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The map label for this gene is 124025259

Identifier: 124025259

GI number: 124025259

Start: 496584

End: 496889

Strand: Reverse

Name: 124025259

Synonym: NATL1_05481

Alternate gene names: NA

Gene position: 496889-496584 (Counterclockwise)

Preceding gene: 124025260

Following gene: 124025258

Centisome position: 26.65

GC content: 26.14

Gene sequence:

>306_bases
ATGAAATATAAAAAACCCATGGTTTCCTTAATAGAGAAAAATCAACTAGATTCTTTTATAAAAAAGAATCCTTCTTGGAT
AATAGATAATAAAACGATAAAGAAAGAATTTAAATTTCAAAATTTCATTGAGGCTTTTGGCTTTATGAGTAAAGTCGCTA
TTTTAGCTGAAAAAATAGATCATCATCCAGATTGGCAGAATACATATAATAAAGTTAAAATCAATTTAACAACTCATGAT
AAAGGTGGAATAACTACCAATGACATAAAGCTTGCTGAGTCTATTGATAAATTAAACAATACCTAA

Upstream 100 bases:

>100_bases
ATAGGCTTATGGCAAGCCATATATATATGGGAACATAGAACATCAAATAAATCAAGGTCATTACAATTACATGCAATTGG
TGATTTTGATTTAAATTAAA

Downstream 100 bases:

>100_bases
TTTACCATTATTTACTGCAATTAAAATGAACACTAACGTATCTAATCTTAATAAAAATATGGCTTCCAAAACAAATATCC
CTATTACAATTATATCAGGG

Product: 4a-hydroxytetrahydrobiopterin dehydratase (PCD)

Products: NA

Alternate protein names: PHS; 4-alpha-hydroxy-tetrahydropterin dehydratase; Pterin carbinolamine dehydratase; PCD [H]

Number of amino acids: Translated: 101; Mature: 101

Protein sequence:

>101_residues
MKYKKPMVSLIEKNQLDSFIKKNPSWIIDNKTIKKEFKFQNFIEAFGFMSKVAILAEKIDHHPDWQNTYNKVKINLTTHD
KGGITTNDIKLAESIDKLNNT

Sequences:

>Translated_101_residues
MKYKKPMVSLIEKNQLDSFIKKNPSWIIDNKTIKKEFKFQNFIEAFGFMSKVAILAEKIDHHPDWQNTYNKVKINLTTHD
KGGITTNDIKLAESIDKLNNT
>Mature_101_residues
MKYKKPMVSLIEKNQLDSFIKKNPSWIIDNKTIKKEFKFQNFIEAFGFMSKVAILAEKIDHHPDWQNTYNKVKINLTTHD
KGGITTNDIKLAESIDKLNNT

Specific function: Unknown

COG id: COG2154

COG function: function code H; Pterin-4a-carbinolamine dehydratase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pterin-4-alpha-carbinolamine dehydratase family [H]

Homologues:

Organism=Homo sapiens, GI134133240, Length=90, Percent_Identity=52.2222222222222, Blast_Score=92, Evalue=9e-20,
Organism=Homo sapiens, GI4557831, Length=100, Percent_Identity=42, Blast_Score=82, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI115533705, Length=96, Percent_Identity=45.8333333333333, Blast_Score=95, Evalue=7e-21,
Organism=Drosophila melanogaster, GI45549100, Length=102, Percent_Identity=39.2156862745098, Blast_Score=83, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001533 [H]

Pfam domain/function: PF01329 Pterin_4a [H]

EC number: =4.2.1.96 [H]

Molecular weight: Translated: 11785; Mature: 11785

Theoretical pI: Translated: 10.13; Mature: 10.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYKKPMVSLIEKNQLDSFIKKNPSWIIDNKTIKKEFKFQNFIEAFGFMSKVAILAEKID
CCCCHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
HHPDWQNTYNKVKINLTTHDKGGITTNDIKLAESIDKLNNT
CCCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MKYKKPMVSLIEKNQLDSFIKKNPSWIIDNKTIKKEFKFQNFIEAFGFMSKVAILAEKID
CCCCHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
HHPDWQNTYNKVKINLTTHDKGGITTNDIKLAESIDKLNNT
CCCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA