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The map label for this gene is yciC [H]

Identifier: 124025258

GI number: 124025258

Start: 495530

End: 496558

Strand: Reverse

Name: yciC [H]

Synonym: NATL1_05471

Alternate gene names: 124025258

Gene position: 496558-495530 (Counterclockwise)

Preceding gene: 124025259

Following gene: 124025257

Centisome position: 26.63

GC content: 30.03

Gene sequence:

>1029_bases
ATGAACACTAACGTATCTAATCTTAATAAAAATATGGCTTCCAAAACAAATATCCCTATTACAATTATATCAGGGTTTTT
AGGCTCAGGTAAAACAACTTTATTAAATCATATACTTACTAATCAGCAAGGTATAAAGACAGCTGTATTAGTTAACGAGT
TTGGCGAAATAGGAATTGATAATGAGTTAATAATTAAGACTGAAGAAGAAATGATAGAACTAAGTAATGGATGCATATGT
TGCTCTATAAATGGTGAGTTAGTAGAAGCAATAGAAAAGTTAATTAATGTCAACAAGAAGTTAGACTACATTATCATTGA
AACTACAGGATTAGCAGATCCTCTTCCAGTTGCGATGACATTACTTGGAAGTGATTTAAGAGATCAAACAAGATTAGACT
CAATTATAACTCTAATTGATGCTGAGAACTTTAATGATGTTGCTTTAGAAAGTTCAATAGGAAGATCACAGGTAATCTAT
GGTGATATTTTACTTCTAAATAAATGTGATTTAGTAACTAATAAAAATATAGAAGAAACAATAGACAAGTTAAAAGAAAT
AAAAAATGATGTGAGAATTTTAAAAAGCATTAAAGGAAATATTCCTCTTAATCTATTATTAAGTGTGGGTCTATTTGAAA
CTGATCTAATTAATCAAAAAGAATCAGTCCATGATCACTCTCATGGACATGGACATGGACATGGACATGGACATGTCCAT
GGACACTCAGAGGAAGATAATAGAATTGAAGATTTTCTTTCTGTTTCTTTTCAAACTAAAGAACCTTTCTCTCTTAGAAA
ATTCCAATATTTTCTAGATAATCAATTAAAAAGCGATGTTTTCAGAGCAAAGGGTATACTTTGGTTCAGCGAAAGCGAAA
GAAGACATGTCTTTCACCTCGCTGGCAAAAGAATTTCTATTGAAGATAGTGAATGGGGAGAAGAAAGAAATAATCAACTT
GTCTTTATTGGTAAAGAATTAGATAAAGAAAAAATACTCTCTCAATTAAATGCATGTATTGACAAATAA

Upstream 100 bases:

>100_bases
ACTCATGATAAAGGTGGAATAACTACCAATGACATAAAGCTTGCTGAGTCTATTGATAAATTAAACAATACCTAATTTAC
CATTATTTACTGCAATTAAA

Downstream 100 bases:

>100_bases
TCACAAAATACCAAATTTAAGAATAAATTGAACAACAACAGACCCGCTTCAAAGGCCTTCAAAATAGAAAAAAATATTAA
TTTTGTTTATAATCTAATTG

Product: G3E family GTPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MNTNVSNLNKNMASKTNIPITIISGFLGSGKTTLLNHILTNQQGIKTAVLVNEFGEIGIDNELIIKTEEEMIELSNGCIC
CSINGELVEAIEKLINVNKKLDYIIIETTGLADPLPVAMTLLGSDLRDQTRLDSIITLIDAENFNDVALESSIGRSQVIY
GDILLLNKCDLVTNKNIEETIDKLKEIKNDVRILKSIKGNIPLNLLLSVGLFETDLINQKESVHDHSHGHGHGHGHGHVH
GHSEEDNRIEDFLSVSFQTKEPFSLRKFQYFLDNQLKSDVFRAKGILWFSESERRHVFHLAGKRISIEDSEWGEERNNQL
VFIGKELDKEKILSQLNACIDK

Sequences:

