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The map label for this gene is ureG

Identifier: 121637755

GI number: 121637755

Start: 2101299

End: 2101973

Strand: Direct

Name: ureG

Synonym: BCG_1888

Alternate gene names: 121637755

Gene position: 2101299-2101973 (Clockwise)

Preceding gene: 121637754

Following gene: 121637756

Centisome position: 48.03

GC content: 67.26

Gene sequence:

>675_bases
ATGGCAACGCATTCCCATCCCCACTCGCACACCGTGCCCGCTCGGCCAAGGCGGGTCCGCAAACCGGGCGAGCCACTGCG
CATCGGCGTCGGCGGCCCGGTCGGCTCCGGCAAGACCGCACTGGTGGCGGCGCTGTGCCGGCAATTGCGGGGAGAGCTGT
CGCTGGCGGTGCTGACCAACGACATCTACACCACCGAAGACGCCGACTTCTTGCGCACACATGCGGTGCTGCCAGACGAC
CGGATCGCGGCCGTGCAGACCGGCGGCTGCCCGCACACCGCGATCCGCGACGACATCACCGCCAACCTGGATGCGATCGA
CGAGTTGATGGCCGCCCACGACGCGTTGGACCTGATCCTGGTCGAATCCGGCGGCGATAACCTCACGGCCACCTTCTCTT
CGGGGCTGGTGGATGCGCAGATCTTCGTCATTGACGTTGCCGGCGGCGACAAGGTGCCGCGCAAGGGCGGGCCGGGGGTG
ACCTATTCGGATTTGTTGGTAGTCAACAAGACTGACCTGGCTGCATTGGTGGGCGCCGACCTGGCGGTGATGGCCCGCGA
TGCGGACGCGGTGCGCGACGGCCGCCCGACGGTGCTGCAATCGTTGACCGAGGACCCAGCTGCCAGCGATGTCGTGGCCT
GGGTTCGTAGTCAACTGGCCGCCGATGGAGTCTAG

Upstream 100 bases:

>100_bases
ACAGCCGGACTGGCAGACTTGTCTGATCCGCTGCTGGACACGCTCGCCCAGCGGCATGACGAGCGCGTGCGTCCCCTGTT
CGTTTCCTGAAAGGTAAGGC

Downstream 100 bases:

>100_bases
TGTTCTGGTGGTCGCGTCGCCGAATCGGTTGCCGCGCATCGACTGTCGGGGCGGTGTCCAGGCACGCCGAACCGCGCCCG
ACACGGTGCACCTGGTGTCG

Product: urease accessory protein ureG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 224; Mature: 223

Protein sequence:

>224_residues
MATHSHPHSHTVPARPRRVRKPGEPLRIGVGGPVGSGKTALVAALCRQLRGELSLAVLTNDIYTTEDADFLRTHAVLPDD
RIAAVQTGGCPHTAIRDDITANLDAIDELMAAHDALDLILVESGGDNLTATFSSGLVDAQIFVIDVAGGDKVPRKGGPGV
TYSDLLVVNKTDLAALVGADLAVMARDADAVRDGRPTVLQSLTEDPAASDVVAWVRSQLAADGV

Sequences:

>Translated_224_residues
MATHSHPHSHTVPARPRRVRKPGEPLRIGVGGPVGSGKTALVAALCRQLRGELSLAVLTNDIYTTEDADFLRTHAVLPDD
RIAAVQTGGCPHTAIRDDITANLDAIDELMAAHDALDLILVESGGDNLTATFSSGLVDAQIFVIDVAGGDKVPRKGGPGV
TYSDLLVVNKTDLAALVGADLAVMARDADAVRDGRPTVLQSLTEDPAASDVVAWVRSQLAADGV
>Mature_223_residues
ATHSHPHSHTVPARPRRVRKPGEPLRIGVGGPVGSGKTALVAALCRQLRGELSLAVLTNDIYTTEDADFLRTHAVLPDDR
IAAVQTGGCPHTAIRDDITANLDAIDELMAAHDALDLILVESGGDNLTATFSSGLVDAQIFVIDVAGGDKVPRKGGPGVT
YSDLLVVNKTDLAALVGADLAVMARDADAVRDGRPTVLQSLTEDPAASDVVAWVRSQLAADGV

Specific function: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by ureG

COG id: COG0378

COG function: function code OK; Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ureG family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UREG_MYCBO (P0A665)

Other databases:

- EMBL:   BX248340
- RefSeq:   NP_855535.1
- ProteinModelPortal:   P0A665
- SMR:   P0A665
- EnsemblBacteria:   EBMYCT00000017129
- GeneID:   1093009
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb1883
- GeneTree:   EBGT00050000016845
- HOGENOM:   HBG364734
- OMA:   DDIPRKG
- ProtClustDB:   CLSK871974
- BioCyc:   MBOV233413:MB1883-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01389
- InterPro:   IPR003495
- InterPro:   IPR012202
- InterPro:   IPR004400
- PIRSF:   PIRSF005624
- TIGRFAMs:   TIGR00101

Pfam domain/function: PF02492 cobW

EC number: NA

Molecular weight: Translated: 23349; Mature: 23217

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATHSHPHSHTVPARPRRVRKPGEPLRIGVGGPVGSGKTALVAALCRQLRGELSLAVLTN
CCCCCCCCCCCCCCCCHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCEEEEEEEC
DIYTTEDADFLRTHAVLPDDRIAAVQTGGCPHTAIRDDITANLDAIDELMAAHDALDLIL
CCCCCCCHHHHHHHCCCCCCCEEEEECCCCCCHHHHHCHHCCHHHHHHHHHHHCCEEEEE
VESGGDNLTATFSSGLVDAQIFVIDVAGGDKVPRKGGPGVTYSDLLVVNKTDLAALVGAD
EECCCCEEEEEECCCCEEEEEEEEEECCCCCCCCCCCCCCEECCEEEECCCHHHHHHCCC
LAVMARDADAVRDGRPTVLQSLTEDPAASDVVAWVRSQLAADGV
EEEEECCCHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ATHSHPHSHTVPARPRRVRKPGEPLRIGVGGPVGSGKTALVAALCRQLRGELSLAVLTN
CCCCCCCCCCCCCCCHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCEEEEEEEC
DIYTTEDADFLRTHAVLPDDRIAAVQTGGCPHTAIRDDITANLDAIDELMAAHDALDLIL
CCCCCCCHHHHHHHCCCCCCCEEEEECCCCCCHHHHHCHHCCHHHHHHHHHHHCCEEEEE
VESGGDNLTATFSSGLVDAQIFVIDVAGGDKVPRKGGPGVTYSDLLVVNKTDLAALVGAD
EECCCCEEEEEECCCCEEEEEEEEEECCCCCCCCCCCCCCEECCEEEECCCHHHHHHCCC
LAVMARDADAVRDGRPTVLQSLTEDPAASDVVAWVRSQLAADGV
EEEEECCCHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972