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The map label for this gene is murI

Identifier: 124025384

GI number: 124025384

Start: 621848

End: 622645

Strand: Direct

Name: murI

Synonym: NATL1_06751

Alternate gene names: 124025384

Gene position: 621848-622645 (Clockwise)

Preceding gene: 124025383

Following gene: 124025385

Centisome position: 33.35

GC content: 32.58

Gene sequence:

>798_bases
ATGCGTATTGGATTATTTGATAGTGGTATTGGAGGCTTCACTGTTCTAAAAAAGGTTATTGAGTTATGTCCCAATAATTC
ATTTATATATTTAGCTGATACAGCAAGACTTCCTTATGGAGTAAAGACAAATAATGAGATCAAAAAAATTGCTGAAGAAA
TATCATCTTGGTTTAGATATCAAAATATTGACGCTTTTTTGGTTGCCTGTAACACAACAAATGCCATTGCCTTGGACGTA
ATTAAAAACAATTTAGATATCCCTGTCTTTGACCTTATTGGCTCTGCTGCCTCAAACATTCAGGAATCTAGGGTGGGTGT
TCTCGCAACTCCTTCTACAGTAAGAACAAAAGCTTATACAAATGCGATTTTAGAATTCAAGCCAAAAACTTTTGTAATTG
AGCAACCATGCCCTGCATTTGTTCCAATGATTGAAATGGATAATATTAATTCAGATGATATTACTGACGTTGCGACTGGG
TATTTACAACCTCTTTTAAAACAAAAAATTCATTCTTTAATTCTTGGTTGTAGTCATTATCCTCTCATCACTTCCTCTCT
GAGAAAGGTTTTACCATCAAGTGTTAAATTGATTGACCCTGCAGAAGCTCTTTCTTTTAAATTAAAGTTTTTTATTGATT
CAAAAACAAGAAATTATTCAAAGAATAAAAATTTTGTTGATTTAAAGTTTTACGTAACCTCTAACCTGAAAAATTTTTCC
AATAAAGCAAAGCATTGGTTAGATGTATTTCCTGAAGTTAATCTTGTTTCACTGCAGAAGAAGGGCTGGGTCTCTTAA

Upstream 100 bases:

>100_bases
CGTATGACGCCGATTTGTTACGACAAAAAGTTTATAGGGATAAAATGTCTTTTGCTATTGCTAGGGGAATACTTAACTAT
CTAAAAATTTCAAAATAGAT

Downstream 100 bases:

>100_bases
TATCAAAAAGTAGAGCGGTTTTATGACCACAGCCACGGAAATTCTTCAACCTGTAGAACTTGATCTAGAAGCGTTGCTTT
TGGATCTTCGCAGCCTCATA

Product: putative aspartate and glutamate racemases:glutamate racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MRIGLFDSGIGGFTVLKKVIELCPNNSFIYLADTARLPYGVKTNNEIKKIAEEISSWFRYQNIDAFLVACNTTNAIALDV
IKNNLDIPVFDLIGSAASNIQESRVGVLATPSTVRTKAYTNAILEFKPKTFVIEQPCPAFVPMIEMDNINSDDITDVATG
YLQPLLKQKIHSLILGCSHYPLITSSLRKVLPSSVKLIDPAEALSFKLKFFIDSKTRNYSKNKNFVDLKFYVTSNLKNFS
NKAKHWLDVFPEVNLVSLQKKGWVS

Sequences:

