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The map label for this gene is ureF

Identifier: 121637754

GI number: 121637754

Start: 2100653

End: 2101288

Strand: Direct

Name: ureF

Synonym: BCG_1887

Alternate gene names: 121637754

Gene position: 2100653-2101288 (Clockwise)

Preceding gene: 121637753

Following gene: 121637755

Centisome position: 48.02

GC content: 71.07

Gene sequence:

>636_bases
ATGACCTCGCTGGCCGTGCTGCTCACCCTCGCCGACTCGCGGCTGCCCACGGGTGCGCACGTGCACTCGGGCGGCATCGA
AGAAGCCATCGCCGCCGGCTTGGTGACCGGCCTGGCCACCCTGGAAGCGTTCCTGAAACGGCGGGTCCGCACCCACGGCC
TGCTGACGGCGTCCATCGCGGCCGCGGTGCACCGGGGCGAGCTGGCCGTCGACGACGCCGACCGGGAAACCGACGCGCGC
ACACCGGCTCCCGCGGCCAGACACGCCTCACGCAGCCAGGGCCGCGGGCTGATCAGGCTGGCACGGCGGGTGTGGCCCGA
TTCCGGCTGGGAGGAACTGGGCCCGAGGCCGCATCTGGCGGTTGTGGCCGGACGGGTCGGCGCGCTGAGCGGGCTGGCGC
CCGAGCACAACGCCTTGCACCTCGTCTACATCACAATGACCGGCTCGGCCATCGCCGCCCAGCGACTGCTGGCGCTAGAT
CCCGCCGAAGTGACCGTGGTGACCTTCCAGCTGTCCGAACTGTGCGAGCAGATCGCGCAGGAGGCCACAGCCGGACTGGC
AGACTTGTCTGATCCGCTGCTGGACACGCTCGCCCAGCGGCATGACGAGCGCGTGCGTCCCCTGTTCGTTTCCTGA

Upstream 100 bases:

>100_bases
AGGTCGATCCCGACACCTTCACCGTGCGAATCGACGGCCAGGTGTGGCAACCGCAGCCGGCCGCCGAACTACCTATGACA
CAACGGTATTTCCTGTTCTA

Downstream 100 bases:

>100_bases
AAGGTAAGGCATGGCAACGCATTCCCATCCCCACTCGCACACCGTGCCCGCTCGGCCAAGGCGGGTCCGCAAACCGGGCG
AGCCACTGCGCATCGGCGTC

Product: urease accessory protein uref

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 211; Mature: 210

Protein sequence:

>211_residues
MTSLAVLLTLADSRLPTGAHVHSGGIEEAIAAGLVTGLATLEAFLKRRVRTHGLLTASIAAAVHRGELAVDDADRETDAR
TPAPAARHASRSQGRGLIRLARRVWPDSGWEELGPRPHLAVVAGRVGALSGLAPEHNALHLVYITMTGSAIAAQRLLALD
PAEVTVVTFQLSELCEQIAQEATAGLADLSDPLLDTLAQRHDERVRPLFVS

Sequences:

>Translated_211_residues
MTSLAVLLTLADSRLPTGAHVHSGGIEEAIAAGLVTGLATLEAFLKRRVRTHGLLTASIAAAVHRGELAVDDADRETDAR
TPAPAARHASRSQGRGLIRLARRVWPDSGWEELGPRPHLAVVAGRVGALSGLAPEHNALHLVYITMTGSAIAAQRLLALD
PAEVTVVTFQLSELCEQIAQEATAGLADLSDPLLDTLAQRHDERVRPLFVS
>Mature_210_residues
TSLAVLLTLADSRLPTGAHVHSGGIEEAIAAGLVTGLATLEAFLKRRVRTHGLLTASIAAAVHRGELAVDDADRETDART
PAPAARHASRSQGRGLIRLARRVWPDSGWEELGPRPHLAVVAGRVGALSGLAPEHNALHLVYITMTGSAIAAQRLLALDP
AEVTVVTFQLSELCEQIAQEATAGLADLSDPLLDTLAQRHDERVRPLFVS

Specific function: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter

COG id: COG0830

COG function: function code O; Urease accessory protein UreF

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ureF family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UREF_MYCBO (Q7VET6)

Other databases:

- EMBL:   BX248340
- RefSeq:   NP_855534.1
- EnsemblBacteria:   EBMYCT00000017180
- GeneID:   1093005
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb1882
- GeneTree:   EBGT00050000015691
- HOGENOM:   HBG709295
- OMA:   GAHQPVV
- ProtClustDB:   CLSK871973
- BioCyc:   MBOV233413:MB1882-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01385
- InterPro:   IPR002639
- PIRSF:   PIRSF009467

Pfam domain/function: PF01730 UreF

EC number: NA

Molecular weight: Translated: 22338; Mature: 22207

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSLAVLLTLADSRLPTGAHVHSGGIEEAIAAGLVTGLATLEAFLKRRVRTHGLLTASIA
CCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAVHRGELAVDDADRETDARTPAPAARHASRSQGRGLIRLARRVWPDSGWEELGPRPHLA
HHHHCCCEEECCCCCCCCCCCCCCHHHHCHHHCCCHHHHHHHHHCCCCCHHHHCCCCCCE
VVAGRVGALSGLAPEHNALHLVYITMTGSAIAAQRLLALDPAEVTVVTFQLSELCEQIAQ
EHHHHHHHHCCCCCCCCCEEEEEEEECCCHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHH
EATAGLADLSDPLLDTLAQRHDERVRPLFVS
HHHHCHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TSLAVLLTLADSRLPTGAHVHSGGIEEAIAAGLVTGLATLEAFLKRRVRTHGLLTASIA
CHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAVHRGELAVDDADRETDARTPAPAARHASRSQGRGLIRLARRVWPDSGWEELGPRPHLA
HHHHCCCEEECCCCCCCCCCCCCCHHHHCHHHCCCHHHHHHHHHCCCCCHHHHCCCCCCE
VVAGRVGALSGLAPEHNALHLVYITMTGSAIAAQRLLALDPAEVTVVTFQLSELCEQIAQ
EHHHHHHHHCCCCCCCCCEEEEEEEECCCHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHH
EATAGLADLSDPLLDTLAQRHDERVRPLFVS
HHHHCHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972