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The map label for this gene is ilvE [H]

Identifier: 121636736

GI number: 121636736

Start: 936845

End: 937714

Strand: Direct

Name: ilvE [H]

Synonym: BCG_0864

Alternate gene names: 121636736

Gene position: 936845-937714 (Clockwise)

Preceding gene: 121636733

Following gene: 121636742

Centisome position: 21.42

GC content: 66.55

Gene sequence:

>870_bases
GTGGTGGTCACGCTTGACGGTGAGATCCTGCAGCCGGGTATGCCGCTGCTGCACGCCGATGATCTTGCCGCTGTGCGGGG
GGATGGCGTTTTCGAGACACTGCTGGTGCGCGACGGCCGAGCCTGTCTGGTTGAAGCGCACCTGCAGCGGCTGACCCAAT
CAGCCAGGTTGATGGACCTTCCCGAACCGGATCTCCCCAGGTGGCGCCGCGCGGTCGAGGTGGCAACGCAGCGGTGGGTG
GCTAGCACCGCTGACGAGGGCGCGCTGCGCTTGATCTACAGTCGCGGTCGGGAGGGCGGCTCGGCGCCGACGGCCTATGT
CATGGTCAGTCCGGTCCCGGCGCGAGTTATCGGGGCCCGCCGCGATGGTGTGTCGGCGATCACGCTGGACCGCGGTTTGC
CGGCTGACGGTGGCGACGCCATGCCGTGGCTGATGGCCAGCGCCAAAACACTGTCCTATGCGGTGAACATGGCCGTCCTG
CGTCATGCCGCCCGGCAGGGCGCCGGCGACGTCATCTTCGTCAGCACGGACGGCTACGTCCTGGAAGGCCCTCGCTCGAC
GGTGGTGATCGCCACCGACGGTGACCAAGGGGGCGGGAACCCCTGCTTGCTGACGCCGCCTCCGTGGTATCCAATCCTGC
GGGGAACCACGCAACAAGCGCTCTTCGAAGTGGCCCGCGCGAAAGGCTACGACTGCGACTACCGTGCCCTACGCGTCGCC
GATCTCTTCGATTCCCAAGGTATTTGGTTGGTATCGAGCATGACTCTGGCCGCCCGCGTACACACCCTGGACGGGCGGCG
ATTACCCCGCACCCCGATCGCTGAGGTGTTTGCCGAATTGGTGGACGCCGCTATTGTCAGCGACCGGTGA

Upstream 100 bases:

>100_bases
GGCAGGGACTGCGGCCACACAACAACTCTACGAAAAGCCGCGCTCGGCCTCGTTGACCAGCGTGCAGCTAGGCTGCAGGG
ACATGTTGAGGCAGACGGGC

Downstream 100 bases:

>100_bases
TACGGCAACCTCTGTTGTGGTCAGCGCCGGCCATACCGCTCGCCGTTATCCGACGAACCGGGACAACCGCGCCGACAGAT
GTGGTACCAGCCCGCCGTCG

Product: 4-amino-4-deoxychorismate lyase

Products: NA

Alternate protein names: BCAT; Transaminase B [H]

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MVVTLDGEILQPGMPLLHADDLAAVRGDGVFETLLVRDGRACLVEAHLQRLTQSARLMDLPEPDLPRWRRAVEVATQRWV
ASTADEGALRLIYSRGREGGSAPTAYVMVSPVPARVIGARRDGVSAITLDRGLPADGGDAMPWLMASAKTLSYAVNMAVL
RHAARQGAGDVIFVSTDGYVLEGPRSTVVIATDGDQGGGNPCLLTPPPWYPILRGTTQQALFEVARAKGYDCDYRALRVA
DLFDSQGIWLVSSMTLAARVHTLDGRRLPRTPIAEVFAELVDAAIVSDR

Sequences:

>Translated_289_residues
MVVTLDGEILQPGMPLLHADDLAAVRGDGVFETLLVRDGRACLVEAHLQRLTQSARLMDLPEPDLPRWRRAVEVATQRWV
ASTADEGALRLIYSRGREGGSAPTAYVMVSPVPARVIGARRDGVSAITLDRGLPADGGDAMPWLMASAKTLSYAVNMAVL
RHAARQGAGDVIFVSTDGYVLEGPRSTVVIATDGDQGGGNPCLLTPPPWYPILRGTTQQALFEVARAKGYDCDYRALRVA
DLFDSQGIWLVSSMTLAARVHTLDGRRLPRTPIAEVFAELVDAAIVSDR
>Mature_289_residues
MVVTLDGEILQPGMPLLHADDLAAVRGDGVFETLLVRDGRACLVEAHLQRLTQSARLMDLPEPDLPRWRRAVEVATQRWV
ASTADEGALRLIYSRGREGGSAPTAYVMVSPVPARVIGARRDGVSAITLDRGLPADGGDAMPWLMASAKTLSYAVNMAVL
RHAARQGAGDVIFVSTDGYVLEGPRSTVVIATDGDQGGGNPCLLTPPPWYPILRGTTQQALFEVARAKGYDCDYRALRVA
DLFDSQGIWLVSSMTLAARVHTLDGRRLPRTPIAEVFAELVDAAIVSDR

Specific function: Acts on leucine, isoleucine and valine [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300
- InterPro:   IPR005785 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =2.6.1.42 [H]

Molecular weight: Translated: 31141; Mature: 31141

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVTLDGEILQPGMPLLHADDLAAVRGDGVFETLLVRDGRACLVEAHLQRLTQSARLMDL
CEEEECCCEECCCCCEEECCCHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCC
PEPDLPRWRRAVEVATQRWVASTADEGALRLIYSRGREGGSAPTAYVMVSPVPARVIGAR
CCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCEEEEEECCCCHHHHCCC
RDGVSAITLDRGLPADGGDAMPWLMASAKTLSYAVNMAVLRHAARQGAGDVIFVSTDGYV
CCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEE
LEGPRSTVVIATDGDQGGGNPCLLTPPPWYPILRGTTQQALFEVARAKGYDCDYRALRVA
EECCCCEEEEEECCCCCCCCEEEECCCCCCHHHCCCHHHHHHHHHHHCCCCCCHHHEEEE
DLFDSQGIWLVSSMTLAARVHTLDGRRLPRTPIAEVFAELVDAAIVSDR
HHHCCCCEEEEEHHEEEHEEEECCCCCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVVTLDGEILQPGMPLLHADDLAAVRGDGVFETLLVRDGRACLVEAHLQRLTQSARLMDL
CEEEECCCEECCCCCEEECCCHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCC
PEPDLPRWRRAVEVATQRWVASTADEGALRLIYSRGREGGSAPTAYVMVSPVPARVIGAR
CCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCEEEEEECCCCHHHHCCC
RDGVSAITLDRGLPADGGDAMPWLMASAKTLSYAVNMAVLRHAARQGAGDVIFVSTDGYV
CCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEE
LEGPRSTVVIATDGDQGGGNPCLLTPPPWYPILRGTTQQALFEVARAKGYDCDYRALRVA
EECCCCEEEEEECCCCCCCCEEEECCCCCCHHHCCCHHHHHHHHHHHCCCCCCHHHEEEE
DLFDSQGIWLVSSMTLAARVHTLDGRRLPRTPIAEVFAELVDAAIVSDR
HHHCCCCEEEEEHHEEEHEEEECCCCCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]