>Translated_265_residues
MRIGLFDSGIGGFTVLKKVIELCPNNSFIYLADTARLPYGVKTNNEIKKIAEEISSWFRYQNIDAFLVACNTTNAIALDV
IKNNLDIPVFDLIGSAASNIQESRVGVLATPSTVRTKAYTNAILEFKPKTFVIEQPCPAFVPMIEMDNINSDDITDVATG
YLQPLLKQKIHSLILGCSHYPLITSSLRKVLPSSVKLIDPAEALSFKLKFFIDSKTRNYSKNKNFVDLKFYVTSNLKNFS
NKAKHWLDVFPEVNLVSLQKKGWVS
>Mature_265_residues
MRIGLFDSGIGGFTVLKKVIELCPNNSFIYLADTARLPYGVKTNNEIKKIAEEISSWFRYQNIDAFLVACNTTNAIALDV
IKNNLDIPVFDLIGSAASNIQESRVGVLATPSTVRTKAYTNAILEFKPKTFVIEQPCPAFVPMIEMDNINSDDITDVATG
YLQPLLKQKIHSLILGCSHYPLITSSLRKVLPSSVKLIDPAEALSFKLKFFIDSKTRNYSKNKNFVDLKFYVTSNLKNFS
NKAKHWLDVFPEVNLVSLQKKGWVS

Specific function: Provides the (R)-glutamate required for cell wall biosynthesis

COG id: COG0796

COG function: function code M; Glutamate racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate/glutamate racemases family

Homologues:

Organism=Escherichia coli, GI87082355, Length=219, Percent_Identity=26.9406392694064, Blast_Score=86, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURI_PROM1 (A2C175)

Other databases:

- EMBL:   CP000553
- RefSeq:   YP_001014500.1
- ProteinModelPortal:   A2C175
- SMR:   A2C175
- STRING:   A2C175
- GeneID:   4780837
- GenomeReviews:   CP000553_GR
- KEGG:   pme:NATL1_06751
- eggNOG:   COG0796
- HOGENOM:   HBG645102
- OMA:   CGHIPYG
- ProtClustDB:   CLSK938787
- BioCyc:   PMAR167555:NATL1_06751-MONOMER
- HAMAP:   MF_00258
- InterPro:   IPR015942
- InterPro:   IPR001920
- InterPro:   IPR004391
- Gene3D:   G3DSA:3.40.50.1860
- TIGRFAMs:   TIGR00067

Pfam domain/function: PF01177 Asp_Glu_race; SSF53681 Asp/Glu_race

EC number: =5.1.1.3

Molecular weight: Translated: 29692; Mature: 29692

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: PS00923 ASP_GLU_RACEMASE_1; PS00924 ASP_GLU_RACEMASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIGLFDSGIGGFTVLKKVIELCPNNSFIYLADTARLPYGVKTNNEIKKIAEEISSWFRY
CEEECCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHH
QNIDAFLVACNTTNAIALDVIKNNLDIPVFDLIGSAASNIQESRVGVLATPSTVRTKAYT
CCCCEEEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHH
NAILEFKPKTFVIEQPCPAFVPMIEMDNINSDDITDVATGYLQPLLKQKIHSLILGCSHY
HHHEEECCCEEEEECCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
PLITSSLRKVLPSSVKLIDPAEALSFKLKFFIDSKTRNYSKNKNFVDLKFYVTSNLKNFS
HHHHHHHHHHCCCCCEEECCHHHHEEEEEEEEECCCCCCCCCCCEEEEEEEEECCCHHHH
NKAKHWLDVFPEVNLVSLQKKGWVS
HHHHHHHHHCCCCCEEEECCCCCCC
>Mature Secondary Structure
MRIGLFDSGIGGFTVLKKVIELCPNNSFIYLADTARLPYGVKTNNEIKKIAEEISSWFRY
CEEECCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHH
QNIDAFLVACNTTNAIALDVIKNNLDIPVFDLIGSAASNIQESRVGVLATPSTVRTKAYT
CCCCEEEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHH
NAILEFKPKTFVIEQPCPAFVPMIEMDNINSDDITDVATGYLQPLLKQKIHSLILGCSHY
HHHEEECCCEEEEECCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
PLITSSLRKVLPSSVKLIDPAEALSFKLKFFIDSKTRNYSKNKNFVDLKFYVTSNLKNFS
HHHHHHHHHHCCCCCEEECCHHHHEEEEEEEEECCCCCCCCCCCEEEEEEEEECCCHHHH
NKAKHWLDVFPEVNLVSLQKKGWVS
HHHHHHHHHCCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA