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The map label for this gene is 121637914

Identifier: 121637914

GI number: 121637914

Start: 2258221

End: 2259060

Strand: Reverse

Name: 121637914

Synonym: BCG_2047c

Alternate gene names: NA

Gene position: 2259060-2258221 (Counterclockwise)

Preceding gene: 121637915

Following gene: 121637913

Centisome position: 51.64

GC content: 67.86

Gene sequence:

>840_bases
ATGAACCAATCACACAAACCCCCATCGATCGTCGTCGGTATTGATGGCTCGAAGCCGGCCGTGCAAGCCGCACTGTGGGC
GGTCGACGAGGCAGCCAGCCGTGACATCCCGCTGCGTCTGCTGTACGCGATCGAACCCGACGATCCCGGGTACGCCGCAC
ACGGCGCGGCGGCTCGCAAACTCGCCGCCGCCGAGAACGCGGTGCGCTACGCGTTCACAGCGGTCGAGGCGGCGGACCGG
CCGGTCAAGGTCGAGGTGGAGATCACCCAGGAGCGGCCGGTCACCTCGTTGATCCGCGCTTCGGCGGCTGCTGCCCTGGT
GTGCGTTGGCGCTATCGGCGTGCACCACTTCCGACCGGAGCGGGTGGGATCTACCGCAGCGGCCCTGGCGTTATCGGCGC
AGTGCCCAGTGGCGATCGTGCGACCCCACCGGGTCCCCATCGGACGCGACGCCGCATGGATCGTCGTCGAGGCGGACGGG
TCGTCCGATATCGGTGTTTTGCTGGGGGCGGTGATGGCCGAAGCACGGCTGCGCGACTCGCCGGTTCGGGTGGTCACCTG
CCGGCAATCCGGAGTGGGCGATACCGGGGACGACGTCCGTGCCAGCCTGGACCGCTGGCTTGCCCGTTGGCAACCACGGT
ATCCCGATGTGCGGGTGCAATCGGCGGCAGTGCACGGCGAGCTGCTGGATTATCTGGCTGGGCTGGGTCGATCGGTACAC
ATGGTGGTGCTCAGCGCGAGCGACCAGGAGCATGTGGAGCAACTTGTGGGAGCGCCGGGCAACGCCGTGTTGCAGGAGGC
CGGCTGCACCCTGCTGGTCGTCGGTCAGCAGTATCTGTGA

Upstream 100 bases:

>100_bases
GCGACGATGTGGAGAGGTTCTTCGAGCTGGCGGCCGAACCCACCGAAGTCGGGCAGGATCAATACGTTTGGCACCCGATC
GTTAACCCGGAAGCCTCGCC

Downstream 100 bases:

>100_bases
CTGTGCCGCTGGGTAGCCAGACCAGTTGGTTGAGCGCAGCTCCGGTGTCAACATAGCTATGTGACACACCCTGACAGGGC
GAACGTTAACCCTGGCAGCC

Product: hypothetical protein

Products: NA

Alternate protein names: USP Rv2028c

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MNQSHKPPSIVVGIDGSKPAVQAALWAVDEAASRDIPLRLLYAIEPDDPGYAAHGAAARKLAAAENAVRYAFTAVEAADR
PVKVEVEITQERPVTSLIRASAAAALVCVGAIGVHHFRPERVGSTAAALALSAQCPVAIVRPHRVPIGRDAAWIVVEADG
SSDIGVLLGAVMAEARLRDSPVRVVTCRQSGVGDTGDDVRASLDRWLARWQPRYPDVRVQSAAVHGELLDYLAGLGRSVH
MVVLSASDQEHVEQLVGAPGNAVLQEAGCTLLVVGQQYL

Sequences:

>Translated_279_residues
MNQSHKPPSIVVGIDGSKPAVQAALWAVDEAASRDIPLRLLYAIEPDDPGYAAHGAAARKLAAAENAVRYAFTAVEAADR
PVKVEVEITQERPVTSLIRASAAAALVCVGAIGVHHFRPERVGSTAAALALSAQCPVAIVRPHRVPIGRDAAWIVVEADG
SSDIGVLLGAVMAEARLRDSPVRVVTCRQSGVGDTGDDVRASLDRWLARWQPRYPDVRVQSAAVHGELLDYLAGLGRSVH
MVVLSASDQEHVEQLVGAPGNAVLQEAGCTLLVVGQQYL
>Mature_279_residues
MNQSHKPPSIVVGIDGSKPAVQAALWAVDEAASRDIPLRLLYAIEPDDPGYAAHGAAARKLAAAENAVRYAFTAVEAADR
PVKVEVEITQERPVTSLIRASAAAALVCVGAIGVHHFRPERVGSTAAALALSAQCPVAIVRPHRVPIGRDAAWIVVEADG
SSDIGVLLGAVMAEARLRDSPVRVVTCRQSGVGDTGDDVRASLDRWLARWQPRYPDVRVQSAAVHGELLDYLAGLGRSVH
MVVLSASDQEHVEQLVGAPGNAVLQEAGCTLLVVGQQYL

Specific function: Unknown

COG id: COG0589

COG function: function code T; Universal stress protein UspA and related nucleotide-binding proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the universal stress protein A family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y2028_MYCTU (O53474)

Other databases:

- EMBL:   AE000516
- EMBL:   BX842578
- PIR:   C70942
- RefSeq:   NP_216544.1
- RefSeq:   NP_336552.1
- ProteinModelPortal:   O53474
- SMR:   O53474
- EnsemblBacteria:   EBMYCT00000003660
- EnsemblBacteria:   EBMYCT00000070380
- GeneID:   888494
- GeneID:   924666
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT2087
- KEGG:   mtu:Rv2028c
- TIGR:   MT2087
- TubercuList:   Rv2028c
- GeneTree:   EBGT00050000015432
- HOGENOM:   HBG733992
- OMA:   QGRIGST
- ProtClustDB:   CLSK791573
- InterPro:   IPR014729
- InterPro:   IPR006015
- InterPro:   IPR006016
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01438

Pfam domain/function: PF00582 Usp

EC number: NA

Molecular weight: Translated: 29442; Mature: 29442

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQSHKPPSIVVGIDGSKPAVQAALWAVDEAASRDIPLRLLYAIEPDDPGYAAHGAAARK
CCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCHHHHH
LAAAENAVRYAFTAVEAADRPVKVEVEITQERPVTSLIRASAAAALVCVGAIGVHHFRPE
HHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHH
RVGSTAAALALSAQCPVAIVRPHRVPIGRDAAWIVVEADGSSDIGVLLGAVMAEARLRDS
HCCCHHHHHEECCCCCEEEECCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCC
PVRVVTCRQSGVGDTGDDVRASLDRWLARWQPRYPDVRVQSAAVHGELLDYLAGLGRSVH
CEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHCCCEEE
MVVLSASDQEHVEQLVGAPGNAVLQEAGCTLLVVGQQYL
EEEEECCCHHHHHHHHCCCCHHHHHHCCCEEEEECCCCC
>Mature Secondary Structure
MNQSHKPPSIVVGIDGSKPAVQAALWAVDEAASRDIPLRLLYAIEPDDPGYAAHGAAARK
CCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCHHHHH
LAAAENAVRYAFTAVEAADRPVKVEVEITQERPVTSLIRASAAAALVCVGAIGVHHFRPE
HHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHH
RVGSTAAALALSAQCPVAIVRPHRVPIGRDAAWIVVEADGSSDIGVLLGAVMAEARLRDS
HCCCHHHHHEECCCCCEEEECCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCC
PVRVVTCRQSGVGDTGDDVRASLDRWLARWQPRYPDVRVQSAAVHGELLDYLAGLGRSVH
CEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHCCCEEE
MVVLSASDQEHVEQLVGAPGNAVLQEAGCTLLVVGQQYL
EEEEECCCHHHHHHHHCCCCHHHHHHCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036