Click here to switch to the map view.

The map label for this gene is sseA [H]

Identifier: 121639172

GI number: 121639172

Start: 3617336

End: 3618229

Strand: Direct

Name: sseA [H]

Synonym: BCG_3312

Alternate gene names: 121639172

Gene position: 3617336-3618229 (Clockwise)

Preceding gene: 121639171

Following gene: 121639173

Centisome position: 82.69

GC content: 64.21

Gene sequence:

>894_bases
GTGCCGCTTCCCGCAGACCCTAGCCCCACCTTGTCGGCCTACGCCCATCCCGAACGGCTCGTGACCGCCGACTGGTTGTC
GGCACACATGGGCGCGCCGGGCCTGGCGATCGTCGAATCCGACGAGGACGTCTTGCTCTACGACGTCGGCCATATTCCCG
GCGCCGTCAAGATCGACTGGCACACCGACCTCAACGACCCACGGGTGCGCGACTACATCAACGGCGAGCAGTTCGCCGAA
TTGATGGACCGCAAGGGCATCGCCCGCGATGACACCGTGGTGATCTATGGCGACAAGAGCAATTGGTGGGCCGCCTATGC
GTTGTGGGTGTTCACGCTGTTCGGTCACGCCGACGTGCGACTCCTCAACGGCGGCCGTGACCTCTGGCTCGCCGAGCGCC
GGGAAACCACCTTGGACGTCCCGACCAAGACCTGCACCGGTTATCCCGTCGTGCAGCGCAACGATGCACCCATCCGCGCA
TTCAGAGACGACGTGCTGGCCATCCTGGGCGCTCAGCCGCTGATCGACGTACGCTCTCCCGAGGAGTACACCGGCAAGCG
CACCCATATGCCCGATTACCCCGAGGAAGGGGCGCTGCGGGCCGGTCACATCCCCACGGCGGTGCACATTCCGTGGGGGA
AGGCCGCCGACGAAAGTGGACGGTTTCGCAGCCGCGAGGAATTGGAACGGCTCTATGACTTCATAAACCCGGACGACCAA
ACCGTCGTCTATTGCCGCATCGGTGAACGCTCCAGCCATACCTGGTTCGTGCTCACACACCTGCTGGGCAAGGCAGATGT
ACGGAACTACGACGGCTCGTGGACCGAGTGGGGCAACGCCGTGCGAGTGCCGATCGTCGCGGGCGAAGAACCAGGAGTGG
TACCCGTCGTATGA

Upstream 100 bases:

>100_bases
CTGTCCGTCGCCGCACTGTGGGCAGGAAATGCGGGCGGCCCAGCGCACAAGCAGCAGTAGCTTCGGACTGGGCCAGGTCG
CCAGCGGTAGGCTCGATGAT

Downstream 100 bases:

>100_bases
CCGCGCCCGCGAGCCTGCCCGCGCCGCTAGCAGAGGTGGTATCCGACTTCGCCGAAGTCCAGGGTCAAGACAAGCTGAGG
CTGTTGCTGGAATTCGCCAA

Product: putative thiosulfate sulfurtransferase sseA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MPLPADPSPTLSAYAHPERLVTADWLSAHMGAPGLAIVESDEDVLLYDVGHIPGAVKIDWHTDLNDPRVRDYINGEQFAE
LMDRKGIARDDTVVIYGDKSNWWAAYALWVFTLFGHADVRLLNGGRDLWLAERRETTLDVPTKTCTGYPVVQRNDAPIRA
FRDDVLAILGAQPLIDVRSPEEYTGKRTHMPDYPEEGALRAGHIPTAVHIPWGKAADESGRFRSREELERLYDFINPDDQ
TVVYCRIGERSSHTWFVLTHLLGKADVRNYDGSWTEWGNAVRVPIVAGEEPGVVPVV

Sequences:

>Translated_297_residues
MPLPADPSPTLSAYAHPERLVTADWLSAHMGAPGLAIVESDEDVLLYDVGHIPGAVKIDWHTDLNDPRVRDYINGEQFAE
LMDRKGIARDDTVVIYGDKSNWWAAYALWVFTLFGHADVRLLNGGRDLWLAERRETTLDVPTKTCTGYPVVQRNDAPIRA
FRDDVLAILGAQPLIDVRSPEEYTGKRTHMPDYPEEGALRAGHIPTAVHIPWGKAADESGRFRSREELERLYDFINPDDQ
TVVYCRIGERSSHTWFVLTHLLGKADVRNYDGSWTEWGNAVRVPIVAGEEPGVVPVV
>Mature_296_residues
PLPADPSPTLSAYAHPERLVTADWLSAHMGAPGLAIVESDEDVLLYDVGHIPGAVKIDWHTDLNDPRVRDYINGEQFAEL
MDRKGIARDDTVVIYGDKSNWWAAYALWVFTLFGHADVRLLNGGRDLWLAERRETTLDVPTKTCTGYPVVQRNDAPIRAF
RDDVLAILGAQPLIDVRSPEEYTGKRTHMPDYPEEGALRAGHIPTAVHIPWGKAADESGRFRSREELERLYDFINPDDQT
VVYCRIGERSSHTWFVLTHLLGKADVRNYDGSWTEWGNAVRVPIVAGEEPGVVPVV

Specific function: May Be A Sulfotransferase Involved In The Formation Of Thiosulfate. The Rhodanese Activity Of Ssea Is Weak, Its Participation In Detoxification Of Cyanide May Be Small. May Be Involved In The Enhancement Of Serine-Sensitivity. [C]

COG id: COG2897

COG function: function code P; Rhodanese-related sulfurtransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 rhodanese domains [H]

Homologues:

Organism=Homo sapiens, GI194473668, Length=298, Percent_Identity=29.5302013422819, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI17402865, Length=277, Percent_Identity=28.8808664259928, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI61835204, Length=283, Percent_Identity=29.3286219081272, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI194473681, Length=283, Percent_Identity=29.3286219081272, Blast_Score=85, Evalue=8e-17,
Organism=Escherichia coli, GI87082121, Length=286, Percent_Identity=27.972027972028, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI87081967, Length=304, Percent_Identity=26.6447368421053, Blast_Score=81, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI115534702, Length=249, Percent_Identity=28.1124497991968, Blast_Score=79, Evalue=4e-15,

Paralogues:

None

Copy number: 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001763
- InterPro:   IPR001307 [H]

Pfam domain/function: PF00581 Rhodanese [H]

EC number: =2.8.1.1 [H]

Molecular weight: Translated: 33321; Mature: 33190

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS00380 RHODANESE_1 ; PS00683 RHODANESE_2 ; PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLPADPSPTLSAYAHPERLVTADWLSAHMGAPGLAIVESDEDVLLYDVGHIPGAVKIDW
CCCCCCCCCCCEECCCCCCEEEHHHHHHHCCCCCEEEEECCCCEEEEECCCCCCEEEEEE
HTDLNDPRVRDYINGEQFAELMDRKGIARDDTVVIYGDKSNWWAAYALWVFTLFGHADVR
ECCCCCCHHHHHCCHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCEEE
LLNGGRDLWLAERRETTLDVPTKTCTGYPVVQRNDAPIRAFRDDVLAILGAQPLIDVRSP
EEECCCCEEEECCCCCEECCCCCCCCCCCEEECCCCCHHHHHHHHHHHHCCCCEEECCCC
EEYTGKRTHMPDYPEEGALRAGHIPTAVHIPWGKAADESGRFRSREELERLYDFINPDDQ
HHHCCCCCCCCCCCCCCCEECCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCC
TVVYCRIGERSSHTWFVLTHLLGKADVRNYDGSWTEWGNAVRVPIVAGEEPGVVPVV
EEEEEEECCCCCCCEEEEHHHHCCCCCCCCCCCHHHCCCEEEEEEEECCCCCCEECC
>Mature Secondary Structure 
PLPADPSPTLSAYAHPERLVTADWLSAHMGAPGLAIVESDEDVLLYDVGHIPGAVKIDW
CCCCCCCCCCEECCCCCCEEEHHHHHHHCCCCCEEEEECCCCEEEEECCCCCCEEEEEE
HTDLNDPRVRDYINGEQFAELMDRKGIARDDTVVIYGDKSNWWAAYALWVFTLFGHADVR
ECCCCCCHHHHHCCHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCEEE
LLNGGRDLWLAERRETTLDVPTKTCTGYPVVQRNDAPIRAFRDDVLAILGAQPLIDVRSP
EEECCCCEEEECCCCCEECCCCCCCCCCCEEECCCCCHHHHHHHHHHHHCCCCEEECCCC
EEYTGKRTHMPDYPEEGALRAGHIPTAVHIPWGKAADESGRFRSREELERLYDFINPDDQ
HHHCCCCCCCCCCCCCCCEECCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCC
TVVYCRIGERSSHTWFVLTHLLGKADVRNYDGSWTEWGNAVRVPIVAGEEPGVVPVV
EEEEEEECCCCCCCEEEEHHHHCCCCCCCCCCCHHHCCCEEEEEEEECCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]