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The map label for this gene is argB

Identifier: 124025268

GI number: 124025268

Start: 505970

End: 506884

Strand: Reverse

Name: argB

Synonym: NATL1_05571

Alternate gene names: 124025268

Gene position: 506884-505970 (Counterclockwise)

Preceding gene: 124025269

Following gene: 124025267

Centisome position: 27.18

GC content: 39.23

Gene sequence:

>915_bases
ATGAATAAAGAAATCCAACAAGCTAACCACAGTAAGAATATTAATAAACCCTTCACAGACAAAGATTCAATAAGGGTTTC
TGTCTTAAGTGAGGCACTTCCTTATATTCAGCGTTTTGCAAATAAGCGAATCGTAATAAAATATGGTGGCTCAGCCATGG
CAGATAAAACACTTCAAAATGCAGTATTTAGAGATCTAGCTCTTCTCTCGTCTGTTGGAGTACAAATAGTAGTCGTTCAT
GGTGGGGGGCCAGAAATAAACCAATGGTTAGAAAAATTAGGAATAAAACCAGTTTTCCTTGATGGTTTACGTATTACTGA
TACCGAGACCATGGATGTCGTAGAAATGGTTCTTACGGGAAGAGTAAATAAACAGATTGTAAGTGGAATAAACAATCACG
GAAGATTGGCTGTTGGACTATGTGGAATAGATGGCGGACTTATTGAGGCAAGAACGCTTGGAGGTGGAAGTCATGGTCTT
GTTGGAGAAGTTGCAAAAGTAAATACAAAGATTTTGAGCCCTCTTCTCGAAGAAGGTTACGTCCCAGTCATTTCTAGCGT
AGCCAACTCTTCTGATGGCAGATCACACAATATCAATGCTGATACTGTTGCTGGGGAGCTTGCTGCAGCACTAGGTGCCG
AAAAATTAATCCTTCTAACAGATACTCCTGGTATTTTAAGAAATGAAAATGATCCTTCTTCCTTAATAGAAAAGATACGT
CTATCGGAAGCTAGAGAATTAATTGATCAAGGGATAGTTAAAGCAGGTATGAAACCAAAAGTTGAATGTTGTATACGTTC
GCTTGCCCAAGGTGTTAATGCTGCCCATATCATTGACGGAAGGACTCCTCACTCACTTCTTTTAGAAGTTTTCACTGATG
CAGGTATTGGAACAATGGTTATGGGTAGAGGTTAA

Upstream 100 bases:

>100_bases
TTCTTTGCTAAAGGTTTGTGCGCTGAATTATTTTGTCCTACACCAGGTGCAATAGATTTAATACTACTTCCGCAAAAACA
AGAAGATAATCCACAAGAAA

Downstream 100 bases:

>100_bases
ATGTCAAATATAGCTTCAGCTATAAAAGCTACTGAAGCGGCCCTTGAAAAAGGTGATTACGGTATTTGCATAAAAATAAT
TGACCCTTTACTTCTAGATT

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MNKEIQQANHSKNINKPFTDKDSIRVSVLSEALPYIQRFANKRIVIKYGGSAMADKTLQNAVFRDLALLSSVGVQIVVVH
GGGPEINQWLEKLGIKPVFLDGLRITDTETMDVVEMVLTGRVNKQIVSGINNHGRLAVGLCGIDGGLIEARTLGGGSHGL
VGEVAKVNTKILSPLLEEGYVPVISSVANSSDGRSHNINADTVAGELAAALGAEKLILLTDTPGILRNENDPSSLIEKIR
LSEARELIDQGIVKAGMKPKVECCIRSLAQGVNAAHIIDGRTPHSLLLEVFTDAGIGTMVMGRG

Sequences:

>Translated_304_residues
MNKEIQQANHSKNINKPFTDKDSIRVSVLSEALPYIQRFANKRIVIKYGGSAMADKTLQNAVFRDLALLSSVGVQIVVVH
GGGPEINQWLEKLGIKPVFLDGLRITDTETMDVVEMVLTGRVNKQIVSGINNHGRLAVGLCGIDGGLIEARTLGGGSHGL
VGEVAKVNTKILSPLLEEGYVPVISSVANSSDGRSHNINADTVAGELAAALGAEKLILLTDTPGILRNENDPSSLIEKIR
LSEARELIDQGIVKAGMKPKVECCIRSLAQGVNAAHIIDGRTPHSLLLEVFTDAGIGTMVMGRG
>Mature_304_residues
MNKEIQQANHSKNINKPFTDKDSIRVSVLSEALPYIQRFANKRIVIKYGGSAMADKTLQNAVFRDLALLSSVGVQIVVVH
GGGPEINQWLEKLGIKPVFLDGLRITDTETMDVVEMVLTGRVNKQIVSGINNHGRLAVGLCGIDGGLIEARTLGGGSHGL
VGEVAKVNTKILSPLLEEGYVPVISSVANSSDGRSHNINADTVAGELAAALGAEKLILLTDTPGILRNENDPSSLIEKIR
LSEARELIDQGIVKAGMKPKVECCIRSLAQGVNAAHIIDGRTPHSLLLEVFTDAGIGTMVMGRG

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family

Homologues:

Organism=Escherichia coli, GI1789181, Length=283, Percent_Identity=25.4416961130742, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI145693208, Length=236, Percent_Identity=33.4745762711864, Blast_Score=90, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6320913, Length=268, Percent_Identity=33.2089552238806, Blast_Score=117, Evalue=3e-27,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ARGB_PROM1 (A2C0V9)

Other databases:

- EMBL:   CP000553
- RefSeq:   YP_001014384.1
- ProteinModelPortal:   A2C0V9
- SMR:   A2C0V9
- STRING:   A2C0V9
- GeneID:   4780293
- GenomeReviews:   CP000553_GR
- KEGG:   pme:NATL1_05571
- eggNOG:   COG0548
- HOGENOM:   HBG497643
- OMA:   MDIVEMV
- ProtClustDB:   PRK00942
- BioCyc:   PMAR167555:NATL1_05571-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00082_B
- InterPro:   IPR004662
- InterPro:   IPR001048
- InterPro:   IPR001057
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF000728
- PRINTS:   PR00474
- TIGRFAMs:   TIGR00761

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: =2.7.2.8

Molecular weight: Translated: 32381; Mature: 32381

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: NA

Important sites: BINDING 104-104 BINDING 197-197

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKEIQQANHSKNINKPFTDKDSIRVSVLSEALPYIQRFANKRIVIKYGGSAMADKTLQN
CCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHH
AVFRDLALLSSVGVQIVVVHGGGPEINQWLEKLGIKPVFLDGLRITDTETMDVVEMVLTG
HHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHCCCEEEECCEEECCCHHHHHHHHHHHC
RVNKQIVSGINNHGRLAVGLCGIDGGLIEARTLGGGSHGLVGEVAKVNTKILSPLLEEGY
CCHHHHHHCCCCCCCEEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCC
VPVISSVANSSDGRSHNINADTVAGELAAALGAEKLILLTDTPGILRNENDPSSLIEKIR
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHH
LSEARELIDQGIVKAGMKPKVECCIRSLAQGVNAAHIIDGRTPHSLLLEVFTDAGIGTMV
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCCCEEE
MGRG
ECCC
>Mature Secondary Structure
MNKEIQQANHSKNINKPFTDKDSIRVSVLSEALPYIQRFANKRIVIKYGGSAMADKTLQN
CCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHH
AVFRDLALLSSVGVQIVVVHGGGPEINQWLEKLGIKPVFLDGLRITDTETMDVVEMVLTG
HHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHCCCEEEECCEEECCCHHHHHHHHHHHC
RVNKQIVSGINNHGRLAVGLCGIDGGLIEARTLGGGSHGLVGEVAKVNTKILSPLLEEGY
CCHHHHHHCCCCCCCEEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCC
VPVISSVANSSDGRSHNINADTVAGELAAALGAEKLILLTDTPGILRNENDPSSLIEKIR
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHH
LSEARELIDQGIVKAGMKPKVECCIRSLAQGVNAAHIIDGRTPHSLLLEVFTDAGIGTMV
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCCCEEE
MGRG
ECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA