAAT

Product: putative cytidine/deoxycytidylate deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 155; Mature: 154

Protein sequence:

>155_residues
MTRLLTKARLVGERGEVPIAAVILDKKGRCIGYGGNRRESMKDPLGHAELVALRQASWIKNDWRFNDCTLIVNLEPCPMC
AGALIQARMGKIIYGSEDPKRGALGGTINLAEHKSAHHRLLIEKGIMEEESKKIIVDWFKDKRLIARENLLSKLR

Sequences:

>Translated_155_residues
MTRLLTKARLVGERGEVPIAAVILDKKGRCIGYGGNRRESMKDPLGHAELVALRQASWIKNDWRFNDCTLIVNLEPCPMC
AGALIQARMGKIIYGSEDPKRGALGGTINLAEHKSAHHRLLIEKGIMEEESKKIIVDWFKDKRLIARENLLSKLR
>Mature_154_residues
TRLLTKARLVGERGEVPIAAVILDKKGRCIGYGGNRRESMKDPLGHAELVALRQASWIKNDWRFNDCTLIVNLEPCPMCA
GALIQARMGKIIYGSEDPKRGALGGTINLAEHKSAHHRLLIEKGIMEEESKKIIVDWFKDKRLIARENLLSKLR

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Escherichia coli, GI145693172, Length=143, Percent_Identity=39.8601398601399, Blast_Score=117, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17541138, Length=129, Percent_Identity=33.3333333333333, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 17443; Mature: 17312

Theoretical pI: Translated: 10.22; Mature: 10.22

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRLLTKARLVGERGEVPIAAVILDKKGRCIGYGGNRRESMKDPLGHAELVALRQASWIK
CCCHHHHHHHCCCCCCCCEEEEEECCCCCEEECCCCCCCHHHCCCCHHHHHHHHHHHHHC
NDWRFNDCTLIVNLEPCPMCAGALIQARMGKIIYGSEDPKRGALGGTINLAEHKSAHHRL
CCCEECCEEEEEECCCCCCHHHHHHHHHCCEEEECCCCCCCCCCCCEEEHHHCCCCHHHH
LIEKGIMEEESKKIIVDWFKDKRLIARENLLSKLR
HHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
TRLLTKARLVGERGEVPIAAVILDKKGRCIGYGGNRRESMKDPLGHAELVALRQASWIK
CCHHHHHHHCCCCCCCCEEEEEECCCCCEEECCCCCCCHHHCCCCHHHHHHHHHHHHHC
NDWRFNDCTLIVNLEPCPMCAGALIQARMGKIIYGSEDPKRGALGGTINLAEHKSAHHRL
CCCEECCEEEEEECCCCCCHHHHHHHHHCCEEEECCCCCCCCCCCCEEEHHHCCCCHHHH
LIEKGIMEEESKKIIVDWFKDKRLIARENLLSKLR
HHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]