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The map label for this gene is thiP [H]

Identifier: 124025257

GI number: 124025257

Start: 493916

End: 495502

Strand: Reverse

Name: thiP [H]

Synonym: NATL1_05461

Alternate gene names: 124025257

Gene position: 495502-493916 (Counterclockwise)

Preceding gene: 124025258

Following gene: 124025252

Centisome position: 26.57

GC content: 33.96

Gene sequence:

>1587_bases
TTGAACAACAACAGACCCGCTTCAAAGGCCTTCAAAATAGAAAAAAATATTAATTTTGTTTATAATCTAATTGGATTAAA
TAATAGTCGATACATATTAAAGTACTTAGTAGTTTTATTAACATTTTTTATTTTATGGCCGTTATTTAATCTCGTAAAAG
AGGGTTTATACGGTATTCAAAAAGGTTCTATTTATTTAACGACAGCAAATCTTAATGACATAAAAGGAACACTTTTACTA
TTGATTTTTTCTCTAACTCTAGGAGGATTTTTAGGTGTAACAAATGGTTGGATTTTAGCCAATTGCCATTTCAAAGGTAG
AAAAGTTCTTAGAGTTTGCCAACTAATTCCTTTCGCAACTCCAGCTTATCTTTTAGCTGCTACATTCATTGACCTCGGTA
GCATTTATTCCATCAGAATTACCGGCATGTTGTGGGGTGTAGTAATAATGGCATTCACAACATATCCATATGTATTTTTA
CTAAGTTTAGAAAGTTTTGAGGAAGGCGGTAGAAAACAAATTGAAGCATGCAGAACTCTTGGTATAGGTCCTTGGAAAAG
TTTTTTTAGAATATCTCTCCCAATAGCAATTCCCTCAATCACTGCTGGATTAGCTTTAATGGCCATGGAAATCATAAATG
AATTAGGAGCCGTTCAACTTTTAAATATTCCAAGTATTTCAGCTGGAATACTTGAGAGTTGGGTAGAGGAAGGTGAGCCC
TCAGGTGCCATTGCTCTTGCCTTATTTGCTCTGATTTTAGTTTTTCTATTAGTTGCAATAGAACGCAAATCAAGAGAAAA
AAGTAAACGCTGGATAGACGGAATAAGTAGCGTAGATTCACCAAAATGGGAATTAAAAGGTATAAATCTATTCCTTGCTC
AAGTTGTAACCTTTACTCCTCCAATTCTTACATTGGGTATTCCAATCACATGGGCAATAATAAATATTGATCAAATAAAT
CAAGGGTTCAATATAGATTTAATTGGATTGACTATCAGAAGCTTTAGCTTAGCCTTAGCTGTTTCATTAATAACGATATT
TATATCATTGATTTTATCAATTTCCAAGAGGTGGCATAATCATCAATGGCTCAATATATTTACCTTCTTATCCAGTATTG
GCTATGCAATTCCAGGATCTGTTTTAGCCCTTGCTCTTCTTTCCTTTCAAGGAAGTATCTGGCAAGTCAACATATTAAGC
TTACTAATCTGGGGTTATAGCATTCGATTCTTAGCTGTTTCCAAAGGTGGTCTTGATGCTGGATTTGAGAGGATCTCGCC
AAATATAGATAATGCAGCCATAAATCTCGGAAAAAACTGGTCGGAGGTCCTTTTAAAAATACATCTACCACTTCTCAAAG
GACCTATTCTGGTAGGCATCCTTCTTGTTTTTGTTGACACAATAAAGGAATTACCACTAACTTTTATATTAAGACCATTT
GATTTTGATACGCTTTCAGTACGAATATTCCAATATGCAGGAGATGAAAGATTAGCAGAATCTATCTTACCTTCTTTGAT
AATAATATGTCTGGGATTAATAGCCTCTTTAGCCCTAATACCAAGCTTAAATAACAGAAATAAGTAA

Upstream 100 bases:

>100_bases
ACTTGTCTTTATTGGTAAAGAATTAGATAAAGAAAAAATACTCTCTCAATTAAATGCATGTATTGACAAATAATCACAAA
ATACCAAATTTAAGAATAAA

Downstream 100 bases:

>100_bases
AATTAATATTTAAACTTTAAATATCTTTTTAACTGGATAAATCAAAGCTGCCAATATATCAGAAACTGTTGAAACTAGCC
GATAGCAAAGCAATGAAGCC

Product: putative iron ABC transporter

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: Iron(III)-transport system permease protein fbpB 2 [H]

Number of amino acids: Translated: 528; Mature: 528

Protein sequence:

>528_residues
MNNNRPASKAFKIEKNINFVYNLIGLNNSRYILKYLVVLLTFFILWPLFNLVKEGLYGIQKGSIYLTTANLNDIKGTLLL
LIFSLTLGGFLGVTNGWILANCHFKGRKVLRVCQLIPFATPAYLLAATFIDLGSIYSIRITGMLWGVVIMAFTTYPYVFL
LSLESFEEGGRKQIEACRTLGIGPWKSFFRISLPIAIPSITAGLALMAMEIINELGAVQLLNIPSISAGILESWVEEGEP
SGAIALALFALILVFLLVAIERKSREKSKRWIDGISSVDSPKWELKGINLFLAQVVTFTPPILTLGIPITWAIINIDQIN
QGFNIDLIGLTIRSFSLALAVSLITIFISLILSISKRWHNHQWLNIFTFLSSIGYAIPGSVLALALLSFQGSIWQVNILS
LLIWGYSIRFLAVSKGGLDAGFERISPNIDNAAINLGKNWSEVLLKIHLPLLKGPILVGILLVFVDTIKELPLTFILRPF
DFDTLSVRIFQYAGDERLAESILPSLIIICLGLIASLALIPSLNNRNK

Sequences:

>Translated_528_residues
MNNNRPASKAFKIEKNINFVYNLIGLNNSRYILKYLVVLLTFFILWPLFNLVKEGLYGIQKGSIYLTTANLNDIKGTLLL
LIFSLTLGGFLGVTNGWILANCHFKGRKVLRVCQLIPFATPAYLLAATFIDLGSIYSIRITGMLWGVVIMAFTTYPYVFL
LSLESFEEGGRKQIEACRTLGIGPWKSFFRISLPIAIPSITAGLALMAMEIINELGAVQLLNIPSISAGILESWVEEGEP
SGAIALALFALILVFLLVAIERKSREKSKRWIDGISSVDSPKWELKGINLFLAQVVTFTPPILTLGIPITWAIINIDQIN
QGFNIDLIGLTIRSFSLALAVSLITIFISLILSISKRWHNHQWLNIFTFLSSIGYAIPGSVLALALLSFQGSIWQVNILS
LLIWGYSIRFLAVSKGGLDAGFERISPNIDNAAINLGKNWSEVLLKIHLPLLKGPILVGILLVFVDTIKELPLTFILRPF
DFDTLSVRIFQYAGDERLAESILPSLIIICLGLIASLALIPSLNNRNK
>Mature_528_residues
MNNNRPASKAFKIEKNINFVYNLIGLNNSRYILKYLVVLLTFFILWPLFNLVKEGLYGIQKGSIYLTTANLNDIKGTLLL
LIFSLTLGGFLGVTNGWILANCHFKGRKVLRVCQLIPFATPAYLLAATFIDLGSIYSIRITGMLWGVVIMAFTTYPYVFL
LSLESFEEGGRKQIEACRTLGIGPWKSFFRISLPIAIPSITAGLALMAMEIINELGAVQLLNIPSISAGILESWVEEGEP
SGAIALALFALILVFLLVAIERKSREKSKRWIDGISSVDSPKWELKGINLFLAQVVTFTPPILTLGIPITWAIINIDQIN
QGFNIDLIGLTIRSFSLALAVSLITIFISLILSISKRWHNHQWLNIFTFLSSIGYAIPGSVLALALLSFQGSIWQVNILS
LLIWGYSIRFLAVSKGGLDAGFERISPNIDNAAINLGKNWSEVLLKIHLPLLKGPILVGILLVFVDTIKELPLTFILRPF
DFDTLSVRIFQYAGDERLAESILPSLIIICLGLIASLALIPSLNNRNK

Specific function: Part of the ABC transporter complex fbpABC (TC 3.A.1.10.1) involved in Fe(3+) ions import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1178

COG function: function code P; ABC-type Fe3+ transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transmembrane type-1 domains [H]

Homologues:

Organism=Escherichia coli, GI1788764, Length=155, Percent_Identity=33.5483870967742, Blast_Score=72, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 58481; Mature: 58481

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNNRPASKAFKIEKNINFVYNLIGLNNSRYILKYLVVLLTFFILWPLFNLVKEGLYGIQ
CCCCCCCCHHEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
KGSIYLTTANLNDIKGTLLLLIFSLTLGGFLGVTNGWILANCHFKGRKVLRVCQLIPFAT
CCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCCC
PAYLLAATFIDLGSIYSIRITGMLWGVVIMAFTTYPYVFLLSLESFEEGGRKQIEACRTL
HHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHEEEEHHHHHCCCHHHHHHHHHC
GIGPWKSFFRISLPIAIPSITAGLALMAMEIINELGAVQLLNIPSISAGILESWVEEGEP
CCCCCCHHHEEEECEECHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHCCCC
SGAIALALFALILVFLLVAIERKSREKSKRWIDGISSVDSPKWELKGINLFLAQVVTFTP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECHHHHHHHHHHHHCC
PILTLGIPITWAIINIDQINQGFNIDLIGLTIRSFSLALAVSLITIFISLILSISKRWHN
CHHEECCCEEEEEEEHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
HQWLNIFTFLSSIGYAIPGSVLALALLSFQGSIWQVNILSLLIWGYSIRFLAVSKGGLDA
CHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEHHHHHHHHHHHHEEEEEEECCCCHH
GFERISPNIDNAAINLGKNWSEVLLKIHLPLLKGPILVGILLVFVDTIKELPLTFILRPF
HHHHCCCCCCCHHEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEECCC
DFDTLSVRIFQYAGDERLAESILPSLIIICLGLIASLALIPSLNNRNK
CCCHHEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNNNRPASKAFKIEKNINFVYNLIGLNNSRYILKYLVVLLTFFILWPLFNLVKEGLYGIQ
CCCCCCCCHHEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
KGSIYLTTANLNDIKGTLLLLIFSLTLGGFLGVTNGWILANCHFKGRKVLRVCQLIPFAT
CCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCCC
PAYLLAATFIDLGSIYSIRITGMLWGVVIMAFTTYPYVFLLSLESFEEGGRKQIEACRTL
HHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHEEEEHHHHHCCCHHHHHHHHHC
GIGPWKSFFRISLPIAIPSITAGLALMAMEIINELGAVQLLNIPSISAGILESWVEEGEP
CCCCCCHHHEEEECEECHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHCCCC
SGAIALALFALILVFLLVAIERKSREKSKRWIDGISSVDSPKWELKGINLFLAQVVTFTP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECHHHHHHHHHHHHCC
PILTLGIPITWAIINIDQINQGFNIDLIGLTIRSFSLALAVSLITIFISLILSISKRWHN
CHHEECCCEEEEEEEHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
HQWLNIFTFLSSIGYAIPGSVLALALLSFQGSIWQVNILSLLIWGYSIRFLAVSKGGLDA
CHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEHHHHHHHHHHHHEEEEEEECCCCHH
GFERISPNIDNAAINLGKNWSEVLLKIHLPLLKGPILVGILLVFVDTIKELPLTFILRPF
HHHHCCCCCCCHHEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEECCC
DFDTLSVRIFQYAGDERLAESILPSLIIICLGLIASLALIPSLNNRNK
CCCHHEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800; 7927717 [H]