>Translated_342_residues
MNTNVSNLNKNMASKTNIPITIISGFLGSGKTTLLNHILTNQQGIKTAVLVNEFGEIGIDNELIIKTEEEMIELSNGCIC
CSINGELVEAIEKLINVNKKLDYIIIETTGLADPLPVAMTLLGSDLRDQTRLDSIITLIDAENFNDVALESSIGRSQVIY
GDILLLNKCDLVTNKNIEETIDKLKEIKNDVRILKSIKGNIPLNLLLSVGLFETDLINQKESVHDHSHGHGHGHGHGHVH
GHSEEDNRIEDFLSVSFQTKEPFSLRKFQYFLDNQLKSDVFRAKGILWFSESERRHVFHLAGKRISIEDSEWGEERNNQL
VFIGKELDKEKILSQLNACIDK
>Mature_342_residues
MNTNVSNLNKNMASKTNIPITIISGFLGSGKTTLLNHILTNQQGIKTAVLVNEFGEIGIDNELIIKTEEEMIELSNGCIC
CSINGELVEAIEKLINVNKKLDYIIIETTGLADPLPVAMTLLGSDLRDQTRLDSIITLIDAENFNDVALESSIGRSQVIY
GDILLLNKCDLVTNKNIEETIDKLKEIKNDVRILKSIKGNIPLNLLLSVGLFETDLINQKESVHDHSHGHGHGHGHGHVH
GHSEEDNRIEDFLSVSFQTKEPFSLRKFQYFLDNQLKSDVFRAKGILWFSESERRHVFHLAGKRISIEDSEWGEERNNQL
VFIGKELDKEKILSQLNACIDK

Specific function: May bind GTP. Might act as metal chaperone (Potential). Contributes to optimal growth under starvation for zinc [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI33469141, Length=363, Percent_Identity=30.8539944903581, Blast_Score=142, Evalue=4e-34,
Organism=Homo sapiens, GI126722884, Length=348, Percent_Identity=31.0344827586207, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI146231952, Length=346, Percent_Identity=31.5028901734104, Blast_Score=135, Evalue=7e-32,
Organism=Homo sapiens, GI148727351, Length=346, Percent_Identity=31.2138728323699, Blast_Score=134, Evalue=9e-32,
Organism=Homo sapiens, GI223941779, Length=348, Percent_Identity=31.8965517241379, Blast_Score=132, Evalue=4e-31,
Organism=Homo sapiens, GI223941776, Length=336, Percent_Identity=30.0595238095238, Blast_Score=122, Evalue=3e-28,
Organism=Homo sapiens, GI119120938, Length=131, Percent_Identity=45.8015267175573, Blast_Score=108, Evalue=5e-24,
Organism=Escherichia coli, GI87082430, Length=327, Percent_Identity=31.8042813455657, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1788499, Length=215, Percent_Identity=30.2325581395349, Blast_Score=85, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6324356, Length=262, Percent_Identity=31.2977099236641, Blast_Score=113, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 38392; Mature: 38392

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTNVSNLNKNMASKTNIPITIISGFLGSGKTTLLNHILTNQQGIKTAVLVNEFGEIGID
CCCCHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCEEEHHHHHHHCCCCC
NELIIKTEEEMIELSNGCICCSINGELVEAIEKLINVNKKLDYIIIETTGLADPLPVAMT
CCEEEECHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHH
LLGSDLRDQTRLDSIITLIDAENFNDVALESSIGRSQVIYGDILLLNKCDLVTNKNIEET
HHCCCHHHHHHHHHHHHEEECCCCCCCHHHHCCCCCEEEEEEEEEEECCCCCCCCCHHHH
IDKLKEIKNDVRILKSIKGNIPLNLLLSVGLFETDLINQKESVHDHSHGHGHGHGHGHVH
HHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHCCHHHHCCCCCCCCCCCCCCCCC
GHSEEDNRIEDFLSVSFQTKEPFSLRKFQYFLDNQLKSDVFRAKGILWFSESERRHVFHL
CCCCCCHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCEEEEE
AGKRISIEDSEWGEERNNQLVFIGKELDKEKILSQLNACIDK
CCCEEECCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MNTNVSNLNKNMASKTNIPITIISGFLGSGKTTLLNHILTNQQGIKTAVLVNEFGEIGID
CCCCHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCEEEHHHHHHHCCCCC
NELIIKTEEEMIELSNGCICCSINGELVEAIEKLINVNKKLDYIIIETTGLADPLPVAMT
CCEEEECHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHH
LLGSDLRDQTRLDSIITLIDAENFNDVALESSIGRSQVIYGDILLLNKCDLVTNKNIEET
HHCCCHHHHHHHHHHHHEEECCCCCCCHHHHCCCCCEEEEEEEEEEECCCCCCCCCHHHH
IDKLKEIKNDVRILKSIKGNIPLNLLLSVGLFETDLINQKESVHDHSHGHGHGHGHGHVH
HHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHCCHHHHCCCCCCCCCCCCCCCCC
GHSEEDNRIEDFLSVSFQTKEPFSLRKFQYFLDNQLKSDVFRAKGILWFSESERRHVFHL
CCCCCCHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCEEEEE
AGKRISIEDSEWGEERNNQLVFIGKELDKEKILSQLNACIDK
CCCEEECCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 9811636 [H]