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The map label for this gene is pncA [C]

Identifier: 124025408

GI number: 124025408

Start: 642230

End: 642841

Strand: Reverse

Name: pncA [C]

Synonym: NATL1_06991

Alternate gene names: 124025408

Gene position: 642841-642230 (Counterclockwise)

Preceding gene: 124025410

Following gene: 124025407

Centisome position: 34.47

GC content: 27.12

Gene sequence:

>612_bases
ATGGATCAATTCATAAAAACAAATCCAAACCCAATCAATACAAATAATAATAATAATAAAATAATAGTAGAGGACGAAAC
ATTACTACTTATCGTAGATGTGCAGCAAAAGCTTATCAAGAATATAAAAGACAATCAACAATTATTATTTAACATAAAAA
AGCTGACTGATACCTGCAATTTGCTTAATGTTCGTGTCGCTATTACGGAACAAAATCCATTGAAACTTGGGAAGACTCTA
GAATCTATTACAGATAATAATGAATATCCTAAATTTGAAAAAATGGAATTTAGTTGTATTTACAATAAGAACTTTATTAA
GTATATAAATGATTATAATTTTAAGAATATTATAGTTAGTGGGATTGAGAGTCATATATGTGTTCTTCAAACATCGATGG
ATCTTTTACAAAAAGGATTAAACATTTTAATCCCAAGAGATGCTATTGGAAGTAGAAATGAAATGGACAATGATACAGCT
TTTTTAAGGCTTATATTATCTGGTGCAGTTGCATCCACGACTGAAAGTCTAATATGTGAATTATGTAAGACCTCTAATAG
AAAAGAATTTAGGGAAGTAAGTAAAATTTTAAAAAACTCATTTTCAAATTAA

Upstream 100 bases:

>100_bases
CCGCAACAAAAGGGAAGGCTTTTTCAGATTCTTTTCGATAAAAATCATGTTTAAATTTATTAGATGATTTATATTTAGAT
AAACAGAAAGAAATTCTAAG

Downstream 100 bases:

>100_bases
ATAATTAGAAAATATCTAGACAAATCAATTTTTTCAGGCAATCTGAAGAAAAGTAATCTGACATCATGGACGATTTTTAT
AAAAACATAATCATTTCATT

Product: isochorismatase hydrolase family protein

Products: NA

Alternate protein names: Isochorismatase Family Protein; Isochorismatase Hydrolase Family Protein; Isochorismatase Superfamily Hydrolase; Nicotinamidase-Like Amidase; Amidase; Isochorismatase Family Hydrolase; Isochorismatase Domain-Containing; Hydrolase; Amidohydrolase; Hydrolase Isochorismatase; Amidase Related Nicotinamidase; YcaC Like Amidohydrolase; Isochorismatase Family; Isochorismatase; Nicotinamidase; YcaC-Related Amidohydrolase; Isochorismatase Domain-Containing A; Isochorismatase Hydrolase Family; Hydrolase Isochorismatase Family; Nicotinamidase-Related Amidase

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MDQFIKTNPNPINTNNNNNKIIVEDETLLLIVDVQQKLIKNIKDNQQLLFNIKKLTDTCNLLNVRVAITEQNPLKLGKTL
ESITDNNEYPKFEKMEFSCIYNKNFIKYINDYNFKNIIVSGIESHICVLQTSMDLLQKGLNILIPRDAIGSRNEMDNDTA
FLRLILSGAVASTTESLICELCKTSNRKEFREVSKILKNSFSN

Sequences:

>Translated_203_residues
MDQFIKTNPNPINTNNNNNKIIVEDETLLLIVDVQQKLIKNIKDNQQLLFNIKKLTDTCNLLNVRVAITEQNPLKLGKTL
ESITDNNEYPKFEKMEFSCIYNKNFIKYINDYNFKNIIVSGIESHICVLQTSMDLLQKGLNILIPRDAIGSRNEMDNDTA
FLRLILSGAVASTTESLICELCKTSNRKEFREVSKILKNSFSN
>Mature_203_residues
MDQFIKTNPNPINTNNNNNKIIVEDETLLLIVDVQQKLIKNIKDNQQLLFNIKKLTDTCNLLNVRVAITEQNPLKLGKTL
ESITDNNEYPKFEKMEFSCIYNKNFIKYINDYNFKNIIVSGIESHICVLQTSMDLLQKGLNILIPRDAIGSRNEMDNDTA
FLRLILSGAVASTTESLICELCKTSNRKEFREVSKILKNSFSN

Specific function: Unknown

COG id: COG1335

COG function: function code Q; Amidases related to nicotinamidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI209969695, Length=178, Percent_Identity=29.7752808988764, Blast_Score=91, Evalue=5e-19,
Organism=Homo sapiens, GI103471987, Length=174, Percent_Identity=25.8620689655172, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI13376007, Length=194, Percent_Identity=27.319587628866, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17540156, Length=176, Percent_Identity=34.6590909090909, Blast_Score=112, Evalue=2e-25,
Organism=Drosophila melanogaster, GI19922924, Length=174, Percent_Identity=34.4827586206897, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI21357489, Length=179, Percent_Identity=30.1675977653631, Blast_Score=84, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 23266; Mature: 23266

Theoretical pI: Translated: 7.82; Mature: 7.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQFIKTNPNPINTNNNNNKIIVEDETLLLIVDVQQKLIKNIKDNQQLLFNIKKLTDTCN
CCCCCCCCCCCCCCCCCCCEEEEECCEEEEEEEHHHHHHHHCCCCHHHHHHHHHHHHHHC
LLNVRVAITEQNPLKLGKTLESITDNNEYPKFEKMEFSCIYNKNFIKYINDYNFKNIIVS
EEEEEEEEECCCCHHHHHHHHHHHCCCCCCCHHCEEEEEEECCCHHHHHCCCCHHHHHHH
GIESHICVLQTSMDLLQKGLNILIPRDAIGSRNEMDNDTAFLRLILSGAVASTTESLICE
HHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LCKTSNRKEFREVSKILKNSFSN
HHHCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDQFIKTNPNPINTNNNNNKIIVEDETLLLIVDVQQKLIKNIKDNQQLLFNIKKLTDTCN
CCCCCCCCCCCCCCCCCCCEEEEECCEEEEEEEHHHHHHHHCCCCHHHHHHHHHHHHHHC
LLNVRVAITEQNPLKLGKTLESITDNNEYPKFEKMEFSCIYNKNFIKYINDYNFKNIIVS
EEEEEEEEECCCCHHHHHHHHHHHCCCCCCCHHCEEEEEEECCCHHHHHCCCCHHHHHHH
GIESHICVLQTSMDLLQKGLNILIPRDAIGSRNEMDNDTAFLRLILSGAVASTTESLICE
HHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LCKTSNRKEFREVSKILKNSFSN
HHHCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA